Effectiveness of ethylene glycol bis (2-aminoethyl ether) tetraacetic acid (EGTA) against cerium toxicity.

Abstract:

:Therapeutic efficacy of EGTA (ethylene glycol bis (2-aminoethyl ether) tetraacetic acid) against cerium intoxicated mice was studied. Administration of cerium showed significant decrease in haemoglobin percentage, RBC counts and blood glucose level with an increase in the activity of serum transaminases and WBC counts. Decrease in the activity of alkaline phosphatase and glycogen content was noted in liver and kidney after cerium exposure. Light and electron microscopical investigations showed that these changes were recouped considerably with the administration of EGTA suggesting its therapeutic efficacy against cerium toxicity.

journal_name

Indian J Exp Biol

authors

Shrivastava S,Mathur R

keywords:

subject

Has Abstract

pub_date

2004-09-01 00:00:00

pages

876-83

issue

9

eissn

0019-5189

issn

0975-1009

journal_volume

42

pub_type

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