Curative effect of methionine on certain enzymes of chick kidney cortex under lanthanum toxicity situation.

Abstract:

:Acute single dose administration of lanthanum chloride (250 mg/kg body wt, ip) to chicks have been found to alter the levels of enzymes of the antioxidant defence system of chick renal cortex fractions. Such changes involved significant decrease in activities of glucose-6-phosphate dehydrogenase, glutathione reductase, glutathione peroxidase and catalase of kidney epithelial cells. However glutathione-S-transferase activity was not altered. Glutathione and total thiol contents were decreased while lipoperoxidative reactions in kidney-cortex was significantly enhanced. The data indicate that amelioration of lanthanum toxicity condition by methionine supplementation may be due to the methionine serving as a precursor of glutathione.

journal_name

Indian J Exp Biol

authors

Maulik G,Ghosh N,Sengupta T,Chattopadhyay D,Chakraborty AK,Chatterjee GC

keywords:

subject

Has Abstract

pub_date

1992-12-01 00:00:00

pages

1166-9

issue

12

eissn

0019-5189

issn

0975-1009

journal_volume

30

pub_type

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