Abstract:
:Natural Killer activity assessed by 51Cr release assay from K-562 cells showed detectable activity from 5th day after tumour transplantation, reaching a peak on 12th day and thereafter showing a gradual decline in the activity. Antibody dependent cell mediated cytotoxicity estimated by 51Cr labelled sheep red blood cells anti SRBC system demonstrated a peak activity on 5th day. Cytotoxic T lymphocyte activity detected by 51Cr release of Dalton's lymphoma ascites target cells showed a peak on 10th day. Antibody complement mediated cytotoxicity revealed a similar pattern as natural killer cell activity.
journal_name
Indian J Exp Bioljournal_title
Indian journal of experimental biologyauthors
Suresh K,Nirmala K,Kuruvilla K,Vasudevan DMsubject
Has Abstractpub_date
1989-06-01 00:00:00pages
497-501issue
6eissn
0019-5189issn
0975-1009journal_volume
27pub_type
杂志文章abstract::Tadpoles of B. melanostictus and R. cyanophlyctis were reared in vitamin A solution. Rearing of the tadpoles of B. melanostictus in solutions containing 15, 20 and 30 IU/ml vitamin A palmitate resulted in complete disappearance of the keratinized epidermal material over the jaws and horny labial teeth. However tadpole...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:1994-07-01 00:00:00
abstract::A bioactive compound with antibacterial activity was isolated and purified from the extract of leaves of sunflower, Helianthus annuus. The bioactive compound was characterized using 1H and 13C NMR. The compound induced auxin, gibberellins and cytokinin in Oryza sativa and Phaseolus mungo. It also showed activity again...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:2008-12-01 00:00:00
abstract::Role of 5-HT3 receptors in cholinergic hypofunctional models of cognitive impairment in the elevated plus maze model and a passive avoidance model is studied. Cognitive impairment was caused by scopolamine (1 mg/kg, ip) in mice and 5-HT3 ligands mCPBG (1 and 5 mg/kg, ip) and ondansetron (0.5 and 5 mg/kg, ip) were admi...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:2002-02-01 00:00:00
abstract::Germ cell death and their removal from the seminiferous epithelium are common in the affected testis in conditions of unilateral ischemia or cryptorchidism; the similarities and differences, however, have not been studied between these two conditions. The present study was designed to examine the severity of the effec...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:2005-11-01 00:00:00
abstract::The present study has been undertaken to observe the effect of aqueous extract of M. oleifera (MO) leaf (300mg/kg body weight) on mean ulcer index, enterochromaffin (EC) cells and serotonin (5-hydroxytryptamine; 5-HT) content of ulcerated gastric tissue. Ulceration was induced by using aspirin (500 mg/kg, po), cerebel...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:2007-08-01 00:00:00
abstract::Dose matched comparison between copper complex of tolmetin(Tol-Cu) and tolmetin(Tol) was carried out in male albino rats bearing either sutured incision, dead space or excision wounds. Results showed that Tol significantly decreased tesile strength of incision and dead space wound. This effect was totally reversed by ...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:1995-03-01 00:00:00
abstract::The frequency and types of acrocentric chromosome association were quantitatively analysed in a Down syndrome child with unusual karyotype, 46, XX, -14, -22, t dic (14p;22p), +21, 21S+. Father and 4 sibs were heterozygous carriers for t dic (14p;22p). The variant 21S+ was inherited from the mother. The occurrence of t...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:1990-06-01 00:00:00
abstract::Bacopa monniera, Linn. (Brahmi: Scrophulariaceae) an Ayurvedic medicine is clinically used for memory enhancing, epilepsy, insomnia and as mild sedative. For the first time the effect of alcohol and hexane fraction of Brahmi has been studied on FeSO4 and cumene hydroperoxide induced lipid peroxidation. Alcohol fractio...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:1996-06-01 00:00:00
abstract::Fructose-fed rats were more susceptible to peroxidative damage as measured by thiobarbituric acid reactive species. The concentrations of lipid peroxides, diene conjugates, lipofuscin and hydroperoxides were significantly higher. The levels of enzymic antioxidants such as vitamin C, vitamin E and glutathione and activ...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:2002-09-01 00:00:00
abstract::Dual role of TGF-beta signaling in breast tumorigenesis as an inhibitor in early stages and promoter in advanced stages has been well established and known as TGF-beta switch. However, the biological mechanisms needs to be explored. Aim of the present study was to look for the usefulness of TGF-beta as a predictive ma...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:2011-11-01 00:00:00
abstract::During reproductive life in the female, there is a continuous flow of growth, maturation and demise of ovarian follicles, unless pregnancy occurs. Although ovarian function is primarily controlled by the hypothalamus-pituitary-axis, there is no doubt that a hormonal microenvironment specific for each individual follic...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章,评审
doi:
更新日期:2003-07-01 00:00:00
abstract::Prevalent notion about thyroid hormones is that thyroxine (T4) is a mere precursor and physiological effects of thyroid hormones are elicited by tri-iodothyronine (T3) after mono-deiodination of T4. Earlier studies on feather regeneration and molt done on spotted munia L. punctulata suggest that T4 (mono-deiodination ...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:2014-05-01 00:00:00
abstract::Molecular oxygen, a diradical, needs intervention of redox metal ions or other radicals to receive electrons for its reduction. The oxygen radicals thus produced are responsible for oxygen toxicity and oxidative stress. But, autoxidation, relevant in ischemia-reperfusion injury, is absent in any discussion on oxygen t...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:2016-11-01 00:00:00
abstract::Graded dose of amphetamine (AMP; 1-4 mg/kg, im) induced suppression of approach, contact, body jerk, grooming and food forage, hypervigilance (checking), stereotyped behaviour and oral hyperkinesia in rhesus monkeys. Pretreatment with haloperidol--a dopamine receptor blocking agent (0.04 mg/kg, im)--significantly supp...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:1995-12-01 00:00:00
abstract::Chronic administration of ethanol (2-5 g/kg, po) on days 1 to 6 and its withdrawal produced anxiogenic reaction in mice and rats as assessed on the elevated plus-maze. Daily administration of BR-16A (100 mg/kg) prior to ethanol intoxication for 6 days prevented withdrawal induced anxiety in both rats and mice. However...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:1993-05-01 00:00:00
abstract::Repeated weekly infections with S aureus, of bovine mammary origin, for three times evoked an immediate and a delayed type hypersensitivity in rabbits. The skin responses at 6 hr were characterized by oedema, haemorrhages and infiltration of polymorphonuclear cells. While at 24 hr it was dominated by mononuclear cells...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:1991-01-01 00:00:00
abstract::Effects of multiple weekly (20, 40 and 80 mg/kg) and daily therapeutic (2, 4 and 8 mg/kg) ip doses of C. colebrookianum leaf extract on liver and kidney functions and hematological parameters in mice were studied. No alteration in hematological and biochemical parameters at low and moderate dose level of daily and low...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:1994-03-01 00:00:00
abstract::Acute single dose administration of lanthanum chloride (250 mg/kg body wt, ip) to chicks have been found to alter the levels of enzymes of the antioxidant defence system of chick renal cortex fractions. Such changes involved significant decrease in activities of glucose-6-phosphate dehydrogenase, glutathione reductase...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:1992-12-01 00:00:00
abstract::Sulforaphane, a constituent of broccoli was investigated for its antimutagenic potential against different classes of cooked food mutagens (heterocyclic amines). These include imidazoazaarenes such as 2-amino-3-methylimidazo[4,5-f]quinoline (IQ), 2-amino-3,4-dimethylimidazo[4,5-f]quinoline (MeIQ), 2-amino-3,8-dimethyl...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:2003-03-01 00:00:00
abstract::Substance P (SP) injection in the plantar region of rat hind paw caused a dose related inflammation, which reached a peak within 10 min of injection and declined after 60 min. Low doses (0.25-0.063 mg/kg) of SP-antagonists like (D-Pro2, D-Trp7,9)-SP and (D-Pro2, D-Phe7, D-Trp9)-SP pretreatment significantly inhibited ...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:1990-10-01 00:00:00
abstract::Leaves of P. sativum the double mutant genotype tendril-less (tl) leaflet-development (lld), due to the action of lld mutation, produce many leaflets that are aborted at different stages of development. Morphological, vein pattern and histological observations showed that aborted leaflets became cup/bell/trumpet (cup)...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:2013-06-01 00:00:00
abstract::Changes in biomass yield rates, cell membrane stability (CMS), malondialdehyde (MDA) content and in the levels of physiological stress markers such as proline and glycine betaine in two high yielding genotypes (S1 and ATP, salt tolerant and salt sensitive, respectively) of mulberry under NaCl salinity were studied. Bi...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:2000-02-01 00:00:00
abstract::Mouse melanoma cells were treated with plumbagin, a naphthoquinone, from the plant Plumbago rosea at 0.5 microgram/ml (PI) for 60 min either alone or followed by 2 Gy gamma radiation (RT). Response to the different treatments was assessed by following the cell growth up to 5 days post treatment. PI alone produced a si...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:1996-09-01 00:00:00
abstract::Mouse liver was exposed in vivo to a continuous and unfocussed ultrasound of 875 KHz at 5, 10 or 15 W/cm2 for 300 sec spread over five days and excised on day 0, 1, 5 and 10 for studying the changes in Na+ and K+ reserves and Na-K-ATPase activity. At 5 and 10 W intensities the change in ionic concentrations and Na-K-A...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:1994-10-01 00:00:00
abstract::Biogenesis of various endogenous opioid peptides, anatomical distribution and the characteristics of multiple receptors with which they interact provides an opportunity for understanding the role of opioid systems and mechanism of opioid tolerance. Cellular and anatomical distribution of opioid receptor and their func...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章,评审
doi:
更新日期:2003-01-01 00:00:00
abstract::Two wheat varieties, T. durum (HD 4502) and T. aestivum (Kalyansona) were examined for photosynthesis rate and contents of sugars and rubisco protein in the flag leaf, at forenoon and afternoon at anthesis stage. A decrease in photosynthesis rate was observed in the afternoon compared to forenoon in both the varieties...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:2001-11-01 00:00:00
abstract::Azadirachta indica (AI, Neem) was tested for analgesic potency in experimental pain models in mice. In the glacial acetic acid (GAA) induced writhing test, AI (10, 30 and 100 mg/kg) dose-dependently reduced both the incidence and the number of writhes. Similarly, AI, at the dose levels tested, also enhanced tail withd...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:1995-11-01 00:00:00
abstract::Incidence of obesity and diabetes is increasing at an alarming rate not only among the populations of the affluent nations but also amongst the populations of the developing nations. Understanding the mechanisms that cause the onset of these pathological conditions is a requisite to effectively tackling this problem. ...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章,评审
doi:
更新日期:2000-09-01 00:00:00
abstract::Effects of adrenalectomy and administration of gonadotropins on cell counts of different cell types of spermatogenesis and morphology of the Leydig cells were studied in 30 day old mice. Adrenalectomy (duration, 12 days; age at autopsy 42 days) caused a significant decrease in the diameters of seminiferous tubules and...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:1999-02-01 00:00:00
abstract::Oral administration of 70% methanolic extract of T. cordifolia stem to male rats at the dose level of 100 mg/rat/day for 60 days did not cause body weight loss but decreased the weight of testes, epididymis, seminal vesicle and ventral prostate in a significant manner. Sperm motility as well as sperm density were redu...
journal_title:Indian journal of experimental biology
pub_type: 杂志文章
doi:
更新日期:2003-08-01 00:00:00