Abstract:
:Lead (100 ppm) was given in doubly deionised water for 30 days to one group of rats. The other groups received lead along with exogenous antioxidants like vitamin E (50 IU/kg), vitamin C (800 mg/kg) or Spirulina (1500 mg/kg) in food for a similar period. Levels of lipid peroxidation products such as malondialdehyde, conjugated diene and hydroperoxide were measured in liver, lung and kidney of treated rats. In lead treated animals there was a significant increase in the levels of these lipid peroxidative products. Administration of exogenous antioxidants in the lead treated animals reduced the levels of malondialdehyde, conjugated diene and hydroperoxide. It indicated that vitamin E, vitamin C and Spirulina had significant (P < 0.001) antioxidant activity thereby protecting the animals from lead induced toxicity.
journal_name
Indian J Exp Bioljournal_title
Indian journal of experimental biologyauthors
Upasani CD,Khera A,Balaraman Rkeywords:
subject
Has Abstractpub_date
2001-01-01 00:00:00pages
70-4issue
1eissn
0019-5189issn
0975-1009journal_volume
39pub_type
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