Abstract:
:Cardioprotective effect of ethanolic extract of Terminalia chebula fruits (500 mg/kg body wt) was examined in isoproterenol (200 mg/kg body wt) induced myocardial damage in rats. In isoproterenol administered rats, the level of lipid peroxides increased significantly in the serum and heart. A significant decrease was observed in the activity of the myocardial marker enzymes with a concomitant increase in their activity in serum. Histopathological examination was carried out to confirm the myocardial necrosis. T. chebula extract pretreatment was found to ameliorate the effect of isoproterenol on lipid peroxide formation and retained the activities of the diagnostic marker enzymes.
journal_name
Indian J Exp Bioljournal_title
Indian journal of experimental biologyauthors
Suchalatha S,Shyamala Devi CSkeywords:
subject
Has Abstractpub_date
2004-02-01 00:00:00pages
174-8issue
2eissn
0019-5189issn
0975-1009journal_volume
42pub_type
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