Functional prediction and characterization of Dip2 gene in mice.

abstract：:Silicon dioxide induces acute injury and chronic pulmonary fibrosis. International Agency for Research on Cancer (IARC) listed it as a human carcinogen in 1996. However, the molecular mechanisms to induce cancer are not understood yet. The content of poly (ADP-ribose) polymerases (PARP) mRNA and protein in Hela cells ...

journal_title：Cell biology international

authors： Gao A,Song S,Wang D,Peng W,Tian L

更新日期：2009-07-01 00:00:00

abstract：:Our aim has been to elucidate the possible mechanism of CJX1, an amlodipine derivative, in the modulation of P-gp function by determining its effect on P-gp ATPase activity. Basal P-gp ATPase activity was increased by CJX1 with half-maximal activity concentration (Km) of 8.6+/-1.4 microM. Kinetic analysis indicated a ...

journal_title：Cell biology international

authors： Ji BS,He L

更新日期：2009-10-01 00:00:00

abstract：:Most hepatomas have a defect in prothrombin carboxylation, and can secrete under-carboxylated prothrombin or des-gamma-carboxy-prothrombin (DCP), the function of which is unknown. We considered that the prothrombin-DCP axis might also be involved in growth control. Hepatocytes and hepatoma cells were treated with prot...

journal_title：Cell biology international

authors： Carr BI,Kar S,Wang M,Wang Z

更新日期：2007-09-01 00:00:00

abstract：:In 3D cultured cell systems, the cells form 3D spheroids that mimic cancer cell spheroids in vivo. Cancer cells form cell spheroids as they grow. The in vivo spheroids do not contain a vascular network; therefore, oxygen and nutrition supplies are insufficient. Specifically, the cells in the core region of the cluster...

journal_title：Cell biology international

authors： Terashima J,Sampei S,Iidzuka M,Ohsakama A,Tachikawa C,Satoh J,Kudo K,Habano W,Ozawa S

更新日期：2016-11-01 00:00:00

abstract：:Stem cell biology has gained remarkable interest in recent years, driven by the hope of finding cures for numerous diseases including skin wound healing through transplantation medicine. Initially upon transplantation, these cells home to and differentiate within the injured tissue into specialised cells. Contrariwise...

journal_title：Cell biology international

authors： Jayaraman P,Nathan P,Vasanthan P,Musa S,Govindasamy V

更新日期：2013-10-01 00:00:00

abstract：:The effects of cadmium Cd (II) ions on the physiology and biological activity of Trametes versicolor, a strain belonging to white-rotting Basidiomycetes, were examined. Cd (II) ions were added to 10-day-old cultures grown on a liquid medium, or at the time of inoculation. Our experiments showed that T. versicolor is a...

journal_title：Cell biology international

authors： Jarosz-Wilkolazka A,Malarczyk E,Pirszel J,Skowroński T,Leonowicz A

更新日期：2002-01-01 00:00:00

abstract：:The low density lipoprotein receptor-related protein (alpha(2)MR/LRP) is a cell surface receptor which is present on most cells and tissues. We show that the 85 kDa subunit, containing the transmembrane region and cytoplasmic domain is phosphorylated in vivo. Comparison of the phosphorylation of the low density lipopr...

journal_title：Cell biology international

authors： Djordjevic JT,Waterkeyn JG,Hennessy KL,Stanley KK

更新日期：2000-01-01 00:00:00

abstract：:Hypoxia-inducible factor-1α (HIF-1α) and hepatocyte growth factor (HGF) play important roles in postnatal neovascularization. However, the interaction of these two pathways is not fully understood. The present study utilized CoCl(2) treated-endothelial progenitor cells (EPCs) (EPCs exposure to CoCl(2) are under mimic ...

journal_title：Cell biology international

authors： Yu F,Lin Y,Zhan T,Chen L,Guo S

更新日期：2015-03-01 00:00:00

abstract：:Human umbilical CD34(+) immature haematopoietic cells were rapidly and efficiently obtained from light density MNC (mononuclear cells) by MACS (magnetic cell sorting). An ex vivo expanded population of CD34(+) was cultured in serum-free medium supplemented with cytokines FL (flt3 ligand), SCF (stem cell factor) and TP...

journal_title：Cell biology international

authors： Maghdooni Bagheri P,De Ley M

更新日期：2011-01-01 00:00:00

abstract：:ZO-1 is a peripheral protein that plays a central role in the macromolecular assembly of tight junctions by interacting with integral proteins (occludin, claudins, JAMs) of the membrane of adjoining cells, with the actin cytoskeleton, and with nuclear factors. Human ZO-1 is expressed in all epithelia and some speciali...

journal_title：Cell biology international

authors： Ciana A,Meier K,Daum N,Gerbes S,Veith M,Lehr CM,Minetti G

更新日期：2010-05-07 00:00:00

abstract：:As part of a programme of comparative measurements of Pd (diffusional water permeability) the RBCs (red blood cells) from dingo (Canis familiaris dingo) and greyhound dog (Canis familiaris) were studied. The morphologies of the dingo and greyhound RBCs [examined by light and SEM (scanning electron microscopy)] were fo...

journal_title：Cell biology international

authors： Benga G,Chapman BE,Matei H,Cox GC,Romeo T,Mironescu E,Kuchel PW

更新日期：2010-03-08 00:00:00

abstract：:Adult peripheral blood-derived cells are able to differentiate into a variety of cell types, including nerve cells, liver-like cells and epithelial cells. However, their differentiation into retina-like cells is controversial. In the present study, transdifferentiation potential of human adult peripheral blood mononuc...

journal_title：Cell biology international

authors： Liu Q,Guan L,Huang B,Li W,Su Q,Yu M,Xu X,Luo T,Lin S,Sun X,Chen M,Chen X

更新日期：2011-06-01 00:00:00

abstract：:Key to mitochondrial activities is the maintenance of mitochondrial morphology, specifically cristae structures formed by the invagination of the inner membrane that are enriched in proteins of the electron transport chain. In Saccharomyces cerevisiae , these cristae folds are a result of the membrane fusion activitie...

journal_title：Cell biology international

authors： Huddleston ME,Xiao N,Both AP,Gordon DM

更新日期：2019-08-23 00:00:00

abstract：:Small heat shock proteins (shsps) are molecular chaperones that are inducible by environmental stress. In this study, immunocytochemical analysis and laser scanning confocal microscopy revealed that the shsp family, hsp30, was localized primarily in the cytoplasm of Xenopus A6 kidney epithelial cells after heat shock ...

journal_title：Cell biology international

authors： Gellalchew M,Heikkila JJ

更新日期：2005-03-01 00:00:00

abstract：:To establish useful human normal cell lines, TERT (telomerase reverse transcriptase) cDNA was transfected into normal female lung fibroblast, TIG-1. After long-term-sub-cultivation of 74 individual clones selected for resistance to G418, we obtained 55 cultures with normal range of life span [75 PDL (population doubli...

journal_title：Cell biology international

authors： Kamada M,Kumazaki T,Matsuo T,Mitsui Y,Takahashi T

更新日期：2012-06-01 00:00:00

abstract：:Lysosomal permeability to potassium ions is an important property of the organelle. Influence of the membrane physical state on the potassium ion permeability of isolated lysosomes was assessed by measuring the membrane potential with bis(3-propyl-5-oxoisoxazol-4-yl)pentamethine oxonol and monitoring the lysosomal pro...

journal_title：Cell biology international

authors： Wang J,Zhang GJ

更新日期：2005-06-01 00:00:00

abstract：:Reactive oxygen species (ROS) act as signaling molecules to regulate various cell functions. Numerous studies have demonstrated ROS to be essential for the differentiation of adipocytes. Peroxiredoxins (Prxs) are a ubiquitous family of antioxidant enzymes in mammalian cells. Prx2 is present in the cytoplasm and cell m...

journal_title：Cell biology international

authors： Kim MH,Kim JY,Kim JH,Lee HS,Huh JW,Lee DS

更新日期：2020-10-01 00:00:00

abstract：:Neuroinflammation is closely related with the pathogenesis and progress of neurodegenerative diseases including Alzheimer's disease (AD). Loganin, an iridoid glycoside obtained from traditional Chinese medicine Cornus officinalis, has properties of inhibiting inflammation and improving memory. The present study was ai...

journal_title：Cell biology international

authors： Cui Y,Wang Y,Zhao D,Feng X,Zhang L,Liu C

更新日期：2018-12-01 00:00:00

abstract：:A convenient means of measuring apoptosis is described using an automated analyzer (MF-1; Sysmex), which normally provides rapid measurement of malarial parasites. By means of this MF-1 procedure, apoptotic cells exhibited characteristic changes of light scatter (size) and fluorescence (DNA content) relating to cell s...

journal_title：Cell biology international

authors： Lertworasirikul T,Bunyaratvej A,Kubota F

更新日期：2000-01-01 00:00:00

abstract：:Annexin I is an abundant cytosolic protein in human neutrophils. Besides its intracellular location, annexin I is found as an extracellular protein and the pathway for secretion has been of interest since the protein lacks a signal sequence for secretion. It was recently shown that annexin I is stored in the secretory...

journal_title：Cell biology international

authors： Movitz C,Dahlgren C

更新日期：2001-01-01 00:00:00

abstract：:The possible role of protein kinase C (PKC) and mitogen activated protein (MAP) kinases in the stimulation of cholesterol esterification by acetylated low density lipoprotein (acLDL) in human monocyte-derived macrophages (HMDM) was studied. Cholesterol esterification, as assessed by the rate of incorporation of [3H]-o...

journal_title：Cell biology international

authors： Napolitano M,Avella M,Goode NT,Botham KM,Bravo E

更新日期：2004-01-01 00:00:00

abstract：:MicroRNA-21 (miR-21) was reported to act as an oncogene during the development of many human tumors. However, little was revealed about the function of miR-21 in retinoblastoma (RB). In this study, we examined the expression of miR-21 in RB tissues and explored the relationship between miR-21 and phosphatase and tensi...

journal_title：Cell biology international

authors： Gui F,Hong Z,You Z,Wu H,Zhang Y

更新日期：2016-12-01 00:00:00

abstract：:Growing evidence has shown that apelin/APJ system functions as a critical mediator of cardiac development as well as cardiovascular function. Here, we investigated the role of apelin in the cardiomyogenic differentiation of mesenchymal stem cells derived from Wharton's jelly of human umbilical cord in vitro. In this r...

journal_title：Cell biology international

authors： Wang L,Zhu ZM,Zhang NK,Fang ZR,Xu XH,Zheng N,Gao LR

更新日期：2016-05-01 00:00:00

abstract：:Carpal tunnel syndrome (CTS) is a compression median nerve neuropathy common in women at menopausal age. The aim of this work was to study immunohistochemically the expression of estrogen (ER) and progesterone (PR) receptors in CTS and control specimens. Biopsies of transverse carpal ligament (TCL) and flexor tendon s...

journal_title：Cell biology international

authors： Toesca A,Pagnotta A,Zumbo A,Sadun R

更新日期：2008-01-01 00:00:00

abstract：:Mesenchymal stem cells (MSCs) and endothelial progenitor cells (EPCs) are attached to each other in the bone marrow (BM) cavity and in in vitro cultures, and this adhesion has important physiological significance. We demonstrated that cell proliferation could be promoted when MSCs were co-cultured with EPCs, which was...

journal_title：Cell biology international

authors： Xia J,Zhang H,Gao X,Guo J,Hou J,Wang X,Wang S,Yang T,Zhang X,Ge Q,Wan L,Cheng W,Zheng J,Chen X,Wu X

更新日期：2016-04-01 00:00:00

abstract：:Large numbers of autogenous melanocytes (Mcs) are required when conducting studies on tissue engineering of skin and performing surgical treatment of depigmentation diseases. This study was conducted to explore the possibility of inducing differentiation of bone marrow mesenchymal stem cells (MSCs) into Mcs as a means...

journal_title：Cell biology international

authors： Mei X,Sun Y,Wu Z,Pan W,Zhu J,Shi W

更新日期：2015-07-01 00:00:00

abstract：:An effect of magnesium on calcium-induced depolarisation of mitochondrial transmembrane potential (DeltaPsi(m)) was investigated. Depending on the presence of Mg(2+), addition of Ca(2+) to suspension of isolated rat heart mitochondria induced either reversible depolarisation or irreversible collapse of succinate-drive...

journal_title：Cell biology international

authors： Racay P

更新日期：2008-01-01 00:00:00

abstract：:Epidermis, a continuously renewing tissue, is maintained by stem cells that proliferate and replenish worn out or damaged cells in the tissue during life. Cultured epidermal stem cells have great potential in scientific research and clinical application. However, isolating a pure and viable population of epidermal ste...

journal_title：Cell biology international

authors： Zhou JX,Jia LW,Yang YJ,Peng S,Cao YJ,Duan EK

更新日期：2004-01-01 00:00:00

abstract：:With rapid development of space engineering, research on life sciences in space is being conducted extensively, especially cellular and molecular studies on space medicine. Stem cells, undifferentiated cells that can differentiate into specialized cells, are considered a key resource for regenerative medicine. Researc...

journal_title：Cell biology international

authors： Zhang C,Li L,Chen J,Wang J

更新日期：2015-06-01 00:00:00

abstract：:Osteocalcin is one of the most abundant non-collagenous proteins in bone that is commonly used as a preliminary biomarker in bone formation. Osteocalcin also regulates energy metabolism as a hormone. Estrogen-related receptor alpha (ERRα) is primarily thought to regulate energy homeostasis through interacting with per...

journal_title：Cell biology international

authors： Wang H,Wang J

更新日期：2013-11-01 00:00:00