Single amino acid mutations in the Saccharomyces cerevisiae rhomboid peptidase, Pcp1p, alter mitochondrial morphology.

abstract：:Neural stem cells (NSCs) are currently considered powerful candidates for cell therapy in neurodegenerative disorders such as Parkinson's disease. However, it is not known when and how NSCs begin to differentiate functionally. Recent reports suggest that classical neurotransmitters such as acetylcholine (Ach) are invo...

journal_title：Cell biology international

authors： Zhou C,Wen ZX,Shi DM,Xie ZP

更新日期：2004-01-01 00:00:00

abstract：:Earlier, we have shown that spontaneously isolated non-pathogenic bacteria Serratia grimesii and Serratia proteamaculans invade eukaryotic cells, provided that they synthesize thermolysin-like metalloproteases ECP32/grimelysin or protealysin characterized by high specificity towards actin. To address the question of w...

journal_title：Cell biology international

authors： Bozhokina ES,Tsaplina OA,Efremova TN,Kever LV,Demidyuk IV,Kostrov SV,Adam T,Komissarchik YY,Khaitlina SY

更新日期：2011-02-01 00:00:00

abstract：:Stem cell therapy in recent years has gained much attention as the modern therapeutic approach to treat diseases. Mesenchymal stem cells (MSCs) are seen as the most reliable cells applied in therapy over other stem cells because of their versatility. Bone and cartilage diseases (osteo-diseases) are the major target of...

journal_title：Cell biology international

authors： Ghasroldasht MM,Irfan-Maqsood M,Matin MM,Bidkhori HR,Naderi-Meshkin H,Moradi A,Bahrami AR

更新日期：2014-10-01 00:00:00

abstract：:A plant transformation and selection system has been developed utilizing a modified tubulin gene as a selectable marker. The vector constructs carrying a mutant alpha-tubulin gene from goosegrass conferring resistance to dinitroaniline herbicides were created for transformation of monocotyledonous and dicotyledonous p...

journal_title：Cell biology international

authors： Yemets A,Radchuk V,Bayer O,Bayer G,Pakhomov A,Vance Baird W,Blume YB

更新日期：2008-05-01 00:00:00

abstract：:The present study was undertaken to test the reproducible formation of the extended chromatin fibres (ECF), beads and superbeads, and detect molecular order and crystallinity by optical anisotropies in those structures. Chicken erythrocyte smears and mouse liver cell imprints were treated with 2.0-3.0 m NaCl solution ...

journal_title：Cell biology international

authors： de Campos Vidal B

更新日期：2000-01-01 00:00:00

abstract：:MMP-9 participates in tumour growth, invasion, metastasis and vascularisation. Thus, inhibition of MMP-9 may be involved in the process of tumourigenesis. We have investigated the effect of RNAi-mediated MMP-9 silencing on inhibiting invasion and migration of mouse melanoma cell B16. A specific and optimised siRNA vec...

journal_title：Cell biology international

authors： Tang ZY,Liu Y,Liu LX,Ding XY,Zhang H,Fang LQ

更新日期：2013-08-01 00:00:00

abstract：:In the presence of low density lipoprotein (LDL), Chlamydia pneumoniae induces macrophage-derived foam cell formation, a typical pathological feature of early atherosclerosis. However, its mechanism has not been fully understood. Peroxisome proliferator-activated receptors (PPARs) are key regulators of macrophage lipi...

journal_title：Cell biology international

authors： Mei CL,He P,Cheng B,Liu W,Wang YF,Wan JJ

更新日期：2009-03-01 00:00:00

abstract：:To better treat patients with non-small cell lung cancer (NSCLC), the investigations on novel molecules affecting NSCLC progression are of vital importance. Long noncoding RNAs (lncRNAs) are identified as pivotal regulators that can affect the cellular activities of carcinomas. Long intergenic non-protein coding RNA 6...

journal_title：Cell biology international

authors： Yang H,Yang W,Dai W,Ma Y,Zhang G

更新日期：2020-08-01 00:00:00

abstract：:Prostate cancer is a life-threatening condition worldwide. As the tumor progresses, smooth muscle cells (SMCs) become atrophic/dedifferentiated, within a series of stromal changes named stromal reaction. Here, we tested whether a laminin 111-rich extracellular matrix (Lr-ECM) could affect SMCs phenotype and differenti...

journal_title：Cell biology international

authors： Osório DA,Consonni SR,Dos Santos AM,Carvalho HF

更新日期：2020-12-30 00:00:00

abstract：:Neuroblastoma is one of the most common solid tumours in children (8-10% of all malignancies). Over 22% of cases have N-myc amplification associated with aggressively growing neuroblastomas. Oncogene-induced sensitization of cells to apoptosis is an important mechanism for suppression of tumorigenesis. Tumour suppress...

journal_title：Cell biology international

authors： Li T,Wang L,Ke XX,Gong XY,Wan JH,Hao XW,Xu M,Xiang Z,Cui ZB,Cui H

更新日期：2012-04-01 00:00:00

abstract：:Tripartite motif-containing 22 (TRIM22) is reported to participate in numerous cellular activities. Recent studies confirm that TRIM22 is a target gene for P53, and inhibits clonogenic growth of leukemic U-937 cells. The current study aims to discover the effect of TRIM22 in progression of human chronic myeloid leukem...

journal_title：Cell biology international

authors： Li L,Qi Y,Ma X,Xiong G,Wang L,Bao C

更新日期：2018-09-01 00:00:00

abstract：:Cell behaviour in 3D environments can be significantly different from those in 2D cultures. With many different 3D matrices being developed and many experimental modalities used to modulate cell behaviour in 3D, it is necessary to develop high throughput techniques to study behaviour in 3D. We report on a 3D array on ...

journal_title：Cell biology international

authors： Zhao S,Gao R,Devreotes PN,Mogilner A,Zhao M

更新日期：2013-09-01 00:00:00

abstract：:The microbicidal capacity of the macrophage is frequently evaded by mycobacteria, leading to tuberculosis (TB). We investigated a number of parameters affecting the rate of growth of mycobacteria in human monocyte-derived macrophages (MDM). The results show a great deal of variation in the growth of both Mycobacterium...

journal_title：Cell biology international

authors： Hoal-van Helden EG,Hon D,Lewis LA,Beyers N,van Helden PD

更新日期：2001-01-01 00:00:00

abstract：:Cutaneous squamous cell carcinoma (SCC) is a malignant tumour of keratinising epidermal cells. This type of skin cancer is the second leading cause of death after melanoma, and it is the second most common type of non-melanoma skin cancer after basal cell carcinoma. The cellular and molecular events involved in the pr...

journal_title：Cell biology international

authors： Salehi Z,Mashayekhi F,Shahosseini F

更新日期：2007-11-01 00:00:00

abstract：:Continuous variation in the direction of the gravity vector leads to various cellular responses including modulation of gene expression. Complementary DNA (cDNA) array analyses are available to observe the variation of gene expression under different conditions. In this study, expression levels of 588 representative g...

journal_title：Cell biology international

authors： Arase Y,Nomura J,Sugaya S,Sugita K,Kita K,Suzuki N

更新日期：2002-01-01 00:00:00

abstract：:The objective of this study was to determine if adenosine alters growth of mammary epithelium. Mouse mammary epithelial cells (NMuMG) were cultured in DMEM supplemented with 10% fetal calf serum. After serum starvation for 24 h, EGF (0-100 ng/ml) and/or adenosine (0-100 microM) was added. Adenosine at concentrations o...

journal_title：Cell biology international

authors： Yuh IS,Jang BB,Hong BJ

更新日期：1998-01-01 00:00:00

abstract：:Coumarin and its derivative 7-hydroxycoumarin (7-OHC) have antitumor and antimetastatic properties. The purpose of this study was to investigate the possible effects of these compounds on expression of the bcl-2 and Bax oncoproteins in two human lung cancer cell lines, A427 and Calu-1. The cells were cultured in vitro...

journal_title：Cell biology international

authors： Elinos-Báez CM,León F,Santos E

更新日期：2005-08-01 00:00:00

abstract：:Fibrillin-1 is the major component of extracellular matrix microfibrils. Microfibrils dysfunction is responsible for the onset of various connective tissue diseases, including Marfan syndrome. Although ADAMTSL (a disintegrin and metalloproteinase with thrombospondin motifs-like) 6β is one of the fibrillin-1 binding pr...

journal_title：Cell biology international

authors： Orimoto A,Fukuda T

更新日期：2020-07-01 00:00:00

abstract：:Non-transformed epitheliocytes and fibroblasts undergo modulations between the less polarised and more polarised phenotypes depending on the nature of the substrate. In contrast, transformed cells express polarised phenotype regardless of the substrate. ...

journal_title：Cell biology international

authors： Moizhess TG,Vasiliev JM

更新日期：2001-01-01 00:00:00

abstract：:microRNAs (miRNAs) have recently been recognized as playing an important role in bone-associated diseases. This study investigated whether the reduced miR-155-5p in steroid-associated osteonecrosis of the femoral head (ONFH) attenuated osteogenic differentiation and cell proliferation by targeting GSK3B. Bone marrow w...

journal_title：Cell biology international

authors： Wu F,Huang W,Yang Y,Liu F,Chen J,Wang G,Sun Z

更新日期：2021-01-01 00:00:00

abstract：:Ro52/SSA is an autoantigen that presents in patients with SS (Sjögren's syndrome) and SLE (systemic lupus erythematosus). It increases cell death and redistributes itself to apoptotic blebs, but its pro-apoptotic function has not been completely identified. Overexpression of Ro52/SSA promoted cell apoptosis induced by...

journal_title：Cell biology international

authors： Zhang J,Fang L,Zhu X,Qiao Y,Yu M,Wang L,Chen Y,Yin W,Hua ZC

更新日期：2012-05-01 00:00:00

abstract：:Glycolipid patterns have been studied during the first six days of Xenopus embryo development. Glycolipid contents showed a sharp increase more evident after the third day of development. Glucosylceramide and sulphatide are not only the most represented species, but also those which exhibit a statistically significant...

journal_title：Cell biology international

authors： Gornati R,Rizzo AM,Tong XW,Berra B,Bernardini G

更新日期：1995-03-01 00:00:00

abstract：:Restriction Endonucleases (REs) may recognize, cleave and remove DNA from fixed chromatin producing specific chromosome banding patterns. However, the modifications produced in the chromatin fibre are not easy to evaluate and compare. The aim of the present investigation was to visualize differences resulting in the t...

journal_title：Cell biology international

authors： Gosálvez J,López-Fernández C,Fernández JL,Goyanes VJ,Buño I

更新日期：1996-03-01 00:00:00

abstract：:A structural link between cell's nucleus and centrosome was proposed years ago. Such a link was suggested to maintain nucleus-centrosome axis, determine polarity of interphase cells and ensure spindle assembly in mitotic cells. The idea of structural link is supported by the facts that centrosomes are usually located ...

journal_title：Cell biology international

authors： Burakov AV,Nadezhdina ES

更新日期：2013-02-01 00:00:00

abstract：:The pharmacological modulation of collagen turnover is a strategy potentially useful in different skin conditions. The serine protease inhibitor Serpin A1 and portions of its C-terminal region have been investigated as collagen modulators. To clarify the mechanisms by which the C-terminal 409-418 peptide SA1-III incre...

journal_title：Cell biology international

authors： Cipriani C,Pascarella S,Errante F,Menicacci B,Magnelli L,Mocali A,Rovero P,Giovannelli L

更新日期：2018-09-01 00:00:00

abstract：:The mitogenic effect of TGF-alpha, acidic-FGF, basic-FGF and lithium on normal human breast epithelial cells was studied in a collagen gel culture system using a serum-free 1:1 mixture of Ham's F12 and DME medium containing insulin, cholera toxin and bovine serum albumin. TGF-alpha elicited a strong mitogenic response...

journal_title：Cell biology international

authors： Sakthivel R,Hamdan M,Yang J,Guzman RC,Nandi S

更新日期：1993-04-01 00:00:00

abstract：:Conventional kinesin is an ATPase-active motor protein that is involved in the microtubule-dependent transport of cytoplasmic cargoes. The present paper provides a condensed overview on kinesin-1 and its motility generation outside a living cell. Moreover, it demonstrates that the neuron-specific kinesin KIF5A enables...

journal_title：Cell biology international

authors： Böhm KJ

更新日期：2008-05-01 00:00:00

abstract：:The interaction of NO and O2- free radicals generated from PMA (phorbol myristate acetate)-stimulated PMN (polymorphonuclear leukocytes) was studied by a nitroxide spin trap, DMPO (5,5-dimethyl-1-pyrroline-1-oxide). It was found that addition of L-arginine to the system would significantly decrease the trapped O2- by ...

journal_title：Cell biology international

authors： Zhao BL,Wang JC,Hou JW,Xin WJ

更新日期：1996-05-01 00:00:00

abstract：:The aim of this study was to examine the effects of glafenine hydrochloride (a nonsteroidal anti-inflammatory drug) on proliferation, clonogenic activity, cell-cycle, migration, and the extracellular matrix protein tenascin of human aortic smooth muscle cells (haSMCs) and human endothelial cells (ECs) in vitro.HaSMCs ...

journal_title：Cell biology international

authors： Schöber W,Tran QB,Muringaseril M,Wiskirchen J,Kehlbach R,Rodegerdts E,Wiesinger B,Claussen CD,Duda SH

更新日期：2003-01-01 00:00:00

abstract：:Following genotoxic insult, p53 mutated tumour cells undergo mitotic catastrophe. This is characterised by a switch from mitosis to the endocycle. The essential difference between mitosis and the endocycle is that in the latter, DNA synthesis is uncoupled from cell division, which leads to the formation of endopolyplo...

journal_title：Cell biology international

authors： Erenpreisa J,Kalejs M,Cragg MS

更新日期：2005-12-01 00:00:00