Abstract:
:Five sheep were intoxicated with powdered L. camara, leaves at the rate of 200 mg/kg body weight daily for 110 days and another group of four sheep were drenched with distilled water daily for equal number of days which acted as control. The cell mediated immunity of intoxicated and control sheep was assessed with the help of 2,4-dinitrofluorobenzene skin sensitivity test and graft-versus-host reaction and the antibody forming potential of both the groups of animals was measured by haemagglutination against chicken red blood cells antigen. In addition, the phagocytic activity of splenic reticulo-endothelial cells was analysed by nitro blue tetrazolium test. The results indicated significant reduction of both cellular and humoral immunity due to L. camara toxicity. The non-specific phagocytic activity of splenic reticulo-endothelial cells also showed significant reduction due to L. camara, L. intoxication. The present communication constitutes the first report of in vivo immunosuppression due to chronic lantana poisoning in sheep.
journal_name
Indian J Exp Bioljournal_title
Indian journal of experimental biologyauthors
Ganai GN,Jha GJsubject
Has Abstractpub_date
1991-08-01 00:00:00pages
762-6issue
8eissn
0019-5189issn
0975-1009journal_volume
29pub_type
杂志文章abstract::The present study revealed the damaging effects of copper and hydrogen peroxide on DNA isolated from human blood in in vitro. Ultra violet spectral studies showed that copper and H2O2 alone (at 20 mM) caused destabilization of DNA structure. Notwithstanding, the effect was more prominent in combination of copper and H...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:2006-05-01 00:00:00
abstract::Urokinase-type plasminogen activator(uPA) assayed in uteri of cycling and deciduoma bearing rats shows detectable levels of this enzyme in endometrium. Zymographic analysis confirms uPA of decidual tissue and, following artificial induction of decidualisation, uPA activity constantly increases in the decidualising end...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:1994-05-01 00:00:00
abstract::BC-8, a rat histiocytoma undergoes apoptosis after heat shock, which is due to lack of an effective heat shock response. Heat shock induced generation of free radicals, which in turn are involved in the induction of apoptotic death in BC-8 cells. Treatment of BC-8 cells with N-acetylcysteine partially inhibited the he...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:2006-10-01 00:00:00
abstract::Prostatic diseases affect men over the age of 45 and increase in frequency with age so that by the eighth decade more than 90% of men have Benign Prostatic Hyperplasia, (BPH), of which some progress to Carcinoma of Prostate (CaP). CaP, the most common malignancy in men, is also the second most common cause of death in...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章,评审
doi:
更新日期:1999-07-01 00:00:00
abstract::An investigation for testing the viability of production of cloned buffalo embryos through nucleus transfer has been made. Matured buffalo oocytes, after zona cutting to an extent of 60 degrees near polar body, were enucleated using a new approach. Instead of aspirating the cytoplasm contents in a pipette, the half of...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:1997-12-01 00:00:00
abstract::Concentrations of mono- and divalent cations in the testis, three different regions of the epididymis and the vas deferens of lizard, M. carinata were determined. The concentrations of Na+, K+ and Ca2+ increased gradually from testis to vas deferens. However, no significant variation in the levels of Mg2+ was observed...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:2008-10-01 00:00:00
abstract::The whole seed extract of S. nux vomica (in low doses) effectively neutralized Daboia russelii venom induced lethal, haemorrhage, defibrinogenating, PLA2 enzyme activity and Naja kaouthia venom induced lethal, cardiotoxic, neurotoxic, PLA2 enzyme activity. The seed extract potentiated polyvalent snake venom antiserum ...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:2004-05-01 00:00:00
abstract::Initially a dose-response curve of phenylephrine was constructed at dose strengths of 1-16 microg/kg in a cumulative manner. Phenylephrine caused a significant rise in the mean arterial pressure, left ventricular systolic pressure, left ventricular contractility, stroke volume and a significant decline in the heart ra...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:2004-12-01 00:00:00
abstract::Parkinson's disease (PD) is a neurodegenerative disease characterized by the selective loss of dopamine (DA) neurons of the substantia nigra pars compacta (SNc). The events, which trigger and/or mediate the loss of nigral DA neurons, however, remain unclear. Neuroleptic-induced catalepsy has long been used as an anima...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:2006-01-01 00:00:00
abstract::Adult mice weighing 20 g, divided into 5 groups, were immunised with single and three cycle cryodestroyed ascites fibrosarcoma cells using different modes of immunisation with respect to dose and administration frequency. Survival against subsequent challenge with the same tumour cells and immune response given by leu...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:1990-11-01 00:00:00
abstract::The present study was undertaken to evaluate the role of propofol in altering pentylenetetrazol induced seizure threshold in rats. Total 42 Wistar rats were used to evaluate different parameters (onset of action, duration of seizure, seizure severity score and number of seizure) following propofol injection. The prese...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:2008-03-01 00:00:00
abstract::Enzyme levels of serum glutamate oxaloacetate transaminase (SGOT), serum glutamate pyruvate transaminase (SGPT) and alkaline phosphatase (ALP) increased following paracetamol induction were significantly lowered due to pretreatment with the beta-carotene (BC). This supplementation reversed the trend inducing a signifi...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:2005-04-01 00:00:00
abstract::Administration of testosterone propionate (TP; 1 mg/kg body weight/day; im, for 30 days) to mature male bonnet monkeys, decreased total lipids, glyceride glycerol and cholesterol concentrations in hepatic tissue. The decrease in glyceride glycerol was due to decrease in monoacyl and triacyl glycerol. Both, free and es...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:1991-12-01 00:00:00
abstract::Aqueous extract of leaves of M. oleifera was investigated and rationalised for its wound healing activity. The aqueous extract was studied at dose level of 300 mg/kg body weight using resutured incision; excision and dead space wound models in rats. Significant increase in wound closure rate, skin-breaking strength, g...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:2006-11-01 00:00:00
abstract::Progesterone, primarily recognized as a female steroid hormone, is reported to affect several sperm functions especially capacitation, motility and acrosome reaction. These effects of progesterone on the spermatozoa are mediated via the progesterone binding sites/progesterone receptor (PR) on the acrosomal membrane. T...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章,评审
doi:
更新日期:2003-07-01 00:00:00
abstract::Anabas testudineus (2n = 46) had the more conserved pattern of its C-heterochromatin distributed mainly in the centromeric region, whereas Puntius sarana (2n = 50) exhibited a rather unorthodox pattern, many chromosomes showing interstitial, some telomeric and a few chromosomes showing centromeric C-band localization....
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:2000-03-01 00:00:00
abstract::A strain of T. chilonis, an egg parasitoid of lepidopteran pests tolerant to the most commonly used cyclodiene insecticide--endosulfan was developed in the laboratory. Tolerance to endosulfan was induced by exposing adult parasitoids sequentially from a sub-lethal concentration (0.004%) to the field recommended concen...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:2006-07-01 00:00:00
abstract::"Triphala", the Ayurvedic wonder is used traditionally for the treatment of different types of diseases since antiquity. The hydroalcoholic extracts of the three components of Triphala powder demonstrated varying degrees of strain specific antibacterial activity against multidrug-resistant uropathogenic bacteria. Term...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:2013-09-01 00:00:00
abstract::The neutral detergent fiber (NDF) isolated from coconut kernel was digested with cellulase and hemicellulase and the residual fiber rich in hemicellulose (without cellulose) and cellulose (with out hemicellulose) were fed to rats and compared with a fiber free group. The results indicate that hemicellulose rich fiber ...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:1998-08-01 00:00:00
abstract::Germ cell death and their removal from the seminiferous epithelium are common in the affected testis in conditions of unilateral ischemia or cryptorchidism; the similarities and differences, however, have not been studied between these two conditions. The present study was designed to examine the severity of the effec...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:2005-11-01 00:00:00
abstract::Capsaicin exerts a stabilizing effect on erythrocytes making them more resistant to lysis under hypotonic stress. The protective action of capsaicin on osmotic fragility (OF) was not receptor mediated since no dose responsive effect was observed. The results suggest that this protective effect of capsaicin on OF is du...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:1999-08-01 00:00:00
abstract::Reduction of p-benzoquinone to hydroquinol has been studied using Saccharomyces cerevisae and S.uvarum. Maximum conversion of p-Benzoquinone (p-BQ) to Hydroquinol (HQ) at a substrate concentration of 6%. S. cerevisae was found to be better than S. uvarum. No further conversion did take place after 60 hr. Optical innoc...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:1995-01-01 00:00:00
abstract::Blood samples of malaria patients (n = 30), selected based on the severity of parasitemia, were divided into low (LP), medium (MP) and high (HP) parasitemia, which represent increasing levels of the disease severity. Healthy subjects (n = 10) without any history of disease were selected as a control group. By processi...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:2011-01-01 00:00:00
abstract::Therapeutic efficacy of EGTA (ethylene glycol bis (2-aminoethyl ether) tetraacetic acid) against cerium intoxicated mice was studied. Administration of cerium showed significant decrease in haemoglobin percentage, RBC counts and blood glucose level with an increase in the activity of serum transaminases and WBC counts...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:2004-09-01 00:00:00
abstract::The effects of dopamine (DA) agonists and antagonists were investigated on indomethacin--and restraint stress (6 hr at RT)--induced gastric ulcer formation in rats. The DA-agonists, apomorphine and bromocryptine (both at 5 mg/kg) significantly attenuated the frequency and severity of gastric mucosal lesions in both ex...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:1990-06-01 00:00:00
abstract::Cisplatin-based chemotherapy has a variety of vascular side effects. The aim of the present study was to evaluate the beneficial effect of melatonin and cisplatin on the alterations in vascular reactivity and structure of cisplatin-treated rats. Phenylephrine (PHE) and KCl-caused concentration-dependent contractions o...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:2010-12-01 00:00:00
abstract::Rats pre-administered with alpha-tocopherol (10 mgs/day) for 7 days afforded a significant protection at the tissue level against the lowering of superoxide dismutase and glutathione peroxidase, especially the selenium-dependent glutathione peroxidase. The protective action of alpha-tocopherol in the diethyldithiocarb...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:2007-05-01 00:00:00
abstract::The whole plant aqueous extract of E. littorale was tested for its hypoglycemic activity on normoglycemic, hyperglycemic and alloxan induced diabetic rats. Blood sugar lowering activity was not observed in normoglycemic and glucose loaded hyperglycemic rats in the short time experiment. But in case of diabetic rats, t...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:2000-08-01 00:00:00
abstract::Infectious pancreatic necrosis virus (IPNV) from lake trout of Cornwall lake (LT-IPNV), from trout of Jasper (Ja-IPNV) and Arctic char of Northwest Territories (AC-IPNV) are the three isolates recorded from western Canada. Two segments (nt 453-674 and nt 1197-1503) from VP2 coding region of RNA of the isolates were am...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:1994-08-01 00:00:00
abstract::Estradiol-17beta (E2) at the dose of 1 microg/g caused an increase in cell area, lumen area and the total (cell + lumen) area of posterior silk gland (PSG) in Bombyx mori indicating that exogenously applied estradiol-17beta has a regulatory influence on silk gland activity. A dose-dependent variation in trehalase acti...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:2001-11-01 00:00:00