Abstract:
:Administration of testosterone propionate (TP; 1 mg/kg body weight/day; im, for 30 days) to mature male bonnet monkeys, decreased total lipids, glyceride glycerol and cholesterol concentrations in hepatic tissue. The decrease in glyceride glycerol was due to decrease in monoacyl and triacyl glycerol. Both, free and esterified cholesterol were decreased after testosterone administration. Eventhough, total phospholipid was not significantly altered, phosphatidylserine and cardiolipin were increased, due to testosterone administration. Testosterone inhibited NADP-isocitrate dehydrogenase activity in liver. The findings suggest that testosterone acts as a lipolytic hormone and its action may be direct through its specific receptors in liver.
journal_name
Indian J Exp Bioljournal_title
Indian journal of experimental biologyauthors
Jeyaraj DA,Govindarajulu Psubject
Has Abstractpub_date
1991-12-01 00:00:00pages
1140-1issue
12eissn
0019-5189issn
0975-1009journal_volume
29pub_type
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