Abstract：
:Salmonella pathogenesis is a complex phenomenon and a Type III secretion system plays a central role in the development of Salmonella-induced enteritis. One such Type III secretion protein is Salmonella outer protein E (SopE). Prevalence of sopE gene and its phenotypic expression (SopE protein) among different serovars of Salmonella enterica isolated from man and animals were investigated. Of 305 strains of S. enterica belonging to 11 serovars tested for the presence of sopE, 130 strains belonging to three serovars viz., Enteritidis, Gallinarum and Virchow were found to carry sopE gene irrespective of their source of isolation when tested by PCR amplification technique using its specific primers. Of these 130 strains, 112 strains were found to express SopE protein phenotypically as detected by Dot-ELISA using SopE antibody. Among the different serovars tested only serovars Gallinarum, Enteritidis and Virchow expressed SopE protein phenotypically in vitro. Role of SopE protein in pathogenesis of salmonellosis has been discussed.
journal_name
Indian J Exp Bioljournal_title
Indian journal of experimental biologyauthors
Rahman H,Hardt WD,Murugkar HV,Bhattacharyya DKkeywords:
subject
Has Abstractpub_date
2005-07-01 00:00:00pages
631-4issue
7eissn
0019-5189issn
0975-1009journal_volume
43pub_type
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doi：
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journal_title：Indian journal of experimental biology
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journal_title：Indian journal of experimental biology
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journal_title：Indian journal of experimental biology
pub_type： 杂志文章
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journal_title：Indian journal of experimental biology
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journal_title：Indian journal of experimental biology
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doi：
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journal_title：Indian journal of experimental biology
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doi：
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journal_title：Indian journal of experimental biology
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journal_title：Indian journal of experimental biology
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journal_title：Indian journal of experimental biology
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