Differentiation of embryonic stem cells towards pancreatic progenitor cells and their transplantation into streptozotocin-induced diabetic mice.

abstract：:Cell-matrix and cell-cell interactions are important physiological determinants of cell growth, survival and transformation. Cell adhesion to the extra cellular matrix (ECM) via integrins also crucially influences the organization of the cytoskeleton. It triggers a cascade of intracellular biochemical events, which re...

journal_title：Cell biology international

authors： Rajeswari J,Pande G

更新日期：2002-01-01 00:00:00

abstract：:The aim of this study was to determine the polarization of macrophages in the tumor microenvironment, as well as the effect of soluble factors secreted from these polarized macrophages on etoposide-induced cancer cell apoptosis. We investigated the effect of soluble factors secreted from the supernatant of PC3 cells t...

journal_title：Cell biology international

authors： Malekghasemi S,Majidi J,Baradaran B,Aghebati-Maleki L

更新日期：2020-10-01 00:00:00

abstract：:The interaction of NO and O2- free radicals generated from PMA (phorbol myristate acetate)-stimulated PMN (polymorphonuclear leukocytes) was studied by a nitroxide spin trap, DMPO (5,5-dimethyl-1-pyrroline-1-oxide). It was found that addition of L-arginine to the system would significantly decrease the trapped O2- by ...

journal_title：Cell biology international

authors： Zhao BL,Wang JC,Hou JW,Xin WJ

更新日期：1996-05-01 00:00:00

abstract：:We investigated the effect of triptolide (TP) on spinal cord injury (SCI), and its underlying mechanism. Following the establishment of the SCI model using YFP H-line transgenic mice, TP was intraperitoneally injected at a dose of 0.2 mg/kg once daily for 7 days. Behavioral tests, Nissl staining, and hematoxylin-eosin...

journal_title：Cell biology international

authors： Zhu N,Ruan J,Yang X,Huang Y,Jiang Y,Wang Y,Cai D,Geng Y,Fang M

更新日期：2020-03-01 00:00:00

abstract：:To define the molecular structure of bovine lens epithelium and its anterior lens capsule, we investigated the composition of lens capsule basement membrane proteins. Immunofluorescence and immunogold techniques were used to demonstrate the presence of type I and type III collagen in the lens capsule and in primary ex...

journal_title：Cell biology international

authors： Sawhney RS

更新日期：2005-02-01 00:00:00

abstract：:A view is emerging that human amylin (HA) kills pancreatic islet beta-cells by apoptosis. This study strengthens this view by documenting time-dependent morphological and ultrastructural changes in 10 microm HA-treated cultured RINm5F islet beta-cells. Membrane blebbing and microvilli loss were the earliest detectable...

journal_title：Cell biology international

authors： Saafi EL,Konarkowska B,Zhang S,Kistler J,Cooper GJ

更新日期：2001-01-01 00:00:00

abstract：:The efficacies of chemotherapeutic agents are often limited by side effects and acquired drug resistance. We have investigated whether the differential expression pattern of 14-3-3σ affects cisplatin response in non-small cell lung cancer cell lines. Two pairs of parental/cisplatin resistant cell lines (A549/CRA549 an...

journal_title：Cell biology international

authors： Cetintas VB,Tetik A,Cok G,Kucukaslan AS,Kosova B,Gunduz C,Veral A,Eroglu Z

更新日期：2013-01-01 00:00:00

abstract：:DNA is constantly being damaged, either by endogenous or exogenous genotoxins. In that regard, DNA repair activities are essential for maintaining genomic stability and to life itself. Mutations in genes encoding DNA repair proteins cause severe human syndromes, but DNA repair defects have also been linked to several ...

journal_title：Cell biology international

authors： Prates Mori M,de Souza-Pinto NC

更新日期：2018-06-01 00:00:00

abstract：:Epilepsy was characterized by the occurrence of spontaneous recurrent epileptiform discharges (SREDs) in neurons. Previous studies suggested that microRNA (miR)-139-5p and the Notch pathway were implicated in Epilepsy; however, their interaction remained vague. Rat primary hippocampal neurons were isolated and identif...

journal_title：Cell biology international

authors： Zhao C,Yang F,Wei X,Zhang J

更新日期：2020-11-28 00:00:00

abstract：:Hepatic oval cells are likely to be activated during advanced stage of liver fibrosis to reconstruct damaged hepatic tissue. However, their scarcity, difficulties in isolation, and in vitro expansion hampered their transplantation in fibrotic liver. This study was aimed to investigate the repair potential of in vitro ...

journal_title：Cell biology international

authors： Awan SJ,Baig MT,Yaqub F,Tayyeb A,Ali G

更新日期：2017-01-01 00:00:00

abstract：:Endothelial progenitor cells (EPCs) are precursor cells of vascular endothelial cells, which are widely involved in the pathological process of cardiovascular diseases. EPCs apoptosis could accelerate the process of cardiovascular diseases. 14-3-3-η protein has been proved to be a potent antiapoptosis molecule. Howeve...

journal_title：Cell biology international

authors： Li Y,Sun X,Zhang X,Zhou H,Wang D,Xia Y,Li X

更新日期：2020-12-15 00:00:00

abstract：:It has been proposed that cyclical gene expression occurs at a large number of different times during the cell cycle. The existence of a large number of cycle-specific variations in mRNA and protein during the eukaryotic cell cycle raises the problem of how cell-cycle variations are regulated. This is the "infinite re...

journal_title：Cell biology international

authors： Cooper S,Shedden K,Vu-Phan D

更新日期：2009-01-01 00:00:00

abstract：:Breast cancer is one of the most common cancers in the female population worldwide, and its development is thought to be associated with genetic mutations that lead to uncontrolled and accelerated growth of breast cells. This abnormal behavior requires extra energy, and indeed, tumor cells display a rewired energy met...

journal_title：Cell biology international

authors： Lacerda-Abreu MA,Russo-Abrahão T,Leite Tenório Aguiar R,Monteiro RQ,Rumjanek FD,Meyer-Fernandes JR

更新日期：2020-11-03 00:00:00

abstract：:The purpose of this study was three fold: (1) to reveal the implications of Wnt5A for cytokine and chemokine production by human ovarian cancer cell line SKOV-3 cells, (2) to determine the influence of Wnt5A on chemotactic SKOV-3 cell migration, and (3) to assess the effect of inflammatory mediators on Wnt5A expressio...

journal_title：Cell biology international

authors： Arabzadeh S,Hossein G,Zarnani AH

更新日期：2016-02-01 00:00:00

abstract：:Cattle plays an important role in providing essential nutrients through meat production. Thus, we focused on epigenetic factors associated with meat yield. To investigate circulating miRNAs that are involved with meat yield and connect biofluids and longissimus dorsi (LD) muscle in Korean cattle, we performed analyses...

journal_title：Cell biology international

authors： Lee S,Park SJ,Cheong JK,Ko JY,Bong J,Baik M

更新日期：2017-07-01 00:00:00

abstract：:We previously reported that mechanical vibration-induced proinflammatory cytokines, interleukin-6 (IL-6) and IL-8, expression in human periodontal ligament (hPDL) cells, however, the underlying mechanism remained unclear. Mechanical stimuli are able to activate cellular responses by inducing the activation of several ...

journal_title：Cell biology international

authors： Phusuntornsakul P,Jitpukdeebodintra S,Pavasant P,Leethanakul C

更新日期：2020-02-01 00:00:00

abstract：:The spreading behaviour of dissociated hypoblast cells on and besides a band of aligned fibrils associated with the basal lamina of the epiblast was investigated by the use of scanning electron microscopy. A horse-shaped band of aligned fibrils, first demonstrated by Wakely and England (1979), is present during the ga...

journal_title：Cell biology international

authors： Andries L,Harrisson F,Vakaet L

更新日期：1994-07-01 00:00:00

abstract：:microRNAs (miRNAs), through negatively regulating their target genes, influence the development and progression of many cancers. Previously, we found miR-483 was overexpressed in esophageal squamous cell carcinoma (ESCC) tissues, and its overexpression was negatively correlated with the prognosis and positively correl...

journal_title：Cell biology international

authors： Ma J,Hong L,Xu G,Hao J,Wang R,Guo H,Liu J,Zhang Y,Nie Y,Fan D

更新日期：2016-04-01 00:00:00

abstract：:In the adult brain, neural stem cells from the subgranular zone (SGZ) of the hippocampus and the subventricular zone (SVZ) of the cortex progress through the following five developmental stages: radial glia-like cells, neural progenitor cells, neuroblasts, immature neurons, and mature neurons. These developmental stag...

journal_title：Cell biology international

authors： Jia S,Mou C,Ma Y,Han R,Li X

更新日期：2016-04-01 00:00:00

abstract：:Using flow cytometry and confocal microscopy, the presence of endorphin, serotonin and chorionic gonadotropin (hCG) was demonstrated in rat white blood cells and peritoneal mast cells. After a single neonatal treatment with beta-endorphin (hormonal imprinting), the mast cells of female rats reaching adulthood containe...

journal_title：Cell biology international

authors： Csaba G,Kovács P,Pállinger E

更新日期：2003-01-01 00:00:00

abstract：:Pig endothelial cells are the first cells to interact with human immune components after organ xenotransplantation, which is a procedure currently considered to be the best treatment option for end-stage organ failure. It is, therefore, essential to study the mechanisms of molecular interaction between pig endothelial...

journal_title：Cell biology international

authors： Kim D,Kim JY,Koh HS,Lee JP,Kim YT,Kang HJ,Hwang WS,Kim YB,Lee JS,Ahn C

更新日期：2005-08-01 00:00:00

abstract：:Adult peripheral blood-derived cells are able to differentiate into a variety of cell types, including nerve cells, liver-like cells and epithelial cells. However, their differentiation into retina-like cells is controversial. In the present study, transdifferentiation potential of human adult peripheral blood mononuc...

journal_title：Cell biology international

authors： Liu Q,Guan L,Huang B,Li W,Su Q,Yu M,Xu X,Luo T,Lin S,Sun X,Chen M,Chen X

更新日期：2011-06-01 00:00:00

abstract：:The Kv2.1 potassium channel is a principal component of the delayed rectifier I(K) current in the pyramidal neurons of cortex and hippocampus. We used whole-cell patch-clamp recording techniques to systemically compare the electrophysiological properties between the native neuronal I(K) current of cultured rat hippoca...

journal_title：Cell biology international

authors： Liu M,Gong B,Qi Z

更新日期：2008-12-01 00:00:00

abstract：:Although clinical data suggest remarkable promise for targeting programmed cell death protein-1 (PD-1) and ligand (PD-L1) signaling in non-small-cell lung cancer (NSCLC), it is still largely undetermined which subtype of patients will be responsive to checkpoint blockade. In the present study, we explored whether PD-L...

journal_title：Cell biology international

authors： Pan LN,Ma YF,Li Z,Hu JA,Xu ZH

更新日期：2020-12-15 00:00:00

abstract：:Small heat shock proteins (shsps) are molecular chaperones that are inducible by environmental stress. In this study, immunocytochemical analysis and laser scanning confocal microscopy revealed that the shsp family, hsp30, was localized primarily in the cytoplasm of Xenopus A6 kidney epithelial cells after heat shock ...

journal_title：Cell biology international

authors： Gellalchew M,Heikkila JJ

更新日期：2005-03-01 00:00:00

abstract：:Most hepatomas have a defect in prothrombin carboxylation, and can secrete under-carboxylated prothrombin or des-gamma-carboxy-prothrombin (DCP), the function of which is unknown. We considered that the prothrombin-DCP axis might also be involved in growth control. Hepatocytes and hepatoma cells were treated with prot...

journal_title：Cell biology international

authors： Carr BI,Kar S,Wang M,Wang Z

更新日期：2007-09-01 00:00:00

abstract：:We have previously reported that the T cell line Jurkat registers the exposure of a sinusoidal extremely low frequency magnetic field at the level of the plasma membrane, resulting in activation of the tyrosine kinase p56(lck), increase in inositol-3-phosphate levels and increase in intracellular calcium concentration...

journal_title：Cell biology international

authors： Still M,Lindström E,Ekstrand AJ,Mild KH,Mattsson MO,Lundgren E

更新日期：2002-01-01 00:00:00

abstract：:In this study, we determined whether multilineage-differentiating stress-enduring (Muse) cells exist in rat bone marrow and elucidated their effects on protection against the injury of intestinal epithelial cells associated with inflammation. Rat Muse cells were separated from bone marrow mesenchymal stem cells (BMMSC...

journal_title：Cell biology international

authors： Sun D,Yang L,Cao H,Shen ZY,Song HL

更新日期：2020-02-01 00:00:00

abstract：:The single-minded 2 gene (Sim2) plays a crucial role in the mental retardation of Down Syndrome (DS). To explore how Sim2 influences spatial memory, a DNA plasmid-encoding mouse Sim2 (mSim2) wrapped with liposome was bilaterally injected into the hippocampus of rats. The effect of overexpressing mSim2 on spatial learn...

journal_title：Cell biology international

authors： Meng X,Peng B,Shi J,Zheng Y,Chen H,Zhang J,Li L,Zhang C

更新日期：2006-10-01 00:00:00

abstract：:The function of the gene gilgamesh (89B9-12) encoding a casein kinase in Drosophila spermatogenesis was studied. The chimeric Gilgamesh-GFP protein in spermatocytes is cortically located. In the polar and apolar spermatocytes, it concentrates at the terminal ends of the fusome, the organelle that passes through the sy...

journal_title：Cell biology international

authors： Nerusheva OO,Dorogova NV,Gubanova NV,Yudina OS,Omelyanchuk LV

更新日期：2009-05-01 00:00:00