Abstract:
:Light microscopic study of hippocampal sub-regions demonstrated significant number of degenerated nerve cell bodies in the CA3, CA4 and dentate gyrus(Dg) areas of sodium fluoride administered adult female mice. Ultrastructural studies revealed neurodegenrative characteristics like involution of cell membranes, swelling of mitochondria, clumping of chromatin material etc, can be observed in cell bodies of CA3, CA4 and dentate gyrus (Dg). Fluoride intoxicated animals also performed poorly in motor co-ordination tests and maze tests. Inability to perform well increased with higher fluoride concentration in drinking water.
journal_name
Indian J Exp Bioljournal_title
Indian journal of experimental biologyauthors
Bhatnagar M,Rao P,Sushma J,Bhatnagar Rkeywords:
subject
Has Abstractpub_date
2002-05-01 00:00:00pages
546-54issue
5eissn
0019-5189issn
0975-1009journal_volume
40pub_type
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doi:
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