Abstract:
:Acute single dose administration of lanthanum chloride (250 mg/kg body wt, ip) to chicks have been found to alter the levels of enzymes of the antioxidant defence system of chick renal cortex fractions. Such changes involved significant decrease in activities of glucose-6-phosphate dehydrogenase, glutathione reductase, glutathione peroxidase and catalase of kidney epithelial cells. However glutathione-S-transferase activity was not altered. Glutathione and total thiol contents were decreased while lipoperoxidative reactions in kidney-cortex was significantly enhanced. The data indicate that amelioration of lanthanum toxicity condition by methionine supplementation may be due to the methionine serving as a precursor of glutathione.
journal_name
Indian J Exp Bioljournal_title
Indian journal of experimental biologyauthors
Maulik G,Ghosh N,Sengupta T,Chattopadhyay D,Chakraborty AK,Chatterjee GCkeywords:
subject
Has Abstractpub_date
1992-12-01 00:00:00pages
1166-9issue
12eissn
0019-5189issn
0975-1009journal_volume
30pub_type
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