Morphometry of nuclear and nucleolar structures in a CaCo-2 cell line.

abstract：:The focal adhesion protein vinculin has been implicated in associating with soluble and membranous phospholipids. Detailed investigations over the past ten years describe the intermolecular interactions of the vinculin tail domain with soluble and membrane phospholipids. Previous studies have implied that the tail's u...

journal_title：Cell biology international

authors： Goldmann WH

更新日期：2018-08-01 00:00:00

abstract：:Trophoblast cells play a vital role in embryo implantation. Exploring cytokines secreted by trophoblast cells will be significant in revealing the molecular mechanism of embryo implantation. In vitro-cultured trophoblast cells treated with Lefty revealed that Lefty could downregulate the expression of Nodal while prom...

journal_title：Cell biology international

authors： Li H,Cao R,Bai L,Qiao XM,Zhao YQ

更新日期：2018-09-01 00:00:00

abstract：:Ischemic stroke is a major common cause of death and long-term disability worldwide. Several pathophysiological events including excitotoxicity, oxidative/nitrative stress, inflammation, and apoptosis are involved in ischemic injuries. Recently, the molecular mechanisms involved in cerebral ischemia through a focus on...

journal_title：Cell biology international

authors： Behdarvandy M,Karimian M,Atlasi MA,Azami Tameh A

更新日期：2020-02-01 00:00:00

abstract：:Embryonic development depends on the normal invasion of trophoblast cells. Forkhead box C2 (FOXC2) is a member of Forkhead box family, which is involved in the tumor cells invasion. The aim of this study was to explore the roles of FOXC2 on the invasion of human trophoblast cells, and further study its molecular mecha...

journal_title：Cell biology international

authors： Zhang Y,Zhang Y

更新日期：2018-07-01 00:00:00

abstract：:Rosbin (Thieno [2, 3-c] piperidine-3-carboxamide-2-[(3-methoxy-naphtha-lene-2-carbonyl)-amino]-6-(benzyl)-, hydrochloride), a synthetic piperidinothieno derivative compound obtained from chemical genetics screenings, significantly suppresses the viability of non-small cell lung cancer A549 cells with an IC50 of 2.05 ±...

journal_title：Cell biology international

authors： Zhao T,Jin W,Pan H,Li H,Zhao Y,Feng Y

更新日期：2017-02-01 00:00:00

abstract：:Following culture of human peripheral blood mononuclear cells (PBMNC) from 25 normal donors and 15 patients with common variable immunodeficiency (CVID), we were unable to identify any IL10-defective patients. Clear-cut effects of IL4 could be demonstrated in controls, while in CVID all effects are less pronounced. Wh...

journal_title：Cell biology international

authors： Fritsch A,Junker U,Vogelsang H,Jager L

更新日期：1994-11-01 00:00:00

abstract：:The unicellular Tetrahymena has receptors for hormones of higher vertebrates, produces these hormones, and their signal pathways are similar. The first encounter with a hormone in higher dose provokes the phenomenon of hormonal imprinting, by which the reaction of the cell is quantitatively modified. This modification...

journal_title：Cell biology international

authors： Kőhidai L,Lajkó E,Pállinger E,Csaba G

更新日期：2012-10-01 00:00:00

abstract：:Although clinical data suggest remarkable promise for targeting programmed cell death protein-1 (PD-1) and ligand (PD-L1) signaling in non-small-cell lung cancer (NSCLC), it is still largely undetermined which subtype of patients will be responsive to checkpoint blockade. In the present study, we explored whether PD-L...

journal_title：Cell biology international

authors： Pan LN,Ma YF,Li Z,Hu JA,Xu ZH

更新日期：2020-12-15 00:00:00

abstract：:The purpose of this study was three fold: (1) to reveal the implications of Wnt5A for cytokine and chemokine production by human ovarian cancer cell line SKOV-3 cells, (2) to determine the influence of Wnt5A on chemotactic SKOV-3 cell migration, and (3) to assess the effect of inflammatory mediators on Wnt5A expressio...

journal_title：Cell biology international

authors： Arabzadeh S,Hossein G,Zarnani AH

更新日期：2016-02-01 00:00:00

abstract：:The effect of an organochlorine pesticide benzene hexachloride (containing alpha, beta, gamma and delta isomers) on the phagocytic activity of the vegetative cells of Dictyostelium discoideum was investigated. Benzene hexachloride (BHC) at concentrations of 60 ppm and above inhibited the phagocytic activity as reveale...

journal_title：Cell biology international

authors： Gayatri R,Chatterjee S

更新日期：1993-03-01 00:00:00

abstract：:Peritoneal dialysis (PD) is often used to treat patients with end stage renal disease, and its long-term complications include excessive inflammation and oxidative stress. Allograft inflammatory factor 1 (AIF-1), as a cytoplasmic protein, is originally identified from infiltrating macrophages, and it was associated wi...

journal_title：Cell biology international

authors： Zhou Y,Li X,Yuan X,Hao L

更新日期：2019-05-01 00:00:00

abstract：:Menstrual blood is easily accessible, renewable, and inexpensive source of stem cells that have been interested for cell therapy of neurodegenerative diseases. In this study, we showed conversion of menstrual blood stem cells (MenSCs) into clonogenic neurosphere- like cells (NSCs), which can be differentiated into gli...

journal_title：Cell biology international

authors： Azedi F,Kazemnejad S,Zarnani AH,Behzadi G,Vasei M,Khanmohammadi M,Khanjani S,Edalatkhah H,Lakpour N

更新日期：2014-05-01 00:00:00

abstract：:Restriction Endonucleases (REs) may recognize, cleave and remove DNA from fixed chromatin producing specific chromosome banding patterns. However, the modifications produced in the chromatin fibre are not easy to evaluate and compare. The aim of the present investigation was to visualize differences resulting in the t...

journal_title：Cell biology international

authors： Gosálvez J,López-Fernández C,Fernández JL,Goyanes VJ,Buño I

更新日期：1996-03-01 00:00:00

abstract：:Observations made in live cells have clearly demonstrated that agonist-activated steroid/nuclear receptors reorganize in the nucleoplasm into hundreds of discrete speckled structures commonly referred to as nuclear foci. Subsequent studies have shown that nuclear foci are formed only with agonist- and not with pure an...

journal_title：Cell biology international

authors： Kumar S,Saradhi M,Chaturvedi NK,Tyagi RK

更新日期：2012-02-01 00:00:00

abstract：:TNF-α has long been implicated in the progression of rheumatoid arthritis (RA). However, how the receptors of TNF-α, namely TNFR1 and TNFR2, mediate TNF-α-induced inflammatory responses in fibroblast-like synoviocytes (FLS) in RA has not been elucidated. In the present study, primary FLS cells were isolated from RA pa...

journal_title：Cell biology international

authors： Zhang H,Xiao W

更新日期：2017-04-01 00:00:00

abstract：:ZO-1 is a peripheral protein that plays a central role in the macromolecular assembly of tight junctions by interacting with integral proteins (occludin, claudins, JAMs) of the membrane of adjoining cells, with the actin cytoskeleton, and with nuclear factors. Human ZO-1 is expressed in all epithelia and some speciali...

journal_title：Cell biology international

authors： Ciana A,Meier K,Daum N,Gerbes S,Veith M,Lehr CM,Minetti G

更新日期：2010-05-07 00:00:00

abstract：:The isolation and culture of articular chondrocytes is a prerequisite of their use in tissue engineering, but prolonged culture and passaging is associated with de-differentiation. In this paper we studied the influence of nanometric and micrometric grooves (85 nm to 8 microm in depth and 2 microm to 20 microm in widt...

journal_title：Cell biology international

authors： Hamilton DW,Riehle MO,Monaghan W,Curtis AS

更新日期：2005-06-01 00:00:00

abstract：:Introns of plant tubulin genes are useful molecular tools to study IME (Intron Mediated Enhancement of gene expression) and to define plant genetic and evolutionary relationships through ILP (Intron Length Polymorphism). Here we show that the intron present within the 5'UTR sequence of some rice beta-tubulin genes can...

journal_title：Cell biology international

authors： Breviario D,Gianì S,Ponzoni E,Mastromauro F,Morello L

更新日期：2008-05-01 00:00:00

abstract：:Long non-coding RNAs (lncRNAs) are involved in regulating chromatin modifications, gene transcription, mRNA translation, and protein function. We recently reported a high variation in the basal expression levels of a panel of lncRNAs in HeLa and MCF-7 cells and their differential response to DNA damage induction. Here...

journal_title：Cell biology international

authors： Gezer U,Özgür E,Cetinkaya M,Isin M,Dalay N

更新日期：2014-09-01 00:00:00

abstract：:A combination of in vivo UV light-induced crosslinking of nucleic acids to proteins and in vitro label transfer assay was applied to investigate specific interactions between AU-rich sequences (ARE) in the 3' UTR of lymphokine mRNAs and cytoplasmic AU-rich sequence element binding proteins (AUBP) in normal human lymph...

journal_title：Cell biology international

authors： Henics T,Nagy E,Rigby WF

更新日期：1995-09-01 00:00:00

abstract：:Reactive oxygen species (ROS) are not only generated in conditions of cellular stress but are also constitutively produced in most cell types by specific metabolic processes. This research focused on a potential antioxidant Trolox (model compound for alpha-tocopherol), with the aim to establish exact mechanisms of Tro...

journal_title：Cell biology international

authors： Raspor P,Plesnicar S,Gazdag Z,Pesti M,Miklavcic M,Lah B,Logar-Marinsek R,Poljsak B

更新日期：2005-01-01 00:00:00

abstract：:BPD (bronchopulmonary dysplasia) is predominantly characterized by persistent abnormalities in lung structure and arrested lung development, but therapy can be palliative. While promising, the use of BMSC (bone marrow-derived mesenchymal stem cell) in the treatment of lung diseases remains controversial. We have asses...

journal_title：Cell biology international

authors： Zhang X,Wang H,Shi Y,Peng W,Zhang S,Zhang W,Xu J,Mei Y,Feng Z

更新日期：2012-06-01 00:00:00

abstract：:Receptor-interacting serine/threonine kinase 4 (RIPK4) and transforming growth factor-β 1 (TGF-β1) play critical roles in the development and maintenance of the epidermis. A negative correlation between the expression patterns of RIPK4 and TGF-β signaling during epidermal homeostasis-related events and suppression of ...

journal_title：Cell biology international

authors： Dinçer T,Boz Er AB,Er İ,Toraman B,Yildiz G,Kalay E

更新日期：2020-03-01 00:00:00

abstract：:Calmodulin-like skin protein (CLSP) is a secreted peptide that is produced by skin keratinocytes and some related epithelial cells. It has previously been shown that CLSP is recruited via the bloodstream into the central nervous system where it likely exerts a neuroprotective effect against toxicity related to Alzheim...

journal_title：Cell biology international

authors： Takahara Y,Miyachi N,Nawa M,Matsuoka M

更新日期：2019-07-01 00:00:00

abstract：:DNA is constantly being damaged, either by endogenous or exogenous genotoxins. In that regard, DNA repair activities are essential for maintaining genomic stability and to life itself. Mutations in genes encoding DNA repair proteins cause severe human syndromes, but DNA repair defects have also been linked to several ...

journal_title：Cell biology international

authors： Prates Mori M,de Souza-Pinto NC

更新日期：2018-06-01 00:00:00

abstract：:The influence of oxygen tension on the side population (SP) fraction sorted from ATDC5 chondroprogenitor cells was investigated. ATDC5 cells cultured in normoxia (20%) or hypoxia (1% oxygen) were compared. The SP fraction was significantly higher in the cells cultured in hypoxia. The gene expression of 3 ABC transport...

journal_title：Cell biology international

authors： Kishimoto KN,Oxford CL,Reddi AH

更新日期：2009-12-01 00:00:00

abstract：:The mdx mouse has been used as an animal model for human Duchenne muscular dystrophy (DMD). Unlike DMD, skeletal muscles of mdx mice undergo successful regeneration and do not show extensive fibrosis and functional impairment. Growth factors have been proposed to be involved in muscle growth and regeneration. We compa...

journal_title：Cell biology international

authors： Chen G,Bressler BH,Quinn LS

更新日期：1994-04-01 00:00:00

abstract：:Bradykinin (1 microM) and histamine (100 microM) evoked an initial transient increase and a subsequent sustained increase in intracellular Ca(2+) concentration ([Ca(2+)](i)) in fura-2-loaded human gingival fibroblasts, which may be attributed to Ca(2+) release from intracellular stores and Ca(2+) entry from extracellu...

journal_title：Cell biology international

authors： Ogata Y,Nakao S,Shimizu E,Matsuda-Honjyo Y,Yamazaki M,Furuyama S,Sugiya H

更新日期：2003-01-01 00:00:00

abstract：:The exon 16-encoded juxtamembrane (JM) domain of human insulin receptor (hIR) harbors the NPEY motif which couples the insulin-activated hIR kinase to downstream signal transduction molecules. We sought to determine if signal transduction requires the entire exon 16-encoded 22-amino acid JM domain. Transfected CHO cel...

journal_title：Cell biology international

authors： Sattar AA,Berhanu C,Gebreselassie S,Berhanu P

更新日期：2007-08-01 00:00:00

abstract：:Mitomycin C (MMC) treatment has been used to arrest cell proliferation but not much is known about the effect of MMC on human foreskin fibroblasts (HFF) used as feeders for human embryonic stem cells (hESC). We tested the ability of MMC to stop the proliferation of HFF and to induce apoptosis. MMC inhibited the prolif...

journal_title：Cell biology international

authors： Nieto A,Cabrera CM,Catalina P,Cobo F,Barnie A,Cortés JL,Barroso del Jesus A,Montes R,Concha A

更新日期：2007-03-01 00:00:00