Abstract:
:We present the first X-ray study of a member of the arrestin family, the bovine retinal arrestin. Arrestin is essential for the fine regulation and termination of the light-induced enzyme cascade in vertebrate rod outer segments. It plays an important role in quenching phototransduction by its ability to preferentially bind to phosphorylated light-activated rhodopsin. The crystals diffract between 3 angstroms and 3.5 angstroms (space group P2(1)2(1)2, cell dimensions a = 169.17 angstroms, b = 185.53 angstroms, c = 90.93 angstroms, T = 100 K). The asymmetric unit contains four molecules with a solvent content of 68.5% by volume.
journal_name
FEBS Lettjournal_title
FEBS lettersauthors
Wilden U,Choe HW,Krafft B,Granzin Jdoi
10.1016/s0014-5793(97)01137-xsubject
Has Abstractpub_date
1997-10-06 00:00:00pages
268-70issue
3eissn
0014-5793issn
1873-3468pii
S0014-5793(97)01137-Xjournal_volume
415pub_type
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