Abstract：
:Oral pretreatment of rats with G. cambogia fruit extract (1 g/kg body weight/day at interval of 7 and 15 days) protected gastric mucosa against HCl-ethanol induced damage by decreasing the volume and acidity of gastric juice. Increased lipid peroxidation, decreased activity of antioxidant enzymes, altered levels of protein and glycoproteins in the ulcerated mucosa, and gastric juice were maintained at near normal levels in G. cambogia pretreated rats. The results suggest the anti-ulcer activity of G. cambogia by virtue of its ability to decrease acidity and increase mucosal defense.
journal_name
Indian J Exp Bioljournal_title
Indian journal of experimental biologyauthors
Mahendran P,Sabitha KE,Devi CSkeywords:
subject
Has Abstractpub_date
2002-01-01 00:00:00pages
58-62issue
1eissn
0019-5189issn
0975-1009journal_volume
40pub_type
杂志文章abstract：:In view of the contribution of iron deposition in the oxidative pathologic process of liver disease, the potential of 70% methanolic extract of C. cajan leaf (CLME) towards antioxidative protection against iron-overload-induced liver damage in mice has been investigated. DPPH radical scavenging and protection of Fento...
journal_title：Indian journal of experimental biology
pub_type： 杂志文章
doi：
更新日期：2013-02-01 00:00:00
abstract：:Primary regenerants (1190) of a tall traditional salt tolerant rice cultivar pokkali were produced through in vitro culture from mature seed derived calli of fourth subculture. Out of 35000 SC2 regenerants, 26 promising lines with superior agronomic traits were chosen initially for evaluation. SC3 and SC4 generations ...
journal_title：Indian journal of experimental biology
pub_type： 杂志文章
doi：
更新日期：2000-01-01 00:00:00
abstract：:Convolvulus pluricaulis is an indigenous plant commonly mentioned in Ayurveda, an ancient system of Indian medicine, as a rasayana which is mainly advocated for use in rejuvenation therapy. The present study was conducted to evaluate the potential anti-ulcerogenic effect of juice of fresh whole plants of C. pluricauli...
journal_title：Indian journal of experimental biology
pub_type： 杂志文章
doi：
更新日期：2001-04-01 00:00:00
abstract：:In order to find out the effect of chronic ethanol administration on testicular antioxidant system and steroidogenic enzyme activity, male rats fed with ethanol 1.6g/kg body weight per day for four weeks were studied. Besides a drastic reduction in body and testis weight, there was decrease in ascorbic acid, reduced g...
journal_title：Indian journal of experimental biology
pub_type： 杂志文章
doi：
更新日期：2005-05-01 00:00:00
abstract：:Calcium calmodulin dependent protein ser/thr phosphatase, also referred to as protein phosphatase 2B (PP2B), is rich in neural tissue, and plays an important role in the overall function of the nervous system. Routinely phosphatase assay employs, para-Nitrophenlylphosphate (p-NPP), as a substrate, is also extended to ...
journal_title：Indian journal of experimental biology
pub_type： 杂志文章
doi：
更新日期：2014-02-01 00:00:00
abstract：:Thiram was administered to male rats through gavage at doses 5, 10 and 25 mg/kg/day for 180 and 360 days. Thiram has caused marginal increase in the relative weight of testes and epididymis and decrease in the weight of seminal vesicle and prostate. Marked degenerative changes were observed in seminiferous tubules tog...
journal_title：Indian journal of experimental biology
pub_type： 杂志文章
doi：
更新日期：1998-04-01 00:00:00
abstract：:The effects of sub-chronic doses of malathion exposure on humoral and cell-mediated immune (CMI) responses were studied in male albino mice, rats and rabbits using sheep red blood cells (SRBC), tetanus toxoid and ovalbumin as antigens. The humoral immune response was assessed by estimating serum immunoglobulin (IgM an...
journal_title：Indian journal of experimental biology
pub_type： 杂志文章
doi：
更新日期：1998-03-01 00:00:00
abstract：:The toxic effect of dried berries powder of P. cubeba, dried fruit powder of P. longum and T. terrestris singly as well as in combination [binary (1:1) and tertiary (1:1:1)] were studied against snail L. exustus. Toxicity of these plant products were time and concentration dependent. Ethanol extracts of these plants w...
journal_title：Indian journal of experimental biology
pub_type： 杂志文章
doi：
更新日期：2009-08-01 00:00:00
abstract：:"Triphala", the Ayurvedic wonder is used traditionally for the treatment of different types of diseases since antiquity. The hydroalcoholic extracts of the three components of Triphala powder demonstrated varying degrees of strain specific antibacterial activity against multidrug-resistant uropathogenic bacteria. Term...
journal_title：Indian journal of experimental biology
pub_type： 杂志文章
doi：
更新日期：2013-09-01 00:00:00
abstract：:The present study is planned to assess the diagnostic relevance of silver stained nucleolar organizer regions (NORs) in discriminating benign from malignant lesions of the breast and to ascertain the interobserver variability in the enumeration of AgNOR counts. Forty four specimens of benign and malignant breast tissu...
journal_title：Indian journal of experimental biology
pub_type： 杂志文章
doi：
更新日期：1995-10-01 00:00:00
abstract：:In the present study, antibacterial activity of aqueous and organic extracts of Psidium guajava leaves was evaluated against multidrug resistant (MDR) clinical isolates of Staphylococcus aureus strains collected from hospitals in northern (Malabar region) Kerala. The strains which exhibited resistance against all the ...
journal_title：Indian journal of experimental biology
pub_type： 杂志文章
doi：
更新日期：2008-01-01 00:00:00
abstract：:EHb-a herbo-mineral formulations of iron (ferrous form) produced a significantly higher and dose dependent increase in the haemoglobin level, as compared to Fefol (a non-complex-chelated iron preparation). Also, EHb did not produce any overt toxicity or gastric irritation at these dose levels. The results suggest that...
journal_title：Indian journal of experimental biology
pub_type： 杂志文章
doi：
更新日期：2001-07-01 00:00:00
abstract：:Binding of alpha-, beta-, gamma-hexachlorocyclohexane, p,p'-DDT and p,p'-DDE with bovine serum albumin (BSA) and locust brain homogenate was studied. Binding affinities of pesticides were higher for the locust brain homogenates than for BSA. Results of uptake by isolated locust brain revealed higher uptake of gamma-HC...
journal_title：Indian journal of experimental biology
pub_type： 杂志文章
doi：
更新日期：1992-09-01 00:00:00
abstract：:Breast cancer is a common malignancy in women all over the world and novel therapeutic approaches are required for the treatment of patients who become refractory to conventional therapies. Thyroid cancer is being treated successfully with radioiodine since many years. The iodide is transported inside the thyroid epit...
journal_title：Indian journal of experimental biology
pub_type： 杂志文章
doi：
更新日期：2011-06-01 00:00:00
abstract：:Recognition of Nitric oxide (NO) as the chemical entity of endothelium-derived relaxing factor (EDRF) has renewed the interest of the scientific community in the last decade. The outcome of research the world over is that the dreaded environmental pollutant is found to be a fundamental physiological mediator and effec...
journal_title：Indian journal of experimental biology
pub_type： 杂志文章,评审
doi：
更新日期：2000-03-01 00:00:00
abstract：:Cheek gland secretions from sexually mature and reproductively active male and female laboratory rats (Wister strain), Rattus norvegicus albinus were analysed by gas chromatography/mass spectroscopy. Alkanes, aliphatic acids esters and alcohols were identified in the secretions. Cheek gland preparation from males cont...
journal_title：Indian journal of experimental biology
pub_type： 杂志文章
doi：
更新日期：2001-09-01 00:00:00
abstract：:The present study was undertaken to evaluate the role of propofol in altering pentylenetetrazol induced seizure threshold in rats. Total 42 Wistar rats were used to evaluate different parameters (onset of action, duration of seizure, seizure severity score and number of seizure) following propofol injection. The prese...
journal_title：Indian journal of experimental biology
pub_type： 杂志文章
doi：
更新日期：2008-03-01 00:00:00
abstract：:A bioactive compound with antibacterial activity was isolated and purified from the extract of leaves of sunflower, Helianthus annuus. The bioactive compound was characterized using 1H and 13C NMR. The compound induced auxin, gibberellins and cytokinin in Oryza sativa and Phaseolus mungo. It also showed activity again...
journal_title：Indian journal of experimental biology
pub_type： 杂志文章
doi：
更新日期：2008-12-01 00:00:00
abstract：:Effect of electrolytic lesion in vestibulo-cerebellar area of male Wistar rats was investigated on duodenal alkaline phosphatase (AP) activity. Histomorphological observations of brain indicated, that extensive lesion restricted to the wide area of nodule including ventral uvula, resulted in significant fall of AP act...
journal_title：Indian journal of experimental biology
pub_type： 杂志文章
doi：
更新日期：1995-10-01 00:00:00
abstract：:Di-n-butyl phthalate (DBP) was administered to adult male rats by gavage at the doses of 250, 500 and 1000 mg/kg body weight/day for 15 days. A significant decrease in epididymal spermatozoa counts was observed at 500 and 1000 mg/kg doses of DBP. The activity of sorbitol dehydrogenase was found to be significantly dec...
journal_title：Indian journal of experimental biology
pub_type： 杂志文章
doi：
更新日期：1990-01-01 00:00:00
abstract：:Adult mice weighing 20 g, divided into 5 groups, were immunised with single and three cycle cryodestroyed ascites fibrosarcoma cells using different modes of immunisation with respect to dose and administration frequency. Survival against subsequent challenge with the same tumour cells and immune response given by leu...
journal_title：Indian journal of experimental biology
pub_type： 杂志文章
doi：
更新日期：1990-11-01 00:00:00
abstract：:A simple dot-immunobinding assay (Dot-Iba) in nitrocellulose paper was developed for the detection of specific IgG antibody to Mycobacterium tuberculosis antigen 5 and mycobacterial antigen in cerebrospinal fluid of patients with tuberculous meningitis (TBM). The assay gave 77.1% sensitivity for the detection of IgG a...
journal_title：Indian journal of experimental biology
pub_type： 杂志文章
doi：
更新日期：1991-05-01 00:00:00
abstract：:The xanthine oxidoreductase (XOR) system which consists of xanthine dehydrogenase (XDH) and xathine oxidase (XO), is one of the major sources of free radicals in biological systems. The XOR system is pre-dominantly present as XDH in normal tissues and converts into the free radical generating XO-form in the damaged ti...
journal_title：Indian journal of experimental biology
pub_type： 杂志文章,评审
doi：
更新日期：2003-02-01 00:00:00
abstract：:Serum corticosterone excess was induced by the administration of corticosterone acetate to adrenal intact rats. Different lipid classes were studied in unwashed and washed (epididymal sperm and fluid free) caput and cauda epididymides. The unwashed caput epididymidis registered a significant decrease in total lipid, c...
journal_title：Indian journal of experimental biology
pub_type： 杂志文章
doi：
更新日期：1989-08-01 00:00:00
abstract：:Dicarboxylic acids and a few amino acids were found to support mitochondrial phosphorylation in A. ceylanicum. Anaerobiasis markedly reduced this activity. Maximum effect was observed on succinate supported phosphorylation which in anaerobic atmosphere yielded only 2% ATP compared to that in the presence of air. Known...
journal_title：Indian journal of experimental biology
pub_type： 杂志文章
doi：
更新日期：1990-06-01 00:00:00
abstract：:Effect of pulse treatments of cordycepin, an analog of adenosine, on S and G2 phases of the cell cycle of the mitotically synchronous plasmodia of Physarum polycephalum has been studied. Various concentrations of the drug (50-200 micrograms ml-1) were found to be effective in delaying mitosis by several hours in both ...
journal_title：Indian journal of experimental biology
pub_type： 杂志文章
doi：
更新日期：1991-09-01 00:00:00
abstract：:Capsaicin exerts a stabilizing effect on erythrocytes making them more resistant to lysis under hypotonic stress. The protective action of capsaicin on osmotic fragility (OF) was not receptor mediated since no dose responsive effect was observed. The results suggest that this protective effect of capsaicin on OF is du...
journal_title：Indian journal of experimental biology
pub_type： 杂志文章
doi：
更新日期：1999-08-01 00:00:00
abstract：:During reproductive life in the female, there is a continuous flow of growth, maturation and demise of ovarian follicles, unless pregnancy occurs. Although ovarian function is primarily controlled by the hypothalamus-pituitary-axis, there is no doubt that a hormonal microenvironment specific for each individual follic...
journal_title：Indian journal of experimental biology
pub_type： 杂志文章,评审
doi：
更新日期：2003-07-01 00:00:00
abstract：:Diseases like tropical ataxic neuropathy and endemic goitre have been reported to have definite correlation with a chronic ingestion of cassava (Manihot esculenta Crantz). The toxicity of cassava has been attributed to its two cyanogenic glycosides, linamarin and lotaustralin. In this study, an attempt has been made t...
journal_title：Indian journal of experimental biology
pub_type： 杂志文章
doi：
更新日期：1989-06-01 00:00:00
abstract：:Acute single dose administration of lanthanum chloride (250 mg/kg body wt, ip) to chicks have been found to alter the levels of enzymes of the antioxidant defence system of chick renal cortex fractions. Such changes involved significant decrease in activities of glucose-6-phosphate dehydrogenase, glutathione reductase...
journal_title：Indian journal of experimental biology
pub_type： 杂志文章
doi：
更新日期：1992-12-01 00:00:00
