Effects of coumarin and 7OH-coumarin on bcl-2 and Bax expression in two human lung cancer cell lines in vitro.

abstract：:Insulin-like growth factor-1 (IGF-1) is a positive regulator in proliferation and differentiation of skeletal muscle cells, while myostatin (MSTN) is a member of transforming growth factor beta superfamily that acts as a negative regulator of skeletal muscle mass. The present study was performed to detail whether a co...

journal_title：Cell biology international

authors： Miyake M,Hayashi S,Sato T,Taketa Y,Watanabe K,Hayashi S,Tanaka S,Ohwada S,Aso H,Yamaguchi T

更新日期：2007-10-01 00:00:00

abstract：:DNA is constantly being damaged, either by endogenous or exogenous genotoxins. In that regard, DNA repair activities are essential for maintaining genomic stability and to life itself. Mutations in genes encoding DNA repair proteins cause severe human syndromes, but DNA repair defects have also been linked to several ...

journal_title：Cell biology international

authors： Prates Mori M,de Souza-Pinto NC

更新日期：2018-06-01 00:00:00

abstract：:Temperature of culture can be used to modulate cellular metabolism for improving small intestinal cell culture and cryopreservation. An hypothermia pretreatment (2 days at 25 degrees C and 3 hours recovery at 37 degrees C) improved hamster cell survival to freeze-thaw damage (p < 0.01) but decreased the survival of 2 ...

journal_title：Cell biology international

authors： Kaeffer B,Uriel IG,Bottreau E

更新日期：1994-11-01 00:00:00

abstract：:Neural stem cells (NSCs) are currently considered powerful candidates for cell therapy in neurodegenerative disorders such as Parkinson's disease. However, it is not known when and how NSCs begin to differentiate functionally. Recent reports suggest that classical neurotransmitters such as acetylcholine (Ach) are invo...

journal_title：Cell biology international

authors： Zhou C,Wen ZX,Shi DM,Xie ZP

更新日期：2004-01-01 00:00:00

abstract：:Previous trials performed in our laboratory have demonstrated that stainless steel corrosion products induced morphological changes in mice seminiferous cells. In this study the functional nature of the blood-testis barrier was investigated, in view of the extensive use of this metallic alloy in orthopaedic surgery. T...

journal_title：Cell biology international

authors： Pereira ML

更新日期：1995-07-01 00:00:00

abstract：:The purpose of this study was three fold: (1) to reveal the implications of Wnt5A for cytokine and chemokine production by human ovarian cancer cell line SKOV-3 cells, (2) to determine the influence of Wnt5A on chemotactic SKOV-3 cell migration, and (3) to assess the effect of inflammatory mediators on Wnt5A expressio...

journal_title：Cell biology international

authors： Arabzadeh S,Hossein G,Zarnani AH

更新日期：2016-02-01 00:00:00

abstract：:The biosynthesis of interleukin-6 receptor (IL-6R) and gp130 in vitro was blocked using specific antisense oligonucleotides (ASO) in HepG2 liver cells and the efficacy of various ASOs was tested on the generation of IL-6-induced junB mRNA. We used three ASOs specific for the IL-6 receptor, three specific for gp130 and...

journal_title：Cell biology international

authors： Varga VL,Fülöp AK,Holub MC,Tóth S,Szalai C,Falus A

更新日期：2001-01-01 00:00:00

abstract：:The focal adhesion protein vinculin has been implicated in associating with soluble and membranous phospholipids. Detailed investigations over the past ten years describe the intermolecular interactions of the vinculin tail domain with soluble and membrane phospholipids. Previous studies have implied that the tail's u...

journal_title：Cell biology international

authors： Goldmann WH

更新日期：2018-08-01 00:00:00

abstract：:Fgf8 is a member of the fibroblast growth factor (FGF) family that plays an important role in early neural development. Cellular aggregation and retinoic acid (RA) are needed for mouse embryonic carcinoma (EC) P19 cell neural differentiation. We have examined the Fgf8 gene in P19 cells during neural differentiation an...

journal_title：Cell biology international

authors： Alam AH,Suzuki H,Tsukahara T

更新日期：2009-09-01 00:00:00

abstract：:Local anesthetic of bupivacaine may inhibit neurite outgrowth and induce apoptosis in mouse dorsal root ganglia (DRG) neurons. In this work, we intended to investigate the functional role of microRNA 26a (miR-26a) in regulating bupivacaine-induced nerve injury in DRG neurons. DRG neurons were extracted from C57BL/6 mi...

journal_title：Cell biology international

authors： Cui C,Xu G,Qiu J,Fan X

更新日期：2015-08-01 00:00:00

abstract：:Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) gains access to host cells by attaching to angiotensin-converting enzyme 2 (ACE2). Vitamin D (VitD) can upregulate ACE2 and has an antagonistic effect on Renin, which exerts a vasodilatation and anti-inflammatory effect against coronavirus disease (COVID-19)...

journal_title：Cell biology international

authors： Shojaeefar E,Malih N,Rezaei N

更新日期：2021-01-01 00:00:00

abstract：:Properly metabolized globin synthesis and iron uptake are indispensable for erythroid cell differentiation and maturation. Mitochondrial participation is crucial in the process of haeme synthesis for cytochromes and haemoglobin. We studied the final biosynthesis site of haemoglobin using an ultrastructural approach, w...

journal_title：Cell biology international

authors： Cianciarullo AM,Bertho AL,Soares MJ,Hosoda TM,Nogueira-Silva S,Beçak W

更新日期：2003-01-01 00:00:00

abstract：:We have successfully developed both spontaneous and inductive cardiomyocyte differentiation of iPS cells reprogrammed from human foreskin fibroblasts. The reprogrammed iPS cells morphologically resemble human cardiomyocytes which can beat. RT-PCR and immunostaining show that cardiac markers are expressed that are comp...

journal_title：Cell biology international

authors： Gai H,Leung EL,Costantino PD,Aguila JR,Nguyen DM,Fink LM,Ward DC,Ma Y

更新日期：2009-11-01 00:00:00

abstract：:Cattle plays an important role in providing essential nutrients through meat production. Thus, we focused on epigenetic factors associated with meat yield. To investigate circulating miRNAs that are involved with meat yield and connect biofluids and longissimus dorsi (LD) muscle in Korean cattle, we performed analyses...

journal_title：Cell biology international

authors： Lee S,Park SJ,Cheong JK,Ko JY,Bong J,Baik M

更新日期：2017-07-01 00:00:00

abstract：:In 3D cultured cell systems, the cells form 3D spheroids that mimic cancer cell spheroids in vivo. Cancer cells form cell spheroids as they grow. The in vivo spheroids do not contain a vascular network; therefore, oxygen and nutrition supplies are insufficient. Specifically, the cells in the core region of the cluster...

journal_title：Cell biology international

authors： Terashima J,Sampei S,Iidzuka M,Ohsakama A,Tachikawa C,Satoh J,Kudo K,Habano W,Ozawa S

更新日期：2016-11-01 00:00:00

abstract：:Chloride secretion in primary cultures of cells originating from the secretory coil of human sweat glands was investigated by electron probe X-ray microanalysis. The total intracellular Cl concentration was lowered by muscarinic agonists (carbachol and acetylcholine), as well as by the calcium ionophore A23187. The mu...

journal_title：Cell biology international

authors： Mörk AC,Hongpaisan J,Roomans GM

更新日期：1995-02-01 00:00:00

abstract：:Mesenchymal stem cells (MSCs) and endothelial progenitor cells (EPCs) are attached to each other in the bone marrow (BM) cavity and in in vitro cultures, and this adhesion has important physiological significance. We demonstrated that cell proliferation could be promoted when MSCs were co-cultured with EPCs, which was...

journal_title：Cell biology international

authors： Xia J,Zhang H,Gao X,Guo J,Hou J,Wang X,Wang S,Yang T,Zhang X,Ge Q,Wan L,Cheng W,Zheng J,Chen X,Wu X

更新日期：2016-04-01 00:00:00

abstract：:Using clonal cell cultures, a significant increase in chromosomal aberrations (aneuplolidy, dicentrics and chromatid breaks) were observed in MCF-7 cells compared with HeLa. BRCA1 expression was lower in MCF-7 cells than in HeLa cells. Since BRCA1 is known to play a role in the maintenance of chromosomal integrity, th...

journal_title：Cell biology international

authors： Kachhap SK,Vetale SP,Dange P,Ghosh SN

更新日期：2001-01-01 00:00:00

abstract：:Whether fructose (FRU), as the sole energy source, confers a metabolic advantage on cancer cells against noxious stimuli is unknown. The aim of this study was to evaluate the effects of low (11 mM), moderate (25 mM), and high (55 mM) FRU concentrations alone or in combination with rotenone (ROT) or doxorubicin (DOX) i...

journal_title：Cell biology international

authors： Diaz-Aguirre V,Velez-Pardo C,Jimenez-Del-Rio M

更新日期：2016-11-01 00:00:00

abstract：:Cell therapy and regenerative medicine are potentially two of the most exciting aspects of the novel therapeutic methods currently under development. However, these treatments present a number of important biosafety issues, like the possible transmission of microorganisms to the recipients. The most common potential f...

journal_title：Cell biology international

authors： Cobo F,Cortés JL,Cabrera C,Nieto A,Concha A

更新日期：2007-09-01 00:00:00

abstract：:The purpose of the study was to examine the effect of interleukins, IL-6, IL-8, and IL-15, on insulin-mediated redistribution of Rab4a, an early endosome marker, in mouse 3T3-L1 adipocytes. The interleukins did not affect cell viability; however, cell number was slightly but significantly higher in cultures exposed to...

journal_title：Cell biology international

authors： Błaszczyk M,Gajewska M,Milewska M,Grzelkowska-Kowalczyk K

更新日期：2017-04-01 00:00:00

abstract：:The first description of intrachromosomal fibers was made by Baranetzky in 1880. Since that time, a plethora of fibrillar substructures have been described inside the mitotic chromosomes, and published data indicate that chromosomes may be formed as a result of the hierarchical folding of chromatin fibers. In this rev...

journal_title：Cell biology international

authors： Kuznetsova MA,Sheval EV

更新日期：2016-11-01 00:00:00

abstract：:Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is a key enzyme of the glycolytic pathway. Recent studies have demonstrated an additional role in apoptosis: GAPDH is targeted to the nucleus during apoptotic signalling. This nuclear transport has also been observed in serum-depleted cells, but it is reversible in fibr...

journal_title：Cell biology international

authors： Schmitz HD,Dutiné C,Bereiter-Hahn J

更新日期：2003-01-01 00:00:00

abstract：:Resistance to radiotherapy and chemotherapy has been a major problem of conventional cancer therapies, which consequently leads to cancer relapse and cancer-related death. It is known that cancer stem cells (CSCs) play a key role in therapy resistance and CSC-based targeted therapies have been considered as a powerful...

journal_title：Cell biology international

authors： Johari B,Rahmati M,Nasehi L,Mortazavi Y,Faghfoori MH,Rezaeejam H

更新日期：2020-12-01 00:00:00

abstract：:Continuous variation in the direction of the gravity vector leads to various cellular responses including modulation of gene expression. Complementary DNA (cDNA) array analyses are available to observe the variation of gene expression under different conditions. In this study, expression levels of 588 representative g...

journal_title：Cell biology international

authors： Arase Y,Nomura J,Sugaya S,Sugita K,Kita K,Suzuki N

更新日期：2002-01-01 00:00:00

abstract：:Cervical cancer is considered a common yet preventable cause of death in women. In this report, we studied the role of the NF-kappaB gene family in HeLa human cervical cancer cells, using the Xrel3 c-Rel homologue of Xenopus laevis. The expression of Xrel3/c-Rel slowed cell growth 6-fold, consistent with an upregulate...

journal_title：Cell biology international

authors： Shehata M,Shehata M,Shehata F,Pater A

更新日期：2005-06-01 00:00:00

abstract：:Rosbin (Thieno [2, 3-c] piperidine-3-carboxamide-2-[(3-methoxy-naphtha-lene-2-carbonyl)-amino]-6-(benzyl)-, hydrochloride), a synthetic piperidinothieno derivative compound obtained from chemical genetics screenings, significantly suppresses the viability of non-small cell lung cancer A549 cells with an IC50 of 2.05 ±...

journal_title：Cell biology international

authors： Zhao T,Jin W,Pan H,Li H,Zhao Y,Feng Y

更新日期：2017-02-01 00:00:00

abstract：:Emergence of resistance to chemotherapy and radiotherapy is a major obstacle for the successful treatment of MM (multiple myeloma). Prednisone, vincristine and melphalan are commonly used chemotherapeutic agents for the treatment of MM. In the current study, we examined the presence of possible cross-resistance betwee...

journal_title：Cell biology international

authors： Mutlu P,Baran Y,Ural AU,Avcu F,Dirican B,Beyzadeoglu M,Gündüz U

更新日期：2011-07-01 00:00:00

abstract：:Human tissues are sophisticated ensembles of various distinct cell types encapsulated in the biomechanical cues of the extracellular matrix. It has been known matrix stiffness plays a pivot role in cellular events and tissue-scale biological processes. Thus, materials that can mimic mechanical environments of tissues ...

journal_title：Cell biology international

authors： Zhao H,Xu K,Zhu P,Wang C,Chi Q

更新日期：2019-02-01 00:00:00

abstract：:The aim of the present study was to investigate stress fibers and cortical actin reorganization in pubertal Sertoli cells in vitro after PMA treatment. Actin was studied by means of immunogold labeling, using the 'Progressive Lowering of Temperature' technique (PLT). Actin rearrangement was evaluated by a quantitative...

journal_title：Cell biology international

authors： Panagopoulou E,Kouloukoussa M,Kittas C,Marinos E

更新日期：2005-11-01 00:00:00