Response of liver antioxidant system to taurine in rats fed high fructose diet.

Abstract:

:Fructose-fed rats were more susceptible to peroxidative damage as measured by thiobarbituric acid reactive species. The concentrations of lipid peroxides, diene conjugates, lipofuscin and hydroperoxides were significantly higher. The levels of enzymic antioxidants such as vitamin C, vitamin E and glutathione and activities of antioxidant enzymes were significantly lower in fructose-fed rats. When these rats received taurine in drinking water, peroxidative damage was minimal in both plasma and liver. Taurine was effective in inducing the antioxidant potential in fructose-fed rats. Increased peroxidative damage in liver is likely to be associated with fructose dependent pathology, which could be reduced by taurine by enhancing the antioxidant potential.

journal_name

Indian J Exp Biol

authors

Nandhini AT,Balakrishnan SD,Anuradha CV

keywords:

subject

Has Abstract

pub_date

2002-09-01 00:00:00

pages

1016-9

issue

9

eissn

0019-5189

issn

0975-1009

journal_volume

40

pub_type

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