Automated detection of morphological alterations during apoptosis.

abstract：:Inflammatory cytokines exert different effects on hematopoietic stem cells (HSCs), lead to the development of various cell lineages in bone marrow (BM) and are thus a differentiation axis for HSCs. The content used in this article has been obtained by searching PubMed database and Google Scholar search engine of Engli...

journal_title：Cell biology international

authors： Najafi S,Ghanavat M,Shahrabi S,Gatavizadeh Z,Saki N

更新日期：2021-01-02 00:00:00

abstract：:BPD (bronchopulmonary dysplasia) is predominantly characterized by persistent abnormalities in lung structure and arrested lung development, but therapy can be palliative. While promising, the use of BMSC (bone marrow-derived mesenchymal stem cell) in the treatment of lung diseases remains controversial. We have asses...

journal_title：Cell biology international

authors： Zhang X,Wang H,Shi Y,Peng W,Zhang S,Zhang W,Xu J,Mei Y,Feng Z

更新日期：2012-06-01 00:00:00

abstract：:Chloride secretion in primary cultures of cells originating from the secretory coil of human sweat glands was investigated by electron probe X-ray microanalysis. The total intracellular Cl concentration was lowered by muscarinic agonists (carbachol and acetylcholine), as well as by the calcium ionophore A23187. The mu...

journal_title：Cell biology international

authors： Mörk AC,Hongpaisan J,Roomans GM

更新日期：1995-02-01 00:00:00

abstract：:This study examined whether Gd (gadolinium) could suppress prostate cancer cell migration and prostate cancer cell-induced osteoclast differentiation. MTT [3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-2H-tetrazolium bromide] and colony forming assay showed that GdCl3 treatment inhibited both cell viability and colony for...

journal_title：Cell biology international

authors： Wang P,Zou XM,Huang J,Zhang TL,Wang K

更新日期：2011-11-01 00:00:00

abstract：:IPF is characterized by fibroblast accumulation, collagen deposition, and ECM remodeling, with myofibroblasts believed to be the effector cell type. Myofibroblasts develop due to EMT of lung alveolar epithelial cells, which can be induced by TGF-β. M2 macrophages, a macrophage subpopulation, secrete large amounts of T...

journal_title：Cell biology international

authors： Zhu L,Fu X,Chen X,Han X,Dong P

更新日期：2017-09-01 00:00:00

abstract：:Extracellular nucleotides cause neutrophil degranulation by activating the purinergic receptor subtype P2Y. However, the molecular mechanism involved in the signal pathway remains unknown. A hypothetical scheme suggesting that leukotriene(s) and leukotriene receptor(s) activation is required for extracellular nucleoti...

journal_title：Cell biology international

authors： Kannan S

更新日期：2003-01-01 00:00:00

abstract：:Genetic analysis has strongly implicated human FHIT (Fragile Histidine Triad) as a tumor suppressor gene, being mutated in a large proportion of early-stage cancers. The functions of the FHIT protein have, however, remained elusive. Here, we investigated aph1+ , the fission yeast homolog of FHIT, for functions related...

journal_title：Cell biology international

authors： Sjölander JJ,Sunnerhagen P

更新日期：2020-02-01 00:00:00

abstract：:Acylase 1 was investigated at the cellular level in the rat small intestine along the enterocyte-differentiation axis. As confirmed by microscopic analysis, villus tip cells and crypt cells of rat jejunal mucosa were successfully separated using the Weiser method. The proliferating undifferentiated crypt cells showed ...

journal_title：Cell biology international

authors： Cigna N,Nicoletti C,Durand A,Chaix JC,Giardina T,Perrier J

更新日期：2007-09-01 00:00:00

abstract：:A view is emerging that human amylin (HA) kills pancreatic islet beta-cells by apoptosis. This study strengthens this view by documenting time-dependent morphological and ultrastructural changes in 10 microm HA-treated cultured RINm5F islet beta-cells. Membrane blebbing and microvilli loss were the earliest detectable...

journal_title：Cell biology international

authors： Saafi EL,Konarkowska B,Zhang S,Kistler J,Cooper GJ

更新日期：2001-01-01 00:00:00

abstract：:Previous work on five cell types isolated from the bovine corpus luteum showed that the mass of acetylated microtubules (acet-MTs) in interphase differed. Endothelial cells, termed type 3, showed few acet-MTs, whereas the interphase cytoskeleton of granulosal-like cells, termed type 5, was rich in acet-MTs. In the pre...

journal_title：Cell biology international

authors： Wolf KW,Spanel-Borowski K

更新日期：1995-01-01 00:00:00

abstract：:Fibrinogen participates in important cellular physiological processes, such as cell adhesion and blood clotting. Although the primary and secondary structures of fibrinogen are known, its tertiary structure is yet to be determined. In attempts to understand the tertiary structure of this important hydrated cellular an...

journal_title：Cell biology international

authors： Taatjes DJ,Quinn AS,Jenny RJ,Hale P,Bovill EG,McDonagh J

更新日期：1997-11-01 00:00:00

abstract：:Oral squamous cell carcinoma (OSCC) is a serious global health problem. Recently, accumulating microRNA (miRNA) has emerged as crucial players in the development and progression of carcinomas including OSCC. Our study aimed to further investigate the roles of miR-140-5p in OSCC tumorigenesis and related molecular basi...

journal_title：Cell biology international

authors： Peng M,Pang C

更新日期：2019-08-08 00:00:00

abstract：:The neuropathology associated with Parkinson's disease (PD) is thought to involve excessive production of free radicals, dopamine autoxidation, defects in glutathione peroxidase expression, attenuated levels of reduced glutathione, altered calcium homeostasis, excitotoxicity and genetic defects in mitochondrial comple...

journal_title：Cell biology international

authors： González-Polo RA,Soler G,Rodríguezmartín A,Morán JM,Fuentes JM

更新日期：2004-01-01 00:00:00

abstract：:It has been reported that chronic inflammation of the vessel wall is a hallmark of atherosclerosis. Interleukin-6 (IL-6) is regarded as an important modulator of inflammatory events occurring during all stages of atherogenesis. Although many factors that induce IL-6 expression have been identified, the effect of homoc...

journal_title：Cell biology international

authors： Zhang L,Jin M,Hu XS,Zhu JH

更新日期：2006-07-01 00:00:00

abstract：:The efficacies of chemotherapeutic agents are often limited by side effects and acquired drug resistance. We have investigated whether the differential expression pattern of 14-3-3σ affects cisplatin response in non-small cell lung cancer cell lines. Two pairs of parental/cisplatin resistant cell lines (A549/CRA549 an...

journal_title：Cell biology international

authors： Cetintas VB,Tetik A,Cok G,Kucukaslan AS,Kosova B,Gunduz C,Veral A,Eroglu Z

更新日期：2013-01-01 00:00:00

abstract：:The number of the nucleoli in a CaCo-2 cell nucleus does not generally depend on the quantity of DNA in the nucleus, but nucleolar DNA content is directly proportional to total nuclear DNA. However, in multinucleolar cells (three or more nucleoli), the nucleolar DNA content increases after 96 h incubation in culture w...

journal_title：Cell biology international

authors： Karalyan ZA,Djaghatspanyan NG,Gasparyan MH,Hakobyan LA,Abroyan LO,Magakyan YH,Ter-Pogossyan ZR,Kamalyan LA,Karalova EM

更新日期：2004-01-01 00:00:00

abstract：:Most traditional cytotoxic chemotherapeutic agents have poor aqueous solubility and significant toxicity. Hence, there is a need to develop molecule-targeted drugs. Programmed death-ligand 1 (PD-L1) is associated with the prognosis of several cancer types, and blockade of PD-1/PD-L1 signaling increases the amplitude o...

journal_title：Cell biology international

authors： Liu K,Zhou Z,Gao H,Yang F,Qian Y,Jin H,Guo Y,Liu Y,Li H,Zhang C,Guo J,Wan Y,Chen R

更新日期：2019-06-01 00:00:00

abstract：:vasa (vas)-related genes are members of the DEAD-box protein family and are expressed in the germ cells of many Metazoa. We cloned vasa-related genes (PpVLG, CpVLG) and other DEAD-box family related genes (PpDRH1, PpDRH2, CpDRH, AtDRHr) from the colonial parasitic rhizocephalan barnacle Polyascus polygenea, the non-co...

journal_title：Cell biology international

authors： Shukalyuk AI,Golovnina KA,Baiborodin SI,Gunbin KV,Blinov AG,Isaeva VV

更新日期：2007-02-01 00:00:00

abstract：:The cytosolic lipid droplets (cLDs) store excess intracellular lipids, and perilipin-2 is believed to protect cLDs from degradation. Here, we investigated the role of the small G-protein Arf1 and the proteasome in the fates of perilipin-2 and cLDs. In oleate-loaded cells, upon brefeldin A (BFA) treatment, perilipin-2 ...

journal_title：Cell biology international

authors： Pauloin A,Adenot P,Hue-Beauvais C,Chanat E

更新日期：2016-02-01 00:00:00

abstract：:We have investigated constitutive endocytosis in internodal cells of the characean green algae. The endocytic tracer FM1-43 accumulated in distinct plasma membrane domains that are probably enriched in sterol-like substances. Internalization of the dye was active but independent of an intact actin or microtubule cytos...

journal_title：Cell biology international

authors： Foissner I,Klima A

更新日期：2008-05-01 00:00:00

abstract：:The present study was undertaken to test the reproducible formation of the extended chromatin fibres (ECF), beads and superbeads, and detect molecular order and crystallinity by optical anisotropies in those structures. Chicken erythrocyte smears and mouse liver cell imprints were treated with 2.0-3.0 m NaCl solution ...

journal_title：Cell biology international

authors： de Campos Vidal B

更新日期：2000-01-01 00:00:00

abstract：:Our study aimed to explore the function of cystic fibrosis transmembrane conductance regulator (CFTR) in esophageal cancer. Twenty patients with esophageal squamous cell carcinoma (ESCC) and 20 patients with esophageal adenocarcinoma (EA) were enrolled in this study. The levels of CFTR and NF-κB in tumor tissues and a...

journal_title：Cell biology international

authors： Li W,Wang C,Peng X,Zhang H,Huang H,Liu H

更新日期：2018-12-01 00:00:00

abstract：:We have characterised, using both in vivo and in vitro methods, the effects of the metabotropic glutamate receptor subtype 3 (mGlu3) antagonist (LY341495) and agonist (LY379268) on the proliferation and differentiation of glioma stem cells (GSC). For in vitro studies, a CCK-8 assay was used to determine the cell proli...

journal_title：Cell biology international

authors： Zhou K,Song Y,Zhou W,Zhang C,Shu H,Yang H,Wang B

更新日期：2014-04-01 00:00:00

abstract：:Glutamyl aminopeptidase (GluAP, EC 3.4.11.7, ENPEP) is a 130-kDa homodimeric zinc metallopeptidase which specifically cleaves the N-terminal glutamate or aspartate residue of peptidic substrates such as cholecystokinin-8 or angiotensin (Ang) II, in vitro. We used a DNA microarray hybridization (Genechip Rat Expression...

journal_title：Cell biology international

authors： Wu Y,Xiao J,Wu L,Tian W,Liu L

更新日期：2008-07-01 00:00:00

abstract：:Adipocyte lines are a useful tool for adipocyte research. Recently, a new preadipocyte line designated AP-18 was established from subcutaneous tissue of the C3H/He mouse. In this study, we further characterized AP-18 cells. Adipocyte differentiation was assessed by accumulation of fat droplets stained by Oil Red O. Th...

journal_title：Cell biology international

authors： Chen C,Takahashi K,Yoshida A,Takizawa Y,Lee Y,Nakui M,Doi H,Takebayashi Y,Fukumoto M,Yamada T,Katagiri H,Oka Y,Satoh J

更新日期：2010-02-22 00:00:00

abstract：:Under the 1G condition, the increase in antipain-sensitive protease activity promptly after UV (mainly 254 nm wavelength) irradiation in cultured human cells is detected and found to be one of the intriguing events involved in suppression of cell mutability. It was found that two cell lines, RSa and its variant UVAP-1...

journal_title：Cell biology international

authors： Takahashi S,Zhang HC,Hasegawa R,Karata K,Kita K,Wano C,Yamaguchi Y,Sugaya S,Nomura J,Ichinose M,Suzuki N

更新日期：2003-01-01 00:00:00

abstract：:Here we report a homologue of the apolipoprotein D gene (AmphiApoD) in amphioxus, Branchiostoma belcheri tsingtauense, the first such finding in a basal chordate cephalochordate. The main features of the protein predicted from AmphiApoD are characteristic of the apolipoprotein D. Phylogenetic analysis places AmphiApoD...

journal_title：Cell biology international

authors： Wang L,Zhang S,Liu Z,Li H,Wang Y,Jiang S

更新日期：2007-01-01 00:00:00

abstract：:Forms of the protozoan of the Hepatozoon genus are detected free in the circulation and also within some of the erythrocytes of infected snakes. In healthy snakes, DNA fragmentation and cell death usually affect a few circulating erythrocytes in agreement with the long life span expected for these cells. In the presen...

journal_title：Cell biology international

authors： Miyamoto M,Mello ML

更新日期：2007-05-01 00:00:00

abstract：:Growth hormone (GH), given therapeutically in many human diseases, is able to modulate the maturation and function of many cells of immune system. The present study demonstrates the effect of human recombinant GH on the production of acute phase proteins (APP) as well as on the gene expression of junB proto-oncogene o...

journal_title：Cell biology international

authors： Derfalvi B,Igaz P,Fulop KA,Szalai C,Falus A

更新日期：2000-01-01 00:00:00

abstract：:Type I diabetes is characterized by the deficiency of endocrine beta cells in the pancreatic islets of Langerhans and transplantation of islet cells can be an effective therapeutic approach. Embryonic stem cells can be differentiated into any cell type, and therefore represent an unlimited source of islet cells for th...

journal_title：Cell biology international

authors： Chen C,Zhang Y,Sheng X,Huang C,Zang YQ

更新日期：2008-04-01 00:00:00