Abstract:
:Using polyclonal antibodies generated against human seminal plasma inhibin (10.5 KDa), immunocytochemical localization was carried out in paraffin embedded tissue sections of human endometrial biopsies obtained at various phases of the menstrual cycle. A positive reaction which indicated the presence of inhibin was characterized by the presence of golden yellow or brown colour in the cytoplasm of epithelial cells that formed the glands as well as the luminal lining. The stromal cells however, showed negative staining. In early proliferative phase, the endometrial glands exhibited weak positive staining for inhibin which gradually increased and was intense in late follicular and early secretory phases. The intensity of the staining although was not diminished in the glandular epithelium in the mid as well as late secretory phases, the number of cells showing positive staining appeared to be reduced. Incubation of endometrial biopsies in vitro with labelled amino acid and immunoprecipitation of newly synthesized protein with specific antibodies to inhibin indicated that endometrium is capable of de novo synthesizing inhibin. The above results suggest that endometrium is an extra ovarian source of inhibin and the possible role of endometrial peptide in sperm fertilizing capabilities as well as in pre and post implantation events is suggested.
journal_name
Indian J Exp Bioljournal_title
Indian journal of experimental biologyauthors
Garde SV,Sheth AR,Zaveri BJ,Shah J,Hinduja Isubject
Has Abstractpub_date
1991-10-01 00:00:00pages
889-96issue
10eissn
0019-5189issn
0975-1009journal_volume
29pub_type
杂志文章abstract::A bioactive compound with antibacterial activity was isolated and purified from the extract of leaves of sunflower, Helianthus annuus. The bioactive compound was characterized using 1H and 13C NMR. The compound induced auxin, gibberellins and cytokinin in Oryza sativa and Phaseolus mungo. It also showed activity again...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:2008-12-01 00:00:00
abstract::The present study has been undertaken to observe the effect of aqueous extract of M. oleifera (MO) leaf (300mg/kg body weight) on mean ulcer index, enterochromaffin (EC) cells and serotonin (5-hydroxytryptamine; 5-HT) content of ulcerated gastric tissue. Ulceration was induced by using aspirin (500 mg/kg, po), cerebel...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:2007-08-01 00:00:00
abstract::Ganoderma lucidum, a white rot fungus, was exploited for its potentials to produce xylanase employing shake and solid-state culture conditions. Different culture conditions such as pH, temperature, carbon and nitrogen requirements for its growth and production of xylanase were optimized. The culture media pH 6.0-7.0 a...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:2003-06-01 00:00:00
abstract::Substance P (SP) and neurotensin (NT), two structurally related peptides with contrasting biological actions, have been shown to have some role in peripheral reproductive processes. Intrauterine microinjection of SP or NT on day 4 or 5 of pregnancy in the rat significantly reduced the number of viable fetuses, weight ...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:1992-02-01 00:00:00
abstract::Osteosarcoma (OSA) is the most common adolescence cancer among all primary bone tumors next only to multiplemyeloma. It has a substantially worse prognosis and ability to metastasize to lung. MMPs (matrix metalloproteinases) are among the major proteases that take part in regulation of ECM (extracellular matrix). MMPs...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:2016-03-01 00:00:00
abstract::The present study evaluates effect of pharmacokinetic interaction between caffeine (300 mg) in three divided doses with sodium valproate (400 mg) and carbamazepine (200 mg) given as single doses, in normal human volunteers, using a open cross over design. Both the serum concentration of sodium valproate and pharmacoki...
journal_title:Indian journal of experimental biology
pub_type: 临床试验,杂志文章
doi:
更新日期:1998-01-01 00:00:00
abstract::The biodegradation of spent saline bottles, a low density polyethylene product (LDPE) by two selected Arthrobacter sp. under in vitro conditions is reported. Chemical and UV pretreatment play a vital role in enhancing the rate of biodegradation. Treated LDPE film exhibits a higher weight loss and density when compared...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:2012-07-01 00:00:00
abstract::The investigations on enzymes related to glutathione like glutathione-S-transferase (GST) and glutathione peroxidase (GSH-Px) have been carried out mostly in human and rat ovaries, however the studies on these enzymes in ruminants are relatively absent. In the present study the changes in the activity of these enzymes...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:2001-11-01 00:00:00
abstract::Convolvulus pluricaulis is an indigenous plant commonly mentioned in Ayurveda, an ancient system of Indian medicine, as a rasayana which is mainly advocated for use in rejuvenation therapy. The present study was conducted to evaluate the potential anti-ulcerogenic effect of juice of fresh whole plants of C. pluricauli...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:2001-04-01 00:00:00
abstract::Serum corticosterone excess was induced by the administration of corticosterone acetate to adrenal intact rats. Different lipid classes were studied in unwashed and washed (epididymal sperm and fluid free) caput and cauda epididymides. The unwashed caput epididymidis registered a significant decrease in total lipid, c...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:1989-08-01 00:00:00
abstract::Studies presented in this paper examined the tumor-specific cellular and humoral immunity induced by anti-idiotype antibodies (Ab2s) 2F10 and 3A4. A panel of Ab2s was made against a monoclonal anti-L1210/GZL lymphoma, 11C1. The Ab2s were screened for their ability to block 11C1 binding to tumor, to induce tumor-specif...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章,评审
doi:
更新日期:1989-08-01 00:00:00
abstract::Abhrak bhasma is a commonly used ayurvedic drug against many diseases including hepatitis. It is tested in albino rats using a model of hepatitis induced by a single dose of CCl4 (3 ml/kg body wt). Different doses of abhrak bhasma (10, 20, 30 and 40 mg/kg body wt) were tested to decide the dose related hepatoprotectiv...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:2001-10-01 00:00:00
abstract::Forty days of orally feeding the aqueous E. ribes extract (100 and 200 mg/kg) to streptozotocin (40 mg/kg, iv, single dose) induced diabetic rats produced significant decrease in heart rate, systolic blood pressure, blood glucose, blood glycosylated hemoglobin, serum lactate dehydrogenase, creatine kinase and increase...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:2008-08-01 00:00:00
abstract::Primary regenerants (1190) of a tall traditional salt tolerant rice cultivar pokkali were produced through in vitro culture from mature seed derived calli of fourth subculture. Out of 35000 SC2 regenerants, 26 promising lines with superior agronomic traits were chosen initially for evaluation. SC3 and SC4 generations ...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:2000-01-01 00:00:00
abstract::Haloperidol, a butyrophenone used in the treatment of various psychoses has been clinically used and studied extensively. At the molecular level it is known to preferentially block D2 type of dopamine receptors but its other effects are unknown. We studied the effect of this drug on phospholipid biosynthesis in vitro ...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:1996-02-01 00:00:00
abstract::Several varieties of peptone supported growth of A. culbertsoni to different extents reaching a maximum cell density of 1-2 X 10(6)/ml. Proteose peptone and tryptone also yielded good growth when combined with thiamine and vitamin B12. A combination of proteose peptone with glucose, yeast extract and salts promoted ex...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:1989-09-01 00:00:00
abstract::Cyclooxygenase (COX) isoenzyme is known to play an important role in the pathophysiology of Parkinson's disease. The present study evaluated the neuroprotective effect of nimesulide, a preferential COX-2-inhibitor against 1-methyl-4-phenyl-1,2,3,6-tertahydropyridine (MPTP)-model of Parkinson's disease. Intrastriatal a...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:2010-06-01 00:00:00
abstract::Effects of multiple weekly (20, 40 and 80 mg/kg) and daily therapeutic (2, 4 and 8 mg/kg) ip doses of C. colebrookianum leaf extract on liver and kidney functions and hematological parameters in mice were studied. No alteration in hematological and biochemical parameters at low and moderate dose level of daily and low...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:1994-03-01 00:00:00
abstract::Here, we investigated the quantitative and qualitative differences in antibody classes and subclasses in serum immune complexes (ICs) of Visceral Leishmaniasis (VL), Post Kala-azar Dermal Leishmaniasis (PKDL) and different cross reactive diseases like Malaria, Leprosy, Vitiligo as compared to control subjects. IC leve...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:2015-06-01 00:00:00
abstract::Skin and tendon samples of male albino rat taken for analysis, on the 120th day of smoking showed that, compared to controls, the cigarette smoke exposed group showed an increase in tensile strength of both skin and tendon while extensibility of skin remained the same and that of the tendon increased. Thermal behaviou...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:1997-07-01 00:00:00
abstract::Administration of CCl4 to normal rats and consequent oral feeding with ellagic acid (50 mg/kg) provided a significant protection against the biochemical alterations in serum and liver produced by CCl4. In vitro experiments showed that liver microsomes from animals treated with ellagic acid and CCl4, decreased lipid pe...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:1999-10-01 00:00:00
abstract::Cognitive disorders in mankind are not uncommon. Apart from neurodegenerative diseases such as Alzheimer's (AD), various stresses also affect cognitive functions. Plants are known to be potential source of compounds that ameliorate several diseases including cognitive impairment. Here, we evaluated effect of aqueous e...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:2016-02-01 00:00:00
abstract::Breast cancer susceptibility gene (BRCA1) is known to be responsible for hereditary breast and ovarian cancer. This gene is highly penetrant conferring a risk for 0.92 by the age of 70. Germline mutation in this gene leads to susceptibility to breast and ovarian cancer, with a genotype phenotype correlation. Frequency...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章,评审
doi:
更新日期:2001-05-01 00:00:00
abstract::Crayfish exoskeleton (CE) samples are generally less invasive and easy to be collected. However, it is difficult to extract DNA from them. This study was intended to investigate CE as a DNA source and design an easy and efficient DNA extraction protocol for polymerase chain reactions. Specific primer pair (PPO-F, PPO-...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:2011-12-01 00:00:00
abstract::A protocol has been devised for enhanced in vitro regeneration of critically endangered Mantisia spathulata Schult. and Mantisia wengeri Fischer. Highest Bud Forming Capacity (BFC) of 6.10 +/- 0.55 with an average of 19.93 +/- 3.19 roots was obtained for M. spathulata within 5-6 weeks in Murashige and Skoogs (MS) medi...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:2009-02-01 00:00:00
abstract::The present study deals with the effect of butylated hydroxy anisole, propyl gallate and alpha-tocopherol on ATPase activity of brain and heart in ageing male mice. The activity of both the tissues significantly increased during pre-reproductive and reproductive phases. However, during the post-reproductive phase, ATP...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:1992-04-01 00:00:00
abstract::The frequency and types of acrocentric chromosome association were quantitatively analysed in a Down syndrome child with unusual karyotype, 46, XX, -14, -22, t dic (14p;22p), +21, 21S+. Father and 4 sibs were heterozygous carriers for t dic (14p;22p). The variant 21S+ was inherited from the mother. The occurrence of t...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:1990-06-01 00:00:00
abstract::Cells and organisms exposed to detrimental and toxic substances show different responses in photon emission dependent on amount, kind and exposure time of toxin as well as on the organism investigated. Radical reaction-generating substances and dehydrating, lipid dissolving and protein denaturating toxins which do not...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:2003-05-01 00:00:00
abstract::Understanding the biochemical and molecular basis of drought mechanism in rice is important as drought is one of the major causes affecting rice crop adversely. A 1017 bp gene sequence encoding AP2/ERF family TF was isolated from Oryza sativa sp. Indica cv N22 encoding a protein of 338 amino acid residues, with a mole...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:2016-01-01 00:00:00
abstract::Paired samples of serum and hydrocele fluid of filarial patients associated with hydrocele were analysed for filarial antibody and antigen. Sera samples showed higher titers of filarial antibody and antigen compared to their corresponding hydrocele fluid samples. HFIgG isolated from hydrocele fluid was equally useful ...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:1993-01-01 00:00:00