Abstract：
:Intestinal epithelium secretes novel unilamellar membranes having characteristics similar to lung surfactants and thus has been named Surfactant-like particles (SLP). The chemical analysis of the membranes revealed cholesterol/phospholipid molar ratio of 0.68-0.78, which is much distinct from that of the underlying microvillus membranes (1.34-1.49). The membrane contains 4-6 proteins with a molar weight of 30-120 kDa and is enriched with alkaline phosphatase, contains low amounts of disaccharidases but no Na+, K(+)-ATPase activity. The secretion of SLP is stimulated by fat feeding. Chronic ethanol ingestion also induces the formation of SLP in rat intestine. A number of physiological functions have been attributed to SLP, which include: (i) as a protective lubricant in intestinal lumen, (ii) a role in triacylglycerol transport, (iii) as a vehicle for the transport of luminal proteins into blood, (iv) as a stratum for the adhesion of microorganisms in intestinal lumen, and (v) a role in trans-signalling mechanism across the basolateral surface of enterocytes.
journal_name
Indian J Exp Bioljournal_title
Indian journal of experimental biologyauthors
Turan A,Gupta S,Mahmood Asubject
Has Abstractpub_date
2006-07-01 00:00:00pages
519-25issue
7eissn
0019-5189issn
0975-1009journal_volume
44pub_type
杂志文章,评审abstract：:Melanoma antigen-encoding gene 3 (MAGE-3) is an ideal candidate for a tumor vaccine although its potency need to be increased. Heat shock proteins (HSPs) represents a potential approach for increasing the potency of DNA vaccines. In the present study, a fusion DNA vaccine composed of Mycobacterium tuberculosis HSP70 a...
journal_title：Indian journal of experimental biology
pub_type： 杂志文章
doi：
更新日期：2010-05-01 00:00:00
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journal_title：Indian journal of experimental biology
pub_type： 杂志文章,随机对照试验
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journal_title：Indian journal of experimental biology
pub_type： 杂志文章
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更新日期：1994-09-01 00:00:00
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journal_title：Indian journal of experimental biology
pub_type： 杂志文章
doi：
更新日期：1996-10-01 00:00:00
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journal_title：Indian journal of experimental biology
pub_type： 杂志文章
doi：
更新日期：2004-05-01 00:00:00
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journal_title：Indian journal of experimental biology
pub_type： 杂志文章
doi：
更新日期：1993-01-01 00:00:00
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journal_title：Indian journal of experimental biology
pub_type： 杂志文章
doi：
更新日期：1999-11-01 00:00:00
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journal_title：Indian journal of experimental biology
pub_type： 杂志文章
doi：
更新日期：2001-03-01 00:00:00
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journal_title：Indian journal of experimental biology
pub_type： 杂志文章
doi：
更新日期：2002-09-01 00:00:00
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journal_title：Indian journal of experimental biology
pub_type： 杂志文章,评审
doi：
更新日期：2004-11-01 00:00:00
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journal_title：Indian journal of experimental biology
pub_type： 杂志文章
doi：
更新日期：2005-09-01 00:00:00
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journal_title：Indian journal of experimental biology
pub_type： 杂志文章
doi：
更新日期：1996-12-01 00:00:00
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journal_title：Indian journal of experimental biology
pub_type： 杂志文章
doi：
更新日期：1994-02-01 00:00:00
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journal_title：Indian journal of experimental biology
pub_type： 杂志文章,评审
doi：
更新日期：2003-02-01 00:00:00
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journal_title：Indian journal of experimental biology
pub_type： 杂志文章
doi：
更新日期：2001-09-01 00:00:00
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journal_title：Indian journal of experimental biology
pub_type： 杂志文章
doi：
更新日期：1990-11-01 00:00:00
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journal_title：Indian journal of experimental biology
pub_type： 杂志文章
doi：
更新日期：2015-07-01 00:00:00
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journal_title：Indian journal of experimental biology
pub_type： 杂志文章
doi：
更新日期：1990-04-01 00:00:00
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journal_title：Indian journal of experimental biology
pub_type： 杂志文章
doi：
更新日期：2000-06-01 00:00:00
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journal_title：Indian journal of experimental biology
pub_type： 杂志文章
doi：
更新日期：1992-01-01 00:00:00
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journal_title：Indian journal of experimental biology
pub_type： 杂志文章
doi：
更新日期：2003-05-01 00:00:00
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journal_title：Indian journal of experimental biology
pub_type： 杂志文章
doi：
更新日期：1990-08-01 00:00:00
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journal_title：Indian journal of experimental biology
pub_type： 杂志文章
doi：
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journal_title：Indian journal of experimental biology
pub_type： 杂志文章
doi：
更新日期：1990-01-01 00:00:00
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journal_title：Indian journal of experimental biology
pub_type： 杂志文章
doi：
更新日期：1994-03-01 00:00:00
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journal_title：Indian journal of experimental biology
pub_type： 杂志文章
doi：
更新日期：2004-09-01 00:00:00
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journal_title：Indian journal of experimental biology
pub_type： 杂志文章
doi：
更新日期：2004-04-01 00:00:00
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journal_title：Indian journal of experimental biology
pub_type： 杂志文章
doi：
更新日期：1993-12-01 00:00:00
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journal_title：Indian journal of experimental biology
pub_type： 杂志文章
doi：
更新日期：2000-09-01 00:00:00
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journal_title：Indian journal of experimental biology
pub_type： 杂志文章
doi：
更新日期：2012-11-01 00:00:00
