Role of Arogh, a polyherbal formulation to mitigate oxidative stress in experimental myocardial infarction.

Abstract:

:Antioxidant role of Arogh in isoproterenol induced myocardial infarction in rats has been studied. The activity of heart tissue antioxidants like glutathione, superoxide dismutase, catalase, glutathione peroxidase and glutathione-s-transferase were significantly decreased in isoproterenol administered group. The activity of ceruloplasmin and levels of glutathione, vitamins E and C were also found to be substantially decreased in serum with a concomitant rise in lipid peroxide levels after isoproterenol exposure to rats. The synergistic effect of Arogh pretreatment, significantly suppressed the alterations induced by isoproterenol alone in rats.

journal_name

Indian J Exp Biol

authors

Suchalatha S,Thirugnanasambandam P,Maheswaran E,Shyamala Devi CS

keywords:

subject

Has Abstract

pub_date

2004-02-01 00:00:00

pages

224-6

issue

2

eissn

0019-5189

issn

0975-1009

journal_volume

42

pub_type

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