Abstract:
:Mouse liver was exposed in vivo to a continuous and unfocussed ultrasound of 875 KHz at 5, 10 or 15 W/cm2 for 300 sec spread over five days and excised on day 0, 1, 5 and 10 for studying the changes in Na+ and K+ reserves and Na-K-ATPase activity. At 5 and 10 W intensities the change in ionic concentrations and Na-K-ATPase activity were almost in linear. At 15 W intensity the loss of both the ions and suppression of Na-K-ATPase indicated the damage of hepatic tissue caused by high intensity ultrasound. By day 10, all the animals of three exposures showed a normal ionic concentration with an optimum Na-K-ATPase activity in liver indicating the recovery process. The results indicate that ultrasound induces permeability changes in a glandular tissue exposed in vivo.
journal_name
Indian J Exp Bioljournal_title
Indian journal of experimental biologyauthors
Varma BM,Nath BS,Kumar RPsubject
Has Abstractpub_date
1994-10-01 00:00:00pages
698-701issue
10eissn
0019-5189issn
0975-1009journal_volume
32pub_type
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