Abstract:
:Blood samples of malaria patients (n = 30), selected based on the severity of parasitemia, were divided into low (LP), medium (MP) and high (HP) parasitemia, which represent increasing levels of the disease severity. Healthy subjects (n = 10) without any history of disease were selected as a control group. By processing of erythrocytes images their contours were obtained and from these the shape parameters area, perimeter and form factor were obtained. The gray level intensity was determined by scanning of erythrocyte along its largest diameter. A comparison of these with that of normal cells showed a significant change in shape parameters. The gray level intensity decreases with the increase of severity of the disease. The changes in shape parameters directly and gray level intensity variation inversely are correlated with the increase in parasite density due to the disease.
journal_name
Indian J Exp Bioljournal_title
Indian journal of experimental biologyauthors
Edison M,Jeeva JB,Singh Msubject
Has Abstractpub_date
2011-01-01 00:00:00pages
11-5issue
1eissn
0019-5189issn
0975-1009journal_volume
49pub_type
杂志文章abstract::There was a significant increase in fucose (52%), total hexoses (16%) and hexosamine (56%) except sialic acid, which was reduced (77%) in the microvillus membrane of infants born to rat mothers made diabetic by injecting alloxan on day 3 of gestation. Expressed on the protein basis there were a significant increase in...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:2012-01-01 00:00:00
abstract::Treatment of full-thickness wounds with A. vera, on rats resulted in increased biosynthesis of collagen and its degradation. A corresponding increase in the urinary excretion of hydroxyproline was also observed. Elevated levels of lysyl oxidase also indicated increased crosslinking of newly synthesised collagen. The r...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:1998-09-01 00:00:00
abstract::The present study evaluates effect of pharmacokinetic interaction between caffeine (300 mg) in three divided doses with sodium valproate (400 mg) and carbamazepine (200 mg) given as single doses, in normal human volunteers, using a open cross over design. Both the serum concentration of sodium valproate and pharmacoki...
journal_title:Indian journal of experimental biology
pub_type: 临床试验,杂志文章
doi:
更新日期:1998-01-01 00:00:00
abstract::The in vitro percutaneous absorption of verapamil hydrochloride (VHCl) was investigated in order to assess its feasibility for transdermal development. The experiments were carried across mice and guinea pig skins using Keshary-Chien diffusion cell. The values of diffusion rate (J) and permeability coefficient (Kp) ac...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:1996-05-01 00:00:00
abstract::Antiperoxidative property of N. jatamanasi was tested by using iron induced lipid peroxidation in 5% rat liver homogenate. The degree of peroxidation was quantitated by thiobarbituric acid reactive substance (TBARS) content. The extract provided protection against lipid peroxidation. The hexane fraction was more poten...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:1996-11-01 00:00:00
abstract::Role of fatty acid binding proteins (FABPs) in modulating inhibition of human placental malate dehydrogenase by palmitoyl-CoA and oleate has been studied. Activity of human placental cytosolic malate dehydrogenase is detected throughout the gestation, showing a peak at midgestation (20-25 weeks). Inhibition (50%) of t...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:1994-11-01 00:00:00
abstract::Mast cell dynamics has been studied in relation to cystogenesis of ovarian follicles in the house rat. Immature rats were injected (s.c.) daily with DHEA (6.0 mg/100 g body weight) and were sacrificed on the day 8, 16 and 24 of the start of treatment. Ovarian sections of the treated rats had majority of the antral fol...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:1999-09-01 00:00:00
abstract::Parkinson's disease (PD) is a neurodegenerative disease characterized by the selective loss of dopamine (DA) neurons of the substantia nigra pars compacta (SNc). The events, which trigger and/or mediate the loss of nigral DA neurons, however, remain unclear. Neuroleptic-induced catalepsy has long been used as an anima...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:2006-01-01 00:00:00
abstract::Administration of testosterone propionate (TP; 1 mg/kg body weight/day; im, for 30 days) to mature male bonnet monkeys, decreased total lipids, glyceride glycerol and cholesterol concentrations in hepatic tissue. The decrease in glyceride glycerol was due to decrease in monoacyl and triacyl glycerol. Both, free and es...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:1991-12-01 00:00:00
abstract::A rationale of arriving at the concentration of surfactant additives in the pesticidal formulations has been discovered. Fungitoxic activity of each of the two dithanes, Dithane M-45 (maneb) and Dithane Z-78 (zineb) has been estimated in the presence of various concentrations of three surfactants namely sodium lauryl ...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:1996-04-01 00:00:00
abstract::Formulations (ointment, cream and gel) of aqueous extract of C. asiatica, when applied topically, thrice daily for 24 days on the open wounds in rats increased cellular proliferation and collagen synthesis at the wound site, as evidenced by increase in collagen content and tensile strength. The treated wounds epitheli...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:1998-06-01 00:00:00
abstract::Three lipophilic amide derivatives of phthaloyl-GABA (P-GABA), namely gamma-phthalimido N-amyl butyramide (PGA), gamma-phthalimido-N-hexylbutyramide (PGH) and gamma-phthalimido N-phenylbutyramide (PGP), were synthesized and evaluated for their hypnotic and anticonvulsant activities in mice. Both PGA and PGH showed mod...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:1992-07-01 00:00:00
abstract::Multiple doses of H. spinosa were administered, ip once in a week for 4 weeks (20, 40 and 80 mg/kg body weight) and daily for one month (2, 4 and 8 mg/kg body weight). No alteration in biochemical parameters at low and moderate dose level of daily and low dose level of weekly treatment of petroleum ether extract was o...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:1996-12-01 00:00:00
abstract::Bryan Standard strain of Rous Sarcoma Virus (BS-RSV) of subgroup A and pseudotype of Bryan high titre RSV(RAV-49) of subgroup C and an equal mixture of subgroup A and subgroup C virus were inoculated to 11-day old embryos of white leghorn (WL), Australorp (AL) and f1 and f2 generations of crosses between WL and AL bre...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:1997-01-01 00:00:00
abstract::Reperfusion injury is remarkable clinical issue that needs to be resolved as ischemia-reperfusion is a common phenomenon encountered in numerous clinical situations. The present communication report the involvement of nitric oxide (NO) in cardioprotection offered by flavonoids (rutin and quercetin) against myocardial ...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:2011-03-01 00:00:00
abstract::Antioxidant role of Arogh in isoproterenol induced myocardial infarction in rats has been studied. The activity of heart tissue antioxidants like glutathione, superoxide dismutase, catalase, glutathione peroxidase and glutathione-s-transferase were significantly decreased in isoproterenol administered group. The activ...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:2004-02-01 00:00:00
abstract::Considering the lipophilicity of aspirin (log P = -1.15), a significant contributor to its action mechanism, interaction of the drug with the whole lipids of goat blood have been investigated using phospholipid binding and lipid peroxidation phenomena as the parameters under investigation. The lipid content change alo...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:2000-09-01 00:00:00
abstract::Pregnant Swiss albino mice were exposed to diagnostic ultrasound (3.5 MHz, 65mw, ISPTP = 1 W/cm2, ISATA = 240 W/cm2) for 10 min on day 14, 16 or 17 of gestation to assess any changes in physiological reflexes (pinna detachment, eye opening and fur development) and postnatal mortality. Changes in locomotor activity by ...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:1996-09-01 00:00:00
abstract::Effect of electrolytic lesion in vestibulo-cerebellar area of male Wistar rats was investigated on duodenal alkaline phosphatase (AP) activity. Histomorphological observations of brain indicated, that extensive lesion restricted to the wide area of nodule including ventral uvula, resulted in significant fall of AP act...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:1995-10-01 00:00:00
abstract::Lipopolysaccharide (LPS) and ratio-detoxified LPS (Rd-LPS) from Salmonella typhimurium were analysed for their ability to stimulate murine peritoneal exudate cells (PEC) and macrophages. Rd-LPS induced much more inflammatory response as compared to LPS. PEC numbers/mouse obtained were significantly higher (3-fold) in ...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:1999-03-01 00:00:00
abstract::Effect of oral feeding of Liv-52, on lipid peroxidation in normal liver and damaged liver induced by CCl4 of albino rats was studied. While Liv-52 did not show any effect on normal healthy liver cells, it had a significant protective effect against damage by CCl4 as shown by significant decrease in malonaldialdehyde c...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:1994-09-01 00:00:00
abstract::Detached inflorescences of guar (Cyamopsis tetragonoloba), each bearing 4 uniformly-developing pods at 42 days post anthesis (DPA), were cultured for 6 days in complete liquid medium manipulated with a fixed concentration of mannose and varying concentration of myo-inositol. Such inflorescences, but with 2 pods, were ...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:2000-06-01 00:00:00
abstract::Sulforaphane, a constituent of broccoli was investigated for its antimutagenic potential against different classes of cooked food mutagens (heterocyclic amines). These include imidazoazaarenes such as 2-amino-3-methylimidazo[4,5-f]quinoline (IQ), 2-amino-3,4-dimethylimidazo[4,5-f]quinoline (MeIQ), 2-amino-3,8-dimethyl...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:2003-03-01 00:00:00
abstract::Toxic bait discs were prepared by incorporating the larvicide Abate (Temephos) technical, with yeast and dog biscuit (1:1), the latter forming the attractant source. These were assessed in 1, 10 and 25 litre aquaria and 100 litre drums against Aedes aegypti larvae. Floating as well as sinking bait discs were found equ...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:1996-03-01 00:00:00
abstract::Effects of a selective monoamine oxidase (MAO)--A inhibitor, clorgyline, a selective MAO-B inhibitor, deprenyl, and a non-selective MAO inhibitor, nialamide, were investigated on footshock-induced aggression (FIA) in paired rats. The doses and pretreatment times of the inhibitors used were based on an earlier reported...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:1990-08-01 00:00:00
abstract::Fissioncytorace-1, a member of the nasuta-albomicans complex of Drosophila is an evolutionary product of centric fission, which had occurred in the chromosome X3 of Cytorace 1, a hydridization product of Drosophila nasuta nasuta male (2n=8) and Drosophila nasuta albomicans female (2n=6). Cytorace 1 (males 2n=7; female...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:2010-05-01 00:00:00
abstract::Drought stress is one of the major factors affecting nitrogen fixation by legume-rhizobium symbiosis. Several mechanisms have been previously reported to be involved in the physiological response of symbiotic nitrogen fixation to drought stress, i.e. carbon shortage and nodule carbon metabolism, oxygen limitation, and...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章,评审
doi:
更新日期:2003-10-01 00:00:00
abstract::The present study was undertaken to investigate the in vitro influence of mibefradil, a calcium channel blocker, and pinacidil, a potassium channel opener, on pregnant goat myometrial spontaneous rhythmic contractility and contractions induced with the agonist, oxytocin. Longitudinal strips from the distal region of u...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:2005-09-01 00:00:00
abstract::Reduction of p-benzoquinone to hydroquinol has been studied using Saccharomyces cerevisae and S.uvarum. Maximum conversion of p-Benzoquinone (p-BQ) to Hydroquinol (HQ) at a substrate concentration of 6%. S. cerevisae was found to be better than S. uvarum. No further conversion did take place after 60 hr. Optical innoc...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:1995-01-01 00:00:00
abstract::Cognitive disorders in mankind are not uncommon. Apart from neurodegenerative diseases such as Alzheimer's (AD), various stresses also affect cognitive functions. Plants are known to be potential source of compounds that ameliorate several diseases including cognitive impairment. Here, we evaluated effect of aqueous e...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:2016-02-01 00:00:00