Abstract:
:Protective effect of sex steroid hormones on aflatoxin-induced cytotoxicity on RBC (hemolysis) was examined in vitro. Addition of aflatoxin (2 micrograms/ml) in RBC suspension caused significant increase in hemolysis. Concurrent addition of aflatoxin (2 micrograms/ml) and estradiolbenzoate (100-1200 pg/ml) in RBC suspension significantly retarded aflatoxin-induced hemolysis. Similarly, addition of aflatoxin (2 micrograms/ml) along with testosterone propionate (5-60 ng/ml) in RBC suspension retarded aflatoxin-induced hemolysis. Among the two synthetic hormones studied estradiolbenzoate was more potent than testosterone propionate.
journal_name
Indian J Exp Bioljournal_title
Indian journal of experimental biologyauthors
Raval PJ,Verma RJsubject
Has Abstractpub_date
1993-09-01 00:00:00pages
780-1issue
9eissn
0019-5189issn
0975-1009journal_volume
31pub_type
杂志文章abstract::The present study deals with the effect of butylated hydroxy anisole, propyl gallate and alpha-tocopherol on ATPase activity of brain and heart in ageing male mice. The activity of both the tissues significantly increased during pre-reproductive and reproductive phases. However, during the post-reproductive phase, ATP...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:1992-04-01 00:00:00
abstract::In order to find out the effect of chronic ethanol administration on testicular antioxidant system and steroidogenic enzyme activity, male rats fed with ethanol 1.6g/kg body weight per day for four weeks were studied. Besides a drastic reduction in body and testis weight, there was decrease in ascorbic acid, reduced g...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:2005-05-01 00:00:00
abstract::Administration of ethanol extract of stem bark from Z. rhoifolium (EEtOH-ZR) induced hypotension associated with a dual effect in heart rate in normotensive rats. This response was highlighted in spontaneously hypertensive rats (SHR). In rat superior mesenteric artery rings, the cumulative addition of EEtOH-ZR (0.1-75...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:2013-08-01 00:00:00
abstract::The toxic effect of dried berries powder of P. cubeba, dried fruit powder of P. longum and T. terrestris singly as well as in combination [binary (1:1) and tertiary (1:1:1)] were studied against snail L. exustus. Toxicity of these plant products were time and concentration dependent. Ethanol extracts of these plants w...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:2009-08-01 00:00:00
abstract::A study to monitor marine pollution with reference to trace elements (Fe, Zn, Mn and Cu) on T. attenuata, commonly called as screw shell over a period of one year on the whole body and various organs, viz. digestive diverticula, foot, mantle and ovary was conducted from the sandy beach of Porto Novo Coast (Lat 11 degr...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:1999-11-01 00:00:00
abstract::In the present study HD-03, a herbal formulation was investigated for its anti-cholestatic activity in TAA-induced cholestasis in anaesthetized guinea pigs. Administration of TAA at a dose of 100 mg/kg body wt significantly reduced the bile flow, bile acid and bile salt excretion. Pretreatment with HD-03 at a dose of ...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:1999-04-01 00:00:00
abstract::Two wheat varieties, T. durum (HD 4502) and T. aestivum (Kalyansona) were examined for photosynthesis rate and contents of sugars and rubisco protein in the flag leaf, at forenoon and afternoon at anthesis stage. A decrease in photosynthesis rate was observed in the afternoon compared to forenoon in both the varieties...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:2001-11-01 00:00:00
abstract::Significant reduction (68.38%) in sheath blight disease of rice was noticed when foliar spray of a systemic fungicide, kitazin (480 micrograms mg-1), was applied twice at an interval of 2 days before inoculation. SDS-PAGE analysis of proteins of Rhizoctonia-infected rice leaf sheaths revealed the presence of 16 protei...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:1997-06-01 00:00:00
abstract::In vitro treatment of erythrocytes of normal and hypercholesterolemic rats with N-nitrosodiethylamine (NDEA), an important carcinogen frequently present in human environment and food chain resulted in a marginal increase in osmotic fragility of erythrocytes without affecting their antioxygenic potential as evidenced b...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:2002-09-01 00:00:00
abstract::In an attempt to evaluate the effect and interaction of ethanol on endosulfan-induced hepatotoxicity in vivo to adult male rats, both, endosulfan (7.5 mg/kg body wt) and ethanol (1.5 g/kg body wt) were studied separately as well as in combination after a chronic oral exposure of 30 days. When fed separately, both the ...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:1991-11-01 00:00:00
abstract::An unusual nucleolar organizer region (double NOR) on chromosome 13 was observed in a Down syndrome child [47, XY, +21, dNOR(13)]. The variant chromosome was inherited from the mother [46, XX, dNOR(13)]. The extra chromosome 21 in the proband was maternal origin. The frequency of NOR chromosome association showed rela...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:1989-10-01 00:00:00
abstract::Influence of piroxicam (PX) on glibenclamide (GL) induced hypoglycemia has been studied in rats, healthy human volunteers and diabetics. GL per se has significantly reduced blood sugar levels in rats and in humans. PX per se has significantly reduced BSLs, in diabetics, while having no significant influence on blood s...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:1992-04-01 00:00:00
abstract::An efficient method has been developed for large-scale multiplication of Curculigo orchioides (Hypoxidaceae), an endangered medicinal plant, through direct bulbil formation from leaf explants in shake flask cultures. Leaf-segments (7 x 10 mm) were cultured in B5 liquid medium containing KNO3 (200 mgNL-1), (NH4)2SO4 (5...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:2000-02-01 00:00:00
abstract::Limb remote ischemic postconditioning (LRIP) can reduce ischemia-reperfusion injury (IRI), but its mechanisms are still unclear. We hypothesize that LRIP reduces IRI by reversing eNOS uncoupling. Focal ischemia was induced in Sprague-Dawley rats by middle cerebral artery occlusion for 2 h followed by a 24 h reperfusio...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:2014-06-01 00:00:00
abstract::Nine halophilic archaea viz., Halobacterium salinarum, Halobacterium sp.1, Halobacterium sp.2, Halobaculum sp., Halococcus saccharolyticus, Halorubrum saccharovorum, Haloterrigena turkmenica, Halogeometricum sp. and Natrialba sp. isolated from marine salterns around Bhavnagar coast were screened for siderophore produc...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:2006-04-01 00:00:00
abstract::Radiosensitizing effects of combination of a minor groove DNA ligand, Hoechst-33342, with the glucose analogue and inhibitor of glycolysis, 2-deoxy-D-glucose (2-DG) have been investigated in Ehrlich ascites tumour (EAT) bearing mice following focal irradiation of the tumour with 60Co gamma-rays. Treatment-induced tumo...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:1999-09-01 00:00:00
abstract::Effect of a triterpene isolated from the acetone soluble part of petroleum ether extract of R. cordifolia was studied on convulsions induced by maximum electro shock (MES), electrical kindling and various chemoconvulsants in rats and mice. The effect of triterpene was also investigated on behavior and gamma-aminobutyr...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:2000-07-01 00:00:00
abstract::Effect of Swerchirin (1:8 dihydroxy 3:5 dimethoxy xanthone) isolated from hexane fraction of Swertia chirayita on the blood sugar level of healthy and streptozotocin treated rats was studied. Streptozotocin was administered in citrate buffer (pH-4.5) intravenously / 35 and 65 mg/kg body wt to Charles Foster strain alb...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:1991-07-01 00:00:00
abstract::Cysticercus fasciolaris, the larval form of Taenia taeniaformis is commonly encountered in rodents most often in mice and rats through contaminated feed and bedding materials. The infection is asymptomatic and is considered harmless, but its presence in the laboratory mice/rats could lead to misinterpretation of resul...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:1998-05-01 00:00:00
abstract::A highly stable lipase from Pseudomonas aeruginosa KKA-5 was produced by batch cultivation technique employing shake flask and 5 L-bioreactor. The bioreactor was run at different airflow rates. Low airflow rates (1 and 3 L/min), did not lead to effective growth and lipase production. Growth increased by about one orde...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:1999-05-01 00:00:00
abstract::Maize (Zea mays L. cv kanaujia) plants grown with Zn [10 (control), 0.1 (low) and 20 microM (high)], were investigated for concentration of antioxidants and activities of antioxidative enzymes in leaves. Young leaves of low Zn plants developed whitish-necrotic spots. Leaves of both low and high Zn plants showed decrea...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:2002-08-01 00:00:00
abstract::There exists a possibility of interactions of histaminergic system with other neurotransmitters and their receptors in the central nervous system. Experimental evidences suggest a possible inhibitory influence of histaminergic system on the dopaminergic system. To elucidate the possible interaction between the histami...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:2000-10-01 00:00:00
abstract::Dual role of TGF-beta signaling in breast tumorigenesis as an inhibitor in early stages and promoter in advanced stages has been well established and known as TGF-beta switch. However, the biological mechanisms needs to be explored. Aim of the present study was to look for the usefulness of TGF-beta as a predictive ma...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:2011-11-01 00:00:00
abstract::The present study was designed to investigate the putative antidepressant and anxiolytic-like effects of N-n-Butylquinoxalin-2-carboxamide (4n), a novel 5-HT3 receptor antagonist, with an optimal log P (2.01) and pA2 value (7.3) greater than ondansetron (6.9) using rodent behavioural models of depression and anxiety. ...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:2012-09-01 00:00:00
abstract::Ascaridia galli, the common intestinal nematode, remains a major cause of economic loss in the poultry industry in developing countries. Treatments using chemicals are not only expensive but also affect host health. Plant extracts as better alternative is gaining significance. Here, we have studied the effects of alco...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:2015-07-01 00:00:00
abstract::Head and neck squamous cell carcinoma (HNSCC), a common malignancy that possibly involves a combination of exposure to the carcinogens and inherited genetic differences in the enzymes catalyzing their metabolism. Alcohol and tobacco consumption are the primary environmental risk factors, while polymorphism in various ...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章,评审
doi:
更新日期:2010-07-01 00:00:00
abstract::Stocks of three Indian Chandipura virus (CHPV) isolates; one isolate from an adult febrile case in 1965 from Chandipura town, Maharashtra, and two isolates from two pediatric encephalitis cases from Andhra Pradesh, 2003 were inoculated in 10-day-old chick embryos by allantoic route. All three virus isolates replicated...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:2005-10-01 00:00:00
abstract::A strain of T. chilonis, an egg parasitoid of lepidopteran pests tolerant to the most commonly used cyclodiene insecticide--endosulfan was developed in the laboratory. Tolerance to endosulfan was induced by exposing adult parasitoids sequentially from a sub-lethal concentration (0.004%) to the field recommended concen...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:2006-07-01 00:00:00
abstract::Fine structural variations in two different types of muscles of frog (Rana cyanophlictis) subjected to sciatectomy were studied electronmicroscopically. Gastrocnemius muscle showed marked myofibrillar disarray and degeneration due to sciatectomy, while sartorius muscle was relatively less affected. The extent of sciat...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:1989-10-01 00:00:00
abstract::Juvenoids, applied topically on larvae of Corcyra cephalonica harbouring the larvae of the parasitoid, produce various types of developmental derangements in parasitoid C. blackburni. The deformed morphs, e.g., apparently normal adults, adultoids and prolonged larvae were developed at different rates by different dose...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:2001-02-01 00:00:00