Abstract:
:Lactobacillus acidophilus strains tested showed inhibitory activity towards Salmonella typhi, Staphylococcus aureus, Escherichia coli, Proteus vulgaris and Yersinia enterocolitica. However, wide variations in the activity of the strains were observed. Antagonistic activity of the strains exhibited high heat stability (120 min at 92 degrees C, 15 min at 121 degrees C) but it was markedly influenced by changes in pH. Effect of kind of milk on antagonistic activity was variable, whereas skimming had no significant effect.
journal_name
Indian J Exp Bioljournal_title
Indian journal of experimental biologyauthors
Gupta PK,Mital BK,Garg SKsubject
Has Abstractpub_date
1996-12-01 00:00:00pages
1245-7issue
12eissn
0019-5189issn
0975-1009journal_volume
34pub_type
杂志文章abstract::The in vitro percutaneous absorption of verapamil hydrochloride (VHCl) was investigated in order to assess its feasibility for transdermal development. The experiments were carried across mice and guinea pig skins using Keshary-Chien diffusion cell. The values of diffusion rate (J) and permeability coefficient (Kp) ac...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:1996-05-01 00:00:00
abstract::Bipolar concentric electrodes were implanted in extreme lateral regions of hypothalamus having coordinates (A12.5 mm, L 3.5-3.7 mm, V 3.0-3.7 mm). These sites were electrically stimulated using biphasic square wave pulses (1 ms, 60 Hz) at a current strength ranging from 300-800 microA to evoke predatory attack on an a...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:1997-04-01 00:00:00
abstract::Intramuscular injection of 3-[p-(N-2-pyrimidylsulfamoyl)phenylhydrazono]pentane-2,4-dio ne (compound I) resulted in decrease in haemoglobin and alanine transaminase (ALT) and increase in aspartate transaminase (AST) values in albino rats. The serum glucose was found to decrease and after administration of 14 doses of ...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:1996-10-01 00:00:00
abstract::Dicarboxylic acids and a few amino acids were found to support mitochondrial phosphorylation in A. ceylanicum. Anaerobiasis markedly reduced this activity. Maximum effect was observed on succinate supported phosphorylation which in anaerobic atmosphere yielded only 2% ATP compared to that in the presence of air. Known...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:1990-06-01 00:00:00
abstract::A protocol has been devised for enhanced in vitro regeneration of critically endangered Mantisia spathulata Schult. and Mantisia wengeri Fischer. Highest Bud Forming Capacity (BFC) of 6.10 +/- 0.55 with an average of 19.93 +/- 3.19 roots was obtained for M. spathulata within 5-6 weeks in Murashige and Skoogs (MS) medi...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:2009-02-01 00:00:00
abstract::Considering the lipophilicity of aspirin (log P = -1.15), a significant contributor to its action mechanism, interaction of the drug with the whole lipids of goat blood have been investigated using phospholipid binding and lipid peroxidation phenomena as the parameters under investigation. The lipid content change alo...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:2000-09-01 00:00:00
abstract::Hydantoin derivatives, including phenytoin (5,5-diphenylhydantoin), have recently gained attention as they possess a variety of important biochemical and pharmacological properties. Nevertheless, available information on anticancer activity of hydantoin derivatives is still scarce. Here, we evaluated possible antileuk...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:2016-09-01 00:00:00
abstract::Saponins, isolated from M. butyracea, were assessed for their acute and subacute oral toxicity in albino rats. Acute doses of saponins caused mortalities and LD50 and LD90 values were 330 and 430 mg/kg body wt respectively. Severe diarrhoea, restlessness and histopathological changes were observed in liver and kidney....
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:1990-07-01 00:00:00
abstract::The effect of the administration of three different concentrations (2.25, 1.13 and 0.56 mg/100 g body weight) of dimethoate on the urinary excretion of total, non dialysable and free hydroxyproline were studied in female albino rats. Compared to controls, the urine contents were significantly lower in higher concentra...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:1992-06-01 00:00:00
abstract::Antinociceptive activity of methanolic extract of leaves of A. aspera was studied by peripheral/non-narcotic model of nociception like acetic acid induced writhing syndrome test and central/narcotic models like hot plate and tail flick tests. The methanolic extract of the plant, administered orally (@ 300, 600 and 900...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:2010-08-01 00:00:00
abstract::Pseudomonas aeruginosa is one of the commonest pathogens among the pseudomonads. This organism can grow in minimal nutritional requirements. Because of the ability of pseudomonads to grow on paraffin is not commonly found among other human pathogens and the primary human pathogen being P. aeruginosa, we studied the ad...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:2007-03-01 00:00:00
abstract::Ruminal fungal isolates (Orpinomyces sp.; C-14, Piromyces sp.; C-15, Orpinomyces sp.; B-13 and Anaeromyces sp.; B-6), were evaluated under anoxic conditions for their effect on in vitro dry matter digestibility, neutral detergent fibre, acid detergent fibre and acid detergent lignin using rice and wheat straw as subst...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:2004-06-01 00:00:00
abstract::Dementia is one of the age related mental problems and a characteristic symptom of various neurodegenerative disorders including Alzheimer's disease. Certain drugs like diazepam, barbiturates and alcohol disrupt learning and memory in animals and man. However, a new class of drugs known as nootropic agents is now used...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:2006-02-01 00:00:00
abstract::Role of fatty acid binding proteins (FABPs) in modulating inhibition of human placental malate dehydrogenase by palmitoyl-CoA and oleate has been studied. Activity of human placental cytosolic malate dehydrogenase is detected throughout the gestation, showing a peak at midgestation (20-25 weeks). Inhibition (50%) of t...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:1994-11-01 00:00:00
abstract::The present investigation is aimed to justify the validity of traditional practice of using the frog skin in wound healing. Studies were carried out on skin wounds from female albino rats of Wistar strain weighing 100-120 g. The wounds of standard size (5 cm2) were created in the experimental and control groups. The e...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:1995-09-01 00:00:00
abstract::Aeromonas sp. from Lamellidens marginalis produced L-asparaginase when grown at 37 degrees C. The optimum enzyme activity was at pH 9 when temperature was 45 degrees C. Half-life of partially purified enzyme at 50 degrees C and 55 degrees C was 35 and 20 min, respectively. Activation and deactivation energies of parti...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:2000-11-01 00:00:00
abstract::Induction of differentially stained sister chromatids at G2/M and determination of baseline sister chromatid exchanges (SCEs) in ascites form of mouse sarcoma 180 cell line have been done by in vivo incorporation of 5-bromodeoxyuridine (BrdU) for two consecutive DNA replication cycles. The baseline SCE frequency is 6....
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:1992-01-01 00:00:00
abstract::Erythrocyte structure was studied in rat after uranyl nitrate (UN:5 mg/kg) intoxication. The study of pathogenic progression of UN induced renal failure (ARF) was confined to the early initiation phase (2 hr), late initiation phase (8 hr) and the maintenance phase (24 hr). Erythrocyte structure has been found to be gr...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:1992-02-01 00:00:00
abstract::The aim of the present study was to investigate the role of phosphodiesterase (PDE) enzyme inhibitors namely rolipram and theophylline in pain and inflammation in experimental animals. Rolipram, a selective PDE IV inhibitor and theophylline a nonspecific PDE inhibitor exerted dose dependent analgesic and anti-inflamma...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:2000-01-01 00:00:00
abstract::Rest-activity rhythm and quality of life (QoL) in three cohorts, namely (1) cancer in-patients, (2) out-patients, and (3) control subjects were studied. The patients of the former two groups were chosen randomly from the Regional Cancer Center, Raipur, India. All patients received chemotherapy for 3-4 consecutive days...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:2014-05-01 00:00:00
abstract::Head and neck squamous cell carcinoma (HNSCC), a common malignancy that possibly involves a combination of exposure to the carcinogens and inherited genetic differences in the enzymes catalyzing their metabolism. Alcohol and tobacco consumption are the primary environmental risk factors, while polymorphism in various ...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章,评审
doi:
更新日期:2010-07-01 00:00:00
abstract::The 50% ethanolic extract of the root bark of C. odorata administered orally at the dose of 1g/kg body weight/day for 60 days resulted in decreased epididymal sperm motility and sperm count in male albino rats. Morphological abnormalities were also observed in the sperms. The testicular glycogen, the activities of 3be...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:2006-12-01 00:00:00
abstract::A bench-scale biotrickling filter was operated in the laboratory for the treatment of dimethyl sulphide (DMS). The biotrickling filter was packed with pre-sterilized polyurethane foam and seeded with biomass developed from garden soil enriched with DMS. The biotrickling filter was operated for the generation of proces...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:2013-11-01 00:00:00
abstract::Feeding calculi producing diet (CPD) to rats for 4 weeks produced calcium oxaltate stones. Supplementation of sodium citrate to CPD (c-CPD) prevented stone formation. Except oxalate, the excretion of calcium, phosphorus and magnesium was restored to normal in c-CPD fed rats. The CPD fed rats exhibited increase in glyc...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:1992-08-01 00:00:00
abstract::Cigarette smoking has been established as a major risk factor for atherosclerosis and also for lung cancer. Nicotine is one of the major components of cigarette smoke which is believed to be partly responsible for the deleterious effect of cigarette smoke. There was significant alteration in the concentration of glyco...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:1992-03-01 00:00:00
abstract::Infectious pancreatic necrosis virus (IPNV) from lake trout of Cornwall lake (LT-IPNV), from trout of Jasper (Ja-IPNV) and Arctic char of Northwest Territories (AC-IPNV) are the three isolates recorded from western Canada. Two segments (nt 453-674 and nt 1197-1503) from VP2 coding region of RNA of the isolates were am...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:1994-08-01 00:00:00
abstract::Protective effect of sex steroid hormones on aflatoxin-induced cytotoxicity on RBC (hemolysis) was examined in vitro. Addition of aflatoxin (2 micrograms/ml) in RBC suspension caused significant increase in hemolysis. Concurrent addition of aflatoxin (2 micrograms/ml) and estradiolbenzoate (100-1200 pg/ml) in RBC susp...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:1993-09-01 00:00:00
abstract::Presence of angiotensin converting enzyme (ACE, EC 3.4.15.1) in female reproductive tract and its interaction with semen has been investigated in domestic fowl. Higher activity of ACE was detected in homogenates of infundibulum region followed by magnum and relatively low level was noticed in rest of the parts of the ...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:1993-07-01 00:00:00
abstract::Leukotrienes play a part in inflammatory response. The unique role of the enzyme 5-lipoxygenase (5-LOX) in the production of leukotrienes makes it a likely therapeutic target for inflammatory conditions like asthma, rheumatoid arthritis, psoriasis, and inflammatory bowel disease (IBD). The aim of the present study was...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:2004-07-01 00:00:00
abstract::Seeds of Ocimum sanctum L. (Labiatae; popularly known as 'Tulsi' in Hindi and 'Holy Basil' in English) contain a pale yellow colored fixed oil. The oil possesses antiinflammatory activity due to dual inhibition of arachidonate metabolism supplemented by antihistaminic activity. The antiinflammatory activity is not dep...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章,评审
doi:
更新日期:2007-05-01 00:00:00