Expression and function of members of a divergent nuclear receptor family in Caenorhabditis elegans.

abstract：:Embryonic development involves a series of cell adhesive interactions that provide mechanical and instructive information required for morphogenesis. The ADAMs family of membrane-anchored proteins, containing a disintegrin and metalloprotease domain, is well suited for participating in such developmental events. They ...

journal_title：Developmental biology

authors： Alfandari D,Wolfsberg TG,White JM,DeSimone DW

更新日期：1997-02-15 00:00:00

abstract：:Morphogenesis of the cartilaginous otic capsule is directed by interactions between the epithelial anlage of the membranous labyrinth (otocyst) and its associated periotic mesenchyme. Utilizing a developmental series of high-density (micromass) cultures of periotic mesenchyme to model capsule chondrogenesis, we have s...

journal_title：Developmental biology

authors： Frenz DA,Van De Water TR

更新日期：1991-03-01 00:00:00

abstract：:During meiotic maturation or after fertilization of invertebrate and vertebrate oocytes, many of the quiescent stored mRNAs are recruited into polysomes. In the clam, Spisula solidissima, such masked messages include the abundant mRNAs encoding cyclin A and the small subunit of ribonucleotide reductase. We have previo...

journal_title：Developmental biology

authors： Walker J,Dale M,Standart N

更新日期：1996-01-10 00:00:00

abstract：:This study describes the temporal pattern of posterior positional identity in mouse limb bud cells. To do this wedges of tissue from the posterior edge of mouse limb buds at various stages (limb stages: Wanek et al., 1989b. J. Exp. Zool. 249, 41-49) were grafted to the anterior edge of a host chick embryo wing bud. Gr...

journal_title：Developmental biology

authors： Wanek N,Bryant SV

更新日期：1991-10-01 00:00:00

abstract：:The relationship among neuronal type, position, and time course of development of identified neurons was examined in the zebrafish (Brachydanio rerio). The cells studied, the reticulospinal neurons Mauthner, MiM1, and MiV1, are located within the same small region in the hindbrain, differ stereotypically in their posi...

journal_title：Developmental biology

authors： Mendelson B

更新日期：1985-12-01 00:00:00

abstract：:After induction and specification in the ectoderm, at the border of the neural plate, the neural crest (NC) population leaves its original territory through a delamination process. Soon afterwards, the NC cells migrate throughout the embryo and colonize a myriad of tissues and organs where they settle and differentiat...

journal_title：Developmental biology

authors： Theveneau E,Mayor R

更新日期：2012-06-01 00:00:00

abstract：:The trkA gene encodes the tyrosine kinase receptor that transduces the NGF signal. We have used a defective herpes simplex virus-1 (HSV-1) vector containing a full-length rat trkA sequence (pHSVtrkA) to express NGF receptors in primary cultures of neonatal nodose neurons and embryonic spinal motor neurons which are no...

journal_title：Developmental biology

authors： Xu H,Federoff H,Maragos J,Parada LF,Kessler JA

更新日期：1994-05-01 00:00:00

abstract：:The corepressor SMRT acts on a range of transcription factors, including the retinoid and thyroid hormone nuclear receptors. The carboxy-terminal region of SMRT contains CoRNR box motifs that mediate these interactions. We have shown, in Xenopus, that SMRT can exist as isoforms containing either two or three CoRNR box...

journal_title：Developmental biology

authors： Malartre M,Short S,Sharpe C

更新日期：2006-04-15 00:00:00

abstract：:Suppression of wing fate and specification of haltere fate in Drosophila by the homeotic gene Ultrabithorax is a classical example of Hox regulation of serial homology (Lewis, E.B. 1978. Nature 276, 565-570) and has served as a paradigm for understanding homeotic gene function. We have used DNA microarray analyses to ...

journal_title：Developmental biology

authors： Mohit P,Makhijani K,Madhavi MB,Bharathi V,Lal A,Sirdesai G,Reddy VR,Ramesh P,Kannan R,Dhawan J,Shashidhara LS

更新日期：2006-03-15 00:00:00

abstract：:Mutations in the Pax6 gene disrupt telencephalic development, resulting in a thin cortical plate, expansion of proliferative layers, and the absence of the olfactory bulb. The primary defect in the neuronal cell population of the developing cerebral cortex was analysed by using mouse chimeras containing a mixture of w...

journal_title：Developmental biology

authors： Talamillo A,Quinn JC,Collinson JM,Caric D,Price DJ,West JD,Hill RE

更新日期：2003-03-01 00:00:00

abstract：:The germinal vesicle (GV) of starfish oocytes stays just beneath the oocyte cortex at the presumptive animal pole during the long period of oogenesis. We subjected oocytes to a centrifugal force field to detach the GV from the cortex. The association between the cortex and the GV persisted and withstood a small amount...

journal_title：Developmental biology

authors： Miyazaki A,Kamitsubo E,Nemoto SI

更新日期：2000-02-15 00:00:00

abstract：:In mammalian and amphibian oocytes, the meiotic arrest at the G2/M transition is dependent on cAMP regulation. Because genetic inactivation of a phosphodiesterase expressed in oocytes prevents reentry into the cell cycle, suggesting autonomous cAMP synthesis, we investigated the presence and properties of the G-protei...

journal_title：Developmental biology

authors： Hinckley M,Vaccari S,Horner K,Chen R,Conti M

更新日期：2005-11-15 00:00:00

abstract：:Embryonic morphogenesis relies on the intrinsic ability of cells, often through remodeling the cytoskeleton, to shape epithelial tissues during development. Epithelial invagination is an example of morphogenesis that depends on this remodeling but the cellular mechanisms driving arrangement of cytoskeletal elements ne...

journal_title：Developmental biology

authors： Houssin NS,Martin JB,Coppola V,Yoon SO,Plageman TF Jr

更新日期：2020-06-01 00:00:00

abstract：:The left-right body axis is coordinately aligned with the orthogonal dorsoventral and anterioposterior body axes. The developmental mechanisms that regulate axis coordination are unknown. Here it is shown that the cardiac left-right orientation in zebrafish (Danio rerio) is randomized in notochord-defective no tail an...

journal_title：Developmental biology

authors： Danos MC,Yost HJ

更新日期：1996-07-10 00:00:00

abstract：:The categorical data set is an important data class in experimental biology and contains data separable into several mutually exclusive categories. Unlike measurement of a continuous variable, categorical data cannot be analyzed with methods such as the Student's t-test. Thus, these data require a different method of ...

journal_title：Developmental biology

authors： Xu B,Feng X,Burdine RD

更新日期：2010-12-01 00:00:00

abstract：:Sequence analysis of cDNA clones encoding fibronectin (FN) from Xenopus laevis reveals extensive amino acid identities with other vertebrate FNs, including the presence of the Arg-Gly-Asp (RGD) cell attachment site in type III-10 and of a second, cell-binding site (EILDV) in the alternative spliced V region of the pro...

journal_title：Developmental biology

authors： DeSimone DW,Norton PA,Hynes RO

更新日期：1992-02-01 00:00:00

abstract：:We investigated whether the inhibition of proteoglycan synthesis and salivary branching morphogenesis by beta-D-xyloside was related to the deposition and processing of newly synthesized glycosaminoglycans at the basal epithelial surface that correlates with normal branching activity. Forty eight-hour cultures of cont...

journal_title：Developmental biology

authors： Spooner BS,Bassett K,Stokes B

更新日期：1985-05-01 00:00:00

abstract：:Pax3 is a transcription factor expressed in somitic mesoderm, dorsal neural tube and pre-migratory neural crest during embryonic development. We have previously identified cis-acting enhancer elements within the proximal upstream genomic region of Pax3 that are sufficient to direct functional expression of Pax3 in neu...

journal_title：Developmental biology

authors： Degenhardt KR,Milewski RC,Padmanabhan A,Miller M,Singh MK,Lang D,Engleka KA,Wu M,Li J,Zhou D,Antonucci N,Li L,Epstein JA

更新日期：2010-03-15 00:00:00

abstract：:We have isolated a cDNA of the DEAD protein family from a Xenopus ovary cDNA library. Northern hybridization revealed that the mRNA corresponding to the cDNA [XVLG1 (Xenopus vasa-like gene)] was specifically expressed in adult testis and ovary. The deduced amino acid sequence of XVLG1 was relatively homologous to that...

journal_title：Developmental biology

authors： Komiya T,Itoh K,Ikenishi K,Furusawa M

更新日期：1994-04-01 00:00:00

abstract：:Homeotic genes in the Antennapedia Complex of Drosophila specify identity of the posterior head segments; the labial segment requires Sex combs reduced (Scr) for proper development, Deformed (Dfd) specifies maxillary and mandibular identity, and labial is necessary for intercalary segment identity. Although mutations ...

journal_title：Developmental biology

authors： Pederson JD,Kiehart DP,Mahaffey JW

更新日期：1996-11-25 00:00:00

abstract：:Cells anchor to substrates by binding to extracellular matrix (ECM). In addition to this anchoring function however, cell-ECM binding is a mechanism for cells to sense their surroundings and to communicate and coordinate behaviour amongst themselves. Several ECM molecules and their receptors play essential roles in mu...

journal_title：Developmental biology

authors： Thorsteinsdóttir S,Deries M,Cachaço AS,Bajanca F

更新日期：2011-06-15 00:00:00

abstract：:Alkaline phosphatase (AP) activity is expressed in the endodermal cell lineage of ascidian embryos beginning at gastrulation. AP expression is resistant to levels of actinomycin D which completely suppress the appearance of other tissue-specific enzyme and morphological markers including acetylcholinesterase (AchE), a...

journal_title：Developmental biology

authors： Bates WR,Jeffery WR

更新日期：1987-02-01 00:00:00

abstract：:Eye cups from stage 14-28 (E2 to E5) chick and quail embryos consisting of neural retina, lens, and vitreous body were cultured for 1 or 2 days. These eyes expanded by proliferation of the retinal cells and the surface areas of the retinae increased several-fold. The area covered by ganglion cells and axons also expan...

journal_title：Developmental biology

authors： Halfter W,Deiss S

更新日期：1986-04-01 00:00:00

abstract：:Recently, it has been suggested that a mouse sperm-associated protein with properties similar to the inhibitory guanine nucleotide-binding regulatory protein Gi plays an intermediary role in the zona pellucida-induced acrosome reaction (Endo, Y., Lee, M. A., and Kopf, G. S. 1987. Dev. Biol. 119, 210-216). In the prese...

journal_title：Developmental biology

authors： Endo Y,Lee MA,Kopf GS

更新日期：1988-09-01 00:00:00

abstract：:The smaller AB-cell of the 2-cell embryo of Tubifex divides 40 min later than the larger CD-cell. The present study was undertaken to elucidate those factors that are responsible for this cleavage asynchrony. An examination of chromosome cycles showed that the AB-cell entered M-phase 5 min later and spent about 35 min...

journal_title：Developmental biology

authors： Shimizu T

更新日期：1993-05-01 00:00:00

abstract：:Voltage-gated Na(+) and K(+) channels are localized to distinct subcellular domains in mammalian myelinated nerve fibers. Specifically, Na(+) channels are clustered in high densities at nodes of Ranvier, while K(+) channels are found in juxtaparanodal zones just beyond regions of axoglial contact where sequential laye...

journal_title：Developmental biology

authors： Rasband MN,Trimmer JS

更新日期：2001-08-01 00:00:00

abstract：:In developing limb buds, Msx2 transcripts are expressed in the apical ectodermal ridge (AER) and in various regions of the limb mesenchyme. To identify DNA sequences responsible for Msx2 expression in the AER, we characterized the expression of LacZ reporter constructs driven by chicken Msx2 regulatory sequences in tr...

journal_title：Developmental biology

authors： Cheng HC,Wang CK,Upholt WB

更新日期：2004-06-15 00:00:00

abstract：:The task of the visual system is to translate light into neuronal encoded information. This translation of photons into neuronal signals is achieved by photoreceptor neurons (PRs), specialized sensory neurons, located in the eye. Upon perception of light the PRs will send a signal to target neurons, which represent a ...

journal_title：Developmental biology

authors： Sprecher SG,Cardona A,Hartenstein V

更新日期：2011-10-01 00:00:00

abstract：:The chick spinal cord can regenerate following injury until advanced developmental stages. It is conceivable that changes in stem/progenitor cell plasticity contribute to the loss of this capacity, which occurs around E13. We investigated the contribution of proliferation, phenotypic changes in radial glia progenitors...

journal_title：Developmental biology

authors： Whalley K,Gögel S,Lange S,Ferretti P

更新日期：2009-08-15 00:00:00

abstract：:The C-X-C motif ligand 14 (CXCL14) is a recently discovered chemokine that is highly conserved in vertebrates and expressed in various embryonic and adult tissues. CXCL14 signaling has been implicated to function as an antiangiogenic and anticancer agent in adults. However, its function during development is unknown. ...

journal_title：Developmental biology

authors： Ojeda AF,Munjaal RP,Lwigale PY

更新日期：2017-03-01 00:00:00