Abstract:
:The size and number of secretory granules in late larval salivary glands of Drosophila melanogaster have been related to interecdysial and early metamorphic development represented by well-known puffs in polytene chromosomes. Interecdysial period (puff stage 1 (PS1)) is characterized by presence of numerous small granules (11,000 per cell). The transition from PSI to early metamorphic phase (PS2 and upwards), induced by rapid elevation in endogenous steroid hormone ecdysone, is accompanied by continuous growth of granule diameter with concomitant reduction in their number per cell. In the PS4, just prior to secretion, approximately 3000 mature granules occur per cell. The mature state is associated with the change from hyperbolic to Gaussian distribution of granule number over their size range. Similar changes in secretory granule parameters were observed in interecdysial salivary glands explanted from 3rd instar larvae and cultured in vitro in medium containing 5x10(-6) m ecdysone.
journal_name
Cell Biol Intjournal_title
Cell biology internationalauthors
Farkas R,Suáková Gdoi
10.1006/cbir.1999.0433keywords:
subject
Has Abstractpub_date
1999-01-01 00:00:00pages
671-6issue
10eissn
1065-6995issn
1095-8355pii
S1065-6995(99)90433-Xjournal_volume
23pub_type
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