Effect of fatty acid binding proteins on developing human placental malate dehydrogenase activity.

Abstract:

:Role of fatty acid binding proteins (FABPs) in modulating inhibition of human placental malate dehydrogenase by palmitoyl-CoA and oleate has been studied. Activity of human placental cytosolic malate dehydrogenase is detected throughout the gestation, showing a peak at midgestation (20-25 weeks). Inhibition (50%) of the enzyme activity is obtained by 20 microM palmitoyl-CoA or 35 microM oleate. FABPs enhance the activity of malate dehydrogenase in absence of palmitoyl-CoA or oleate and also protect against palmitoyl-CoA or oleate inhibition. Such a modulatory effect of FABP may be due to the binding of long chain fatty acyl-CoA or fatty acid rather than a direct effect of FABPs on the enzyme.

journal_name

Indian J Exp Biol

authors

Bandyopadhyay AK,Das T,Sa G,Mukherjea M

subject

Has Abstract

pub_date

1994-11-01 00:00:00

pages

800-3

issue

11

eissn

0019-5189

issn

0975-1009

journal_volume

32

pub_type

杂志文章
  • Measurement of creatinine by Jaffe's reaction--determination of concentration of sodium hydroxide required for maximum color development in standard, urine and protein free filtrate of serum.

    abstract::Creatinine in serum or urine is determined by Jaffe's reaction where creatinine produces quantitatively an orange color with picric acid in alkaline medium. After allowing an incubation time of 15 min at room temperature for color development the color is measured at 520 nm. Without taking into consideration the acidi...

    journal_title:Indian journal of experimental biology

    pub_type: 杂志文章

    doi:

    authors: Toora BD,Rajagopal G

    更新日期:2002-03-01 00:00:00

  • Hypoglycemic effect of methanol extract of Phyllanthus amarus Schum & Thonn on alloxan induced diabetes mellitus in rats and its relation with antioxidant potential.

    abstract::Methanolic extract of P. amarus was found to have potential anti-oxidant activity as it could inhibit lipid peroxidation, and scavenge hydroxyl and superoxide radicals in vitro. The amount required for 50% inhibition of lipid peroxide formation was 104 microg/ml and the concentrations needed to scavenge hydroxyl and s...

    journal_title:Indian journal of experimental biology

    pub_type: 杂志文章

    doi:

    authors: Raphael KR,Sabu MC,Kuttan R

    更新日期:2002-08-01 00:00:00

  • Alkyl ester prodrugs for improved topical delivery of ibuprofen.

    abstract::Topical delivery of ibuprofen directly to the site of inflammation can overcome gastrointestinal side effects associated with its long term oral administration. The set of physicochemical properties necessary for optimum topical delivery of ibuprofen can be imparted by formation of its ester prodrugs. Various alkyl es...

    journal_title:Indian journal of experimental biology

    pub_type: 杂志文章

    doi:

    authors: Bansal AK,Khar RK,Dubey R,Sharma AK

    更新日期:2001-03-01 00:00:00

  • Effect of tolmetin and its copper complex on wound healing.

    abstract::Dose matched comparison between copper complex of tolmetin(Tol-Cu) and tolmetin(Tol) was carried out in male albino rats bearing either sutured incision, dead space or excision wounds. Results showed that Tol significantly decreased tesile strength of incision and dead space wound. This effect was totally reversed by ...

    journal_title:Indian journal of experimental biology

    pub_type: 杂志文章

    doi:

    authors: Somayaji SN,Jacob AP,Bairy KL

    更新日期:1995-03-01 00:00:00

  • Circadian features of carbohydrate metabolism in domestic fowls exposed to weekly 120 degree-shifts of synchronizer schedule.

    abstract::Effects of weekly 8 hr advance- or delay-shifts on the circadian rhythm of plasma glucose, liver glycogen and muscle glycogen in male domestic fowls, beginning at about 3 days of age, were examined. Circadian rhythm in the aforesaid indices of carbohydrate metabolism in control birds was also studied. Blood and tissue...

    journal_title:Indian journal of experimental biology

    pub_type: 杂志文章

    doi:

    authors: Saini SK,Pati AK

    更新日期:1992-02-01 00:00:00

  • Acidic and basic protein contents in Gastrocnemii and pectoralis muscles of chick under denervation and work-induced stress conditions.

    abstract::Biochemical estimation of acidic and basic proteins of chick gastrocnemii (G. externus, G. medius and G. internus) and pectoralis muscles has been done under normal, denervated and work stress conditions from 1-56 days of postnatal growth. The reciprocal relationship of the two protein groups is clearly established. I...

    journal_title:Indian journal of experimental biology

    pub_type: 杂志文章

    doi:

    authors: Sharma S,Malhotra RK

    更新日期:1992-05-01 00:00:00

  • Siderophores of halophilic archaea and their chemical characterization.

    abstract::Nine halophilic archaea viz., Halobacterium salinarum, Halobacterium sp.1, Halobacterium sp.2, Halobaculum sp., Halococcus saccharolyticus, Halorubrum saccharovorum, Haloterrigena turkmenica, Halogeometricum sp. and Natrialba sp. isolated from marine salterns around Bhavnagar coast were screened for siderophore produc...

    journal_title:Indian journal of experimental biology

    pub_type: 杂志文章

    doi:

    authors: Dave BP,Anshuman K,Hajela P

    更新日期:2006-04-01 00:00:00

  • Inhibition of mutagenicity of food-derived heterocyclic amines by sulforaphane--a constituent of broccoli.

    abstract::Sulforaphane, a constituent of broccoli was investigated for its antimutagenic potential against different classes of cooked food mutagens (heterocyclic amines). These include imidazoazaarenes such as 2-amino-3-methylimidazo[4,5-f]quinoline (IQ), 2-amino-3,4-dimethylimidazo[4,5-f]quinoline (MeIQ), 2-amino-3,8-dimethyl...

    journal_title:Indian journal of experimental biology

    pub_type: 杂志文章

    doi:

    authors: Shishu,Kaur IP

    更新日期:2003-03-01 00:00:00

  • Immunoreactive-FSH in human normal gastric mucosa.

    abstract::Using indirect immuno-peroxidase staining technique, localization of immunoreactive follicle-stimulating hormone (IR-FSH) is demonstrated in the cytoplasm of the epithelial cells of normal human stomach. In view of their triangular shape and central nucleus and their predominance in the intermediate glands of the gast...

    journal_title:Indian journal of experimental biology

    pub_type: 杂志文章

    doi:

    authors: Mandrekar PS,Sheth AR,Doctor VM,Zaveri JP,Sheth NA

    更新日期:1990-02-01 00:00:00

  • Potential application of beta-1, 3 glucanase from an environmental isolate of Pseudomonas aeruginosa MCCB 123 in fungal DNA extraction.

    abstract::Pseudomonas aeruginosa MCCB 123 was grown in a synthetic medium for beta-1,3 glucanase production. From the culture filtrate, beta-1,3 glucanase was purified with a molecular mass of 45 kDa. The enzyme was a metallozyme as its beta-1,3 glucanase activity got inhibited by the metal chelator EDTA. Optimum pH and tempera...

    journal_title:Indian journal of experimental biology

    pub_type: 杂志文章

    doi:

    authors: Jose D,Jayesh P,Gopinath P,Mohandas A,Singh IS

    更新日期:2014-01-01 00:00:00

  • Enhancement of gastrointestinal absorption of poorly water soluble drugs via lipid based systems.

    abstract::Development of knowledge on lipids has attracted the scientific community for the effective utilization of the natural and synthetic lipids. Bioavailability of poorly water soluble drugs from gastrointestinal tract (GIT) can be enhanced by formulating the drugs in lipid based formulations. This formulation can increas...

    journal_title:Indian journal of experimental biology

    pub_type: 杂志文章,评审

    doi:

    authors: Subramanian N,Ghosal SK

    更新日期:2004-11-01 00:00:00

  • Partial role of nitric oxide in infarct size limiting effect of quercetin and rutin against ischemia-reperfusion injury in normal and diabetic rats.

    abstract::Reperfusion injury is remarkable clinical issue that needs to be resolved as ischemia-reperfusion is a common phenomenon encountered in numerous clinical situations. The present communication report the involvement of nitric oxide (NO) in cardioprotection offered by flavonoids (rutin and quercetin) against myocardial ...

    journal_title:Indian journal of experimental biology

    pub_type: 杂志文章

    doi:

    authors: Challa SR,Akula A,Metla S,Gopal PN

    更新日期:2011-03-01 00:00:00

  • Antifungal activity and mode of action of saponins from Madhuca butyracea Macb.

    abstract::The antifungal activity of saponins isolated as a byproduct from the defatted cake of M. butyracea oil seed is reported. The inhibitory concentrations against plant pathogenic fungi ranged from 500 to 2000 ppm. Maximum sensitivity to saponins was shown by Penicillium expansum. Cephalosporium acrimonium, Helminthospori...

    journal_title:Indian journal of experimental biology

    pub_type: 杂志文章

    doi:

    authors: Lalitha T,Venkataraman LV

    更新日期:1991-06-01 00:00:00

  • Mechanism of nickel resistance in a cobalt-resistant wall-less mutant of Neurospora crassa (fz; sg; os-1).

    abstract::A cobalt-resistant wall-less mutant of N. crassa (Cor-sl) characterized previously was also found to be 3-fold more resistant to nickel when compared to the parent wall-less mutant (W-sl). The Cor-sl strain accumulates relatively lower amounts of nickel when compared to W-sl. Sub-cellular fractionation showed signific...

    journal_title:Indian journal of experimental biology

    pub_type: 杂志文章

    doi:

    authors: Rajyalaxmi RS,Sowjanya TN,Kiranmayi P,Mohan MP

    更新日期:2004-11-01 00:00:00

  • Circular form of regeneration in an unidentified species of land planarians, Bipalium sp.

    abstract::The communication describes an interesting and possibly novel finding regarding a species of land planarians (Bipalium sp.) from a high altitude of Himalayan range. The regeneration in Bipalium sp. is highly interesting and the process takes about a fortnight for the completion. Accumulation of numerous basophilic cel...

    journal_title:Indian journal of experimental biology

    pub_type: 杂志文章

    doi:

    authors: Patra BC,Aditya AK

    更新日期:2001-05-01 00:00:00

  • Vasoprotection by melatonin and quercetin in rats treated with cisplatin.

    abstract::Cisplatin-based chemotherapy has a variety of vascular side effects. The aim of the present study was to evaluate the beneficial effect of melatonin and cisplatin on the alterations in vascular reactivity and structure of cisplatin-treated rats. Phenylephrine (PHE) and KCl-caused concentration-dependent contractions o...

    journal_title:Indian journal of experimental biology

    pub_type: 杂志文章

    doi:

    authors: Atalik KE,Keleş B,Uyar Y,Dündar MA,Oz M,Esen HH

    更新日期:2010-12-01 00:00:00

  • 5-HT3 receptors in selective animal models of cognition.

    abstract::Role of 5-HT3 receptors in cholinergic hypofunctional models of cognitive impairment in the elevated plus maze model and a passive avoidance model is studied. Cognitive impairment was caused by scopolamine (1 mg/kg, ip) in mice and 5-HT3 ligands mCPBG (1 and 5 mg/kg, ip) and ondansetron (0.5 and 5 mg/kg, ip) were admi...

    journal_title:Indian journal of experimental biology

    pub_type: 杂志文章

    doi:

    authors: Sridhar N,Veeranjaneyulu A,Arulmozhi DK,Gupta CN,Babu RJ

    更新日期:2002-02-01 00:00:00

  • Biochemical effects of Nigella sativa L seeds in diabetic rats.

    abstract::Oral administration of ethanol extract of N. sativa seeds (300 mg/kg body weight/day) to streptozotocin induced diabetic rats for 30 days significantly reduced the elevated levels of blood glucose, lipids, plasma insulin and improved altered levels of lipid peroxidation products (TBARS and hydroperoxides) and antioxid...

    journal_title:Indian journal of experimental biology

    pub_type: 杂志文章

    doi:

    authors: Kaleem M,Kirmani D,Asif M,Ahmed Q,Bano B

    更新日期:2006-09-01 00:00:00

  • Activation of macrophages with N-formyl-methionyl-leucyl-phenylalanine: involvement of protein kinase C and tyrosine kinase.

    abstract::N-formyl-methionyl-leucyl-phenylalanine (fMLP) a potent chemotactic peptide stimulates immune responses by activating macrophages and other cells of the immune system. The present study reports inhibition of fMLP-induced activation of murine peritoneal and P388D-1 macrophage cell line by protein kinase C (PKC) inhibit...

    journal_title:Indian journal of experimental biology

    pub_type: 杂志文章

    doi:

    authors: Shrivastava A

    更新日期:2007-09-01 00:00:00

  • Changes in rubisco content in relation to saccharides accumulation in wheat leaves during day.

    abstract::Two wheat varieties, T. durum (HD 4502) and T. aestivum (Kalyansona) were examined for photosynthesis rate and contents of sugars and rubisco protein in the flag leaf, at forenoon and afternoon at anthesis stage. A decrease in photosynthesis rate was observed in the afternoon compared to forenoon in both the varieties...

    journal_title:Indian journal of experimental biology

    pub_type: 杂志文章

    doi:

    authors: Rafique S,Sharma-Natu P,Ghildiyal MC

    更新日期:2001-11-01 00:00:00

  • Cardioprotective effect of lipistat against doxorubicin induced myocardial toxicity in albino rats.

    abstract::Preventive role of lipistat against doxorubicin induced myocardial toxicity in rats has been reported. Cardiotoxicity was produced by doxorubicin administration (15 mg/kg for 2 weeks). Lipistat (350 mg/kg, orally) was administered as pretreatment for 2 weeks and then for 2 weeks alternated with doxorubicin. The genera...

    journal_title:Indian journal of experimental biology

    pub_type: 杂志文章

    doi:

    authors: Koti BC,Vishwanathswamy AH,Wagawade J,Thippeswamy AH

    更新日期:2009-01-01 00:00:00

  • Activity of glutathione related enzymes and ovarian steroid hormones in different sizes of follicles from goat and sheep ovary of different reproductive stages.

    abstract::The investigations on enzymes related to glutathione like glutathione-S-transferase (GST) and glutathione peroxidase (GSH-Px) have been carried out mostly in human and rat ovaries, however the studies on these enzymes in ruminants are relatively absent. In the present study the changes in the activity of these enzymes...

    journal_title:Indian journal of experimental biology

    pub_type: 杂志文章

    doi:

    authors: Sesh PS,Singh D,Sharma MK,Pandey RS

    更新日期:2001-11-01 00:00:00

  • Effect of antioxidants on adenosine triphosphatase activity of brain and heart in male mice during ageing.

    abstract::The present study deals with the effect of butylated hydroxy anisole, propyl gallate and alpha-tocopherol on ATPase activity of brain and heart in ageing male mice. The activity of both the tissues significantly increased during pre-reproductive and reproductive phases. However, during the post-reproductive phase, ATP...

    journal_title:Indian journal of experimental biology

    pub_type: 杂志文章

    doi:

    authors: Garg SK,Khanna SC,Sharma SP

    更新日期:1992-04-01 00:00:00

  • Angiotensin converting enzyme activity in female reproductive tract of domestic fowl (Gallus domesticus) and its interactions with semen.

    abstract::Presence of angiotensin converting enzyme (ACE, EC 3.4.15.1) in female reproductive tract and its interaction with semen has been investigated in domestic fowl. Higher activity of ACE was detected in homogenates of infundibulum region followed by magnum and relatively low level was noticed in rest of the parts of the ...

    journal_title:Indian journal of experimental biology

    pub_type: 杂志文章

    doi:

    authors: Mohan J,Moudgal RP,Singh NB

    更新日期:1993-07-01 00:00:00

  • Radioprotection of chick thymus by vitamin E.

    abstract::One day and 7 days old male white leghorn chicks were administered vitamin E prior to their exposure to sublethal dose (2.25 Gy) of gamma radiation from 60C source. The results show that vitamin E helps in faster recovery of damage in chick thymus caused by irradiation. ...

    journal_title:Indian journal of experimental biology

    pub_type: 杂志文章

    doi:

    authors: Rana K,Sood A,Malhotra N

    更新日期:1993-10-01 00:00:00

  • Immunomodulation of macrophages by radio-detoxified lipopolysaccharide of Salmonella typhimurium.

    abstract::Lipopolysaccharide (LPS) and ratio-detoxified LPS (Rd-LPS) from Salmonella typhimurium were analysed for their ability to stimulate murine peritoneal exudate cells (PEC) and macrophages. Rd-LPS induced much more inflammatory response as compared to LPS. PEC numbers/mouse obtained were significantly higher (3-fold) in ...

    journal_title:Indian journal of experimental biology

    pub_type: 杂志文章

    doi:

    authors: Naidu MD,Chander R

    更新日期:1999-03-01 00:00:00

  • Latitudinal variation in eclosion rhythm among strains of Drosophila ananassae.

    abstract::Eclosion rhythm parameters of D. ananassae strains originating between 8 degrees-34 degrees N were highly variable and latitude dependent. In the field under naturally fluctuating light intensity, temperature and R.H., the amplitude of the rhythm was high and the eclosion gate was narrow; however, under the naturally ...

    journal_title:Indian journal of experimental biology

    pub_type: 杂志文章

    doi:

    authors: Joshi DS,Gore AP

    更新日期:1999-07-01 00:00:00

  • Hypersensitivity responses to Staphylococcus aureus infections in rabbits. An experimental study.

    abstract::Repeated weekly infections with S aureus, of bovine mammary origin, for three times evoked an immediate and a delayed type hypersensitivity in rabbits. The skin responses at 6 hr were characterized by oedema, haemorrhages and infiltration of polymorphonuclear cells. While at 24 hr it was dominated by mononuclear cells...

    journal_title:Indian journal of experimental biology

    pub_type: 杂志文章

    doi:

    authors: Varshney JP,Kapur MP,Sadana JR

    更新日期:1991-01-01 00:00:00

  • The lld mutation in Pisum sativum used as a genetic tool to discern the plant leaflet/leaf developmental process.

    abstract::Leaves of P. sativum the double mutant genotype tendril-less (tl) leaflet-development (lld), due to the action of lld mutation, produce many leaflets that are aborted at different stages of development. Morphological, vein pattern and histological observations showed that aborted leaflets became cup/bell/trumpet (cup)...

    journal_title:Indian journal of experimental biology

    pub_type: 杂志文章

    doi:

    authors: Sharma V,Tripathi BN,Kumar S

    更新日期:2013-06-01 00:00:00

  • Treatment of waste gas containing low concentration of dimethyl sulphide in a high performance biotrickling filter.

    abstract::A bench-scale biotrickling filter was operated in the laboratory for the treatment of dimethyl sulphide (DMS). The biotrickling filter was packed with pre-sterilized polyurethane foam and seeded with biomass developed from garden soil enriched with DMS. The biotrickling filter was operated for the generation of proces...

    journal_title:Indian journal of experimental biology

    pub_type: 杂志文章

    doi:

    authors: Giri BS,Juwarkar A,Mudliar SN,Pandey RA

    更新日期:2013-11-01 00:00:00