Changes in Na and K ions in mouse liver following in vivo exposure to ultrasound.

Abstract:

:Mouse liver was exposed in vivo to a continuous and unfocussed ultrasound of 875 KHz at 5, 10 or 15 W/cm2 for 300 sec spread over five days and excised on day 0, 1, 5 and 10 for studying the changes in Na+ and K+ reserves and Na-K-ATPase activity. At 5 and 10 W intensities the change in ionic concentrations and Na-K-ATPase activity were almost in linear. At 15 W intensity the loss of both the ions and suppression of Na-K-ATPase indicated the damage of hepatic tissue caused by high intensity ultrasound. By day 10, all the animals of three exposures showed a normal ionic concentration with an optimum Na-K-ATPase activity in liver indicating the recovery process. The results indicate that ultrasound induces permeability changes in a glandular tissue exposed in vivo.

journal_name

Indian J Exp Biol

authors

Varma BM,Nath BS,Kumar RP

subject

Has Abstract

pub_date

1994-10-01 00:00:00

pages

698-701

issue

10

eissn

0019-5189

issn

0975-1009

journal_volume

32

pub_type

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