Caseinomacropeptide specifically stimulates exocrine pancreatic secretion in the anesthetized rat.

abstract：:Neuropeptide Y-containing nerve fibers have previously been demonstrated to innervate the mammalian ovary. These nerve fibers innervate primarily the vasculature. In this study we have developed a method for in vivo measurement of the ovary blood flow rate by means of the 133Xe method. Using this technique we measured...

journal_title：Peptides

authors： Jørgensen JC,Sejrsen P

更新日期：1990-05-01 00:00:00

abstract：:A bradykinin (BK)-related peptide was isolated from heat-denaturated plasma from an elasmobranch fish, the little skate, Leucoraja erinacea after incubation with porcine pancreatic kallikrein. The primary structure of the peptide (H-Gly-Ile-Thr-Ser-Trp-Leu-Pro-Phe-OH; skate BK) shows limited structural similarity to t...

journal_title：Peptides

authors： Anderson WG,Leprince J,Conlon JM

更新日期：2008-08-01 00:00:00

abstract：:The neuropeptide oxytocin (OXT) contributes to the regulation of diverse cognitive and physiological functions including nociception. Indeed, OXT has been reported to be analgesic when administered directly into the brain, the spinal cord, or systemically. Although many authors have reported the analgesic effects of O...

journal_title：Peptides

authors： Russo R,D'Agostino G,Mattace Raso G,Avagliano C,Cristiano C,Meli R,Calignano A

更新日期：2012-11-01 00:00:00

abstract：:Antibodies to the extreme C-terminal pentapeptide of procholecystokinin, YEYPS (in the single letter notation), have been used in radioimmunoassay and immunohistochemistry to characterize the material in rat intestine. There is a single major immunoreactive peptide in intestinal extracts that has the properties of the...

journal_title：Peptides

authors： Jonsson AC,Varro A,Dockray GJ

更新日期：1987-01-01 00:00:00

abstract：:Each of the dynorphin A(1-13) or dynorphin (dyn) treatment groups receiving naloxone showed a significant overall reduction of overt signs compared with the dyn controls. The data suggested that the overt psychomotor effects of dyn in the rhesus monkey were especially prone to blockade by naloxone, and probably involv...

journal_title：Peptides

authors： Aceto MD,Bowman ER

更新日期：1992-07-01 00:00:00

abstract：:A series of Locusta adipokinetic hormone I (AKH-I), < QLNFTPNWGTa, analogues, were synthesized with modifications at the C-terminal threonine residue using a combination of solid- and liquid-phase methodology and evaluated in Locusta migratoria, in a lipid mobilization assay in vivo and an acetate uptake assay in vitr...

journal_title：Peptides

authors： Lee MJ,Goldsworthy GJ,Poulos CP,Velentza A

更新日期：1996-01-01 00:00:00

abstract：:Human bombesin receptors, GRPR and NMBR, are two of the most frequently overexpressed G-protein-coupled-receptors by lung-cancers. Recently, GRPR/NMBR are receiving considerable attention because they act as growth factor receptors often in an autocrine manner in different lung-cancers, affect tumor angiogenesis, thei...

journal_title：Peptides

authors： Moreno P,Mantey SA,Lee SH,Ramos-Álvarez I,Moody TW,Jensen RT

更新日期：2018-03-01 00:00:00

abstract：:125I-Ang I binding to atypical sites on Mycoplasma hyorhinis-contaminated IEC-18 cell membranes increased with increasing pH and [NaCl] (ED50 at 500 mM; maximal 13-fold increase at 2 M NaCl). Alkali metal chlorides and sodium halides increased binding with rank orders of Na+ < K+ < Rb+ < Cs+ = Li+ and F- < Cl- < Br < ...

journal_title：Peptides

authors： Smith RD

更新日期：1999-01-01 00:00:00

abstract：:Ceruletide (CLT: 160 micrograms/kg, SC) produced a relatively long-lasting inhibition of haloperidol (HPD: 2 mg/kg, PO) catalepsy in rats. Neither bilateral vagotomies nor hypophysectomy abolished the anticataleptic effect of CLT. However, (-)-L-364,718 and proglumide blocked the effect of CLT. CLT (160 micrograms/kg)...

journal_title：Peptides

authors： Ibii N,Ikeda M,Takahara Y,Eigyo M,Akiyoshi T,Matsushita A

更新日期：1989-07-01 00:00:00

abstract：:Neurotensin (NT) is a tridecapeptide (less than Glu-Leu-Tyr-Glu-Asn-Lys-Pro-Arg-Arg-Pro-Tyr-Ile-Leu-OH). It has been suggested that the naturally occurring neurotensin in (Gln4)-NT and that it can be hydrolysed to (Glu4)-NT during extraction. The aim of the present study was to determine whether the neurotensin found ...

journal_title：Peptides

authors： Theodorsson-Norheim E

更新日期：1983-07-01 00:00:00

abstract：:Prolactin releasing peptide (PrRP) was originally reported to act in the anterior lobe of the pituitary gland to stimulate prolactin (PRL) release; however, numerous other pharmacologic actions of PrRP have been described. In the central nervous system PrRP inhibits food intake, stimulates sympathetic tone, and activa...

journal_title：Peptides

authors： Samson WK,Taylor MM

更新日期：2006-05-01 00:00:00

abstract：:The aim of this study was to compare the actions of CCK neuropeptides within the nucleus accumbens (N.Acc) of alcohol preferring (Fawn-Hooded, FH) and alcohol nonpreferring (Wistar-Kyoto, WKY) rats. CCK-8S (30-300 nM) facilitated the K(+) stimulated release of [(3)H]dopamine (DA) from N.Acc prisms in both rat strains,...

journal_title：Peptides

authors： Lodge DJ,Short JL,Mercer LD,Beart PM,Lawrence AJ

更新日期：2000-03-01 00:00:00

abstract：:The neuropharmacological basis for d-amphetamine induced paradoxical behavioral thermoregulation remains unclear. This study examined thermoregulatory behavior of rats in a runway device that housed a heat source at one end and in which locomotion along the length of the runway could be observed. Sprague Dawley rats w...

journal_title：Peptides

authors： Yehuda S,Sheleff P

更新日期：1985-03-01 00:00:00

abstract：:Apamin is a neurotoxic octadecapeptide from bee venom, which has been shown to inhibit the non-adrenergic, non-cholinergic inhibitory innervation of the smooth muscle of the gut. Since vasoactive intestinal polypeptide (VIP) has been proposed as a possible inhibitory neurotransmitter, the effect of apamin on the recep...

journal_title：Peptides

authors： Fahrenkrug J,Gammeltoft S,Staun-Olsen P,Ottesen B,Sjöquist A

更新日期：1983-03-01 00:00:00

abstract：:Defense peptides play a crucial role in insect innate immunity against invading pathogens. From the hemolymph of immune-challenged greater wax moth, Galleria mellonella (Gm) larvae, eight peptides were isolated and characterized. Purified Gm peptides differ considerably in amino acid sequences, isoelectric point value...

journal_title：Peptides

authors： Cytryńska M,Mak P,Zdybicka-Barabas A,Suder P,Jakubowicz T

更新日期：2007-03-01 00:00:00

abstract：:We have previously shown that brief, vena caval infusion of gastrin-releasing peptide1-27 (GRP), delivered shortly (5 min) after the end of the first spontaneous nocturnal meal, significantly prolongs the postprandial intermeal interval (IMI) without affecting the size of the subsequent meal in freely-feeding rats. In...

journal_title：Peptides

authors： Rushing PA,Gibbs J

更新日期：1998-01-01 00:00:00

abstract：:The aim of the present study was to correlate the development of the renin angiotensin system (RAS) in the kidney of the rat with the development of genetic hypertension. Immature (1-week-old) and adult (12-week-old) normotensive Wistar-Kyoto (WKY) and spontaneously hypertensive kidney rats (SHR) were used for quantif...

journal_title：Peptides

authors： Correa FM,Viswanathan M,Ciuffo GM,Tsutsumi K,Saavedra JM

更新日期：1995-01-01 00:00:00

abstract：:By immunohistochemistry it was found that PHI- and VIP-like immunoreactivity (-IR) occurred in the same autonomic neurons in the upper respiratory tract, tongue and salivary glands with associated ganglia in rat, guinea-pig, cat, pig and man. VIP- and PHI-like immunoreactivity was also found in similar locations in th...

journal_title：Peptides

authors： Lundberg JM,Fahrenkrug J,Hökfelt T,Martling CR,Larsson O,Tatemoto K,Anggård A

更新日期：1984-05-01 00:00:00

abstract：:The binding and internalization of a cytotoxic analogue of luteinizing hormone-releasing hormone (LH-RH), T-98 (agonist [D-Lys6]LH-RH linked to glutaryl-2-(hydroxymethyl)anthraquinone), by rat anterior pituitary cells was investigated. Analogue T-98 was bound to pituitary membrane binding sites for LH-RH with a high a...

journal_title：Peptides

authors： Szöke B,Horváth J,Halmos G,Rékási Z,Groot K,Nagy A,Schally AV

更新日期：1994-01-01 00:00:00

abstract：:beta-Lactotensin (beta-LT) is a bioactive peptide derived from bovine milk beta-lactoglobulin and is a natural ligand for neurotensin receptors. We examined the effect of beta-LT on restraint stress and fear memory in mice. Mice subjected to acute restraint stress exhibited a decreased number of head-dips and increase...

journal_title：Peptides

authors： Yamauchi R,Wada E,Yamada D,Yoshikawa M,Wada K

更新日期：2006-12-01 00:00:00

abstract：:Leptin, a hormone secreted by the adipocytes and involved in feeding and energy balance control, has been proposed to modulate alcohol craving in mice and humans. This study evaluated whether leptin modulates alcohol intake in Marchigian Sardinian alcohol-preferring (msP) rats. Rats were offered 10% ethanol either 2h ...

journal_title：Peptides

authors： Polidori C,Luciani F,Fedeli A,Geary N,Massi M

更新日期：2003-09-01 00:00:00

abstract：:Which of Y1-Y5 receptors (Rs) mediate NPY's angiogenic activity was studied using Y2R-null mice and R-specific antagonists. In Y2R-null mice, NPY-induced aortic sprouting and in vivo Matrigel capillary formation were decreased by 50%; Y1R-antagonist blocked the remaining response. NPY-induced sprouting was equally inh...

journal_title：Peptides

authors： Lee EW,Grant DS,Movafagh S,Zukowska Z

更新日期：2003-01-01 00:00:00

abstract：:As the frequent emergence of the resistant bacteria, the development of new agents with a new action mode attracts a great deal of interest. It is now widely accepted that antimicrobial peptides (AMPs) are promising alternatives to conventional antibiotics. In this study, antimicrobial peptide polybia-MPI and its anal...

journal_title：Peptides

authors： Wang K,Yan J,Dang W,Liu X,Chen R,Zhang J,Zhang B,Zhang W,Kai M,Yan W,Yang Z,Xie J,Wang R

更新日期：2013-01-01 00:00:00

abstract：:The neuroendocrine and behavioral effects of Tyr-D-Ala-Gly-Phe-D-Nle-Arg-Phe (DADN), a more stable derivative of the endogenous opiate Met-enkephalin related peptide Met(5)-enkephalin-Arg(6)-Phe(7) were investigated in mice. The behavioral experiments consisted of monitoring the horizontal (square crossing) and vertic...

journal_title：Peptides

authors： Csabafi K,Jászberényi M,Bagosi Z,Tóth G,Wollemann M,Telegdy G

更新日期：2011-08-01 00:00:00

abstract：:Many neuroendocrine peptides that are distributed in amphibian gastrointestinal tract and central nervous system are also found in amphibian skins, and these peptides are classified into skin-gut-brain triangle peptides, such as bombesins, gastrin-releasing peptides. Cholecystokinins (CCKs) are neuroendocrine peptides...

journal_title：Peptides

authors： Liu X,Wang Y,Cheng L,Song Y,Lai R

更新日期：2007-08-01 00:00:00

abstract：:Pinealectomized (PX) and sham animals were administered either AVT (1 ng/kg) or vehicle (1 ml H20). Boxing-kicking-biting episodes were significantly reduced by administration of AVT, F(1,21) = 8.09, p less than 0.009. Crawling under behavior was increased in PXH20 animals (p less than 0.05). Non-aggressive rearing wa...

journal_title：Peptides

authors： Brown R,King MG

更新日期：1984-11-01 00:00:00

abstract：:The central effect of cholecystokinin-octapeptide (CCK), SQ 19,844 or sincalide, on the intake of food and water and on colonic temperature (Tc) was investigated using the broiler cockerel. Four-week old chicks were maintained in a thermoneutral environment of 23-24 degrees C. After food was removed for a 24 hr interv...

journal_title：Peptides

authors： Denbow DM,Myers RD

更新日期：1982-09-01 00:00:00

abstract：:Naltrexone, an opiate antagonist, was administered to young obese (ob/ob) and lean mice for five weeks. Animals had continuous access to food and received 10 mg/kg SC twice daily with equivalent volumes of saline given to controls. The effects on body weight, and pituitary and plasma levels of beta-endorphin-like mate...

journal_title：Peptides

authors： Recant L,Voyles NR,Luciano M,Pert CB

更新日期：1980-01-01 00:00:00

abstract：:The biosynthetic activity of rat intermediate lobe melanotropes in vivo is inhibited by stimulation of dopamine D2 receptors. Individual melanotropes are innervated differentially by dopaminergic axons and vary in their levels of pro-opiomelanocortin (POMC) mRNA. We tested the hypothesis that placement of the lobe in ...

journal_title：Peptides

authors： Beatty DM,Morris SJ,Chronwall BM

更新日期：1998-01-01 00:00:00

abstract：:Natriuretic peptide receptor C (NPR-C) is known to bind all natriuretic peptides with similar affinity. Given their biological role it is interesting that natriuretic peptides and their activated guanylate cyclases (NPR-A and NPR-B) are expressed in retinal amacrine cells. The purpose of this study is to examine the p...

journal_title：Peptides

authors： Abdelalim EM,Tooyama I

更新日期：2010-01-01 00:00:00