Abstract：
:Cysticercus fasciolaris, the larval form of Taenia taeniaformis is commonly encountered in rodents most often in mice and rats through contaminated feed and bedding materials. The infection is asymptomatic and is considered harmless, but its presence in the laboratory mice/rats could lead to misinterpretation of results for biological experiments. The course of infection and pathogenesis of induced C. fasciolaris was studied in Swiss albino mice. The number of established cysts were not significantly different during the course of infection. The mean diameter of the cysts and the metacestode were significantly different during the course of infection reaching a maximum size of 8.1 +/- 2.2 mm and 80.4 +/- 20.2 mm, respectively on 45 DPI. Histopathologically, on 15 DPI, the duodenum of the affected mice revealed cross sections of early larval stage of C. fasciolaris. On 30 and 45 DPI, the liver showed tract of migration of C. fasciolaris larvae with a thick zone of inflammatory reaction and encapsulation against mature larvae in liver. The routine spontaneous Cystucercus infection is clinically asymptomatic in these animals and is considered harmless. The present experimental infection also followed the same course resulting only in asymptomatic colonisation of the parasites.
journal_name
Indian J Exp Bioljournal_title
Indian journal of experimental biologyauthors
Jithendran KP,Somvanshi Rsubject
Has Abstractpub_date
1998-05-01 00:00:00pages
523-5issue
5eissn
0019-5189issn
0975-1009journal_volume
36pub_type
杂志文章abstract：:In order to find out the effect of chronic ethanol administration on testicular antioxidant system and steroidogenic enzyme activity, male rats fed with ethanol 1.6g/kg body weight per day for four weeks were studied. Besides a drastic reduction in body and testis weight, there was decrease in ascorbic acid, reduced g...
journal_title：Indian journal of experimental biology
pub_type： 杂志文章
doi：
更新日期：2005-05-01 00:00:00
abstract：:Capsaicin exerts a stabilizing effect on erythrocytes making them more resistant to lysis under hypotonic stress. The protective action of capsaicin on osmotic fragility (OF) was not receptor mediated since no dose responsive effect was observed. The results suggest that this protective effect of capsaicin on OF is du...
journal_title：Indian journal of experimental biology
pub_type： 杂志文章
doi：
更新日期：1999-08-01 00:00:00
abstract：:Study of antitumor and radiosensitizing properties of W. somnifera (Ashwagandha), a well known medicinal plant, have yielded encouraging results. The alcoholic extract of the dried roots of the plant as well as the active component withaferin A isolated from the extract showed significant antitumor and radiosensitizin...
journal_title：Indian journal of experimental biology
pub_type： 杂志文章,评审
doi：
更新日期：1996-10-01 00:00:00
abstract：:Salmonella pathogenesis is a complex phenomenon and a Type III secretion system plays a central role in the development of Salmonella-induced enteritis. One such Type III secretion protein is Salmonella outer protein E (SopE). Prevalence of sopE gene and its phenotypic expression (SopE protein) among different serovar...
journal_title：Indian journal of experimental biology
pub_type： 杂志文章
doi：
更新日期：2005-07-01 00:00:00
abstract：:Administration of rutin (50 and 100 mg/kg) and pioglitazone (10 mg/kg) orally for 3 weeks treatment significantly improved body weight, reduced plasma glucose and glycosylated hemoglobin, pro-inflammatory cytokines (IL-6 and TNF-alpha), restored the depleted liver antioxidant status and serum lipid profile in high fat...
journal_title：Indian journal of experimental biology
pub_type： 杂志文章
doi：
更新日期：2014-07-01 00:00:00
abstract：:Dicarboxylic acids and a few amino acids were found to support mitochondrial phosphorylation in A. ceylanicum. Anaerobiasis markedly reduced this activity. Maximum effect was observed on succinate supported phosphorylation which in anaerobic atmosphere yielded only 2% ATP compared to that in the presence of air. Known...
journal_title：Indian journal of experimental biology
pub_type： 杂志文章
doi：
更新日期：1990-06-01 00:00:00
abstract：:Substance P (SP) injection in the plantar region of rat hind paw caused a dose related inflammation, which reached a peak within 10 min of injection and declined after 60 min. Low doses (0.25-0.063 mg/kg) of SP-antagonists like (D-Pro2, D-Trp7,9)-SP and (D-Pro2, D-Phe7, D-Trp9)-SP pretreatment significantly inhibited ...
journal_title：Indian journal of experimental biology
pub_type： 杂志文章
doi：
更新日期：1990-10-01 00:00:00
abstract：:Realization of hazardious effects of chemical fungicides has led to an interest in the usage of biocontrol agents. The present study, therefore, evaluates the biocontrol efficacy of Western Ghats (India) soil bacterial isolates. A potential strain NII 1006 was evaluated for its antagonistic property against a diverse ...
journal_title：Indian journal of experimental biology
pub_type： 杂志文章
doi：
更新日期：2014-11-01 00:00:00
abstract：:Serum corticosterone excess was induced by the administration of corticosterone acetate to adrenal intact rats. Different lipid classes were studied in unwashed and washed (epididymal sperm and fluid free) caput and cauda epididymides. The unwashed caput epididymidis registered a significant decrease in total lipid, c...
journal_title：Indian journal of experimental biology
pub_type： 杂志文章
doi：
更新日期：1989-08-01 00:00:00
abstract：:Ponderal, histological, and biochemical responses of the uterus, cervix, and vagina to the same dosage (1.5 mg/kg/day for 5 days) of cis- and transclomiphene were studied in ovariectomized rats in the presence and absence of estradiol-dipropionate (EDP). The results indicated that both isomers were estrogenic-cum-an...
journal_title：Indian journal of experimental biology
pub_type： 杂志文章
doi：
更新日期：1973-01-01 00:00:00
abstract：:Intramuscular injection of 3-[p-(N-2-pyrimidylsulfamoyl)phenylhydrazono]pentane-2,4-dio ne (compound I) resulted in decrease in haemoglobin and alanine transaminase (ALT) and increase in aspartate transaminase (AST) values in albino rats. The serum glucose was found to decrease and after administration of 14 doses of ...
journal_title：Indian journal of experimental biology
pub_type： 杂志文章
doi：
更新日期：1996-10-01 00:00:00
abstract：:Light microscopic study of hippocampal sub-regions demonstrated significant number of degenerated nerve cell bodies in the CA3, CA4 and dentate gyrus(Dg) areas of sodium fluoride administered adult female mice. Ultrastructural studies revealed neurodegenrative characteristics like involution of cell membranes, swellin...
journal_title：Indian journal of experimental biology
pub_type： 杂志文章
doi：
更新日期：2002-05-01 00:00:00
abstract：:Diseases like tropical ataxic neuropathy and endemic goitre have been reported to have definite correlation with a chronic ingestion of cassava (Manihot esculenta Crantz). The toxicity of cassava has been attributed to its two cyanogenic glycosides, linamarin and lotaustralin. In this study, an attempt has been made t...
journal_title：Indian journal of experimental biology
pub_type： 杂志文章
doi：
更新日期：1989-06-01 00:00:00
abstract：:Effects of steroid hormones on beta-glucuronidase activities of granulosa cells and theca interstitial cells were studied in vitro in the presence and absence of cholesterol in minimum essential medium (MEM with Hank's salts). Conspicuous fall in the enzyme activities of both these cells were noticed during first 10 m...
journal_title：Indian journal of experimental biology
pub_type： 杂志文章
doi：
更新日期：1995-05-01 00:00:00
abstract：:Administration of tarakeswara rasa--an ayurvedic drug--to alloxan induced diabetic rats resulted in a significant decrease in the blood glucose. Its antidiabetic effect was also evident from the tissue parameters estimated. The drug administration to diabetic rats also resulted in the reduction of cholesterol, triglyc...
journal_title：Indian journal of experimental biology
pub_type： 杂志文章
doi：
更新日期：1997-08-01 00:00:00
abstract：:The effect of the oral administration of megestrol acetate (MA; 17 alpha-acetoxy-6-dehydro-6-methylprogesterone) for 30 days at a dose of 40 mg/kg body weight/day on the genital organs and fertility of male rats was studied. MA had no effect on spermatogenesis or the fertility of the animals. However, the weights of...
journal_title：Indian journal of experimental biology
pub_type： 杂志文章
doi：
更新日期：1965-10-01 00:00:00
abstract：:Using polyclonal antibodies generated against human seminal plasma inhibin (10.5 KDa), immunocytochemical localization was carried out in paraffin embedded tissue sections of human endometrial biopsies obtained at various phases of the menstrual cycle. A positive reaction which indicated the presence of inhibin was ch...
journal_title：Indian journal of experimental biology
pub_type： 杂志文章
doi：
更新日期：1991-10-01 00:00:00
abstract：:The ELISA and GM1-ELISA, by using antiserum to purified Salmonella enterotoxin (SE), were standardized and carried out to screen salmonellae isolated from foods of animal origin for enterotoxigenicity. Of the 101 strains of Salmonella belonging to 15 different serogroups tested, 76 (75.24%) strains from 13 serogroups ...
journal_title：Indian journal of experimental biology
pub_type： 杂志文章
doi：
更新日期：1991-10-01 00:00:00
abstract：:Natural Killer activity assessed by 51Cr release assay from K-562 cells showed detectable activity from 5th day after tumour transplantation, reaching a peak on 12th day and thereafter showing a gradual decline in the activity. Antibody dependent cell mediated cytotoxicity estimated by 51Cr labelled sheep red blood ce...
journal_title：Indian journal of experimental biology
pub_type： 杂志文章
doi：
更新日期：1989-06-01 00:00:00
abstract：:Eclosion rhythm parameters of D. ananassae strains originating between 8 degrees-34 degrees N were highly variable and latitude dependent. In the field under naturally fluctuating light intensity, temperature and R.H., the amplitude of the rhythm was high and the eclosion gate was narrow; however, under the naturally ...
journal_title：Indian journal of experimental biology
pub_type： 杂志文章
doi：
更新日期：1999-07-01 00:00:00
abstract：:Treatment of full-thickness wounds with A. vera, on rats resulted in increased biosynthesis of collagen and its degradation. A corresponding increase in the urinary excretion of hydroxyproline was also observed. Elevated levels of lysyl oxidase also indicated increased crosslinking of newly synthesised collagen. The r...
journal_title：Indian journal of experimental biology
pub_type： 杂志文章
doi：
更新日期：1998-09-01 00:00:00
abstract：:Cyclophosphamide is a potent immunosuppressive agent and is being widely used in organ transplantation. The effects of this anti-rejection drug on lymphoid organs are poorly understood. Newborn Swiss mice injected with various doses of cyclophosphamide suffered from wasting disease at 4 weeks post treatment. The incid...
journal_title：Indian journal of experimental biology
pub_type： 杂志文章
doi：
更新日期：1992-01-01 00:00:00
abstract：:Here, we investigated the quantitative and qualitative differences in antibody classes and subclasses in serum immune complexes (ICs) of Visceral Leishmaniasis (VL), Post Kala-azar Dermal Leishmaniasis (PKDL) and different cross reactive diseases like Malaria, Leprosy, Vitiligo as compared to control subjects. IC leve...
journal_title：Indian journal of experimental biology
pub_type： 杂志文章
doi：
更新日期：2015-06-01 00:00:00
abstract：:Aqueous extract of Andrographis paniculata was examined for antioxidant activity using rat liver subcellular organelles as model systems. The study deals with two important biological oxidative agents, ascorbate-Fe(+2) and AAPH generating hydroxyl and peroxyl radical, respectively. Oxidative damage was examined agains...
journal_title：Indian journal of experimental biology
pub_type： 杂志文章
doi：
更新日期：2007-11-01 00:00:00
abstract：:Mouse melanoma cells were treated with plumbagin, a naphthoquinone, from the plant Plumbago rosea at 0.5 microgram/ml (PI) for 60 min either alone or followed by 2 Gy gamma radiation (RT). Response to the different treatments was assessed by following the cell growth up to 5 days post treatment. PI alone produced a si...
journal_title：Indian journal of experimental biology
pub_type： 杂志文章
doi：
更新日期：1996-09-01 00:00:00
abstract：:Effect of uric acid on sodium oxalate-induced biochemical and histological changes were studied in rats. Rats injected with sodium oxalate (0.7 mg/100 g body wt, ip) show calcium deposits in the lumen of kidney tubules. Uric acid administration was found to potentiate calcium oxalate calculi formation. Lipid peroxide ...
journal_title：Indian journal of experimental biology
pub_type： 杂志文章
doi：
更新日期：1994-01-01 00:00:00
abstract：:Effects of pre- and post-natal undernutrition on learning and memory parameters were studied in albino rats. Prenatal undernutrition was induced in rat pups by restricting the mother's diet by 50% during the entire gestation period, whereas postnatal undernutrition was induced in rat pups by restriction of their diet ...
journal_title：Indian journal of experimental biology
pub_type： 杂志文章
doi：
更新日期：1999-01-01 00:00:00
abstract：:Haloperidol, a butyrophenone used in the treatment of various psychoses has been clinically used and studied extensively. At the molecular level it is known to preferentially block D2 type of dopamine receptors but its other effects are unknown. We studied the effect of this drug on phospholipid biosynthesis in vitro ...
journal_title：Indian journal of experimental biology
pub_type： 杂志文章
doi：
更新日期：1996-02-01 00:00:00
abstract：:Infectious pancreatic necrosis virus (IPNV) from lake trout of Cornwall lake (LT-IPNV), from trout of Jasper (Ja-IPNV) and Arctic char of Northwest Territories (AC-IPNV) are the three isolates recorded from western Canada. Two segments (nt 453-674 and nt 1197-1503) from VP2 coding region of RNA of the isolates were am...
journal_title：Indian journal of experimental biology
pub_type： 杂志文章
doi：
更新日期：1994-08-01 00:00:00
abstract：:Thiram was administered to male rats through gavage at doses 5, 10 and 25 mg/kg/day for 180 and 360 days. Thiram has caused marginal increase in the relative weight of testes and epididymis and decrease in the weight of seminal vesicle and prostate. Marked degenerative changes were observed in seminiferous tubules tog...
journal_title：Indian journal of experimental biology
pub_type： 杂志文章
doi：
更新日期：1998-04-01 00:00:00
