In vitro antiviral activity of plant extracts on goatpox virus replication.

Abstract:

:Four plants having known medicinal properties were screened for inhibition of goatpox virus (GTPV) replication in vitro. Of the 4 plants, extract of Acacia arabica (Babul) and Eugenia jambolana (Jamun) leaves had inhibition (%) 99.70 and 99.92 at their maximum non toxic concentrations, 99.93 +/- 0.38 and 1999.73 +/- 0.50 microg/ml, respectively in all cytopathic effect (CPE) inhibition assays. Inhibition of GTPV virus replication was further confirmed by PCR and SYBR Green based quantitative real-time QPCR assays specific for GTPV. Results indicated that the extract of Acacia arabica and Eugenia jambolana leaves inhibited GTPV replication in vitro.

journal_name

Indian J Exp Biol

authors

Bhanuprakash V,Hosamani M,Balamurugan V,Gandhale P,Naresh R,Swarup D,Singh RK

subject

Has Abstract

pub_date

2008-02-01 00:00:00

pages

120-7

issue

2

eissn

0019-5189

issn

0975-1009

journal_volume

46

pub_type

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