Digital analysis of changes by Plasmodium vivax malaria in erythrocytes.

Abstract:

:Blood samples of malaria patients (n = 30), selected based on the severity of parasitemia, were divided into low (LP), medium (MP) and high (HP) parasitemia, which represent increasing levels of the disease severity. Healthy subjects (n = 10) without any history of disease were selected as a control group. By processing of erythrocytes images their contours were obtained and from these the shape parameters area, perimeter and form factor were obtained. The gray level intensity was determined by scanning of erythrocyte along its largest diameter. A comparison of these with that of normal cells showed a significant change in shape parameters. The gray level intensity decreases with the increase of severity of the disease. The changes in shape parameters directly and gray level intensity variation inversely are correlated with the increase in parasite density due to the disease.

journal_name

Indian J Exp Biol

authors

Edison M,Jeeva JB,Singh M

subject

Has Abstract

pub_date

2011-01-01 00:00:00

pages

11-5

issue

1

eissn

0019-5189

issn

0975-1009

journal_volume

49

pub_type

杂志文章
  • Modulation of intestinal brush border membrane chemical composition during postnatal development in rats: effect of gestational diabetes.

    abstract::There was a significant increase in fucose (52%), total hexoses (16%) and hexosamine (56%) except sialic acid, which was reduced (77%) in the microvillus membrane of infants born to rat mothers made diabetic by injecting alloxan on day 3 of gestation. Expressed on the protein basis there were a significant increase in...

    journal_title:Indian journal of experimental biology

    pub_type: 杂志文章

    doi:

    authors: Sharma R,Chauhan SS,Mahmood A

    更新日期:2012-01-01 00:00:00

  • Influence of Aloe vera on collagen turnover in healing of dermal wounds in rats.

    abstract::Treatment of full-thickness wounds with A. vera, on rats resulted in increased biosynthesis of collagen and its degradation. A corresponding increase in the urinary excretion of hydroxyproline was also observed. Elevated levels of lysyl oxidase also indicated increased crosslinking of newly synthesised collagen. The r...

    journal_title:Indian journal of experimental biology

    pub_type: 杂志文章

    doi:

    authors: Chithra P,Sajithlal GB,Chandrakasan G

    更新日期:1998-09-01 00:00:00

  • Influence of caffeine on pharmacokinetic profile of sodium valproate and carbamazepine in normal human volunteers.

    abstract::The present study evaluates effect of pharmacokinetic interaction between caffeine (300 mg) in three divided doses with sodium valproate (400 mg) and carbamazepine (200 mg) given as single doses, in normal human volunteers, using a open cross over design. Both the serum concentration of sodium valproate and pharmacoki...

    journal_title:Indian journal of experimental biology

    pub_type: 临床试验,杂志文章

    doi:

    authors: Vaz J,Kulkarni C,David J,Joseph T

    更新日期:1998-01-01 00:00:00

  • In vitro percutaneous absorption of verapamil.

    abstract::The in vitro percutaneous absorption of verapamil hydrochloride (VHCl) was investigated in order to assess its feasibility for transdermal development. The experiments were carried across mice and guinea pig skins using Keshary-Chien diffusion cell. The values of diffusion rate (J) and permeability coefficient (Kp) ac...

    journal_title:Indian journal of experimental biology

    pub_type: 杂志文章

    doi:

    authors: Jain GK,Agrawal SS

    更新日期:1996-05-01 00:00:00

  • Antilipid peroxidative property of Nardostachys jatamanasi.

    abstract::Antiperoxidative property of N. jatamanasi was tested by using iron induced lipid peroxidation in 5% rat liver homogenate. The degree of peroxidation was quantitated by thiobarbituric acid reactive substance (TBARS) content. The extract provided protection against lipid peroxidation. The hexane fraction was more poten...

    journal_title:Indian journal of experimental biology

    pub_type: 杂志文章

    doi:

    authors: Tripathi YB,Tripathi E,Upadhyay A

    更新日期:1996-11-01 00:00:00

  • Effect of fatty acid binding proteins on developing human placental malate dehydrogenase activity.

    abstract::Role of fatty acid binding proteins (FABPs) in modulating inhibition of human placental malate dehydrogenase by palmitoyl-CoA and oleate has been studied. Activity of human placental cytosolic malate dehydrogenase is detected throughout the gestation, showing a peak at midgestation (20-25 weeks). Inhibition (50%) of t...

    journal_title:Indian journal of experimental biology

    pub_type: 杂志文章

    doi:

    authors: Bandyopadhyay AK,Das T,Sa G,Mukherjea M

    更新日期:1994-11-01 00:00:00

  • Cystogenesis of antral follicles induced by dehydroepiandrosterone (DHEA) stimulates mast cell proliferation and maturation in the house rat (Rattus rattus) ovary.

    abstract::Mast cell dynamics has been studied in relation to cystogenesis of ovarian follicles in the house rat. Immature rats were injected (s.c.) daily with DHEA (6.0 mg/100 g body weight) and were sacrificed on the day 8, 16 and 24 of the start of treatment. Ovarian sections of the treated rats had majority of the antral fol...

    journal_title:Indian journal of experimental biology

    pub_type: 杂志文章

    doi:

    authors: Parshad RK,Batth BK

    更新日期:1999-09-01 00:00:00

  • Effect of BR-16A (Mentat), a polyherbal formulation on drug-induced catalepsy in mice.

    abstract::Parkinson's disease (PD) is a neurodegenerative disease characterized by the selective loss of dopamine (DA) neurons of the substantia nigra pars compacta (SNc). The events, which trigger and/or mediate the loss of nigral DA neurons, however, remain unclear. Neuroleptic-induced catalepsy has long been used as an anima...

    journal_title:Indian journal of experimental biology

    pub_type: 杂志文章

    doi:

    authors: Kumar A,Kulkarni SK

    更新日期:2006-01-01 00:00:00

  • Relationship between testosterone and hepatic lipids in mature male bonnet monkeys, Macaca radiata (Geoffroy).

    abstract::Administration of testosterone propionate (TP; 1 mg/kg body weight/day; im, for 30 days) to mature male bonnet monkeys, decreased total lipids, glyceride glycerol and cholesterol concentrations in hepatic tissue. The decrease in glyceride glycerol was due to decrease in monoacyl and triacyl glycerol. Both, free and es...

    journal_title:Indian journal of experimental biology

    pub_type: 杂志文章

    doi:

    authors: Jeyaraj DA,Govindarajulu P

    更新日期:1991-12-01 00:00:00

  • Fungitoxic action of dithanes in presence of surfactant micelles.

    abstract::A rationale of arriving at the concentration of surfactant additives in the pesticidal formulations has been discovered. Fungitoxic activity of each of the two dithanes, Dithane M-45 (maneb) and Dithane Z-78 (zineb) has been estimated in the presence of various concentrations of three surfactants namely sodium lauryl ...

    journal_title:Indian journal of experimental biology

    pub_type: 杂志文章

    doi:

    authors: Gajjar L,Dubey RS,Srivastava RC

    更新日期:1996-04-01 00:00:00

  • Evaluation of topical formulations of aqueous extract of Centella asiatica on open wounds in rats.

    abstract::Formulations (ointment, cream and gel) of aqueous extract of C. asiatica, when applied topically, thrice daily for 24 days on the open wounds in rats increased cellular proliferation and collagen synthesis at the wound site, as evidenced by increase in collagen content and tensile strength. The treated wounds epitheli...

    journal_title:Indian journal of experimental biology

    pub_type: 杂志文章

    doi:

    authors: Sunilkumar,Parameshwaraiah S,Shivakumar HG

    更新日期:1998-06-01 00:00:00

  • Neuropharmacology of amide derivatives of P-GABA.

    abstract::Three lipophilic amide derivatives of phthaloyl-GABA (P-GABA), namely gamma-phthalimido N-amyl butyramide (PGA), gamma-phthalimido-N-hexylbutyramide (PGH) and gamma-phthalimido N-phenylbutyramide (PGP), were synthesized and evaluated for their hypnotic and anticonvulsant activities in mice. Both PGA and PGH showed mod...

    journal_title:Indian journal of experimental biology

    pub_type: 杂志文章

    doi:

    authors: Habibuddin M,Pal M,Pal SP

    更新日期:1992-07-01 00:00:00

  • Effect of petroleum ether extract from Hygrophila spinosa on hematological parameters and hepatorenal functions in mice.

    abstract::Multiple doses of H. spinosa were administered, ip once in a week for 4 weeks (20, 40 and 80 mg/kg body weight) and daily for one month (2, 4 and 8 mg/kg body weight). No alteration in biochemical parameters at low and moderate dose level of daily and low dose level of weekly treatment of petroleum ether extract was o...

    journal_title:Indian journal of experimental biology

    pub_type: 杂志文章

    doi:

    authors: Mazumdar UK,Gupta M,Maiti S

    更新日期:1996-12-01 00:00:00

  • Interrelationship between tumour virus receptors, A and C, coded by host cell genes in fowl.

    abstract::Bryan Standard strain of Rous Sarcoma Virus (BS-RSV) of subgroup A and pseudotype of Bryan high titre RSV(RAV-49) of subgroup C and an equal mixture of subgroup A and subgroup C virus were inoculated to 11-day old embryos of white leghorn (WL), Australorp (AL) and f1 and f2 generations of crosses between WL and AL bre...

    journal_title:Indian journal of experimental biology

    pub_type: 杂志文章

    doi:

    authors: Mehta SC,Pani PK

    更新日期:1997-01-01 00:00:00

  • Partial role of nitric oxide in infarct size limiting effect of quercetin and rutin against ischemia-reperfusion injury in normal and diabetic rats.

    abstract::Reperfusion injury is remarkable clinical issue that needs to be resolved as ischemia-reperfusion is a common phenomenon encountered in numerous clinical situations. The present communication report the involvement of nitric oxide (NO) in cardioprotection offered by flavonoids (rutin and quercetin) against myocardial ...

    journal_title:Indian journal of experimental biology

    pub_type: 杂志文章

    doi:

    authors: Challa SR,Akula A,Metla S,Gopal PN

    更新日期:2011-03-01 00:00:00

  • Role of Arogh, a polyherbal formulation to mitigate oxidative stress in experimental myocardial infarction.

    abstract::Antioxidant role of Arogh in isoproterenol induced myocardial infarction in rats has been studied. The activity of heart tissue antioxidants like glutathione, superoxide dismutase, catalase, glutathione peroxidase and glutathione-s-transferase were significantly decreased in isoproterenol administered group. The activ...

    journal_title:Indian journal of experimental biology

    pub_type: 杂志文章

    doi:

    authors: Suchalatha S,Thirugnanasambandam P,Maheswaran E,Shyamala Devi CS

    更新日期:2004-02-01 00:00:00

  • Effect of aspirin on blood-lipid interaction and lipid peroxidation phenomena in relation to partition coefficient and biological activity.

    abstract::Considering the lipophilicity of aspirin (log P = -1.15), a significant contributor to its action mechanism, interaction of the drug with the whole lipids of goat blood have been investigated using phospholipid binding and lipid peroxidation phenomena as the parameters under investigation. The lipid content change alo...

    journal_title:Indian journal of experimental biology

    pub_type: 杂志文章

    doi:

    authors: Saha A,De AU,Sengupta C

    更新日期:2000-09-01 00:00:00

  • Changes in mouse behavior induced by fetal exposure to diagnostic ultrasound.

    abstract::Pregnant Swiss albino mice were exposed to diagnostic ultrasound (3.5 MHz, 65mw, ISPTP = 1 W/cm2, ISATA = 240 W/cm2) for 10 min on day 14, 16 or 17 of gestation to assess any changes in physiological reflexes (pinna detachment, eye opening and fur development) and postnatal mortality. Changes in locomotor activity by ...

    journal_title:Indian journal of experimental biology

    pub_type: 杂志文章

    doi:

    authors: Suresh R,Devi PU,Baskar R

    更新日期:1996-09-01 00:00:00

  • Alteration in alkaline phosphatase activity of duodenal tissue following vestibulo-cerebellar modulation.

    abstract::Effect of electrolytic lesion in vestibulo-cerebellar area of male Wistar rats was investigated on duodenal alkaline phosphatase (AP) activity. Histomorphological observations of brain indicated, that extensive lesion restricted to the wide area of nodule including ventral uvula, resulted in significant fall of AP act...

    journal_title:Indian journal of experimental biology

    pub_type: 杂志文章

    doi:

    authors: Guha D,Sarkar N,Sarkar B

    更新日期:1995-10-01 00:00:00

  • Immunomodulation of macrophages by radio-detoxified lipopolysaccharide of Salmonella typhimurium.

    abstract::Lipopolysaccharide (LPS) and ratio-detoxified LPS (Rd-LPS) from Salmonella typhimurium were analysed for their ability to stimulate murine peritoneal exudate cells (PEC) and macrophages. Rd-LPS induced much more inflammatory response as compared to LPS. PEC numbers/mouse obtained were significantly higher (3-fold) in ...

    journal_title:Indian journal of experimental biology

    pub_type: 杂志文章

    doi:

    authors: Naidu MD,Chander R

    更新日期:1999-03-01 00:00:00

  • Hepato protective effect of Liv-52 against CCl4 induced lipid peroxidation in liver of rats.

    abstract::Effect of oral feeding of Liv-52, on lipid peroxidation in normal liver and damaged liver induced by CCl4 of albino rats was studied. While Liv-52 did not show any effect on normal healthy liver cells, it had a significant protective effect against damage by CCl4 as shown by significant decrease in malonaldialdehyde c...

    journal_title:Indian journal of experimental biology

    pub_type: 杂志文章

    doi:

    authors: Pandey S,Gujrati VR,Shanker K,Singh N,Dhawan KN

    更新日期:1994-09-01 00:00:00

  • Inter-conversion of free sugars and accumulation of galactomannan in response to supplied metabolic mediators during pod filling in guar.

    abstract::Detached inflorescences of guar (Cyamopsis tetragonoloba), each bearing 4 uniformly-developing pods at 42 days post anthesis (DPA), were cultured for 6 days in complete liquid medium manipulated with a fixed concentration of mannose and varying concentration of myo-inositol. Such inflorescences, but with 2 pods, were ...

    journal_title:Indian journal of experimental biology

    pub_type: 杂志文章

    doi:

    authors: Singh R,Rani E

    更新日期:2000-06-01 00:00:00

  • Inhibition of mutagenicity of food-derived heterocyclic amines by sulforaphane--a constituent of broccoli.

    abstract::Sulforaphane, a constituent of broccoli was investigated for its antimutagenic potential against different classes of cooked food mutagens (heterocyclic amines). These include imidazoazaarenes such as 2-amino-3-methylimidazo[4,5-f]quinoline (IQ), 2-amino-3,4-dimethylimidazo[4,5-f]quinoline (MeIQ), 2-amino-3,8-dimethyl...

    journal_title:Indian journal of experimental biology

    pub_type: 杂志文章

    doi:

    authors: Shishu,Kaur IP

    更新日期:2003-03-01 00:00:00

  • Laboratory evaluation of toxic baits for mosquito (Aedes aegypti) larvae.

    abstract::Toxic bait discs were prepared by incorporating the larvicide Abate (Temephos) technical, with yeast and dog biscuit (1:1), the latter forming the attractant source. These were assessed in 1, 10 and 25 litre aquaria and 100 litre drums against Aedes aegypti larvae. Floating as well as sinking bait discs were found equ...

    journal_title:Indian journal of experimental biology

    pub_type: 杂志文章

    doi:

    authors: Vartak PH,Tungikar VB,Bhonde SB,Sharma RN

    更新日期:1996-03-01 00:00:00

  • Effect of selective monoamine oxidase A and B inhibitors on footshock induced aggression in paired rats.

    abstract::Effects of a selective monoamine oxidase (MAO)--A inhibitor, clorgyline, a selective MAO-B inhibitor, deprenyl, and a non-selective MAO inhibitor, nialamide, were investigated on footshock-induced aggression (FIA) in paired rats. The doses and pretreatment times of the inhibitors used were based on an earlier reported...

    journal_title:Indian journal of experimental biology

    pub_type: 杂志文章

    doi:

    authors: Datla KP,Bhattacharya SK

    更新日期:1990-08-01 00:00:00

  • Racial divergence of a rare laboratory-evolved centromeric fission Cytorace of nasuta-albomicans complex of Drosophila.

    abstract::Fissioncytorace-1, a member of the nasuta-albomicans complex of Drosophila is an evolutionary product of centric fission, which had occurred in the chromosome X3 of Cytorace 1, a hydridization product of Drosophila nasuta nasuta male (2n=8) and Drosophila nasuta albomicans female (2n=6). Cytorace 1 (males 2n=7; female...

    journal_title:Indian journal of experimental biology

    pub_type: 杂志文章

    doi:

    authors: Bijaya T,Ramachandra NB

    更新日期:2010-05-01 00:00:00

  • Effects of drought stress on legume symbiotic nitrogen fixation: physiological mechanisms.

    abstract::Drought stress is one of the major factors affecting nitrogen fixation by legume-rhizobium symbiosis. Several mechanisms have been previously reported to be involved in the physiological response of symbiotic nitrogen fixation to drought stress, i.e. carbon shortage and nodule carbon metabolism, oxygen limitation, and...

    journal_title:Indian journal of experimental biology

    pub_type: 杂志文章,评审

    doi:

    authors: Serraj R

    更新日期:2003-10-01 00:00:00

  • Effects of calcium channel blocker, mibefradil, and potassium channel opener, pinacidil, on the contractile response of mid-pregnant goat myometrium.

    abstract::The present study was undertaken to investigate the in vitro influence of mibefradil, a calcium channel blocker, and pinacidil, a potassium channel opener, on pregnant goat myometrial spontaneous rhythmic contractility and contractions induced with the agonist, oxytocin. Longitudinal strips from the distal region of u...

    journal_title:Indian journal of experimental biology

    pub_type: 杂志文章

    doi:

    authors: Mandi G,Sarkar SN,Mishra SK,Raviprakash V

    更新日期:2005-09-01 00:00:00

  • Production of hydroquinol from p-benzoquinone using yeast.

    abstract::Reduction of p-benzoquinone to hydroquinol has been studied using Saccharomyces cerevisae and S.uvarum. Maximum conversion of p-Benzoquinone (p-BQ) to Hydroquinol (HQ) at a substrate concentration of 6%. S. cerevisae was found to be better than S. uvarum. No further conversion did take place after 60 hr. Optical innoc...

    journal_title:Indian journal of experimental biology

    pub_type: 杂志文章

    doi:

    authors: Ghosh BK

    更新日期:1995-01-01 00:00:00

  • Effect of Capparis spinosa Linn. extract on lipopolysaccharide-induced cognitive impairment in rats.

    abstract::Cognitive disorders in mankind are not uncommon. Apart from neurodegenerative diseases such as Alzheimer's (AD), various stresses also affect cognitive functions. Plants are known to be potential source of compounds that ameliorate several diseases including cognitive impairment. Here, we evaluated effect of aqueous e...

    journal_title:Indian journal of experimental biology

    pub_type: 杂志文章

    doi:

    authors: Goel A,Digvijaya,Garg A,Kumar A

    更新日期:2016-02-01 00:00:00