Comparative effects of prenatal and postnatal undernutrition on learning and memory in rats.

Abstract:

:Effects of pre- and post-natal undernutrition on learning and memory parameters were studied in albino rats. Prenatal undernutrition was induced in rat pups by restricting the mother's diet by 50% during the entire gestation period, whereas postnatal undernutrition was induced in rat pups by restriction of their diet by rotating them between lactating and non-lactating maternalised females for 12 hr each day during suckling period from 2nd day to 18th day after birth. At 2.5 to 3 months of age all the rat offsprings were subjected to (i) original and reversal discrimination learning, (ii) passive avoidance, and (iii) active avoidance and its retention tests. The results indicate that both pre- and post-natal undernutrition in rat pups caused significant deficits in original and reversal discrimination learning, retention of passive avoidance after one week retention interval, and retention of active of avoidance learning. However, both pre- and post-natal undernutrition did not show significant effect on acquisition of active avoidance and retention of passive avoidance after 24 hr retention interval.

journal_name

Indian J Exp Biol

authors

Jaiswal AK,Upadhyay SN,Satyan KS,Bhattacharya SK

keywords:

subject

Has Abstract

pub_date

1999-01-01 00:00:00

pages

17-22

issue

1

eissn

0019-5189

issn

0975-1009

journal_volume

37

pub_type

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