Centrosome overduplication and mitotic instability in PKD2 transgenic lines.

abstract：:We review Don Gilbert's pioneering seminal contributions that both detailed the mathematical principles and the experimental demonstration of several of the key dynamic characteristics of life. Long before it became evident to the wider biochemical community, Gilbert proposed that cellular growth and replication neces...

journal_title：Cell biology international

authors： Gilbert K,Hammond KD,Brodsky VY,Lloyd D

更新日期：2020-06-01 00:00:00

abstract：:Adipose tissue is a potential site of retinoic acid (RA) action, but its physiological significance remains to be clarified. We have examined the effect of all-trans retinoic acid (ATRA) on growth and differentiation of preadipocytes, and on adipokine gene expression in mature adipocytes using human preadipocyte cell ...

journal_title：Cell biology international

authors： Morikawa K,Hanada H,Hirota K,Nonaka M,Ikeda C

更新日期：2013-01-01 00:00:00

abstract：:Type I diabetes is characterized by the deficiency of endocrine beta cells in the pancreatic islets of Langerhans and transplantation of islet cells can be an effective therapeutic approach. Embryonic stem cells can be differentiated into any cell type, and therefore represent an unlimited source of islet cells for th...

journal_title：Cell biology international

authors： Chen C,Zhang Y,Sheng X,Huang C,Zang YQ

更新日期：2008-04-01 00:00:00

abstract：:The mdx mouse has been used as an animal model for human Duchenne muscular dystrophy (DMD). Unlike DMD, skeletal muscles of mdx mice undergo successful regeneration and do not show extensive fibrosis and functional impairment. Growth factors have been proposed to be involved in muscle growth and regeneration. We compa...

journal_title：Cell biology international

authors： Chen G,Bressler BH,Quinn LS

更新日期：1994-04-01 00:00:00

abstract：:Oxidative stress can be defined as the increase of oxidizing agents like reactive oxygen and nitrogen species, or the imbalance between the antioxidative defense mechanism and oxidants. Cell cycle checkpoint response can be defined as the arrest of the cell cycle functioning after damaging chemical exposure. This temp...

journal_title：Cell biology international

authors： Akcakaya H,Dal F,Tok S,Cinar SA,Nurten R

更新日期：2015-02-01 00:00:00

abstract：:Hepatic heat shock protein Hsp70 synthesis and in vitro phosphorylation were studied in the liver cytosol of intact, adrenalectomized and dexamethasone-administered adrenalectomized rats after 41 degrees C whole body hyperthermic stress. Hsp70 was detected by immunoblotting with N27F3-4 monoclonal antibody recognizing...

journal_title：Cell biology international

authors： Cvoro A,Dundjerski J,Trajković D,Matić G

更新日期：1999-01-01 00:00:00

abstract：:Zebularine is a cytidine analogue incorporated into DNA during replication, inhibiting DNA methyltransferase 1 (DNMT1), resulting in demethylation and changes in gene expression. Such modification may improve radiosensitivity in resistant lymphoma cells. The hypothesis of this study was that zebularine and radiation w...

journal_title：Cell biology international

authors： Bryan JN,Kumar SR,Jia F,Balkin ER,Lewis MR

更新日期：2014-02-01 00:00:00

abstract：:Embryonic development depends on the normal invasion of trophoblast cells. Forkhead box C2 (FOXC2) is a member of Forkhead box family, which is involved in the tumor cells invasion. The aim of this study was to explore the roles of FOXC2 on the invasion of human trophoblast cells, and further study its molecular mecha...

journal_title：Cell biology international

authors： Zhang Y,Zhang Y

更新日期：2018-07-01 00:00:00

abstract：:Following genotoxic insult, p53 mutated tumour cells undergo mitotic catastrophe. This is characterised by a switch from mitosis to the endocycle. The essential difference between mitosis and the endocycle is that in the latter, DNA synthesis is uncoupled from cell division, which leads to the formation of endopolyplo...

journal_title：Cell biology international

authors： Erenpreisa J,Kalejs M,Cragg MS

更新日期：2005-12-01 00:00:00

abstract：:Forms of the protozoan of the Hepatozoon genus are detected free in the circulation and also within some of the erythrocytes of infected snakes. In healthy snakes, DNA fragmentation and cell death usually affect a few circulating erythrocytes in agreement with the long life span expected for these cells. In the presen...

journal_title：Cell biology international

authors： Miyamoto M,Mello ML

更新日期：2007-05-01 00:00:00

abstract：:Bcl-2 family proteins play a critical role in the regulation of apoptosis. Treatment of a human hepatocellular carcinoma cell line, QGY-7703, with Taxol induced apoptosis and Bcl-2 protein phosphorylation. Microscopic observation indicated that apoptotic bodies (0-15%) of Taxol-treated QGY cells appeared after 12 h of...

journal_title：Cell biology international

authors： Cheng SC,Luo D,Xie Y

更新日期：2001-01-01 00:00:00

abstract：:This review summarizes original and literature data on changes in the ultrastructure of major cell organelles during apoptosis obtained by transmission electron microscopy. Organelles that make the most crucial contribution to the initiation of apoptosis: plasma membrane, mitochondria, proteasomes, Golgi apparatus, an...

journal_title：Cell biology international

authors： Snigirevskaya ES,Komissarchik YY

更新日期：2019-07-01 00:00:00

abstract：:Genistein is an isoflavone that has estrogen (E2 )-like activity and is beneficial for follicular development, but little is known regarding its function in oxidative stress (OS)-mediated granulosa cell (GC) injury. Here, we found that after exposure to H2 O2 , Genistein weakened the elevated levels of intracellular r...

journal_title：Cell biology international

authors： Luo M,Yang ZQ,Huang JC,Wang YS,Guo B,Yue ZP

更新日期：2020-02-01 00:00:00

abstract：:As embryonic progenitors for the gametes, PGCs (primordial germ cells) proliferate and develop under strict regulation of numerous intrinsic and external factors. As the most active natural metabolite of vitamin A, all-trans RA (retinoic acid) plays pivotal roles in regulating development of various cells. The prolife...

journal_title：Cell biology international

authors： Yu M,Ge C,Zeng W,Mi Y,Zhang C

更新日期：2012-08-01 00:00:00

abstract：:Emerging evidence suggests that miR-143 plays an important role in the regulation of tumor sensitivity to chemotherapeutic agents. The study explores the underlying mechanism of miR-143 in reversing cisplatin resistance in ovarian cancer. The cisplatin-resistant ovarian cancer cell line A2780/CDDP was induced and esta...

journal_title：Cell biology international

authors： Han X,Liu D,Zhou Y,Wang L,Hou H,Chen H,Zhang L,Chen W,Li X,Zhao L

更新日期：2021-01-01 00:00:00

abstract：:The authors examined the growth response of cardinal ligamental fibroblasts derived from patients with prolapsus uteri (HPLiF) and compared it with the response of those from control subjects (HCLiF). The growth rate during the logarithmic growth phase was not different between HPLiF and HCLiF, while the cell density ...

journal_title：Cell biology international

authors： Yamamoto M,Aoyagi M,Akazawa K,Tajima S,Yamamoto K

更新日期：1998-01-01 00:00:00

abstract：:The influence of oxygen tension on the side population (SP) fraction sorted from ATDC5 chondroprogenitor cells was investigated. ATDC5 cells cultured in normoxia (20%) or hypoxia (1% oxygen) were compared. The SP fraction was significantly higher in the cells cultured in hypoxia. The gene expression of 3 ABC transport...

journal_title：Cell biology international

authors： Kishimoto KN,Oxford CL,Reddi AH

更新日期：2009-12-01 00:00:00

abstract：:To examine cytokine production in response to RSV infection, we assessed the levels of 29 cytokines released from RSV-infected human foetal lung fibroblasts. We also examined the relationships between the effects of fluticasone propionate and various signalling pathways in the cells. Twenty-four hours after infection ...

journal_title：Cell biology international

authors： Seki E,Yoshizumi M,Tanaka R,Ryo A,Ishioka T,Tsukagoshi H,Kozawa K,Okayama Y,Okabe-Kado J,Goya T,Kimura H

更新日期：2013-04-01 00:00:00

abstract：:Coumarin and its derivative 7-hydroxycoumarin (7-OHC) have antitumor and antimetastatic properties. The purpose of this study was to investigate the possible effects of these compounds on expression of the bcl-2 and Bax oncoproteins in two human lung cancer cell lines, A427 and Calu-1. The cells were cultured in vitro...

journal_title：Cell biology international

authors： Elinos-Báez CM,León F,Santos E

更新日期：2005-08-01 00:00:00

abstract：:Epigenetic silencing of cancer-related genes by abnormal methylation and the reversal of this process by DNA methylation inhibitors represents a promising strategy in cancer therapy. As DNA methylation affects gene expression and chromatin structure, we investigated the effects of novel DNMT (DNA methyltransferase) in...

journal_title：Cell biology international

authors： Savickiene J,Treigyte G,Jazdauskaite A,Borutinskaite VV,Navakauskiene R

更新日期：2012-11-01 00:00:00

abstract：:Treatment of cultured rat osteoblasts with staurosporine caused a rapid outgrowth of long slender cellular processes and the formation of stellate cells. The number of stellate cells increased with higher concentrations of and longer incubation with staurosporine. Scanning electron microscopy (SEM) revealed that the s...

journal_title：Cell biology international

authors： Yang RS,Lu KS,Fu WM,Liu TK,Lin-Shiau SY

更新日期：1993-01-01 00:00:00

abstract：:Ischemic stroke is a major common cause of death and long-term disability worldwide. Several pathophysiological events including excitotoxicity, oxidative/nitrative stress, inflammation, and apoptosis are involved in ischemic injuries. Recently, the molecular mechanisms involved in cerebral ischemia through a focus on...

journal_title：Cell biology international

authors： Behdarvandy M,Karimian M,Atlasi MA,Azami Tameh A

更新日期：2020-02-01 00:00:00

abstract：:Non-specific L-type calcium channel blockers, such as verapamil (> or =50 microM), induce metaphase-II (M-II) arrest and apoptosis in aged rat eggs cultured in Ca(2+)-deficient medium. However, the effects of extracellular Ca(2+) on verapamil-induced M-II arrest and apoptosis have not yet been reported. We have demons...

journal_title：Cell biology international

authors： Chaube SK,Tripathi A,Khatun S,Mishra SK,Prasad PV,Shrivastav TG

更新日期：2009-03-01 00:00:00

abstract：:Immunocytochemical staining of citrulline-containing proteins, i.e. products of endogenous peptidylarginine deiminase (EC 3.5.3.15) reaction, has been performed by chemical modification of citrulline residues in situ, followed by probing with IgG specific to the modified residues. Rat spinal cords that had been preinc...

journal_title：Cell biology international

authors： Asaga H,Senshu T

更新日期：1993-05-01 00:00:00

abstract：:The present study aimed to investigate the potassium currents and further explore the role of potassium channels in drug response of gastric cancer cells. By patch-clamp technique, potassium currents of human gastric cancer cell SGC7901 were recorded in the mode of voltage clamp. Both 4-aminopyridine (4-AP) and tetrae...

journal_title：Cell biology international

authors： Han Y,Shi Y,Han Z,Sun L,Fan D

更新日期：2007-07-01 00:00:00

abstract：:Tripartite motif-containing 22 (TRIM22) is reported to participate in numerous cellular activities. Recent studies confirm that TRIM22 is a target gene for P53, and inhibits clonogenic growth of leukemic U-937 cells. The current study aims to discover the effect of TRIM22 in progression of human chronic myeloid leukem...

journal_title：Cell biology international

authors： Li L,Qi Y,Ma X,Xiong G,Wang L,Bao C

更新日期：2018-09-01 00:00:00

abstract：:The formation of vertebrate skeletal muscles widely thought to be under the control of hierarchy of regulatory genes. MYF5 is one of the myogenic determination gene expressed in the developing mouse dermomyotome which control skeletal muscle differentiation. In the current work, we had obtained the cDNA sequence inclu...

journal_title：Cell biology international

authors： Nie YW,Ding XB,Ge XG,Fan HL,Liu ZW,Guo H

更新日期：2013-09-01 00:00:00

abstract：:Mutants of the methanol-utilizing yeast Pichia pastoris and the alkane-utilizing yeast Yarrowia lipolytica defective in the orthologue of UGT51 (encoding sterol glucosyltransferase) were isolated and compared. These mutants do not contain the specific ergosterol derivate, ergosterol glucoside. We observed that the P. ...

journal_title：Cell biology international

authors： Stasyk OV,Nazarko TY,Stasyk OG,Krasovska OS,Warnecke D,Nicaud JM,Cregg JM,Sibirny AA

更新日期：2003-01-01 00:00:00

abstract：:FITC-insulin binding to previously hormone-treated Tetrahymena was studied by flow cytometry and confocal microscopy. Hormones produced by Tetrahymena were chosen for study and the hormone concentrations were administered between 10(-6) and 10(-21)M for 30 min. Endorphin, serotonin and insulin significantly reduced th...

journal_title：Cell biology international

authors： Csaba G,Kovács P,Tóthfalusi L,Pállinger E

更新日期：2006-12-01 00:00:00

abstract：:The cytokertatins in respiratory epithelial cells (REC) of human nasal polyps and turbinates were analyzed by immunohistochemistry. Cytokeratin 19 (CK19) was present in all REC, CK5 and 14 were expressed primarily in basal cells, and CK7, 8, and 18 were found in suprabasal cells. Differences in cytoplasmic locations w...

journal_title：Cell biology international

authors： Hicks W Jr,Ward R,Edelstein D,Hall L 3rd,Albino A,Hard R,Asch B

更新日期：1995-04-01 00:00:00