Abstract：
:Effects of a selective monoamine oxidase (MAO)--A inhibitor, clorgyline, a selective MAO-B inhibitor, deprenyl, and a non-selective MAO inhibitor, nialamide, were investigated on footshock-induced aggression (FIA) in paired rats. The doses and pretreatment times of the inhibitors used were based on an earlier reported in vivo dose-response and time-course study. In addition, apomorphine, a dopaminergic receptor agonist, and beta-phenylethylamine, a preferred substrate for MAO-B, were also used to garner corroborative evidence. The results of the study indicate that selective MAO-A inhibitors are likely to attenuate FIA by augmenting central serotonergic activity, while selective MAO-B inhibitors accentuate the behaviour by facilitating dopaminergic activity. A permissive role for noradrenaline could not be delineated by the available data.
journal_name
Indian J Exp Bioljournal_title
Indian journal of experimental biologyauthors
Datla KP,Bhattacharya SKsubject
Has Abstractpub_date
1990-08-01 00:00:00pages
742-5issue
8eissn
0019-5189issn
0975-1009journal_volume
28pub_type
杂志文章abstract：:Lymphatic filariasis, commonly called elephantiasis, poses a burden of estimated level of 5.09 million disability adjusted life year. Limitations of its sole drug, diethylcarbamazine (DEC) drive exploration of effective filarial target. A few plant extracts having polyphenolic ingredients and some synthetic compounds ...
journal_title：Indian journal of experimental biology
pub_type： 杂志文章
doi：
更新日期：2015-11-01 00:00:00
abstract：:Considering the lipophilicity of aspirin (log P = -1.15), a significant contributor to its action mechanism, interaction of the drug with the whole lipids of goat blood have been investigated using phospholipid binding and lipid peroxidation phenomena as the parameters under investigation. The lipid content change alo...
journal_title：Indian journal of experimental biology
pub_type： 杂志文章
doi：
更新日期：2000-09-01 00:00:00
abstract：:Significant degenerative changes were observed in the kidney tissue of untreated neonatal streptozotocin (n0STZ)-induced type-II diabetic rats. These degenerative changes were diminished in the kidney tissue of diabetic animals given glibenclamide and Aloe leaf gel and pulp extracts. Kidney lipid peroxidation levels w...
journal_title：Indian journal of experimental biology
pub_type： 杂志文章
doi：
更新日期：2004-01-01 00:00:00
abstract：:The properties of biophoton signals emitted by samples of lichen species P. tinctorum are investigated. The shape of a light induced signal is determined from 5 ms onwards using successively the bin resolution of 1, 10 and 100 ms; 1000 measurements in successive bins are made at each resolution. The measurement of the...
journal_title：Indian journal of experimental biology
pub_type： 杂志文章
doi：
更新日期：2003-05-01 00:00:00
abstract：:A bioactive compound with antibacterial activity was isolated and purified from the extract of leaves of sunflower, Helianthus annuus. The bioactive compound was characterized using 1H and 13C NMR. The compound induced auxin, gibberellins and cytokinin in Oryza sativa and Phaseolus mungo. It also showed activity again...
journal_title：Indian journal of experimental biology
pub_type： 杂志文章
doi：
更新日期：2008-12-01 00:00:00
abstract：:A gene encoding beta toxin was amplified by polymerase chain reaction from C. perfringens type C isolate and cloned in pUC 19 vector. The nucleotide sequence was identical with C. perfringens type B beta toxin gene sequence. The Southern hybridization using labelled beta toxin gene probe revealed the presence of posit...
journal_title：Indian journal of experimental biology
pub_type： 杂志文章
doi：
更新日期：2002-01-01 00:00:00
abstract：:Absence of centrilobular necrosis, cirrhosis and giant hepatic cells with a large nucleus were significant observations in the liver of CCl4 treated rats following unilateral parathyroidectomy. Increased number of mitochondria and presence of binucleated cells indicated hepatic regeneration in unilaterally parathyroid...
journal_title：Indian journal of experimental biology
pub_type： 杂志文章
doi：
更新日期：1997-05-01 00:00:00
abstract：:There was a significant increase in fucose (52%), total hexoses (16%) and hexosamine (56%) except sialic acid, which was reduced (77%) in the microvillus membrane of infants born to rat mothers made diabetic by injecting alloxan on day 3 of gestation. Expressed on the protein basis there were a significant increase in...
journal_title：Indian journal of experimental biology
pub_type： 杂志文章
doi：
更新日期：2012-01-01 00:00:00
abstract：:On the basis of inhibition analysis, tyrosine uptake in mouse mammary gland was found to be mediated by Na(+)-dependent and Na(+)-independent systems. Na(+)-dependent system was insensitive to 2-(methylamino) isobutyric acid (MeAIB), with an apparent Km of 1.67 mM and maximal velocity 74.5 nmol.g-1 cell. min-1. Compet...
journal_title：Indian journal of experimental biology
pub_type： 杂志文章
doi：
更新日期：1996-08-01 00:00:00
abstract：:Thalidomide provided significant protection against tri nitro benzene sulfonic acid induced colitis. Combination therapy also reduced colonic inflammation and all the biochemical parameters (myeloperoxidase assay, malondialdehyde assay and tumor necrosis factor-alpha, estimation) were significant as compared to contro...
journal_title：Indian journal of experimental biology
pub_type： 杂志文章
doi：
更新日期：2011-09-01 00:00:00
abstract：:Fishmeal extract bile salt lactose agar (FEBLA), a new differential medium for enteric bacteria was developed and evaluated for its ability to grow and differentiate lactose fermenters (LF) from non-lactose fermenters (NLF) in comparison with MacConkeys agar. Performance of FEBLA was at par with the latter. On FEBLA m...
journal_title：Indian journal of experimental biology
pub_type： 杂志文章
doi：
更新日期：2006-08-01 00:00:00
abstract：:The whole seed extract of S. nux vomica (in low doses) effectively neutralized Daboia russelii venom induced lethal, haemorrhage, defibrinogenating, PLA2 enzyme activity and Naja kaouthia venom induced lethal, cardiotoxic, neurotoxic, PLA2 enzyme activity. The seed extract potentiated polyvalent snake venom antiserum ...
journal_title：Indian journal of experimental biology
pub_type： 杂志文章
doi：
更新日期：2004-05-01 00:00:00
abstract：:With respect to 31 different selected test bacteria, all sensitive to benzyl penicillin (Pc), ampicillin (Ap), methicillin (Me), ceporan (Ce), cloxacillin (Cx), streptomycin (Sm), kanamycin (Km), gentamicin (Gm), chloramphenicol (Cm), tetracycline (Tc), polymyxin (Pm) as well as ambodryl [Am; an antihistamine (bromodi...
journal_title：Indian journal of experimental biology
pub_type： 杂志文章
doi：
更新日期：1990-03-01 00:00:00
abstract：:Paired samples of serum and hydrocele fluid of filarial patients associated with hydrocele were analysed for filarial antibody and antigen. Sera samples showed higher titers of filarial antibody and antigen compared to their corresponding hydrocele fluid samples. HFIgG isolated from hydrocele fluid was equally useful ...
journal_title：Indian journal of experimental biology
pub_type： 杂志文章
doi：
更新日期：1993-01-01 00:00:00
abstract：:Naturally fertilized Microhyla ornata and Xenopus laevis embryos at dorsal lip of blastopore stage were exposed to 0.3, and 0.6% sodium chloride for high salinity treatment and dilute hydrochloric acid and sodium hydroxide for treatment with low and high pH, respectively. After treatment for different durations, embry...
journal_title：Indian journal of experimental biology
pub_type： 杂志文章
doi：
更新日期：2012-08-01 00:00:00
abstract：:The neutral detergent fiber (NDF) isolated from coconut kernel was digested with cellulase and hemicellulase and the residual fiber rich in hemicellulose (without cellulose) and cellulose (with out hemicellulose) were fed to rats and compared with a fiber free group. The results indicate that hemicellulose rich fiber ...
journal_title：Indian journal of experimental biology
pub_type： 杂志文章
doi：
更新日期：1998-08-01 00:00:00
abstract：:Protective efficacy of DL-alpha lipoic acid on adriamycin induced hepatotoxicity was evaluated in rats. Adriamycin toxicity, induced by a single injection (ip; 15 mg/kg body wt), was expressed by an elevation in alanine transaminase, aspartate transaminase, bilirubin levels in serum and alkaline phosphatase, lactate d...
journal_title：Indian journal of experimental biology
pub_type： 杂志文章
doi：
更新日期：2007-12-01 00:00:00
abstract：:Octapeptide (OP)/FSH-Receptor Binding Inhibitor-8 (FRBI-8), is a synthetic peptide corresponding to N-terminal sequence of purified fraction of Follicle Stimulating Hormone Binding-Inhibitor (FSHBI), isolated earlier from human ovarian follicular-fluid. In order to avoid the repeated drug-administration, OP-loaded, po...
journal_title：Indian journal of experimental biology
pub_type： 杂志文章
doi：
更新日期：2013-12-01 00:00:00
abstract：:The present study is planned to assess the diagnostic relevance of silver stained nucleolar organizer regions (NORs) in discriminating benign from malignant lesions of the breast and to ascertain the interobserver variability in the enumeration of AgNOR counts. Forty four specimens of benign and malignant breast tissu...
journal_title：Indian journal of experimental biology
pub_type： 杂志文章
doi：
更新日期：1995-10-01 00:00:00
abstract：:The frequency and types of acrocentric chromosome association were quantitatively analysed in a Down syndrome child with unusual karyotype, 46, XX, -14, -22, t dic (14p;22p), +21, 21S+. Father and 4 sibs were heterozygous carriers for t dic (14p;22p). The variant 21S+ was inherited from the mother. The occurrence of t...
journal_title：Indian journal of experimental biology
pub_type： 杂志文章
doi：
更新日期：1990-06-01 00:00:00
abstract：:To evaluate the cardioprotective potential of Inula racemosa in myocardial ischemic-reperfusion injury, Wistar male albino rats were randomly divided into four groups. The group I and II animals were administered saline orally {(sham, ischemia- reperfusion (I-R) control group)} and animals of group III and group IV re...
journal_title：Indian journal of experimental biology
pub_type： 杂志文章
doi：
更新日期：2010-09-01 00:00:00
abstract：:Leaf explants collected from flowering plants of Vanda spathulata were cultured in Mitra medium with combinations of 6-benzyladenine (BA; 13.2-88.8 microM) and indole-3-acetic acid (IAA; 0.0 -85.6 microM). Combination of BA (66.6 microM) and IAA (28.5 microM) induced maximum shoots (17.33) from foliar meristems (leaf ...
journal_title：Indian journal of experimental biology
pub_type： 杂志文章
doi：
更新日期：2003-08-01 00:00:00
abstract：:"Triphala", the Ayurvedic wonder is used traditionally for the treatment of different types of diseases since antiquity. The hydroalcoholic extracts of the three components of Triphala powder demonstrated varying degrees of strain specific antibacterial activity against multidrug-resistant uropathogenic bacteria. Term...
journal_title：Indian journal of experimental biology
pub_type： 杂志文章
doi：
更新日期：2013-09-01 00:00:00
abstract：:While there is an emphasis on the early glycemic control for its long-term benefits in preventing microvascular complications of diabetes, the biochemical mechanisms responsible for the long-lasting effects are not clearly understood. Therefore the impact of early insulin (EI) versus late insulin (LI) treatment on dia...
journal_title：Indian journal of experimental biology
pub_type： 杂志文章
doi：
更新日期：2013-01-01 00:00:00
abstract：:Thirteen strains of M. bovoculi, 6 from frozen bull-semen (3.5% of 168), 3 from neat bull-semen (3.0% of 100), one each from heart blood and stomach contents of aborted foetus of 85 (1.18%) bovine-abortions, one each from stomach contents and pooled internal organs of 9 (11.1%) stillborn calves, were isolated. All the...
journal_title：Indian journal of experimental biology
pub_type： 杂志文章
doi：
更新日期：2004-09-01 00:00:00
abstract：:Ganoderma lucidum, a white rot fungus, was exploited for its potentials to produce xylanase employing shake and solid-state culture conditions. Different culture conditions such as pH, temperature, carbon and nitrogen requirements for its growth and production of xylanase were optimized. The culture media pH 6.0-7.0 a...
journal_title：Indian journal of experimental biology
pub_type： 杂志文章
doi：
更新日期：2003-06-01 00:00:00
abstract：:Goat epididymal and ejaculated spermatozoa were incubated in Krebs-Ringer bicarbonate buffer containing pyruvate and lactate as energy source. A 3 hr incubation for epididymal and 4 hr for ejaculated spermatozoa was required for the capacitation and acrosome reaction to take place. Calcium is an essential requirement ...
journal_title：Indian journal of experimental biology
pub_type： 杂志文章
doi：
更新日期：1989-11-01 00:00:00
abstract：:Effects of Indian red scorpion (M. tamulus concanesis; MBT) venom on the compound action potential (CAP) of sciatic nerve in vitro were examined. MBT venom (0.1-6.0 micrograms/ml) prolonged the repolarization time and refractory period of the CAP in a concentration-dependent manner with maximal potentiation occurring ...
journal_title：Indian journal of experimental biology
pub_type： 杂志文章
doi：
更新日期：1998-11-01 00:00:00
abstract：:Fluorescent pseudomonads were isolated from the rhizosphere of rice and sugarcane and examined for their biodiversity. All fifty strains of the fluorescent pseudomonads produced indole acetic acid. Among these pseudomonads, halves of sugarcane rhizosphere isolates and one isolate from the rice rhizosphere exhibited ph...
journal_title：Indian journal of experimental biology
pub_type： 杂志文章
doi：
更新日期：2005-01-01 00:00:00
abstract：:Reduction of p-benzoquinone to hydroquinol has been studied using Saccharomyces cerevisae and S.uvarum. Maximum conversion of p-Benzoquinone (p-BQ) to Hydroquinol (HQ) at a substrate concentration of 6%. S. cerevisae was found to be better than S. uvarum. No further conversion did take place after 60 hr. Optical innoc...
journal_title：Indian journal of experimental biology
pub_type： 杂志文章
doi：
更新日期：1995-01-01 00:00:00
