Effect of TGF-alpha on growth of normal human breast epithelial cells in serum-free primary culture using 3-dimensional collagen gels.

abstract：:The induction and maintenance of immunologic tolerance at the feto-maternal interface is necessary for a successful pregnancy. The most accepted hypothesis for the mechanism underlying this tolerance is that pregnancy-induced foetal antigen-specific maternal T regulatory (T(reg) ) cells mediate maternal tolerance to t...

journal_title：Cell biology international

authors： Hao K,Zhou Q,Chen W,Jia W,Zheng J,Kang J,Wang K,Duan T

更新日期：2013-02-01 00:00:00

abstract：:Neural stem cells (NSCs) are currently considered powerful candidates for cell therapy in neurodegenerative disorders such as Parkinson's disease. However, it is not known when and how NSCs begin to differentiate functionally. Recent reports suggest that classical neurotransmitters such as acetylcholine (Ach) are invo...

journal_title：Cell biology international

authors： Zhou C,Wen ZX,Shi DM,Xie ZP

更新日期：2004-01-01 00:00:00

abstract：:Cytoplasmic proteins with binding capability to AU-rich instability determinant sequences (ARE) of tumour necrosis factor alpha (TNFalpha) mRNA 3' untranslated region (3'UTR) were assessed in human lymphoid cells. In vitro label transfer experiments using wild type as well as mutant sequences in which the 70 nucleotid...

journal_title：Cell biology international

authors： Henics T

更新日期：1999-01-01 00:00:00

abstract：:TZDs (thiazolidinediones) are prescribed as anti-Type II diabetes drugs, but little is known regarding whether TZDs regulate the expression of sPLA2 (secretory phospholipase A2) in macrophages. We have investigated the effects of pioglitazone on LPS (lipopolysaccharide)-induced production of TNF-alpha (tumour necrosis...

journal_title：Cell biology international

authors： Ao C,Huo Y,Qi L,Xiong Z,Xue L,Qi Y

更新日期：2010-07-01 00:00:00

abstract：:Electrotonic coupling among neurons in the vertebrate, and more specifically the mammalian, brain has now been demonstrated to exist in all major brain subdivisions and in the spinal cord. For many of these brain areas, recent studies have investigated the possibilities of modulation of that coupling by synaptically r...

journal_title：Cell biology international

authors： Hatton GI

更新日期：1998-11-01 00:00:00

abstract：:Hepatic heat shock protein Hsp70 synthesis and in vitro phosphorylation were studied in the liver cytosol of intact, adrenalectomized and dexamethasone-administered adrenalectomized rats after 41 degrees C whole body hyperthermic stress. Hsp70 was detected by immunoblotting with N27F3-4 monoclonal antibody recognizing...

journal_title：Cell biology international

authors： Cvoro A,Dundjerski J,Trajković D,Matić G

更新日期：1999-01-01 00:00:00

abstract：:Propofol is one of the extensively commonly used intravenous anaesthetic agents. The effects of Propofol on hepatocellular carcinoma (HCC) growth inhibition and apoptosis have been examined. The techniques used were the MTT assay, flow cytometry, real-time PCR to assess miR-199a expression, as also caspase-8 and caspa...

journal_title：Cell biology international

authors： Zhang J,Wu GQ,Zhang Y,Feng ZY,Zhu SM

更新日期：2013-03-01 00:00:00

abstract：:Phosphoserine has potential effectiveness as a simple substrate in preparing bone replacement materials, which could enhance bone forming ability. However, there is a need to investigate the independent effect of phosphoserine on osteogenic differentiation of human adipose stem cells (hADSCs). hADSCs were cultured in ...

journal_title：Cell biology international

authors： Ying X,Chen X,Cheng S,Guo X,Chen H,Xu HZ

更新日期：2014-03-01 00:00:00

abstract：:Breast cancer is one of the most common cancers in the female population worldwide, and its development is thought to be associated with genetic mutations that lead to uncontrolled and accelerated growth of breast cells. This abnormal behavior requires extra energy, and indeed, tumor cells display a rewired energy met...

journal_title：Cell biology international

authors： Lacerda-Abreu MA,Russo-Abrahão T,Leite Tenório Aguiar R,Monteiro RQ,Rumjanek FD,Meyer-Fernandes JR

更新日期：2020-11-03 00:00:00

abstract：:Annexin I is an abundant cytosolic protein in human neutrophils. Besides its intracellular location, annexin I is found as an extracellular protein and the pathway for secretion has been of interest since the protein lacks a signal sequence for secretion. It was recently shown that annexin I is stored in the secretory...

journal_title：Cell biology international

authors： Movitz C,Dahlgren C

更新日期：2001-01-01 00:00:00

abstract：:Previous trials performed in our laboratory have demonstrated that stainless steel corrosion products induced morphological changes in mice seminiferous cells. In this study the functional nature of the blood-testis barrier was investigated, in view of the extensive use of this metallic alloy in orthopaedic surgery. T...

journal_title：Cell biology international

authors： Pereira ML

更新日期：1995-07-01 00:00:00

abstract：:Cell behaviour in 3D environments can be significantly different from those in 2D cultures. With many different 3D matrices being developed and many experimental modalities used to modulate cell behaviour in 3D, it is necessary to develop high throughput techniques to study behaviour in 3D. We report on a 3D array on ...

journal_title：Cell biology international

authors： Zhao S,Gao R,Devreotes PN,Mogilner A,Zhao M

更新日期：2013-09-01 00:00:00

abstract：:Ca(2+)mobilization induced by ATP, isoproterenol and the Ca(2+)-ATPase inhibitor thapsigargin in the human submandibular duct cell line A253 was investigated using the Ca(2+)-sensitive fluorescent indicator fura-2. ATP and isoproterenol increased cytosolic free Ca(2+)([Ca(2+)](i)) and subsequent exposure to thapsigarg...

journal_title：Cell biology international

authors： Andersson C,Zhang AL,Roomans GM

更新日期：2000-01-01 00:00:00

abstract：:DNA is constantly being damaged, either by endogenous or exogenous genotoxins. In that regard, DNA repair activities are essential for maintaining genomic stability and to life itself. Mutations in genes encoding DNA repair proteins cause severe human syndromes, but DNA repair defects have also been linked to several ...

journal_title：Cell biology international

authors： Prates Mori M,de Souza-Pinto NC

更新日期：2018-06-01 00:00:00

abstract：:The size and number of secretory granules in late larval salivary glands of Drosophila melanogaster have been related to interecdysial and early metamorphic development represented by well-known puffs in polytene chromosomes. Interecdysial period (puff stage 1 (PS1)) is characterized by presence of numerous small gran...

journal_title：Cell biology international

authors： Farkas R,Suáková G

更新日期：1999-01-01 00:00:00

abstract：:Insulin resistance, diabetes and many kinds of cancers are common in overweight and obese individuals. The tumor suppressor p53 is important in securing genetic stability, but its role in the regulation of metabolic processes and cell differentiation remains unclear. We have investigated the role of p53 in adipocyte d...

journal_title：Cell biology international

authors： Huang Q,Liu M,Du X,Zhang R,Xue Y,Zhang Y,Zhu W,Li D,Zhao A,Liu Y

更新日期：2014-12-01 00:00:00

abstract：:Restriction Endonucleases (REs) may recognize, cleave and remove DNA from fixed chromatin producing specific chromosome banding patterns. However, the modifications produced in the chromatin fibre are not easy to evaluate and compare. The aim of the present investigation was to visualize differences resulting in the t...

journal_title：Cell biology international

authors： Gosálvez J,López-Fernández C,Fernández JL,Goyanes VJ,Buño I

更新日期：1996-03-01 00:00:00

abstract：:Expression of four major reprogramming transgenes, including Oct4, Sox2, Klf4 and c-myc, in somatic cells enables them to have pluripotency. These cells are iPSC (induced pluripotent stem cell) that currently show the greatest potential for differentiation into cells of the three germ lineages. One of the issues facin...

journal_title：Cell biology international

authors： Shoae-Hassani A,Sharif S,Verdi J

更新日期：2011-10-01 00:00:00

abstract：:Wnt signalling regulates cell proliferation and cell fate determination during embryogenesis. However, little is known about the developmental role of one Wnt family member, Wnt-3, during avian development. To investigate the possible functions of Wnt-3, its expression pattern was determined using whole-mount in situ ...

journal_title：Cell biology international

authors： Dongkyun K,Jinsoo S,Jin EJ

更新日期：2010-07-01 00:00:00

abstract：:ROS (reactive oxygen species) take an important signalling role in angiogenesis. Although there are several ways to produce ROS in cells, multicomponent non-phagocytic NADPH oxidase is an important source of ROS that contribute to angiogenesis. In the present work, we examined the effects of H2O2 on angiogenesis inclu...

journal_title：Cell biology international

authors： Mu P,Liu Q,Zheng R

更新日期：2010-10-01 00:00:00

abstract：:Our aim has been to elucidate the possible mechanism of CJX1, an amlodipine derivative, in the modulation of P-gp function by determining its effect on P-gp ATPase activity. Basal P-gp ATPase activity was increased by CJX1 with half-maximal activity concentration (Km) of 8.6+/-1.4 microM. Kinetic analysis indicated a ...

journal_title：Cell biology international

authors： Ji BS,He L

更新日期：2009-10-01 00:00:00

abstract：:The efficacies of chemotherapeutic agents are often limited by side effects and acquired drug resistance. We have investigated whether the differential expression pattern of 14-3-3σ affects cisplatin response in non-small cell lung cancer cell lines. Two pairs of parental/cisplatin resistant cell lines (A549/CRA549 an...

journal_title：Cell biology international

authors： Cetintas VB,Tetik A,Cok G,Kucukaslan AS,Kosova B,Gunduz C,Veral A,Eroglu Z

更新日期：2013-01-01 00:00:00

abstract：:MMP-9 participates in tumour growth, invasion, metastasis and vascularisation. Thus, inhibition of MMP-9 may be involved in the process of tumourigenesis. We have investigated the effect of RNAi-mediated MMP-9 silencing on inhibiting invasion and migration of mouse melanoma cell B16. A specific and optimised siRNA vec...

journal_title：Cell biology international

authors： Tang ZY,Liu Y,Liu LX,Ding XY,Zhang H,Fang LQ

更新日期：2013-08-01 00:00:00

abstract：:Disconnected interacting protein 2 (DIP2) is a highly conserved protein family among invertebrates and vertebrates, but its function remains unclear. In this paper, we summarized the conservation of gene sequences and protein domains of DIP2 family members and predicted that they may have a similar functional role in ...

journal_title：Cell biology international

authors： Ma J,Chen L,He XX,Wang YJ,Yu HL,He ZX,Zhang LQ,Zheng YW,Zhu XJ

更新日期：2019-04-01 00:00:00

abstract：:The aim of this study was to determine the polarization of macrophages in the tumor microenvironment, as well as the effect of soluble factors secreted from these polarized macrophages on etoposide-induced cancer cell apoptosis. We investigated the effect of soluble factors secreted from the supernatant of PC3 cells t...

journal_title：Cell biology international

authors： Malekghasemi S,Majidi J,Baradaran B,Aghebati-Maleki L

更新日期：2020-10-01 00:00:00

abstract：:Rb/E2F regulates many genes that encode proteins required for the cell cycle. Using affymetrix microarrays we previously identified genes regulated by the Rb proteins p130 and p107, many of which are involved in the cell cycle. Several genes with unknown functions were also repressed by p130 and p107, of which some ha...

journal_title：Cell biology international

authors： Date DA,Jacob CJ,Bekier ME,Stiff AC,Jackson MW,Taylor WR

更新日期：2007-12-01 00:00:00

abstract：:We investigated the effect of triptolide (TP) on spinal cord injury (SCI), and its underlying mechanism. Following the establishment of the SCI model using YFP H-line transgenic mice, TP was intraperitoneally injected at a dose of 0.2 mg/kg once daily for 7 days. Behavioral tests, Nissl staining, and hematoxylin-eosin...

journal_title：Cell biology international

authors： Zhu N,Ruan J,Yang X,Huang Y,Jiang Y,Wang Y,Cai D,Geng Y,Fang M

更新日期：2020-03-01 00:00:00

abstract：:Esophageal squamous cell carcinoma (ESCC) belongs to one of the most common malignant tumors worldwide and possesses high mortality. Long non-coding RNAs (lncRNAs) have been demonstrated to be essential biological participants in the progression of ESCC. On the basis of bio-informatics prediction, forkhead box P4 anti...

journal_title：Cell biology international

authors： Li Y,Li T,Yang Y,Kang W,Dong S,Cheng S

更新日期：2020-07-01 00:00:00

abstract：:Kallikrein 14 (KLK14) is a serine protease linked to several pathologies including prostate cancer and positively correlates with Gleason score. Though KLK14 functioning in cancer is poorly understood, it has been implicated in HGF/Met signaling, given that KLK14 proteolytically inhibits HGF activator-inhibitor 1 (HAI...

journal_title：Cell biology international

authors： Solís-Calero C,Carvalho HF

更新日期：2017-11-01 00:00:00

abstract：:Cell therapy and regenerative medicine are potentially two of the most exciting aspects of the novel therapeutic methods currently under development. However, these treatments present a number of important biosafety issues, like the possible transmission of microorganisms to the recipients. The most common potential f...

journal_title：Cell biology international

authors： Cobo F,Cortés JL,Cabrera C,Nieto A,Concha A

更新日期：2007-09-01 00:00:00