Effects of overexpression of Sim2 on spatial memory and expression of synapsin I in rat hippocampus.

abstract：:Ro52/SSA is an autoantigen that presents in patients with SS (Sjögren's syndrome) and SLE (systemic lupus erythematosus). It increases cell death and redistributes itself to apoptotic blebs, but its pro-apoptotic function has not been completely identified. Overexpression of Ro52/SSA promoted cell apoptosis induced by...

journal_title：Cell biology international

authors： Zhang J,Fang L,Zhu X,Qiao Y,Yu M,Wang L,Chen Y,Yin W,Hua ZC

更新日期：2012-05-01 00:00:00

abstract：:Primary cilium development along with other components of the centrosome in mammalian cells was analysed ultrastructurally and by immunofluorescent staining with anti-acetylated tubulin antibodies. We categorized two types of primary cilia, nascent cilia that are about 1microm long located inside the cytoplasm, and tr...

journal_title：Cell biology international

authors： Alieva IB,Vorobjev IA

更新日期：2004-01-01 00:00:00

abstract：:Human myometrial smooth muscle cells (SMCs) were used to evaluate the proliferative activity of lysophosphatidic acid (LPA). This study specifically focuses on the role of Ca(2+)/calmodulin-dependent protein (CaM) kinase and epidermal growth factor (EGF) receptor tyrosine kinase. Myometrial SMCs were cultured from bio...

journal_title：Cell biology international

authors： Nilsson UK,Svensson SP

更新日期：2003-01-01 00:00:00

abstract：:Epilepsy was characterized by the occurrence of spontaneous recurrent epileptiform discharges (SREDs) in neurons. Previous studies suggested that microRNA (miR)-139-5p and the Notch pathway were implicated in Epilepsy; however, their interaction remained vague. Rat primary hippocampal neurons were isolated and identif...

journal_title：Cell biology international

authors： Zhao C,Yang F,Wei X,Zhang J

更新日期：2020-11-28 00:00:00

abstract：:Recently, we reported that human PDB (placental decidua basalis) is an excellent source of MSCs (mesenchymal stem cells), meanwhile, PDB-MSCs could survive under hypoxia and serum deprivation. Herein, we investigated the proliferation, clonogentic efficiency, phenotypes, metabolic activity and cytokines secretion of P...

journal_title：Cell biology international

authors： Huang YC,Yang ZM,Jiang NG,Chen XH,Li XQ,Tan MY,Zhou KP,Tang L,Xie HQ,Deng L

更新日期：2010-01-27 00:00:00

abstract：:The interaction of NO and O2- free radicals generated from PMA (phorbol myristate acetate)-stimulated PMN (polymorphonuclear leukocytes) was studied by a nitroxide spin trap, DMPO (5,5-dimethyl-1-pyrroline-1-oxide). It was found that addition of L-arginine to the system would significantly decrease the trapped O2- by ...

journal_title：Cell biology international

authors： Zhao BL,Wang JC,Hou JW,Xin WJ

更新日期：1996-05-01 00:00:00

abstract：:Protein composition and functional activity of various polysome subpopulations isolated from Vicia faba L. leaves and Triticum aestivum L. and Hordeum vulgare L. seedlings were studied. Membrane- and cytoskeleton-bound polysomes were more active in the wheat germ cell-free translational system than free polysomes. Sev...

journal_title：Cell biology international

authors： Klyachko N,Aksenova L,Dunaeva M,Kulikova A

更新日期：2000-01-01 00:00:00

abstract：:Hyperglycemia is one of the most important pathogenesis of diabetic osteopathy. Several lines of studies indicate Runx2 plays a critical role in the process of osteogenic differentiation. However, little studies have analyzed the effect of Runx2 on osteoblast differentiation of rat bone mesenchymal stem cells (rBMSCs)...

journal_title：Cell biology international

authors： Chen Y,Hu Y,Yang L,Zhou J,Tang Y,Zheng L,Qin P

更新日期：2017-08-01 00:00:00

abstract：:BPD (bronchopulmonary dysplasia) is predominantly characterized by persistent abnormalities in lung structure and arrested lung development, but therapy can be palliative. While promising, the use of BMSC (bone marrow-derived mesenchymal stem cell) in the treatment of lung diseases remains controversial. We have asses...

journal_title：Cell biology international

authors： Zhang X,Wang H,Shi Y,Peng W,Zhang S,Zhang W,Xu J,Mei Y,Feng Z

更新日期：2012-06-01 00:00:00

abstract：:TZDs (thiazolidinediones) are prescribed as anti-Type II diabetes drugs, but little is known regarding whether TZDs regulate the expression of sPLA2 (secretory phospholipase A2) in macrophages. We have investigated the effects of pioglitazone on LPS (lipopolysaccharide)-induced production of TNF-alpha (tumour necrosis...

journal_title：Cell biology international

authors： Ao C,Huo Y,Qi L,Xiong Z,Xue L,Qi Y

更新日期：2010-07-01 00:00:00

abstract：:The aim of the present study was to determine the effects of ARHI (aplasia Ras homologue member I; also known as DIRAS3), a member of the Ras superfamily, on HCC (hepatocellular carcinoma) cells and to define the molecular pathways involved. Stable transfection of ARHI into the HCC cell line Hep3B that lacks expressio...

journal_title：Cell biology international

authors： Pei XH,Yang Z,Liu HX,Qiao SS

更新日期：2011-10-01 00:00:00

abstract：:In the past decades increasing lines of evidence have demonstrated that adipose tissue, as an endocrine organ plays a central role in metabolic homeostasis and its related maladies. CCAAT/enhancer-binding protein (C/EBP) family members and the nuclear receptor peroxisome proliferator-activated receptor gamma (PPARγ) w...

journal_title：Cell biology international

authors： Zhao XY,Chen XY,Zhang ZJ,Kang Y,Liao WM,Yu WH,Xiang AP

更新日期：2015-04-01 00:00:00

abstract：:Accurate relative gene expression analysis by reverse transcription-quantitative polymerase chain reaction relies on the usage of suitable reference genes for data normalization. The RNA content of small extracellular vesicles including exosomes is growingly considered as cancer biomarkers. So, reliable relative quant...

journal_title：Cell biology international

authors： Gorji-Bahri G,Moradtabrizi N,Vakhshiteh F,Hashemi A

更新日期：2021-01-27 00:00:00

abstract：:The authors examined the growth response of cardinal ligamental fibroblasts derived from patients with prolapsus uteri (HPLiF) and compared it with the response of those from control subjects (HCLiF). The growth rate during the logarithmic growth phase was not different between HPLiF and HCLiF, while the cell density ...

journal_title：Cell biology international

authors： Yamamoto M,Aoyagi M,Akazawa K,Tajima S,Yamamoto K

更新日期：1998-01-01 00:00:00

abstract：:Glutamyl aminopeptidase (GluAP, EC 3.4.11.7, ENPEP) is a 130-kDa homodimeric zinc metallopeptidase which specifically cleaves the N-terminal glutamate or aspartate residue of peptidic substrates such as cholecystokinin-8 or angiotensin (Ang) II, in vitro. We used a DNA microarray hybridization (Genechip Rat Expression...

journal_title：Cell biology international

authors： Wu Y,Xiao J,Wu L,Tian W,Liu L

更新日期：2008-07-01 00:00:00

abstract：:The influence of maternal nicotine exposure during pregnancy and lactation on the Type II cells of lung tissue of one day old neonatal rat pups was investigated. The results clearly show that maternal nicotine exposure resulted in an increase in the type II cell count in the lungs of the offspring. In addition the lam...

journal_title：Cell biology international

authors： Maritz GS,Thomas RA

更新日期：1995-04-01 00:00:00

abstract：:The unicellular Tetrahymena has receptors for hormones of higher vertebrates, produces these hormones, and their signal pathways are similar. The first encounter with a hormone in higher dose provokes the phenomenon of hormonal imprinting, by which the reaction of the cell is quantitatively modified. This modification...

journal_title：Cell biology international

authors： Kőhidai L,Lajkó E,Pállinger E,Csaba G

更新日期：2012-10-01 00:00:00

abstract：:We have monitored the effects of KLKL(5)KLK (KLK), a derivative of a natural cationic antimicrobial peptide (CAP) on isolated membrane vesicles, and investigated the partition of the peptide within these structures. KLK readily interacted with fluorescent dyes entrapped in the vesicles without apparent pore formation....

journal_title：Cell biology international

authors： Aichinger MC,Ortbauer M,Reipert S,Zauner W,Bogner P,Froschauer E,Nowikovsky K,Lingnau K,von Gabain A,Schweyen R,Henics T

更新日期：2008-11-01 00:00:00

abstract：:Tripartite motif-containing 22 (TRIM22) is reported to participate in numerous cellular activities. Recent studies confirm that TRIM22 is a target gene for P53, and inhibits clonogenic growth of leukemic U-937 cells. The current study aims to discover the effect of TRIM22 in progression of human chronic myeloid leukem...

journal_title：Cell biology international

authors： Li L,Qi Y,Ma X,Xiong G,Wang L,Bao C

更新日期：2018-09-01 00:00:00

abstract：:CO25 cells, a mouse myoblast line, contain multiple centrioles and primary cilia. A most unusual feature has been the finding of large numbers of separate structures in single cells-up to a maximum of nine centrioles, six primary cilia, and 12 of both organelles together. Aberrant multipolar spindles were occasionally...

journal_title：Cell biology international

authors： Zeytinoglu M,Ritter J,Wheatley DN,Warn RM

更新日期：1996-12-01 00:00:00

abstract：:Metallothioneins (MTs) are thought to participate in a wide variety of physiological roles, but the mechanisms involved are still unclear. The study was designed to examine the possible factors related to these mechanisms. Methods, including transfection, MTT assay and flow cytometry, were used to investigate the effe...

journal_title：Cell biology international

authors： Li J,Liu Y,Ru B

更新日期：2005-10-01 00:00:00

abstract：:Acylase 1 was investigated at the cellular level in the rat small intestine along the enterocyte-differentiation axis. As confirmed by microscopic analysis, villus tip cells and crypt cells of rat jejunal mucosa were successfully separated using the Weiser method. The proliferating undifferentiated crypt cells showed ...

journal_title：Cell biology international

authors： Cigna N,Nicoletti C,Durand A,Chaix JC,Giardina T,Perrier J

更新日期：2007-09-01 00:00:00

abstract：:The objective of this study was to determine if adenosine alters growth of mammary epithelium. Mouse mammary epithelial cells (NMuMG) were cultured in DMEM supplemented with 10% fetal calf serum. After serum starvation for 24 h, EGF (0-100 ng/ml) and/or adenosine (0-100 microM) was added. Adenosine at concentrations o...

journal_title：Cell biology international

authors： Yuh IS,Jang BB,Hong BJ

更新日期：1998-01-01 00:00:00

abstract：:Inner ear cells, including hair cells, spiral ganglion cells, stria vascularis cells and supporting cells on the basilar membrane, play a major role in transducing hearing signals and regulating inner ear homoeostasis. However, their functions are often damaged by antibiotic-induced ototoxicity. Apoptosis is probably ...

journal_title：Cell biology international

authors： Yu L,Tang H,Jiang XH,Tsang LL,Chung YW,Chan HC

更新日期：2010-12-01 00:00:00

abstract：:In the adult brain, neural stem cells from the subgranular zone (SGZ) of the hippocampus and the subventricular zone (SVZ) of the cortex progress through the following five developmental stages: radial glia-like cells, neural progenitor cells, neuroblasts, immature neurons, and mature neurons. These developmental stag...

journal_title：Cell biology international

authors： Jia S,Mou C,Ma Y,Han R,Li X

更新日期：2016-04-01 00:00:00

abstract：:We have studied the effect of enhanced expression of epithelial Na(+)channels (ENaC) on the ATP-induced Cl(-)secretion in the mouse epithelium using short-circuit current (I(SC)) and RT-PCR techniques. The amiloride sensitivity of basal current (I(b)) across the cultured endometrial epithelia was found to vary with th...

journal_title：Cell biology international

authors： Wang XF,Tsang LL,So SC,Chan HC

更新日期：2001-01-01 00:00:00

abstract：:Heat shock proteins (HSPs) are molecular chaperones involved in protein folding, assembly and transport, and which play critical roles in the regulation of cell growth, survival and differentiation. We set out to test the hypothesis that HSP27 protein is expressed in the human testes and its expression varies with the...

journal_title：Cell biology international

authors： Adly MA,Assaf HA,Hussein MR

更新日期：2008-10-01 00:00:00

abstract：:Gelatinase activity and inhibitory activity against collagenase were measured in serum-free medium conditioned by murine colonic carcinoma cells with different spontaneous metastatic potentials to the lung. The medium conditioned with poorly metastatic NM11 cells gave higher inhibitory activity than that conditioned w...

journal_title：Cell biology international

authors： Kishi J,Tanaka R,Koiwai O,Yamagata S,Numata Y,Hayakawa T,Shimizu S

更新日期：1994-03-01 00:00:00

abstract：:Reactive oxygen species (ROS) act as signaling molecules to regulate various cell functions. Numerous studies have demonstrated ROS to be essential for the differentiation of adipocytes. Peroxiredoxins (Prxs) are a ubiquitous family of antioxidant enzymes in mammalian cells. Prx2 is present in the cytoplasm and cell m...

journal_title：Cell biology international

authors： Kim MH,Kim JY,Kim JH,Lee HS,Huh JW,Lee DS

更新日期：2020-10-01 00:00:00

abstract：:Peroxynitrite was found to induce the release of K+ via the Na+/Cl- cotransport system, as do other oxidants. Since peroxynitrite is formed in vivo, its presence could contribute to a pathological dehydration of red blood cells. ...

journal_title：Cell biology international

authors： Grzelak A,Mazur J,Bartosz G

更新日期：2001-01-01 00:00:00