Abstract:
:Effect of oral administration of gossypol acetic acid (15 mg/kg/day) for 10 weeks, on certain enzymes, which may be taken as markers for the different stages of spermatogenesis, was studied in male albino rats. Gossypol produced a significant decrease in hyaluronidase and sorbitol dehydrogenase, while no change was observed in beta-glucuronidase and acid phosphatase. A significant increase in the total lactate dehydrogenase activity was observed in the testis. The possible significance of these findings is discussed.
journal_name
Indian J Exp Bioljournal_title
Indian journal of experimental biologyauthors
Nair IN,Bhiwgade DAsubject
Has Abstractpub_date
1989-12-01 00:00:00pages
1087-9issue
12eissn
0019-5189issn
0975-1009journal_volume
27pub_type
杂志文章abstract::Formulations (ointment, cream and gel) of aqueous extract of C. asiatica, when applied topically, thrice daily for 24 days on the open wounds in rats increased cellular proliferation and collagen synthesis at the wound site, as evidenced by increase in collagen content and tensile strength. The treated wounds epitheli...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:1998-06-01 00:00:00
abstract::According to Ayurvedic literature of Sri Lanka, roasted seeds of Artocarpus heterophyllus Lam. (Family: Moraceae) has aphrodisiac activity. However, some reproductively active young men in rural areas of Sri Lanka claim that consumption of these seeds few hours prior to coitus disrupts sexual function. Because of thes...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:2002-03-01 00:00:00
abstract::Extra pulmonary tuberculosis (EPTB) constitutes around 20% of all tuberculosis cases in India. Conventional methods are of limited use in diagnosing this form of the disease. Polymerase chain reaction (PCR) has emerged as a sensitive and specific tool for documenting the presence of Mycobacterium tuberculosis in clini...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:2009-06-01 00:00:00
abstract::Topical delivery of ibuprofen directly to the site of inflammation can overcome gastrointestinal side effects associated with its long term oral administration. The set of physicochemical properties necessary for optimum topical delivery of ibuprofen can be imparted by formation of its ester prodrugs. Various alkyl es...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:2001-03-01 00:00:00
abstract::Preventive role of lipistat against doxorubicin induced myocardial toxicity in rats has been reported. Cardiotoxicity was produced by doxorubicin administration (15 mg/kg for 2 weeks). Lipistat (350 mg/kg, orally) was administered as pretreatment for 2 weeks and then for 2 weeks alternated with doxorubicin. The genera...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:2009-01-01 00:00:00
abstract::Primary regenerants (1190) of a tall traditional salt tolerant rice cultivar pokkali were produced through in vitro culture from mature seed derived calli of fourth subculture. Out of 35000 SC2 regenerants, 26 promising lines with superior agronomic traits were chosen initially for evaluation. SC3 and SC4 generations ...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:2000-01-01 00:00:00
abstract::In vitro effects of various organophosphate pesticides (dimethoate, chlorpyrifos, ethion and monocrotophos) were studied on hemolysis, K+ leakage and lipid peroxidation in rat erythrocytes. All the four pesticides increased hemolysis and K+ leakage from erythrocytes, that was concentration and time dependent. On the c...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:2004-03-01 00:00:00
abstract::Effect of electrolytic lesion in vestibulo-cerebellar area of male Wistar rats was investigated on duodenal alkaline phosphatase (AP) activity. Histomorphological observations of brain indicated, that extensive lesion restricted to the wide area of nodule including ventral uvula, resulted in significant fall of AP act...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:1995-10-01 00:00:00
abstract::Effect of Swerchirin (1:8 dihydroxy 3:5 dimethoxy xanthone) isolated from hexane fraction of Swertia chirayita on the blood sugar level of healthy and streptozotocin treated rats was studied. Streptozotocin was administered in citrate buffer (pH-4.5) intravenously / 35 and 65 mg/kg body wt to Charles Foster strain alb...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:1991-07-01 00:00:00
abstract::Iron deficiency during pregnancy and lactation (35 mg iron/kg diet) produced a significant reduction in liver nonheme iron in dams as well as in fetus and young ones. The body, liver and brain weights of fetus, new-born, and developing pups remained unaffected. However, the body weight and PCV were reduced only in 21-...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:1990-05-01 00:00:00
abstract::Mowrah (M. latifolia) seeds yield 40-50% edible fat and the meal contains saponins besides protein and high level of carbohydrates. The toxicity of the meal was evaluated as it has a potential for use in animal feedstuffs. The meal was fed to young and adult rats at levels of 10 to 40% in diet. The animals showed mark...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:1996-01-01 00:00:00
abstract::Maize (Zea mays L. cv kanaujia) plants grown with Zn [10 (control), 0.1 (low) and 20 microM (high)], were investigated for concentration of antioxidants and activities of antioxidative enzymes in leaves. Young leaves of low Zn plants developed whitish-necrotic spots. Leaves of both low and high Zn plants showed decrea...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:2002-08-01 00:00:00
abstract::Orchidectomy caused a significant decrease in the concentration of ascorbic acid and ascorbic acid-2-sulphate in tissues while administration of testosterone to these animals reverses this effect. Concentration of ascorbic acid in liver in experimental groups correlates with the activity of L-qualano-lactone oxidase a...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:1994-07-01 00:00:00
abstract::The maturing goat epididymal spermatozoa were isolated from different segments of epididymis and these cells dispersed in a modified Ringer's solution, were incubated at 37 degrees C for 60 min to evaluate their autoagglutination efficacy. Distal corpus-epididymal spermatozoa specifically showed high order of head-to-...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:1992-11-01 00:00:00
abstract::Skin and tendon samples of male albino rat taken for analysis, on the 120th day of smoking showed that, compared to controls, the cigarette smoke exposed group showed an increase in tensile strength of both skin and tendon while extensibility of skin remained the same and that of the tendon increased. Thermal behaviou...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:1997-07-01 00:00:00
abstract::Multiple doses of H. spinosa were administered, ip once in a week for 4 weeks (20, 40 and 80 mg/kg body weight) and daily for one month (2, 4 and 8 mg/kg body weight). No alteration in biochemical parameters at low and moderate dose level of daily and low dose level of weekly treatment of petroleum ether extract was o...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:1996-12-01 00:00:00
abstract::Rats pre-administered with alpha-tocopherol (10 mgs/day) for 7 days afforded a significant protection at the tissue level against the lowering of superoxide dismutase and glutathione peroxidase, especially the selenium-dependent glutathione peroxidase. The protective action of alpha-tocopherol in the diethyldithiocarb...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:2007-05-01 00:00:00
abstract::Leukotrienes play a part in inflammatory response. The unique role of the enzyme 5-lipoxygenase (5-LOX) in the production of leukotrienes makes it a likely therapeutic target for inflammatory conditions like asthma, rheumatoid arthritis, psoriasis, and inflammatory bowel disease (IBD). The aim of the present study was...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:2004-07-01 00:00:00
abstract::Shoots of apple rootstocks raised in vitro were transferred to various rooting media to study the effect of different factors on root initiation and development. Various concentrations of indole-3-butyric acid (IBA) initiated rooting but maximum rooting percentage was found with 2.0 and 2.5 mg l(-1) of IBA in M7 and w...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:2007-09-01 00:00:00
abstract::The present study was undertaken to investigate the in vitro influence of mibefradil, a calcium channel blocker, and pinacidil, a potassium channel opener, on pregnant goat myometrial spontaneous rhythmic contractility and contractions induced with the agonist, oxytocin. Longitudinal strips from the distal region of u...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:2005-09-01 00:00:00
abstract::Getting higher yields of monoclonal antibody (MAb) is a problem in Hybridoma Technology which has two major bottlenecks--(a) poor yield of hybridized cells; and (b) low cellular productivity of MAb in culture. There are three ways of obtaining high MAb yield in vitro--(a) large scale culture of hybrid cells; (b) high ...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章,评审
doi:
更新日期:1998-02-01 00:00:00
abstract::The biodegradation of spent saline bottles, a low density polyethylene product (LDPE) by two selected Arthrobacter sp. under in vitro conditions is reported. Chemical and UV pretreatment play a vital role in enhancing the rate of biodegradation. Treated LDPE film exhibits a higher weight loss and density when compared...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:2012-07-01 00:00:00
abstract::A study to monitor marine pollution with reference to trace elements (Fe, Zn, Mn and Cu) on T. attenuata, commonly called as screw shell over a period of one year on the whole body and various organs, viz. digestive diverticula, foot, mantle and ovary was conducted from the sandy beach of Porto Novo Coast (Lat 11 degr...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:1999-11-01 00:00:00
abstract::Anther culture (AC) derived 160 doubled haploid (DH) families of an indica rice PTB 28 were field evaluated at Port Blair (lat 11 degrees.41'13.04"N; long 92 degrees 43'30.16"E), to assess the extent and range of induced variability among the androclones at segregating A2 generation and identify promising selectants f...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:2000-10-01 00:00:00
abstract::Frog plasma effectively hydrolysed the synthetic chromogenic substrates, H-D-Glu-Gly-Arg-p-nitroanilide (S-2444), benzoyl-Ile-Glu-Gly-Arg-p-nitroanilide (S-2222) and acetyl-Ile-Glu-Gly-Arg- p-nitroanilide (S-2423), all sensitive substrates for trypsin. Moderate hydrolytic activities was observed with H-D-Phe-Pip-Arg-p...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:1997-11-01 00:00:00
abstract::A bioactive compound with antibacterial activity was isolated and purified from the extract of leaves of sunflower, Helianthus annuus. The bioactive compound was characterized using 1H and 13C NMR. The compound induced auxin, gibberellins and cytokinin in Oryza sativa and Phaseolus mungo. It also showed activity again...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:2008-12-01 00:00:00
abstract::Oral administration of ethanol extract of N. sativa seeds (300 mg/kg body weight/day) to streptozotocin induced diabetic rats for 30 days significantly reduced the elevated levels of blood glucose, lipids, plasma insulin and improved altered levels of lipid peroxidation products (TBARS and hydroperoxides) and antioxid...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:2006-09-01 00:00:00
abstract::The possibility of stimulation of C-reactive protein (CRP) due to inflammation and necrosis caused by cadmium was investigated. Cadmium injection (less than 3 mg/kg body weight) in white rat was found to be associated with the appearance of CRP in liver cytosol after 8 hr and in serum after 18 hr of injection. Althoug...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:1989-12-01 00:00:00
abstract::Around 150 lipase producing bacterial isolates were screened from the local soils enriched with oil. Citrobacrer freundii IIT-BT L139, an isolated microbial strain, produced lipase that had high activity (8.8 U/ml) at pH 9.0 and 40 degrees C. The 16S rDNA phylogenetic studies showed that Citrobacter freundii belongs t...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:2006-06-01 00:00:00
abstract::Diabetes induced by streptozotocin (50 mg/kg body wt, i.p.) in the rats substantially increased the plasma glucose and malondialdehyde levels along with corresponding decrease in the antioxidants levels. Supplementation of vitamin E (200 mg/kg body wt., ip) for 5 weeks resulted in non-significant decrease in the blood...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:2005-02-01 00:00:00