Inhibition of Ca2+/calmodulin-dependent protein kinase or epidermal growth factor receptor tyrosine kinase abolishes lysophosphatidic acid-mediated DNA-synthesis in human myometrial smooth muscle cells.

abstract：:Bradykinin (1 microM) and histamine (100 microM) evoked an initial transient increase and a subsequent sustained increase in intracellular Ca(2+) concentration ([Ca(2+)](i)) in fura-2-loaded human gingival fibroblasts, which may be attributed to Ca(2+) release from intracellular stores and Ca(2+) entry from extracellu...

journal_title：Cell biology international

authors： Ogata Y,Nakao S,Shimizu E,Matsuda-Honjyo Y,Yamazaki M,Furuyama S,Sugiya H

更新日期：2003-01-01 00:00:00

abstract：:Having the ability to control cell behaviour would be of great advantage in tissue engineering. One method of gaining control over cell adhesion, proliferation, guidance and differentiation is use of topography. Whilst it has be known for some time that cells can be guided by micro-topography, it is only recently beco...

journal_title：Cell biology international

authors： Dalby MJ,Riehle MO,Johnstone H,Affrossman S,Curtis AS

更新日期：2004-01-01 00:00:00

abstract：:CLIC5 (chloride intracellular channel 5) is a CLIC (chloride intracellular channel) with various functions. Its high expression in skeletal muscle and association with actin-based cytoskeleton suggests that it may play an important role in muscle tissue. This study was conducted to examine whether CLIC5 regulates the ...

journal_title：Cell biology international

authors： Li F,Yin J,Yue T,Liu L,Zhang H

更新日期：2010-03-08 00:00:00

abstract：:A number of pathophysiological conditions are related to iron metabolism disturbances. Some of them are well known, others are newly discovered or special. Hepcidin is a newly identified iron metabolism regulating hormone, which could be a promising biomarker for many disorders. In this review, we provide background i...

journal_title：Cell biology international

authors： Miseta A,Nagy J,Nagy T,Poór VS,Fekete Z,Sipos K

更新日期：2015-11-01 00:00:00

abstract：:Here we report a homologue of the apolipoprotein D gene (AmphiApoD) in amphioxus, Branchiostoma belcheri tsingtauense, the first such finding in a basal chordate cephalochordate. The main features of the protein predicted from AmphiApoD are characteristic of the apolipoprotein D. Phylogenetic analysis places AmphiApoD...

journal_title：Cell biology international

authors： Wang L,Zhang S,Liu Z,Li H,Wang Y,Jiang S

更新日期：2007-01-01 00:00:00

abstract：:Hyperglycemia is one of the most important pathogenesis of diabetic osteopathy. Several lines of studies indicate Runx2 plays a critical role in the process of osteogenic differentiation. However, little studies have analyzed the effect of Runx2 on osteoblast differentiation of rat bone mesenchymal stem cells (rBMSCs)...

journal_title：Cell biology international

authors： Chen Y,Hu Y,Yang L,Zhou J,Tang Y,Zheng L,Qin P

更新日期：2017-08-01 00:00:00

abstract：:The advent of scanning probe microscopy has introduced a powerful new method of probing the structural features of biological specimens. In this study, high resolution atomic force microscopy micrographs of single, isolated, cardiac myocytes are presented. Significantly, our images show not only the features to be exp...

journal_title：Cell biology international

authors： Davis JJ,Hill HA,Powell T

更新日期：2001-01-01 00:00:00

abstract：:Normal human bone marrow stroma cells include stem cells for both haemopoietic and osteochondrogenic lineages and express both bone morphogenetic protein (BMP) type I and type II receptors. As a member of the TGF-beta super-family, BMP-6 binds to both BMP type I and type II receptors and is involved in the development...

journal_title：Cell biology international

authors： Ahmed N,Sammons J,Carson RJ,Khokher MA,Hassan HT

更新日期：2001-01-01 00:00:00

abstract：:The effects of cadmium Cd (II) ions on the physiology and biological activity of Trametes versicolor, a strain belonging to white-rotting Basidiomycetes, were examined. Cd (II) ions were added to 10-day-old cultures grown on a liquid medium, or at the time of inoculation. Our experiments showed that T. versicolor is a...

journal_title：Cell biology international

authors： Jarosz-Wilkolazka A,Malarczyk E,Pirszel J,Skowroński T,Leonowicz A

更新日期：2002-01-01 00:00:00

abstract：:To examine cytokine production in response to RSV infection, we assessed the levels of 29 cytokines released from RSV-infected human foetal lung fibroblasts. We also examined the relationships between the effects of fluticasone propionate and various signalling pathways in the cells. Twenty-four hours after infection ...

journal_title：Cell biology international

authors： Seki E,Yoshizumi M,Tanaka R,Ryo A,Ishioka T,Tsukagoshi H,Kozawa K,Okayama Y,Okabe-Kado J,Goya T,Kimura H

更新日期：2013-04-01 00:00:00

abstract：:Mitomycin C (MMC) treatment has been used to arrest cell proliferation but not much is known about the effect of MMC on human foreskin fibroblasts (HFF) used as feeders for human embryonic stem cells (hESC). We tested the ability of MMC to stop the proliferation of HFF and to induce apoptosis. MMC inhibited the prolif...

journal_title：Cell biology international

authors： Nieto A,Cabrera CM,Catalina P,Cobo F,Barnie A,Cortés JL,Barroso del Jesus A,Montes R,Concha A

更新日期：2007-03-01 00:00:00

abstract：:Previous trials performed in our laboratory have demonstrated that stainless steel corrosion products induced morphological changes in mice seminiferous cells. In this study the functional nature of the blood-testis barrier was investigated, in view of the extensive use of this metallic alloy in orthopaedic surgery. T...

journal_title：Cell biology international

authors： Pereira ML

更新日期：1995-07-01 00:00:00

abstract：:Grafting material for vaginal reconstruction commonly includes the bowel, peritoneum, skin, and amniotic membrane. Bone marrow mesenchymal stem cells (MSCs) have the potential of multilineage differentiation into a variety of cells and have been widely explored in tissue engineering. In the current study, we examined ...

journal_title：Cell biology international

authors： Li Y,Liu F,Zhang Z,Zhang M,Cao S,Li Y,Zhang L,Huang X,Xu Y

更新日期：2015-11-01 00:00:00

abstract：:Polycystin-2 (PC-2), a protein encoded by PKD2 and involved in autosomal dominant polycystic kidney disease (ADPKD), is a non-selective cationic channel recently implicated in the function of primary cilia. We recently constructed a new animal model in the form of a transgenic mouse with a BAC-containing human PKD2 in...

journal_title：Cell biology international

authors： Burtey S,Riera M,Ribe E,Pennenkamp P,Rance R,Luciani J,Dworniczak B,Mattei MG,Fontés M

更新日期：2008-10-01 00:00:00

abstract：:Immunocytochemical staining of citrulline-containing proteins, i.e. products of endogenous peptidylarginine deiminase (EC 3.5.3.15) reaction, has been performed by chemical modification of citrulline residues in situ, followed by probing with IgG specific to the modified residues. Rat spinal cords that had been preinc...

journal_title：Cell biology international

authors： Asaga H,Senshu T

更新日期：1993-05-01 00:00:00

abstract：:To establish useful human normal cell lines, TERT (telomerase reverse transcriptase) cDNA was transfected into normal female lung fibroblast, TIG-1. After long-term-sub-cultivation of 74 individual clones selected for resistance to G418, we obtained 55 cultures with normal range of life span [75 PDL (population doubli...

journal_title：Cell biology international

authors： Kamada M,Kumazaki T,Matsuo T,Mitsui Y,Takahashi T

更新日期：2012-06-01 00:00:00

abstract：:Ca(2+)mobilization induced by ATP, isoproterenol and the Ca(2+)-ATPase inhibitor thapsigargin in the human submandibular duct cell line A253 was investigated using the Ca(2+)-sensitive fluorescent indicator fura-2. ATP and isoproterenol increased cytosolic free Ca(2+)([Ca(2+)](i)) and subsequent exposure to thapsigarg...

journal_title：Cell biology international

authors： Andersson C,Zhang AL,Roomans GM

更新日期：2000-01-01 00:00:00

abstract：:Although several species of Tetrahymena are often described as histophagous and opportunistic pathogens of fish, little is known about ciliate/fish cell interactions, but one approach for studying these is in vitro with cell lines. In this study, T. thermophila, B1975 (wild type) and NP1 (temperature sensitive mutant ...

journal_title：Cell biology international

authors： Pinheiro MD,Bols NC

更新日期：2014-10-01 00:00:00

abstract：:In the present study, we investigated the effects of tetramethylpyrazine (TMP) on hydrogen peroxide (H2O2)-induced apoptosis in PC12 cells. The apoptosis in H2O2-induced PC12 cells was accompanied by a decrease in Bcl-2/Bax protein ratio, release of cytochrome c to cytosol and the activation of caspase-3. TMP not only...

journal_title：Cell biology international

authors： Cheng XR,Zhang L,Hu JJ,Sun L,Du GH

更新日期：2007-05-01 00:00:00

abstract：:Conventional kinesin is an ATPase-active motor protein that is involved in the microtubule-dependent transport of cytoplasmic cargoes. The present paper provides a condensed overview on kinesin-1 and its motility generation outside a living cell. Moreover, it demonstrates that the neuron-specific kinesin KIF5A enables...

journal_title：Cell biology international

authors： Böhm KJ

更新日期：2008-05-01 00:00:00

abstract：:Human tissues are sophisticated ensembles of various distinct cell types encapsulated in the biomechanical cues of the extracellular matrix. It has been known matrix stiffness plays a pivot role in cellular events and tissue-scale biological processes. Thus, materials that can mimic mechanical environments of tissues ...

journal_title：Cell biology international

authors： Zhao H,Xu K,Zhu P,Wang C,Chi Q

更新日期：2019-02-01 00:00:00

abstract：:Almost universally, the effective stimulus for mammalian 9+0 primary cilia has been taken to be bending. In this article I point out that in several physiological contexts there is great advantage in detecting pressure differences across the cell wall, i.e. axially directed forces pushing fluid to and fro through the ...

journal_title：Cell biology international

authors： Bell A

更新日期：2008-04-01 00:00:00

abstract：:The exon 16-encoded juxtamembrane (JM) domain of human insulin receptor (hIR) harbors the NPEY motif which couples the insulin-activated hIR kinase to downstream signal transduction molecules. We sought to determine if signal transduction requires the entire exon 16-encoded 22-amino acid JM domain. Transfected CHO cel...

journal_title：Cell biology international

authors： Sattar AA,Berhanu C,Gebreselassie S,Berhanu P

更新日期：2007-08-01 00:00:00

abstract：:ZO-1 is a peripheral protein that plays a central role in the macromolecular assembly of tight junctions by interacting with integral proteins (occludin, claudins, JAMs) of the membrane of adjoining cells, with the actin cytoskeleton, and with nuclear factors. Human ZO-1 is expressed in all epithelia and some speciali...

journal_title：Cell biology international

authors： Ciana A,Meier K,Daum N,Gerbes S,Veith M,Lehr CM,Minetti G

更新日期：2010-05-07 00:00:00

abstract：:Chloride secretion in primary cultures of cells originating from the secretory coil of human sweat glands was investigated by electron probe X-ray microanalysis. The total intracellular Cl concentration was lowered by muscarinic agonists (carbachol and acetylcholine), as well as by the calcium ionophore A23187. The mu...

journal_title：Cell biology international

authors： Mörk AC,Hongpaisan J,Roomans GM

更新日期：1995-02-01 00:00:00

abstract：:Epidermis, a continuously renewing tissue, is maintained by stem cells that proliferate and replenish worn out or damaged cells in the tissue during life. Cultured epidermal stem cells have great potential in scientific research and clinical application. However, isolating a pure and viable population of epidermal ste...

journal_title：Cell biology international

authors： Zhou JX,Jia LW,Yang YJ,Peng S,Cao YJ,Duan EK

更新日期：2004-01-01 00:00:00

abstract：:Oral squamous cell carcinoma (OSCC) is a serious global health problem. Recently, accumulating microRNA (miRNA) has emerged as crucial players in the development and progression of carcinomas including OSCC. Our study aimed to further investigate the roles of miR-140-5p in OSCC tumorigenesis and related molecular basi...

journal_title：Cell biology international

authors： Peng M,Pang C

更新日期：2019-08-08 00:00:00

abstract：:The unicellular Tetrahymena has receptors for hormones of higher vertebrates, produces these hormones, and their signal pathways are similar. The first encounter with a hormone in higher dose provokes the phenomenon of hormonal imprinting, by which the reaction of the cell is quantitatively modified. This modification...

journal_title：Cell biology international

authors： Kőhidai L,Lajkó E,Pállinger E,Csaba G

更新日期：2012-10-01 00:00:00

abstract：:Vascular endothelial growth factor (VEGF) plays a key role in formation of pleural effusions and in tumorigenesis and progression of malignant mesothelioma. Mesothelial cells (MC) express the viral receptors Toll-like receptor 3 (TLR3), RIG-I and MDA5. Activation of these receptors by viral RNA exemplified by poly(I:C...

journal_title：Cell biology international

authors： Wörnle M,Sauter M,Kastenmüller K,Ribeiro A,Roeder M,Mussack T,Ladurner R,Sitter T

更新日期：2009-02-01 00:00:00

abstract：:To identify the molecular basis by which nonpermissive temperature (NPT) induces cell differentiation in Sertoli TTE3 cells harboring temperature-sensitive SV40 large T-antigen, we performed global scale microarray and computational gene network analyses. In TTE3 cells, inactivation of the large T-antigen by a NPT at ...

journal_title：Cell biology international

authors： Tabuchi Y,Takasaki I,Suto A,Kondo T,Suzuki Y,Obinata M

更新日期：2007-10-01 00:00:00