Intracellular signal transduction pathways induced by leptin in C2C12 cells.

abstract：:Osteocalcin is one of the most abundant non-collagenous proteins in bone that is commonly used as a preliminary biomarker in bone formation. Osteocalcin also regulates energy metabolism as a hormone. Estrogen-related receptor alpha (ERRα) is primarily thought to regulate energy homeostasis through interacting with per...

journal_title：Cell biology international

authors： Wang H,Wang J

更新日期：2013-11-01 00:00:00

abstract：:X-box-binding protein 1 (XBP-1) is a basic-region leucine zipper protein in the cyclic AMP response element binding protein/activating transcription factor (CREB/ATF) family of transcription factors involved in different cell-differentiation processes. We have investigated the expression of XBP-1 in differentiating MC...

journal_title：Cell biology international

authors： Zambelli A,Mongiardini E,Villegas SN,Carri NG,Boot-Handford RP,Wallis GA

更新日期：2005-08-01 00:00:00

abstract：:Oxidative stress can be defined as the increase of oxidizing agents like reactive oxygen and nitrogen species, or the imbalance between the antioxidative defense mechanism and oxidants. Cell cycle checkpoint response can be defined as the arrest of the cell cycle functioning after damaging chemical exposure. This temp...

journal_title：Cell biology international

authors： Akcakaya H,Dal F,Tok S,Cinar SA,Nurten R

更新日期：2015-02-01 00:00:00

abstract：:At the early stage of atherosclerosis, neointima is formed due to the migration of vascular smooth muscle cells (VSMCs) from the media to the intima. VSMCs are surrounded by highly adhesive 3D matrices. They take specific strategies to cross various 3D matrices in the media, including heterogeneous collagen and mechan...

journal_title：Cell biology international

authors： Chi Q,Shan J,Ding X,Yin T,Wang Y,Jia D,Wang G

更新日期：2017-06-01 00:00:00

abstract：:Cell proliferation rates of diagnostic marrow aspirate cells of 21 children with Acute Lymphoblastic Leukaemia and 16 controls were compared using immunocytochemical labelling of PCNA and Ki-67 antigen as assessed by Confocal Laser Scanning Microscopy. The results showed an unexpected, highly significant degree of dis...

journal_title：Cell biology international

authors： Ball LM,Pope J,Howard CV,Eccles P,van Velzen D

更新日期：1994-09-01 00:00:00

abstract：:We have monitored the effects of KLKL(5)KLK (KLK), a derivative of a natural cationic antimicrobial peptide (CAP) on isolated membrane vesicles, and investigated the partition of the peptide within these structures. KLK readily interacted with fluorescent dyes entrapped in the vesicles without apparent pore formation....

journal_title：Cell biology international

authors： Aichinger MC,Ortbauer M,Reipert S,Zauner W,Bogner P,Froschauer E,Nowikovsky K,Lingnau K,von Gabain A,Schweyen R,Henics T

更新日期：2008-11-01 00:00:00

abstract：:The vasoactive hydrophilic amine histamine is the most important molecule released by mast cells. However, histamine's role in activating intracellular responses in HGFs (human gingival fibroblasts) has not been evaluated to date. In the present study, we investigated the effect of histamine and of Gram-negative [LPS ...

journal_title：Cell biology international

authors： Gutiérrez-Venegas G,Cruz-Arrieta S,Villeda-Navarro M,Méndez-Mejía JA

更新日期：2011-10-01 00:00:00

abstract：:Fgf8 is a member of the fibroblast growth factor (FGF) family that plays an important role in early neural development. Cellular aggregation and retinoic acid (RA) are needed for mouse embryonic carcinoma (EC) P19 cell neural differentiation. We have examined the Fgf8 gene in P19 cells during neural differentiation an...

journal_title：Cell biology international

authors： Alam AH,Suzuki H,Tsukahara T

更新日期：2009-09-01 00:00:00

abstract：:Prolapsus uteri in pelvic supportive disorders are common in elderly women, and their etiology remains unclear. We examined elastin-binding proteins (EBPs) and binding sites in cultured cardinal ligament fibroblasts derived from elderly patients with prolapsus uteri (HPLiF) and compared them with those from age-matche...

journal_title：Cell biology international

authors： Yamamoto M,Akazawa K,Aoyagi M,Yamamoto N,Yamamoto K

更新日期：2002-01-01 00:00:00

abstract：:Trophoblast cells play a vital role in embryo implantation. Exploring cytokines secreted by trophoblast cells will be significant in revealing the molecular mechanism of embryo implantation. In vitro-cultured trophoblast cells treated with Lefty revealed that Lefty could downregulate the expression of Nodal while prom...

journal_title：Cell biology international

authors： Li H,Cao R,Bai L,Qiao XM,Zhao YQ

更新日期：2018-09-01 00:00:00

abstract：:Menstrual blood is easily accessible, renewable, and inexpensive source of stem cells that have been interested for cell therapy of neurodegenerative diseases. In this study, we showed conversion of menstrual blood stem cells (MenSCs) into clonogenic neurosphere- like cells (NSCs), which can be differentiated into gli...

journal_title：Cell biology international

authors： Azedi F,Kazemnejad S,Zarnani AH,Behzadi G,Vasei M,Khanmohammadi M,Khanjani S,Edalatkhah H,Lakpour N

更新日期：2014-05-01 00:00:00

abstract：:Nuclear co-repressor (NCoR) regulates peripheral insulin sensitivity; however, its role in modulating insulin sensitivity in skeletal muscle remains elusive. Present study investigated protein expression and effect of NCoR on insulin sensitivity in murine skeletal muscle cell line C2 C12 . Myotubes as compared to myob...

journal_title：Cell biology international

authors： Choudhary AK,Dey CS

更新日期：2017-02-01 00:00:00

abstract：:Induction of HO-1 protein can have both beneficial and detrimental effects for cells, including regulating proliferation and apoptosis of several tumours. We have investigated the regulation of HO-1, p38MAPK and mTOR in the context of proliferation, cell cycle events and apoptosis of oesophageal squamous cell carcinom...

journal_title：Cell biology international

authors： Hu JL,Xiao L,Li ZY,Wang Q,Chang Y,Jin Y

更新日期：2013-06-01 00:00:00

abstract：:The influence of daunorubicin (DNR) on survival of human normal (S-126) and trisomic, with respect to chromosome 21 (T-164; S-240), skin fibroblasts and some parameters related to it, such as intracellular drug accumulation, distribution and interaction with cell membrane, were studied. The in vitro growth-inhibition ...

journal_title：Cell biology international

authors： Przybylska M,Koceva-Chyla A,Rózga B,Józwiak Z

更新日期：2001-01-01 00:00:00

abstract：:We studied the genotoxic potential of a carcinogen in the human hepatoma cell line, HepG2, and in primary rat hepatocyte culture. HepG2 is a well differentiated human hepatoblastoma cell line with biotransforming capacity. Rat hepatocytes were obtained by the standard two-step in situ perfusion technique. Following be...

journal_title：Cell biology international

authors： Liu TY,Chao TW,Chiang SH,Chi CW

更新日期：1993-04-01 00:00:00

abstract：:The presence of myosin and dynein in the ovaries of both Apis mellifera and Scaptotrigona postica was investigated in extracts and in histological sections. In the ovary extracts, motor proteins, myosins V, VI and dynein were detected by Western blot. In histological sections, they were detected by immunocytochemistry...

journal_title：Cell biology international

authors： Patricio K,Calábria LK,Peixoto PM,Espindola FS,Da Cruz-Landim C

更新日期：2010-10-01 00:00:00

abstract：:It has been reported that chronic inflammation of the vessel wall is a hallmark of atherosclerosis. Interleukin-6 (IL-6) is regarded as an important modulator of inflammatory events occurring during all stages of atherogenesis. Although many factors that induce IL-6 expression have been identified, the effect of homoc...

journal_title：Cell biology international

authors： Zhang L,Jin M,Hu XS,Zhu JH

更新日期：2006-07-01 00:00:00

abstract：:Tripartite motif protein 25 (TRIM25) expression was altered in various human cancers. Herein, we found that the expression of TRIM25 was elevated in hepatocellular carcinoma (HCC) tissues and cell lines. Knockdown of TRIM25 increased the sensitivity of HCC HepG2 cells to epirubicin (EPI), as indicated by reduced cell ...

journal_title：Cell biology international

authors： Yuan P,Zheng A,Tang Q

更新日期：2020-07-01 00:00:00

abstract：:MSCs (mesenchymal stem cells) are planned foruse in regenerative medicine to offset age-dependent alterations. However, MSCs are affected by replicative senescence associated with decreasing proliferation potential, telomere shortening and DNA damage during in vitro propagation. To monitor in vitro senescence, we have...

journal_title：Cell biology international

authors： Fuchs R,Stelzer I,Drees CM,Rehnolt C,Schraml E,Sadjak A,Schwinger W

更新日期：2012-01-01 00:00:00

abstract：:An effect of magnesium on calcium-induced depolarisation of mitochondrial transmembrane potential (DeltaPsi(m)) was investigated. Depending on the presence of Mg(2+), addition of Ca(2+) to suspension of isolated rat heart mitochondria induced either reversible depolarisation or irreversible collapse of succinate-drive...

journal_title：Cell biology international

authors： Racay P

更新日期：2008-01-01 00:00:00

abstract：:Neuroblastoma is one of the most common solid tumours in children (8-10% of all malignancies). Over 22% of cases have N-myc amplification associated with aggressively growing neuroblastomas. Oncogene-induced sensitization of cells to apoptosis is an important mechanism for suppression of tumorigenesis. Tumour suppress...

journal_title：Cell biology international

authors： Li T,Wang L,Ke XX,Gong XY,Wan JH,Hao XW,Xu M,Xiang Z,Cui ZB,Cui H

更新日期：2012-04-01 00:00:00

abstract：:The formation of vertebrate skeletal muscles widely thought to be under the control of hierarchy of regulatory genes. MYF5 is one of the myogenic determination gene expressed in the developing mouse dermomyotome which control skeletal muscle differentiation. In the current work, we had obtained the cDNA sequence inclu...

journal_title：Cell biology international

authors： Nie YW,Ding XB,Ge XG,Fan HL,Liu ZW,Guo H

更新日期：2013-09-01 00:00:00

abstract：:Neuroinflammation is closely related with the pathogenesis and progress of neurodegenerative diseases including Alzheimer's disease (AD). Loganin, an iridoid glycoside obtained from traditional Chinese medicine Cornus officinalis, has properties of inhibiting inflammation and improving memory. The present study was ai...

journal_title：Cell biology international

authors： Cui Y,Wang Y,Zhao D,Feng X,Zhang L,Liu C

更新日期：2018-12-01 00:00:00

abstract：:DCs (dendritic cells) are the strongest professional APCs (antigen-presenting cells) to initiate immune responses against pathogens, but they are usually incompetent in initiating efficient immune responses in the progress of solid tumours. We have shown that Notch signalling plays a pivotal role in DC-dependent anti-...

journal_title：Cell biology international

authors： Feng F,Yang J,Tong L,Yuan S,Tian Y,Hong L,Wang W,Zhang H

更新日期：2012-03-01 00:00:00

abstract：:Increasing potassium chloride concentration from 0 to 100 mM and magnesium chloride from 0 to 2 mM show a parallel rate increase in polymerizing actin, whereas increasing calcium chloride concentration from 0 to 0.2 mM decreases the rate of polymerizing actin. The presence of alpha-actinin has little influence on the ...

journal_title：Cell biology international

authors： Goldmann WH

更新日期：2002-01-01 00:00:00

abstract：:Many disturbances in electrolyte and hormonal balance in the body induced by functional impairment of renal parenchyma may affect the activity of amine precursor uptake and decarboxylation (APUD) cells, which constitute a very important link in the regulation of homeostasis. The aim of the present study was the morpho...

journal_title：Cell biology international

authors： Kasacka I

更新日期：2004-01-01 00:00:00

abstract：:The effect of piperine on the fertilization of eggs with sperm was investigated in female hamsters. They were intragastrically treated with piperine at doses of 50 and 100 mg/kg BW from day 1 through day 4 of the oestrous cycle. During piperine treatment, these females were superovulated and artificially inseminated (...

journal_title：Cell biology international

authors： Piyachaturawat P,Pholpramool C

更新日期：1997-07-01 00:00:00

abstract：:To better treat patients with non-small cell lung cancer (NSCLC), the investigations on novel molecules affecting NSCLC progression are of vital importance. Long noncoding RNAs (lncRNAs) are identified as pivotal regulators that can affect the cellular activities of carcinomas. Long intergenic non-protein coding RNA 6...

journal_title：Cell biology international

authors： Yang H,Yang W,Dai W,Ma Y,Zhang G

更新日期：2020-08-01 00:00:00

abstract：:Earlier, we have shown that spontaneously isolated non-pathogenic bacteria Serratia grimesii and Serratia proteamaculans invade eukaryotic cells, provided that they synthesize thermolysin-like metalloproteases ECP32/grimelysin or protealysin characterized by high specificity towards actin. To address the question of w...

journal_title：Cell biology international

authors： Bozhokina ES,Tsaplina OA,Efremova TN,Kever LV,Demidyuk IV,Kostrov SV,Adam T,Komissarchik YY,Khaitlina SY

更新日期：2011-02-01 00:00:00

abstract：:The diabetic milieu is believed to change the activity, or result in damage of podocytes-a key component of the glomerular filtration barrier and known to secrete matrix for glomerular basement membrane. This in turn contributes to diabetic nephropathy. However, how podocyte dysfunction is triggered in diabetic nephro...

journal_title：Cell biology international

authors： Liu Y,Long L,Yuan F,Liu F,Liu H,Peng Y,Sun L,Chen G

更新日期：2015-02-01 00:00:00