Triptolide improves spinal cord injury by promoting autophagy and inhibiting apoptosis.

abstract：:Spermatogonia and sperm-like cells can be derived in vitro via the addition of RA (retinoic acid) to pluripotent ES and EG cells. At present, however, these cells have not been derived from unipotent cells. Here, we have generated premeiotic Stra8-positive cells from C2C12 myoblasts following treatment with 10 μM all-...

journal_title：Cell biology international

authors： Jia W,Cheng D,Chen S,Lei L,Wang H

更新日期：2011-04-01 00:00:00

abstract：:MiR-195-5p has been shown to play an essential role in human cancer progression. Nevertheless, the biological role of miR-195-5p in osteosarcoma development remains unclear. In this study, real-time PCR was performed to examine the miR-195-5p expression in human osteosarcoma cell lines. CCK-8 assay and Transwell assay...

journal_title：Cell biology international

authors： Qu Q,Chu X,Wang P

更新日期：2017-03-01 00:00:00

abstract：:Transplanted tumours could modify the intensity and temporal distribution of the cellular proliferation in normal cell populations, and partial hepatectomy alters the serum concentrations of substances involved in cellular proliferation, leading to the compensatory liver hyperplasia. The following experiments were des...

journal_title：Cell biology international

authors： García MN,Andrini LB,Inda AM,Ronderos JR,Hijano JC,Errecalde AL

更新日期：2010-02-05 00:00:00

abstract：:Cutaneous squamous cell carcinoma (SCC) is a malignant tumour of keratinising epidermal cells. This type of skin cancer is the second leading cause of death after melanoma, and it is the second most common type of non-melanoma skin cancer after basal cell carcinoma. The cellular and molecular events involved in the pr...

journal_title：Cell biology international

authors： Salehi Z,Mashayekhi F,Shahosseini F

更新日期：2007-11-01 00:00:00

abstract：:This study provides evidence that, in the soluble fraction from buffer-washed pea thylakoids, one form of soluble carbonic anhydrase (CA) is associated with rubisco in a stromal protein complex. On native-PAGE gels, it is present as a protein band with MW approximately 160 kDa. On SDS-PAGE gels, it is resolved as a si...

journal_title：Cell biology international

authors： Lazova GN,Stemler AJ

更新日期：2008-06-01 00:00:00

abstract：:Life cannot be simply defined in biochemical terms but it is associated with autodynamic behaviour. This fact implies that all aspects of cell biology should be viewed in terms of the resultant temporal features. Theoretical arguments indicate that the dynamic state can be explained only by the existence of periodicit...

journal_title：Cell biology international

authors： Gilbert D,Lloyd D

更新日期：2000-01-01 00:00:00

abstract：:Disconnected interacting protein 2 (DIP2) is a highly conserved protein family among invertebrates and vertebrates, but its function remains unclear. In this paper, we summarized the conservation of gene sequences and protein domains of DIP2 family members and predicted that they may have a similar functional role in ...

journal_title：Cell biology international

authors： Ma J,Chen L,He XX,Wang YJ,Yu HL,He ZX,Zhang LQ,Zheng YW,Zhu XJ

更新日期：2019-04-01 00:00:00

abstract：:Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) gains access to host cells by attaching to angiotensin-converting enzyme 2 (ACE2). Vitamin D (VitD) can upregulate ACE2 and has an antagonistic effect on Renin, which exerts a vasodilatation and anti-inflammatory effect against coronavirus disease (COVID-19)...

journal_title：Cell biology international

authors： Shojaeefar E,Malih N,Rezaei N

更新日期：2021-01-01 00:00:00

abstract：:While much evidence indicates a high degree of spatial organization in the nucleus, the underlying molecular structures that support it remain poorly characterized. By extracting with high concentrations of RNase A in a modification of the sequential extraction protocol of Penman, we have identified a novel intranucle...

journal_title：Cell biology international

authors： Padros MR,Giles DM,Suarez MD

更新日期：1997-06-01 00:00:00

abstract：:The exon 16-encoded juxtamembrane (JM) domain of human insulin receptor (hIR) harbors the NPEY motif which couples the insulin-activated hIR kinase to downstream signal transduction molecules. We sought to determine if signal transduction requires the entire exon 16-encoded 22-amino acid JM domain. Transfected CHO cel...

journal_title：Cell biology international

authors： Sattar AA,Berhanu C,Gebreselassie S,Berhanu P

更新日期：2007-08-01 00:00:00

abstract：:Mesenchymal stem cells (MSCs) are multipotent progenitor cells that represent a promising approach in the field of regenerative medicine; however, this potential diminishes with senescence. Pigment epithelium-derived factor (PEDF) gives some protection by reducing oxidative stress, which is known to accelerate cellula...

journal_title：Cell biology international

authors： Cao Y,Yang T,Gu C,Yi D

更新日期：2013-04-01 00:00:00

abstract：:Forms of the protozoan of the Hepatozoon genus are detected free in the circulation and also within some of the erythrocytes of infected snakes. In healthy snakes, DNA fragmentation and cell death usually affect a few circulating erythrocytes in agreement with the long life span expected for these cells. In the presen...

journal_title：Cell biology international

authors： Miyamoto M,Mello ML

更新日期：2007-05-01 00:00:00

abstract：:Ghrelin-O-acyltransferase (GOAT) is a membrane-bound enzyme that attaches eight-carbon octanoate to a serine residue in ghrelin and thereby acylates inactive ghrelin to produce active ghrelin. In this study, we investigated the function of GOAT in the intestinal mucosal barrier. The intestinal mucosal barrier prevents...

journal_title：Cell biology international

authors： Tian P,Lu X,Jin N,Shi J

更新日期：2020-08-01 00:00:00

abstract：:Chloride secretion in primary cultures of cells originating from the secretory coil of human sweat glands was investigated by electron probe X-ray microanalysis. The total intracellular Cl concentration was lowered by muscarinic agonists (carbachol and acetylcholine), as well as by the calcium ionophore A23187. The mu...

journal_title：Cell biology international

authors： Mörk AC,Hongpaisan J,Roomans GM

更新日期：1995-02-01 00:00:00

abstract：:Epilepsy was characterized by the occurrence of spontaneous recurrent epileptiform discharges (SREDs) in neurons. Previous studies suggested that microRNA (miR)-139-5p and the Notch pathway were implicated in Epilepsy; however, their interaction remained vague. Rat primary hippocampal neurons were isolated and identif...

journal_title：Cell biology international

authors： Zhao C,Yang F,Wei X,Zhang J

更新日期：2020-11-28 00:00:00

abstract：:Expression of the canine 180-kDa ribosome receptor p180 in yeast induces the synthesis of RER, and increases the mRNAs of secretory pathway proteins, and protein secretion. To assess whether p180 is a master regulator of cell secretion in mammalian cells, we stably expressed red fluorescent forms of the human p180 var...

journal_title：Cell biology international

authors： Bai JZ,Leung E,Holloway H,Krissansen GW

更新日期：2008-05-01 00:00:00

abstract：:In spite of certain clinical limitations, such as teratoma formation, the use of stem cells is considered as an appropriate source in cell therapy and tissue engineering. This study shows human endometrial stem cells (hEnSCs) has exceptional differentiation ability in hepatocyte formation. hEnSCs have high purificatio...

journal_title：Cell biology international

authors： Khademi F,Soleimani M,Verdi J,Tavangar SM,Sadroddiny E,Massumi M,Ai J

更新日期：2014-07-01 00:00:00

abstract：:Cell proliferation rates of diagnostic marrow aspirate cells of 21 children with Acute Lymphoblastic Leukaemia and 16 controls were compared using immunocytochemical labelling of PCNA and Ki-67 antigen as assessed by Confocal Laser Scanning Microscopy. The results showed an unexpected, highly significant degree of dis...

journal_title：Cell biology international

authors： Ball LM,Pope J,Howard CV,Eccles P,van Velzen D

更新日期：1994-09-01 00:00:00

abstract：:Stem/progenitor cells hold promise for alleviating/curing type 1 diabetes due to the capacity to differentiate into functional insulin-producing cells. The current study aims to assess the differentiation potential of human pancreatic IPCs (islet-derived progenitor cells). IPCs were derived from four human donors and ...

journal_title：Cell biology international

authors： Zhang Y,Ren Z,Zou C,Wang S,Luo B,Li F,Liu S,Zhang YA

更新日期：2011-05-01 00:00:00

abstract：:Human tissues are sophisticated ensembles of various distinct cell types encapsulated in the biomechanical cues of the extracellular matrix. It has been known matrix stiffness plays a pivot role in cellular events and tissue-scale biological processes. Thus, materials that can mimic mechanical environments of tissues ...

journal_title：Cell biology international

authors： Zhao H,Xu K,Zhu P,Wang C,Chi Q

更新日期：2019-02-01 00:00:00

abstract：:BPD (bronchopulmonary dysplasia) is predominantly characterized by persistent abnormalities in lung structure and arrested lung development, but therapy can be palliative. While promising, the use of BMSC (bone marrow-derived mesenchymal stem cell) in the treatment of lung diseases remains controversial. We have asses...

journal_title：Cell biology international

authors： Zhang X,Wang H,Shi Y,Peng W,Zhang S,Zhang W,Xu J,Mei Y,Feng Z

更新日期：2012-06-01 00:00:00

abstract：:To establish useful human normal cell lines, TERT (telomerase reverse transcriptase) cDNA was transfected into normal female lung fibroblast, TIG-1. After long-term-sub-cultivation of 74 individual clones selected for resistance to G418, we obtained 55 cultures with normal range of life span [75 PDL (population doubli...

journal_title：Cell biology international

authors： Kamada M,Kumazaki T,Matsuo T,Mitsui Y,Takahashi T

更新日期：2012-06-01 00:00:00

abstract：:Having the ability to control cell behaviour would be of great advantage in tissue engineering. One method of gaining control over cell adhesion, proliferation, guidance and differentiation is use of topography. Whilst it has be known for some time that cells can be guided by micro-topography, it is only recently beco...

journal_title：Cell biology international

authors： Dalby MJ,Riehle MO,Johnstone H,Affrossman S,Curtis AS

更新日期：2004-01-01 00:00:00

abstract：:Transcriptional regulation and binding interactions between soluble nucleoproteins and the hormone response elements (REs) of the rat haptoglobin (Hp) and alpha 2-macroglobulin (alpha 2MG) genes was examined in the livers of rats during the acute-phase reaction. Our results demonstrate that the elevation of the Hp and...

journal_title：Cell biology international

authors： Petrović M,Bogojević D,Grigorov I,Sevaljević L

更新日期：1995-12-01 00:00:00

abstract：:Annexin I is an abundant cytosolic protein in human neutrophils. Besides its intracellular location, annexin I is found as an extracellular protein and the pathway for secretion has been of interest since the protein lacks a signal sequence for secretion. It was recently shown that annexin I is stored in the secretory...

journal_title：Cell biology international

authors： Movitz C,Dahlgren C

更新日期：2001-01-01 00:00:00

abstract：:Inner ear cells, including hair cells, spiral ganglion cells, stria vascularis cells and supporting cells on the basilar membrane, play a major role in transducing hearing signals and regulating inner ear homoeostasis. However, their functions are often damaged by antibiotic-induced ototoxicity. Apoptosis is probably ...

journal_title：Cell biology international

authors： Yu L,Tang H,Jiang XH,Tsang LL,Chung YW,Chan HC

更新日期：2010-12-01 00:00:00

abstract：:Mouse trisomy 16 (Ts16) appears to provide an animal model of Down's syndrome in that a portion of mouse chromosome 16 is syntenic with part of human chromosome 21. Trisomy 21 in human beings leads to the mental retardation of Down's syndrome and in middle age, to some presenile anatomic and clinical features of Alzhe...

journal_title：Cell biology international

authors： Lane NJ,Balbo A,Rapoport SI

更新日期：1996-10-01 00:00:00

abstract：:Insulin resistance (IR) is a hallmark of type 2 diabetes mellitus (T2DM). This study aimed to explore the effects of rapamycin, a specific inhibitor of kinase mammalian target of rapamycin (mTOR), on IR in T2DM rats, and to validate whether the underlying mechanism was associated with autophagy. In this study, the mod...

journal_title：Cell biology international

authors： Zhou W,Ye S

更新日期：2018-09-01 00:00:00

abstract：:Tissue engineering of bone has been increasingly used in the bone defect repair. To generate osteoblasts is a major approach, and here we have examined ways of improving the efficiency of producing osteoblasts. Adipose stem cells (ADSC) were prepared from rat mesentery tissue, and transfected with Cbfa1 gene vector or...

journal_title：Cell biology international

authors： Wang L,Wang H,Xu X,Wang D,Liu H

更新日期：2013-11-01 00:00:00

abstract：:Continuous variation in the direction of the gravity vector leads to various cellular responses including modulation of gene expression. Complementary DNA (cDNA) array analyses are available to observe the variation of gene expression under different conditions. In this study, expression levels of 588 representative g...

journal_title：Cell biology international

authors： Arase Y,Nomura J,Sugaya S,Sugita K,Kita K,Suzuki N

更新日期：2002-01-01 00:00:00