Ricin-binding proteins along the endocytic pathway: the major endosomal ricin-binding protein is endosome-specific.

abstract：:δ-Catenin and β-catenin belong to different subfamilies of armadillo proteins but share some common binding partners, such as E-cadherin. This is the first study that demonstrated a novel common binding partner for δ-catenin and β-catenin, lymphoid enhancer factor-1 (LEF-1). We found that the N-terminus of δ-catenin (...

journal_title：Cell biology international

authors： He Y,Ki H,Kim H,Kim K

更新日期：2015-08-01 00:00:00

abstract：:A significant decrease in tissue pH or acidosis is a common feature of numerous diseases, including RA (rheumatoid arthritis). Cartilage homoeostasis is profoundly affected by local acidosis in the joints. The diuretic, amiloride, is neuroprotective in models of cerebral ischaemia, a property attributable to the inhib...

journal_title：Cell biology international

authors： Rong C,Chen FH,Jiang S,Hu W,Wu FR,Chen TY,Yuan FL

更新日期：2012-07-01 00:00:00

abstract：:Expression of four major reprogramming transgenes, including Oct4, Sox2, Klf4 and c-myc, in somatic cells enables them to have pluripotency. These cells are iPSC (induced pluripotent stem cell) that currently show the greatest potential for differentiation into cells of the three germ lineages. One of the issues facin...

journal_title：Cell biology international

authors： Shoae-Hassani A,Sharif S,Verdi J

更新日期：2011-10-01 00:00:00

abstract：:In the past decades increasing lines of evidence have demonstrated that adipose tissue, as an endocrine organ plays a central role in metabolic homeostasis and its related maladies. CCAAT/enhancer-binding protein (C/EBP) family members and the nuclear receptor peroxisome proliferator-activated receptor gamma (PPARγ) w...

journal_title：Cell biology international

authors： Zhao XY,Chen XY,Zhang ZJ,Kang Y,Liao WM,Yu WH,Xiang AP

更新日期：2015-04-01 00:00:00

abstract：:Observations made in live cells have clearly demonstrated that agonist-activated steroid/nuclear receptors reorganize in the nucleoplasm into hundreds of discrete speckled structures commonly referred to as nuclear foci. Subsequent studies have shown that nuclear foci are formed only with agonist- and not with pure an...

journal_title：Cell biology international

authors： Kumar S,Saradhi M,Chaturvedi NK,Tyagi RK

更新日期：2012-02-01 00:00:00

abstract：:DNA is constantly being damaged, either by endogenous or exogenous genotoxins. In that regard, DNA repair activities are essential for maintaining genomic stability and to life itself. Mutations in genes encoding DNA repair proteins cause severe human syndromes, but DNA repair defects have also been linked to several ...

journal_title：Cell biology international

authors： Prates Mori M,de Souza-Pinto NC

更新日期：2018-06-01 00:00:00

abstract：:Lysosomal permeability to potassium ions is an important property of the organelle. Influence of the membrane physical state on the potassium ion permeability of isolated lysosomes was assessed by measuring the membrane potential with bis(3-propyl-5-oxoisoxazol-4-yl)pentamethine oxonol and monitoring the lysosomal pro...

journal_title：Cell biology international

authors： Wang J,Zhang GJ

更新日期：2005-06-01 00:00:00

abstract：:Fgf8 is a member of the fibroblast growth factor (FGF) family that plays an important role in early neural development. Cellular aggregation and retinoic acid (RA) are needed for mouse embryonic carcinoma (EC) P19 cell neural differentiation. We have examined the Fgf8 gene in P19 cells during neural differentiation an...

journal_title：Cell biology international

authors： Alam AH,Suzuki H,Tsukahara T

更新日期：2009-09-01 00:00:00

abstract：:The present study aimed to investigate the potassium currents and further explore the role of potassium channels in drug response of gastric cancer cells. By patch-clamp technique, potassium currents of human gastric cancer cell SGC7901 were recorded in the mode of voltage clamp. Both 4-aminopyridine (4-AP) and tetrae...

journal_title：Cell biology international

authors： Han Y,Shi Y,Han Z,Sun L,Fan D

更新日期：2007-07-01 00:00:00

abstract：:Hematopoietic stem and progenitor cells (HSPCs) are attractive targets in regenerative medicine, although the differences in their homeostatic maintenance between sexes along time are still under debate. We accurately monitored hematopoietic stem cells (HSCs), common lymphoid progenitors (CLPs), and common myeloid pro...

journal_title：Cell biology international

authors： Gasco S,Rando A,Zaragoza P,García-Redondo A,Calvo AC,Osta R

更新日期：2017-12-01 00:00:00

abstract：:Lead is a heavy metal of considerable environmental and occupational concern and there is growing evidence that it is toxic to the human immune system. In this regard, this study examined the effect of lead (Pb) exposure to peritoneal macrophages (Mvarphis) of mice (Mus musculus) cultivated in DMEM medium supplemented...

journal_title：Cell biology international

authors： Gargioni R,Filipak Neto F,Buchi DF,Randi MA,Franco CR,Paludo KS,Pelletier E,Ferraro MV,Cestari MM,Bussolaro D,Oliveira Ribeiro CA

更新日期：2006-07-01 00:00:00

abstract：:Physical forces play a critical role in cell integrity and development, but little is known how cells convert mechanical signals into biochemical responses. This mini-review examines potential molecular mediators like integrins, focal adhesion proteins, and the cytoskeleton in the context of a complex cell structure. ...

journal_title：Cell biology international

authors： Goldmann WH

更新日期：2002-01-01 00:00:00

abstract：:MSCs (mesenchymal stem cells) are planned foruse in regenerative medicine to offset age-dependent alterations. However, MSCs are affected by replicative senescence associated with decreasing proliferation potential, telomere shortening and DNA damage during in vitro propagation. To monitor in vitro senescence, we have...

journal_title：Cell biology international

authors： Fuchs R,Stelzer I,Drees CM,Rehnolt C,Schraml E,Sadjak A,Schwinger W

更新日期：2012-01-01 00:00:00

abstract：:This review outlines the basic properties of T-tubules in skeletal muscle cells, and the factors that govern reversible vacuolation in T-tubules under experimental conditions. Comparable membranous transformations, involving the plasma membrane or occurring intracellularly, in non-muscle cells are then considered. Fin...

journal_title：Cell biology international

authors： Krolenko SA,Lucy JA

更新日期：2002-01-01 00:00:00

abstract：:Large numbers of autogenous melanocytes (Mcs) are required when conducting studies on tissue engineering of skin and performing surgical treatment of depigmentation diseases. This study was conducted to explore the possibility of inducing differentiation of bone marrow mesenchymal stem cells (MSCs) into Mcs as a means...

journal_title：Cell biology international

authors： Mei X,Sun Y,Wu Z,Pan W,Zhu J,Shi W

更新日期：2015-07-01 00:00:00

abstract：:Mitotic spindles of the diatom Pinnularia viritiformis stained with the fluorescent actin-labelling reagent bodipyphallacidin revealed actin among the chromosomes and extending along the spindle to the poles. This is the first report of actin's presence within spindles of this ecologically important group of organisms...

journal_title：Cell biology international

authors： Sampson K

更新日期：2004-01-01 00:00:00

abstract：:Zebularine is a cytidine analogue incorporated into DNA during replication, inhibiting DNA methyltransferase 1 (DNMT1), resulting in demethylation and changes in gene expression. Such modification may improve radiosensitivity in resistant lymphoma cells. The hypothesis of this study was that zebularine and radiation w...

journal_title：Cell biology international

authors： Bryan JN,Kumar SR,Jia F,Balkin ER,Lewis MR

更新日期：2014-02-01 00:00:00

abstract：:The size and number of secretory granules in late larval salivary glands of Drosophila melanogaster have been related to interecdysial and early metamorphic development represented by well-known puffs in polytene chromosomes. Interecdysial period (puff stage 1 (PS1)) is characterized by presence of numerous small gran...

journal_title：Cell biology international

authors： Farkas R,Suáková G

更新日期：1999-01-01 00:00:00

abstract：:Chloride secretion in primary cultures of cells originating from the secretory coil of human sweat glands was investigated by electron probe X-ray microanalysis. The total intracellular Cl concentration was lowered by muscarinic agonists (carbachol and acetylcholine), as well as by the calcium ionophore A23187. The mu...

journal_title：Cell biology international

authors： Mörk AC,Hongpaisan J,Roomans GM

更新日期：1995-02-01 00:00:00

abstract：:Neuroblastoma is the most common tumor diagnosed in children and infants, with high recurrence and poor prognosis. Angelica sinensis polysaccharide (AP) whose average molecular weight is 72,900 Da possesses various bioactivities. We aimed to explore the effects of AP on neuroblastoma SH-SY5Y cells as well as the under...

journal_title：Cell biology international

authors： Yang J,Shao X,Jiang J,Sun Y,Wang L,Sun L

更新日期：2018-07-01 00:00:00

abstract：:Stem cell therapy in recent years has gained much attention as the modern therapeutic approach to treat diseases. Mesenchymal stem cells (MSCs) are seen as the most reliable cells applied in therapy over other stem cells because of their versatility. Bone and cartilage diseases (osteo-diseases) are the major target of...

journal_title：Cell biology international

authors： Ghasroldasht MM,Irfan-Maqsood M,Matin MM,Bidkhori HR,Naderi-Meshkin H,Moradi A,Bahrami AR

更新日期：2014-10-01 00:00:00

abstract：:Cell motility, cell migration and phagocytosis are distinct, though frequently sequential, processes. They are fundamental for the maintenance of homoeostasis in single cells as well as in pluricellular organisms. Like vertebrates, invertebrate immune functions are strictly dependent on cell motility, chemotaxis and p...

journal_title：Cell biology international

authors： Malagoli D,Ottaviani E

更新日期：2010-11-01 00:00:00

abstract：:Resistance to radiotherapy and chemotherapy has been a major problem of conventional cancer therapies, which consequently leads to cancer relapse and cancer-related death. It is known that cancer stem cells (CSCs) play a key role in therapy resistance and CSC-based targeted therapies have been considered as a powerful...

journal_title：Cell biology international

authors： Johari B,Rahmati M,Nasehi L,Mortazavi Y,Faghfoori MH,Rezaeejam H

更新日期：2020-12-01 00:00:00

abstract：:Investigation of the relative slowness with which trypsin detaches epithelial cells from their adhesions with a substratum suggests that the adherent surface of the cells is normally rather inaccessible to the enzyme. Trypsinisation of cells through a porous filter allowing access of the enzyme to the underside of the...

journal_title：Cell biology international

authors： Simpson K,McGrath M,Curtis A

更新日期：1993-03-01 00:00:00

abstract：:Neural stem cells (NSCs) are currently considered powerful candidates for cell therapy in neurodegenerative disorders such as Parkinson's disease. However, it is not known when and how NSCs begin to differentiate functionally. Recent reports suggest that classical neurotransmitters such as acetylcholine (Ach) are invo...

journal_title：Cell biology international

authors： Zhou C,Wen ZX,Shi DM,Xie ZP

更新日期：2004-01-01 00:00:00

abstract：:Cell behaviour in 3D environments can be significantly different from those in 2D cultures. With many different 3D matrices being developed and many experimental modalities used to modulate cell behaviour in 3D, it is necessary to develop high throughput techniques to study behaviour in 3D. We report on a 3D array on ...

journal_title：Cell biology international

authors： Zhao S,Gao R,Devreotes PN,Mogilner A,Zhao M

更新日期：2013-09-01 00:00:00

abstract：:Oral squamous cell carcinoma (OSCC) is a common cancer with poor prognosis and high mortality. The role of CCN5 has attracted a great focus on the regulation of cancer progression. However, the biological function and mechanism of CCN5 in OSCC are still not well elucidated. The current study was designed to determine ...

journal_title：Cell biology international

authors： Sun S,Cui Z,Yan T,Wu J,Liu Z

更新日期：2020-04-01 00:00:00

abstract：:Retinoic acid (RA) and oleanolic acid (OA) were studied about their potential to induce mouse embryonic stem cell R1/E (MESC-R1/E) to differentiate toward germ cells. Embryoid bodies (EBs) first formed from MESC-R1/E and EBs were allowed to attach to the bottoms of normal cell-culturing plate and grow. Then, different...

journal_title：Cell biology international

authors： Wan Q,Lu H,Wu LT,Liu X,Xiang JB

更新日期：2014-12-01 00:00:00

abstract：:The objective of this study was to examine the changes in the activity and expression of ectonucleotidase enzymes in the model of unilateral cortical stab injury (CSI) in rat. The activities of ecto-nucleoside triphosphate diphosphohydrolase 1 (NTPDase 1) and ecto 5'-nucleotidase were assessed by measuring the levels ...

journal_title：Cell biology international

authors： Nedeljkovic N,Bjelobaba I,Subasic S,Lavrnja I,Pekovic S,Stojkov D,Vjestica A,Rakic L,Stojiljkovic M

更新日期：2006-06-01 00:00:00

abstract：:This review summarizes the results of our investigations of actin unfolding-refolding and presents the notion that protein unfolding pathway, the number and the appearance order of intermediate states do not dependent on denaturing agents. To place our concept in the context of current knowledge of protein folding, we...

journal_title：Cell biology international

authors： Povarova OI,Kuznetsova IM,Turoverov KK

更新日期：2007-04-01 00:00:00