Abstract：
:Petroleum ether (PE), benzene (BE), chloroform (CE), acetone (AE) and ethanolic (EE) extracts (50-200 or 200 mg/kg, i.p. or 200 mg/kg, p.o.) of dried Abies pindrow leaves, given 30-45 min before showed significant anti-inflammatory (both against acute and sub-acute models), analgesic, barbiturate hypnosis potentiation and anti-ulcerogenic acitivities in rats. All the extracts except EE decreased swim stress immobility in mice indicating some degree of anti-depressant activity. Only PE exhibited hypotension in dogs blocked by atropine. Chemically, extracts showed the presence of glycosides, steroids, terpenoids and flavonoids. They had no anti-bacterial effect. However, toxicity studies indicated that the extracts had an extended safety index. The investigations are consonant with some of the uses of this plant in Ayurveda.
journal_name
Indian J Exp Bioljournal_title
Indian journal of experimental biologyauthors
Singh RK,Nath G,Goel RK,Bhattacharya SKsubject
Has Abstractpub_date
1998-02-01 00:00:00pages
187-91issue
2eissn
0019-5189issn
0975-1009journal_volume
36pub_type
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pub_type： 杂志文章,评审
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journal_title：Indian journal of experimental biology
pub_type： 杂志文章,评审
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