当前位置： SCI文献检索 > CELL BIOLOGY INTERNATIONAL期刊下所有文献 > Differentiation potential of menstrual blood- versus bone marrow-stem cells into glial-like cells.

Differentiation potential of menstrual blood- versus bone marrow-stem cells into glial-like cells.

Abstract：

:Menstrual blood is easily accessible, renewable, and inexpensive source of stem cells that have been interested for cell therapy of neurodegenerative diseases. In this study, we showed conversion of menstrual blood stem cells (MenSCs) into clonogenic neurosphere- like cells (NSCs), which can be differentiated into glial-like cells. Moreover, differentiation potential of MenSCs into glial lineage was compared with bone marrow stem cells (BMSCs). Differentiation potential of individual converted NSCs derived from MenSCs or BMSCs into glial-like cells was investigated using immunofluorescence staining and real-time polymerase chain reaction.The fibroblastic morphology of both MenSCs and BMSCs was turned into NSCs shape during first step of differentiation. NSCs derived from both BMSCs and MenSCs expressed higher levels of Olig-2 and Nestin markers compared to undifferentiated cells. The expression levels of myelin basic protein (MBP) mRNA up regulated only in BMSCs-NSCs no in MenSCs-NSCs. However, outgrowth of individual NSCs derived from both MenSCs and BMSCs into glial-like cells led to significant up regulation of glial fibrillary acidic protein,Olig-2 and MBP at mRNA and protein level accompanied with down regulation of Nestin protein.This is the first study demonstrating that MenSCs can be converted to NSCs with differentiation ability into glial-like cells. Accumulative data show different expression pattern of glial markers in differentiated MenSCs compared to BMSCs. The comparable differentiation potential, more accessibility and no invasive technique for sample collection of MenSCs in comparison with BMSCs introduce MenSCs as an apt, consistent and safe alternative to BMSCs for cell therapy of neurodegenerative diseases.

journal_name

Cell Biol Int

journal_title

Cell biology international

authors

Azedi F,Kazemnejad S,Zarnani AH,Behzadi G,Vasei M,Khanmohammadi M,Khanjani S,Edalatkhah H,Lakpour N

doi

10.1002/cbin.10245

subject

Has Abstract

pub_date

2014-05-01 00:00:00

pages

615-24

issue

5

eissn

1065-6995

issn

1095-8355

journal_volume

38

pub_type

杂志文章

相关文献

CELL BIOLOGY INTERNATIONAL文献大全
  • Inhibition of zoledronic acid derivatives with extended methylene linkers on osteoclastogenesis involve downregulation of JNK and Akt pathways.

    abstract：:Bisphosphonates (BPs), especially zoledronic acid (ZOL), are clinically used to treat osteolytic bone lesions. However, serious side-effects may be also induced during the therapeutic process. To improve the BPs drugs, here, we investigated the effects of a series of ZOL derivatives with increasing number of methylene...

    journal_title：Cell biology international

    pub_type： 杂志文章

    doi：10.1002/cbin.11546

    authors： Peng Y,Liu Q,Xu D,Li K,Li H,Qiu L,Lin J

    更新日期：2021-01-06 00:00:00

  • The effect of oxidative stress induced by t-butyl hydroperoxide on the structural dynamics of membrane proteins of Chinese hamster fibroblasts.

    abstract：:A method based on the measurement at room temperature of tryptophan phosphorescence (RTTP) gives the unique possibility to investigate the dynamic structure of membrane proteins without their isolation from cells. This method was used to study the influence of tert- butyl hydroperoxide (t -BHP) on Chinese hamster fibr...

    journal_title：Cell biology international

    pub_type： 杂志文章

    doi：10.1006/cbir.1999.0366

    authors： Mazhul V,Shcherbin D,Zavodnik I,Rekawiecka K,Bryszewska M

    更新日期：1999-01-01 00:00:00

  • Genetic networks in nonpermissive temperature-induced cell differentiation of Sertoli TTE3 cells harboring temperature-sensitive SV40 large T-antigen.

    abstract：:To identify the molecular basis by which nonpermissive temperature (NPT) induces cell differentiation in Sertoli TTE3 cells harboring temperature-sensitive SV40 large T-antigen, we performed global scale microarray and computational gene network analyses. In TTE3 cells, inactivation of the large T-antigen by a NPT at ...

    journal_title：Cell biology international

    pub_type： 杂志文章

    doi：10.1016/j.cellbi.2007.04.007

    authors： Tabuchi Y,Takasaki I,Suto A,Kondo T,Suzuki Y,Obinata M

    更新日期：2007-10-01 00:00:00

  • Prostate cancer cells modulate the differentiation of THP-1 cells in response to etoposide and TLR agonists treatments.

    abstract：:The aim of this study was to determine the polarization of macrophages in the tumor microenvironment, as well as the effect of soluble factors secreted from these polarized macrophages on etoposide-induced cancer cell apoptosis. We investigated the effect of soluble factors secreted from the supernatant of PC3 cells t...

    journal_title：Cell biology international

    pub_type： 杂志文章

    doi：10.1002/cbin.11410

    authors： Malekghasemi S,Majidi J,Baradaran B,Aghebati-Maleki L

    更新日期：2020-10-01 00:00:00

  • Immunological identification of types I and III collagen in bovine lens epithelium and its anterior lens capsule.

    abstract：:To define the molecular structure of bovine lens epithelium and its anterior lens capsule, we investigated the composition of lens capsule basement membrane proteins. Immunofluorescence and immunogold techniques were used to demonstrate the presence of type I and type III collagen in the lens capsule and in primary ex...

    journal_title：Cell biology international

    pub_type： 杂志文章

    doi：10.1016/j.cellbi.2004.09.012

    authors： Sawhney RS

    更新日期：2005-02-01 00:00:00

  • VEGF expression is regulated by HIF-1α and ARNT in 3D KYSE-70, esophageal cancer cell spheroids.

    abstract：:In 3D cultured cell systems, the cells form 3D spheroids that mimic cancer cell spheroids in vivo. Cancer cells form cell spheroids as they grow. The in vivo spheroids do not contain a vascular network; therefore, oxygen and nutrition supplies are insufficient. Specifically, the cells in the core region of the cluster...

    journal_title：Cell biology international

    pub_type： 杂志文章

    doi：10.1002/cbin.10656

    authors： Terashima J,Sampei S,Iidzuka M,Ohsakama A,Tachikawa C,Satoh J,Kudo K,Habano W,Ozawa S

    更新日期：2016-11-01 00:00:00

  • Homocysteine stimulates nuclear factor kappaB activity and interleukin-6 expression in rat vascular smooth muscle cells.

    abstract：:It has been reported that chronic inflammation of the vessel wall is a hallmark of atherosclerosis. Interleukin-6 (IL-6) is regarded as an important modulator of inflammatory events occurring during all stages of atherogenesis. Although many factors that induce IL-6 expression have been identified, the effect of homoc...

    journal_title：Cell biology international

    pub_type： 杂志文章

    doi：10.1016/j.cellbi.2006.03.007

    authors： Zhang L,Jin M,Hu XS,Zhu JH

    更新日期：2006-07-01 00:00:00

  • Spaghetti, a homolog of human RPAP3 (RNA polymerase II-associated protein 3), determines the fate of germline stem cells in Drosophila ovary.

    abstract：:The Drosophila ovary provides an attractive model for studying the extrinsic or intrinsic factors that regulate the fate of germline stem cells (GSCs). Using this model, we identified a new role for Drosophila spaghetti (spag), encoding a homolog of human RNA polymerase II-associated protein 3 (RPAP3), in regulating t...

    journal_title：Cell biology international

    pub_type： 杂志文章

    doi：10.1002/cbin.10900

    authors： Chen D,Tao X,Zhou L,Sun F,Sun M,Fang X

    更新日期：2018-07-01 00:00:00

  • Ion transport in primary cultures from human sweat gland coils studied with X-ray microanalysis.

    abstract：:Chloride secretion in primary cultures of cells originating from the secretory coil of human sweat glands was investigated by electron probe X-ray microanalysis. The total intracellular Cl concentration was lowered by muscarinic agonists (carbachol and acetylcholine), as well as by the calcium ionophore A23187. The mu...

    journal_title：Cell biology international

    pub_type： 杂志文章

    doi：10.1006/cbir.1995.1056

    authors： Mörk AC,Hongpaisan J,Roomans GM

    更新日期：1995-02-01 00:00:00

  • New indices in morphometry of nuclear structure in the NIH 3T3 cell line.

    abstract：:We analyzed the connection of changes in nucleus ploidy with changes in nucleolar apparatus of NIH 3T3 cells. The quantity of nucleoli does not depend on the quantity of nucleolar DNA, but instead depends on euploidy: the majority of euploid cells have 1-3 nucleoli. The quantity of DNA in the nucleolus is correlated w...

    journal_title：Cell biology international

    pub_type： 杂志文章

    doi：10.1016/s1065-6995(03)00158-6

    authors： Karalyan ZA,Djaghatspanyan NG,Gasparyan MH,Hakobyan LA,Abroyan LO,Magakyan YH,Ter-Pogossyan ZR,Kamalyan LA,Avagyan VY,Karalova EM

    更新日期：2003-01-01 00:00:00

  • Cytostatic effect of inostamycin, an inhibitor of cytidine 5'-diphosphate 1,2-diacyl-sn-glycerol (CDP-DG): inositol transferase, on oral squamous cell carcinoma cell lines.

    abstract：:Inostamycin, which was recently isolated from Streptomyces sp. MH816-AF15 as an inhibitor of cytidine 5'-diphosphate 1,2-diacyl-sn-glycerol (CDP-DG): inositol transferase, caused a G1-phase accumulation in the cell cycle of small cell lung carcinomas. To investigate whether the cytostatic effect of inostamycin is rest...

    journal_title：Cell biology international

    pub_type： 杂志文章

    doi：10.1006/cbir.2000.0706

    authors： Baba Y,Tsukuda M,Mochimatsu I,Furukawa S,Kagata H,Nagashima Y,Koshika S,Imoto M,Kato Y

    更新日期：2001-01-01 00:00:00

  • Interleukin-6-induced production of type II acute phase proteins and expression of junB gene are downregulated by human recombinant growth hormone in vitro.

    abstract：:Growth hormone (GH), given therapeutically in many human diseases, is able to modulate the maturation and function of many cells of immune system. The present study demonstrates the effect of human recombinant GH on the production of acute phase proteins (APP) as well as on the gene expression of junB proto-oncogene o...

    journal_title：Cell biology international

    pub_type： 杂志文章

    doi：10.1006/cbir.1999.0454

    authors： Derfalvi B,Igaz P,Fulop KA,Szalai C,Falus A

    更新日期：2000-01-01 00:00:00

  • Staurosporine-induced morphological changes in the rat osteoblasts.

    abstract：:Treatment of cultured rat osteoblasts with staurosporine caused a rapid outgrowth of long slender cellular processes and the formation of stellate cells. The number of stellate cells increased with higher concentrations of and longer incubation with staurosporine. Scanning electron microscopy (SEM) revealed that the s...

    journal_title：Cell biology international

    pub_type： 杂志文章

    doi：10.1006/cbir.1993.1007

    authors： Yang RS,Lu KS,Fu WM,Liu TK,Lin-Shiau SY

    更新日期：1993-01-01 00:00:00

  • Inhibition of Ca2+/calmodulin-dependent protein kinase or epidermal growth factor receptor tyrosine kinase abolishes lysophosphatidic acid-mediated DNA-synthesis in human myometrial smooth muscle cells.

    abstract：:Human myometrial smooth muscle cells (SMCs) were used to evaluate the proliferative activity of lysophosphatidic acid (LPA). This study specifically focuses on the role of Ca(2+)/calmodulin-dependent protein (CaM) kinase and epidermal growth factor (EGF) receptor tyrosine kinase. Myometrial SMCs were cultured from bio...

    journal_title：Cell biology international

    pub_type： 杂志文章

    doi：10.1016/s1065-6995(02)00352-9

    authors： Nilsson UK,Svensson SP

    更新日期：2003-01-01 00:00:00

  • OP9-DL1 cell co-culture enhances anti-tumour immunity of mouse bone marrow-derived dendritic cells.

    abstract：:DCs (dendritic cells) are the strongest professional APCs (antigen-presenting cells) to initiate immune responses against pathogens, but they are usually incompetent in initiating efficient immune responses in the progress of solid tumours. We have shown that Notch signalling plays a pivotal role in DC-dependent anti-...

    journal_title：Cell biology international

    pub_type： 杂志文章

    doi：10.1042/CBI20100462

    authors： Feng F,Yang J,Tong L,Yuan S,Tian Y,Hong L,Wang W,Zhang H

    更新日期：2012-03-01 00:00:00

  • Protection against MPP+ neurotoxicity in cerebellar granule cells by antioxidants.

    abstract：:The neuropathology associated with Parkinson's disease (PD) is thought to involve excessive production of free radicals, dopamine autoxidation, defects in glutathione peroxidase expression, attenuated levels of reduced glutathione, altered calcium homeostasis, excitotoxicity and genetic defects in mitochondrial comple...

    journal_title：Cell biology international

    pub_type： 杂志文章

    doi：10.1016/j.cellbi.2004.03.005

    authors： González-Polo RA,Soler G,Rodríguezmartín A,Morán JM,Fuentes JM

    更新日期：2004-01-01 00:00:00

  • Angelica sinensis polysaccharide inhibits proliferation, migration, and invasion by downregulating microRNA-675 in human neuroblastoma cell line SH-SY5Y.

    abstract：:Neuroblastoma is the most common tumor diagnosed in children and infants, with high recurrence and poor prognosis. Angelica sinensis polysaccharide (AP) whose average molecular weight is 72,900 Da possesses various bioactivities. We aimed to explore the effects of AP on neuroblastoma SH-SY5Y cells as well as the under...

    journal_title：Cell biology international

    pub_type： 杂志文章

    doi：10.1002/cbin.10954

    authors： Yang J,Shao X,Jiang J,Sun Y,Wang L,Sun L

    更新日期：2018-07-01 00:00:00

  • Examination of actin polymerization and viscosity induced by cations and ionic strength when cross-linked by alpha-actinin.

    abstract：:Increasing potassium chloride concentration from 0 to 100 mM and magnesium chloride from 0 to 2 mM show a parallel rate increase in polymerizing actin, whereas increasing calcium chloride concentration from 0 to 0.2 mM decreases the rate of polymerizing actin. The presence of alpha-actinin has little influence on the ...

    journal_title：Cell biology international

    pub_type： 杂志文章

    doi：10.1006/cbir.2002.0898

    authors： Goldmann WH

    更新日期：2002-01-01 00:00:00

  • Dendritic cell uptake of iron-based magnetic nanoparticles.

    abstract：:We have investigated the internalization of magnetic nanoparticles (NPs) into dendritic cells (DCs) in order to assess both the final location of the particles and the viability of the cultured cells. The particles, consisting of a metallic iron core covered with carbon, showed no toxic effects on the DCs and had no e...

    journal_title：Cell biology international

    pub_type： 杂志文章

    doi：10.1016/j.cellbi.2008.04.001

    authors： Goya GF,Marcos-Campos I,Fernández-Pacheco R,Sáez B,Godino J,Asín L,Lambea J,Tabuenca P,Mayordomo JI,Larrad L,Ibarra MR,Tres A

    更新日期：2008-08-01 00:00:00

  • Heat shock protein 27 expression in the human testis showing normal and abnormal spermatogenesis.

    abstract：:Heat shock proteins (HSPs) are molecular chaperones involved in protein folding, assembly and transport, and which play critical roles in the regulation of cell growth, survival and differentiation. We set out to test the hypothesis that HSP27 protein is expressed in the human testes and its expression varies with the...

    journal_title：Cell biology international

    pub_type： 杂志文章

    doi：10.1016/j.cellbi.2008.07.009

    authors： Adly MA,Assaf HA,Hussein MR

    更新日期：2008-10-01 00:00:00

  • High resolution scanning force microscopy of cardiac myocytes.

    abstract：:The advent of scanning probe microscopy has introduced a powerful new method of probing the structural features of biological specimens. In this study, high resolution atomic force microscopy micrographs of single, isolated, cardiac myocytes are presented. Significantly, our images show not only the features to be exp...

    journal_title：Cell biology international

    pub_type： 杂志文章

    doi：10.1006/cbir.2001.0813

    authors： Davis JJ,Hill HA,Powell T

    更新日期：2001-01-01 00:00:00

  • Transcription factor XBP-1 is expressed during osteoblast differentiation and is transcriptionally regulated by parathyroid hormone (PTH).

    abstract：:X-box-binding protein 1 (XBP-1) is a basic-region leucine zipper protein in the cyclic AMP response element binding protein/activating transcription factor (CREB/ATF) family of transcription factors involved in different cell-differentiation processes. We have investigated the expression of XBP-1 in differentiating MC...

    journal_title：Cell biology international

    pub_type： 杂志文章

    doi：10.1016/j.cellbi.2005.03.018

    authors： Zambelli A,Mongiardini E,Villegas SN,Carri NG,Boot-Handford RP,Wallis GA

    更新日期：2005-08-01 00:00:00

  • Inhibition of acid-sensing ion channels by amiloride protects rat articular chondrocytes from acid-induced apoptosis via a mitochondrial-mediated pathway.

    abstract：:A significant decrease in tissue pH or acidosis is a common feature of numerous diseases, including RA (rheumatoid arthritis). Cartilage homoeostasis is profoundly affected by local acidosis in the joints. The diuretic, amiloride, is neuroprotective in models of cerebral ischaemia, a property attributable to the inhib...

    journal_title：Cell biology international

    pub_type： 杂志文章

    doi：10.1042/CBI20110432

    authors： Rong C,Chen FH,Jiang S,Hu W,Wu FR,Chen TY,Yuan FL

    更新日期：2012-07-01 00:00:00

  • Inflammation: a novel mechanism for the transport of extracellular nucleotide-induced arachidonic acid by S100A8/A9 for transcellular metabolism.

    abstract：:Extracellular nucleotides cause neutrophil degranulation by activating the purinergic receptor subtype P2Y. However, the molecular mechanism involved in the signal pathway remains unknown. A hypothetical scheme suggesting that leukotriene(s) and leukotriene receptor(s) activation is required for extracellular nucleoti...

    journal_title：Cell biology international

    pub_type： 杂志文章

    doi：10.1016/s1065-6995(03)00082-9

    authors： Kannan S

    更新日期：2003-01-01 00:00:00

  • Discrepant effects of mammalian factors on molluscan cell motility, chemotaxis and phagocytosis: divergent evolution or finely tuned contingency?

    abstract：:Cell motility, cell migration and phagocytosis are distinct, though frequently sequential, processes. They are fundamental for the maintenance of homoeostasis in single cells as well as in pluricellular organisms. Like vertebrates, invertebrate immune functions are strictly dependent on cell motility, chemotaxis and p...

    journal_title：Cell biology international

    pub_type： 杂志文章,评审

    doi：10.1042/CBI20100514

    authors： Malagoli D,Ottaviani E

    更新日期：2010-11-01 00:00:00

  • Expression of osteoclastogenic factor transcripts in osteoblast-like UMR-106 cells after exposure to FGF-23 or FGF-23 combined with parathyroid hormone.

    abstract：:As a bone-derived hormone, fibroblast growth factor-23 (FGF-23) negatively regulates phosphate and calcium metabolism, while retaining growth-promoting action for mesenchymal cell differentiation. Elevated FGF-23 levels, together with hyperparathyroidism, are often observed in chronic kidney disease, which is associat...

    journal_title：Cell biology international

    pub_type： 杂志文章

    doi：10.1002/cbin.10573

    authors： Teerapornpuntakit J,Wongdee K,Krishnamra N,Charoenphandhu N

    更新日期：2016-03-01 00:00:00

  • Molecular identification of PpHDAC1, the first histone deacetylase fron the slime mold Physarum polycephalum.

    abstract：:The dynamic state of post-translational acetylation of eukaryotic histones is maintained by histone acetyltransferases (HATs) and histone deacetylases (HDACs). HATs and HDACs have been shown to be components of various regulatory protein complexes in the cell. Their enzymatic activities, intracellular localization and...

    journal_title：Cell biology international

    pub_type： 杂志文章

    doi：10.1016/s1065-6995(02)90933-9

    authors： Brandtner EM,Lechner T,Loidl P,Lusser A

    更新日期：2002-01-01 00:00:00

  • Fibrin clots keep non-adhering living cells in place on glass for perfusion or fixation.

    abstract：:We describe a method to hold living cells in place that ordinarily do not adhere to glass coverslips. The method, developed for insect spermatocytes but with application to other cell types, consists of embedding cells in a fibrin clot that forms after the enzyme thrombin cleaves the blood protein fibrinogen. The meth...

    journal_title：Cell biology international

    pub_type： 杂志文章

    doi：10.1016/j.cellbi.2005.04.010

    authors： Forer A,Pickett-Heaps J

    更新日期：2005-09-01 00:00:00

  • Substrate-induced polarisation of cultured epitheliocytes and fibroblasts: non-reactivity of Ras-transformed cells.

    abstract：:Non-transformed epitheliocytes and fibroblasts undergo modulations between the less polarised and more polarised phenotypes depending on the nature of the substrate. In contrast, transformed cells express polarised phenotype regardless of the substrate. ...

    journal_title：Cell biology international

    pub_type： 杂志文章

    doi：10.1006/cbir.2001.0776

    authors： Moizhess TG,Vasiliev JM

    更新日期：2001-01-01 00:00:00

  • The significance of alpha 5 beta 1 integrin dependent and independent actin cytoskelton organization in cell transformation and survival.

    abstract：:Cell-matrix and cell-cell interactions are important physiological determinants of cell growth, survival and transformation. Cell adhesion to the extra cellular matrix (ECM) via integrins also crucially influences the organization of the cytoskeleton. It triggers a cascade of intracellular biochemical events, which re...

    journal_title：Cell biology international

    pub_type： 杂志文章

    doi：10.1006/cbir.2002.0964

    authors： Rajeswari J,Pande G

    更新日期：2002-01-01 00:00:00