Abstract：
:Feeding calculi producing diet (CPD) to rats for 4 weeks produced calcium oxaltate stones. Supplementation of sodium citrate to CPD (c-CPD) prevented stone formation. Except oxalate, the excretion of calcium, phosphorus and magnesium was restored to normal in c-CPD fed rats. The CPD fed rats exhibited increase in glycolic acid oxidase (GAO) and lactate dehydrogenase (LDH) activities and only GAO activity was partially restored in c-CPD fed rats. Kidney sub-cellular fractions of calculi producing diet (CPD) fed rats showed increased susceptibility for lipid peroxidation in presence of promotors. Antioxidant enzyme activities of superoxide dismutase (SOD), catalase and glutathione peroxidase and antioxidant concentrations of reduced glutathione, total thiols, ascorbic acid and vitamin E were significantly decreased while the xanthine oxidase activity, and concentrations of hydroxyl radical, diene conjugates and hydroperoxides were significantly increased in CPD fed rats. The susceptibility to lipid peroxidation, activities of antioxidant enzymes, and the concentration of antioxidants were not normalized by feeding citrate.
journal_name
Indian J Exp Bioljournal_title
Indian journal of experimental biologyauthors
Selvam R,Bijikurien Tkeywords:
subject
Has Abstractpub_date
1992-08-01 00:00:00pages
705-10issue
8eissn
0019-5189issn
0975-1009journal_volume
30pub_type
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journal_title：Indian journal of experimental biology
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更新日期：1992-11-01 00:00:00
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journal_title：Indian journal of experimental biology
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journal_title：Indian journal of experimental biology
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journal_title：Indian journal of experimental biology
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journal_title：Indian journal of experimental biology
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更新日期：2005-11-01 00:00:00
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journal_title：Indian journal of experimental biology
pub_type： 杂志文章,评审
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更新日期：2006-07-01 00:00:00
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journal_title：Indian journal of experimental biology
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更新日期：1997-06-01 00:00:00
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更新日期：2000-10-01 00:00:00
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journal_title：Indian journal of experimental biology
pub_type： 杂志文章
doi：
更新日期：1995-07-01 00:00:00
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journal_title：Indian journal of experimental biology
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更新日期：2005-01-01 00:00:00
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journal_title：Indian journal of experimental biology
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更新日期：2001-12-01 00:00:00
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journal_title：Indian journal of experimental biology
pub_type： 杂志文章
doi：
更新日期：1995-01-01 00:00:00
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doi：
更新日期：2001-11-01 00:00:00
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journal_title：Indian journal of experimental biology
pub_type： 杂志文章
doi：
更新日期：1996-03-01 00:00:00
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journal_title：Indian journal of experimental biology
pub_type： 杂志文章
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更新日期：1977-10-01 00:00:00
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journal_title：Indian journal of experimental biology
pub_type： 杂志文章
doi：
更新日期：2013-11-01 00:00:00
