M2 macrophages induce EMT through the TGF-β/Smad2 signaling pathway.

abstract：:The spatial distribution of acid membrane organelles and their relationships with normal and vacuolated transverse tubules has been studied in living frog skeletal muscle fibres using confocal microscopy. Acridine orange (AO) was used to evaluate acid compartments, while a lipophilic styryl dye, RH 414, was employed t...

journal_title：Cell biology international

authors： Krolenko SA,Adamyan SY,Belyaeva TN,Mozhenok TP

更新日期：2006-11-01 00:00:00

abstract：:In order to investigate the effects of human yolk sac-derived endothelial cells (hYSECs) on the expansion of human hematopoietic stem/progenitor cells (HS/PCs) from umbilical cord blood (UCB) in vitro, we purified hYSEC-like cells from 4-5 week human yolk sacs, which were morphologically similar to endothelial cells a...

journal_title：Cell biology international

authors： Hu L,Cheng L,Wang J,Zhao H,Duan H,Lu G

更新日期：2006-11-01 00:00:00

abstract：:Breast cancer is one of the most common cancers in the female population worldwide, and its development is thought to be associated with genetic mutations that lead to uncontrolled and accelerated growth of breast cells. This abnormal behavior requires extra energy, and indeed, tumor cells display a rewired energy met...

journal_title：Cell biology international

authors： Lacerda-Abreu MA,Russo-Abrahão T,Leite Tenório Aguiar R,Monteiro RQ,Rumjanek FD,Meyer-Fernandes JR

更新日期：2020-11-03 00:00:00

abstract：:MicroRNA-21 (miR-21) was reported to act as an oncogene during the development of many human tumors. However, little was revealed about the function of miR-21 in retinoblastoma (RB). In this study, we examined the expression of miR-21 in RB tissues and explored the relationship between miR-21 and phosphatase and tensi...

journal_title：Cell biology international

authors： Gui F,Hong Z,You Z,Wu H,Zhang Y

更新日期：2016-12-01 00:00:00

abstract：:Chloride secretion in primary cultures of cells originating from the secretory coil of human sweat glands was investigated by electron probe X-ray microanalysis. The total intracellular Cl concentration was lowered by muscarinic agonists (carbachol and acetylcholine), as well as by the calcium ionophore A23187. The mu...

journal_title：Cell biology international

authors： Mörk AC,Hongpaisan J,Roomans GM

更新日期：1995-02-01 00:00:00

abstract：:Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is a key enzyme of the glycolytic pathway. Recent studies have demonstrated an additional role in apoptosis: GAPDH is targeted to the nucleus during apoptotic signalling. This nuclear transport has also been observed in serum-depleted cells, but it is reversible in fibr...

journal_title：Cell biology international

authors： Schmitz HD,Dutiné C,Bereiter-Hahn J

更新日期：2003-01-01 00:00:00

abstract：:While much evidence indicates a high degree of spatial organization in the nucleus, the underlying molecular structures that support it remain poorly characterized. By extracting with high concentrations of RNase A in a modification of the sequential extraction protocol of Penman, we have identified a novel intranucle...

journal_title：Cell biology international

authors： Padros MR,Giles DM,Suarez MD

更新日期：1997-06-01 00:00:00

abstract：:A number of pathophysiological conditions are related to iron metabolism disturbances. Some of them are well known, others are newly discovered or special. Hepcidin is a newly identified iron metabolism regulating hormone, which could be a promising biomarker for many disorders. In this review, we provide background i...

journal_title：Cell biology international

authors： Miseta A,Nagy J,Nagy T,Poór VS,Fekete Z,Sipos K

更新日期：2015-11-01 00:00:00

abstract：:Neuroblastoma is the most common tumor diagnosed in children and infants, with high recurrence and poor prognosis. Angelica sinensis polysaccharide (AP) whose average molecular weight is 72,900 Da possesses various bioactivities. We aimed to explore the effects of AP on neuroblastoma SH-SY5Y cells as well as the under...

journal_title：Cell biology international

authors： Yang J,Shao X,Jiang J,Sun Y,Wang L,Sun L

更新日期：2018-07-01 00:00:00

abstract：:Toxoplasma gondii is an obligate intracellular pathogen, replicating only within a specialized membrane-bounded cytoplasmic vacuole, the parasitophorous vacuole (PV), which interacts with host cell mitochondria. High mobility group box 1 (HMGB1), a known nuclear transcription factor, also may be involved in pathologic...

journal_title：Cell biology international

authors： Stumbo AC,Cortez E,Rodrigues CA,Henriques Md,Porto LC,Barbosa HS,Carvalho L

更新日期：2008-02-01 00:00:00

abstract：:The single-minded 2 gene (Sim2) plays a crucial role in the mental retardation of Down Syndrome (DS). To explore how Sim2 influences spatial memory, a DNA plasmid-encoding mouse Sim2 (mSim2) wrapped with liposome was bilaterally injected into the hippocampus of rats. The effect of overexpressing mSim2 on spatial learn...

journal_title：Cell biology international

authors： Meng X,Peng B,Shi J,Zheng Y,Chen H,Zhang J,Li L,Zhang C

更新日期：2006-10-01 00:00:00

abstract：:The size and number of secretory granules in late larval salivary glands of Drosophila melanogaster have been related to interecdysial and early metamorphic development represented by well-known puffs in polytene chromosomes. Interecdysial period (puff stage 1 (PS1)) is characterized by presence of numerous small gran...

journal_title：Cell biology international

authors： Farkas R,Suáková G

更新日期：1999-01-01 00:00:00

abstract：:GDNF plays an important role in the survival and differentiation of primary dopaminergic neurons, but it requires multiple factors for its entire range of activities. This study investigated the effects of GDNF and its cofactors on the development of bFGF-responsive neural progenitor cells (NPCs), mesencephalic and co...

journal_title：Cell biology international

authors： Sun ZH,Lai YL,Li P,Zuo HC,Xie ZP

更新日期：2004-01-01 00:00:00

abstract：:Glycometabolism, particularly mitochondrial oxidative phosphorylation (OXPHOS) and glycolysis, plays a central role in cell life activities. Glycometabolism can be reprogrammed to maintain the stemness or to induce the differentiation of stem cells, thereby regulating tissue repair and regeneration. However, research ...

journal_title：Cell biology international

authors： Wang L,Cheng L,Wang H,Pan H,Yang H,Shao M,Hu T

更新日期：2016-03-01 00:00:00

abstract：:A method based on the measurement at room temperature of tryptophan phosphorescence (RTTP) gives the unique possibility to investigate the dynamic structure of membrane proteins without their isolation from cells. This method was used to study the influence of tert- butyl hydroperoxide (t -BHP) on Chinese hamster fibr...

journal_title：Cell biology international

authors： Mazhul V,Shcherbin D,Zavodnik I,Rekawiecka K,Bryszewska M

更新日期：1999-01-01 00:00:00

abstract：:Although several species of Tetrahymena are often described as histophagous and opportunistic pathogens of fish, little is known about ciliate/fish cell interactions, but one approach for studying these is in vitro with cell lines. In this study, T. thermophila, B1975 (wild type) and NP1 (temperature sensitive mutant ...

journal_title：Cell biology international

authors： Pinheiro MD,Bols NC

更新日期：2014-10-01 00:00:00

abstract：:Insulin-like growth factor-1 (IGF-1) is a positive regulator in proliferation and differentiation of skeletal muscle cells, while myostatin (MSTN) is a member of transforming growth factor beta superfamily that acts as a negative regulator of skeletal muscle mass. The present study was performed to detail whether a co...

journal_title：Cell biology international

authors： Miyake M,Hayashi S,Sato T,Taketa Y,Watanabe K,Hayashi S,Tanaka S,Ohwada S,Aso H,Yamaguchi T

更新日期：2007-10-01 00:00:00

abstract：:The biosynthesis of interleukin-6 receptor (IL-6R) and gp130 in vitro was blocked using specific antisense oligonucleotides (ASO) in HepG2 liver cells and the efficacy of various ASOs was tested on the generation of IL-6-induced junB mRNA. We used three ASOs specific for the IL-6 receptor, three specific for gp130 and...

journal_title：Cell biology international

authors： Varga VL,Fülöp AK,Holub MC,Tóth S,Szalai C,Falus A

更新日期：2001-01-01 00:00:00

abstract：:Endothelial progenitor cells (EPCs) are precursor cells of vascular endothelial cells, which are widely involved in the pathological process of cardiovascular diseases. EPCs apoptosis could accelerate the process of cardiovascular diseases. 14-3-3-η protein has been proved to be a potent antiapoptosis molecule. Howeve...

journal_title：Cell biology international

authors： Li Y,Sun X,Zhang X,Zhou H,Wang D,Xia Y,Li X

更新日期：2020-12-15 00:00:00

abstract：:Earlier, we have shown that spontaneously isolated non-pathogenic bacteria Serratia grimesii and Serratia proteamaculans invade eukaryotic cells, provided that they synthesize thermolysin-like metalloproteases ECP32/grimelysin or protealysin characterized by high specificity towards actin. To address the question of w...

journal_title：Cell biology international

authors： Bozhokina ES,Tsaplina OA,Efremova TN,Kever LV,Demidyuk IV,Kostrov SV,Adam T,Komissarchik YY,Khaitlina SY

更新日期：2011-02-01 00:00:00

abstract：:We have characterised, using both in vivo and in vitro methods, the effects of the metabotropic glutamate receptor subtype 3 (mGlu3) antagonist (LY341495) and agonist (LY379268) on the proliferation and differentiation of glioma stem cells (GSC). For in vitro studies, a CCK-8 assay was used to determine the cell proli...

journal_title：Cell biology international

authors： Zhou K,Song Y,Zhou W,Zhang C,Shu H,Yang H,Wang B

更新日期：2014-04-01 00:00:00

abstract：:Inner ear cells, including hair cells, spiral ganglion cells, stria vascularis cells and supporting cells on the basilar membrane, play a major role in transducing hearing signals and regulating inner ear homoeostasis. However, their functions are often damaged by antibiotic-induced ototoxicity. Apoptosis is probably ...

journal_title：Cell biology international

authors： Yu L,Tang H,Jiang XH,Tsang LL,Chung YW,Chan HC

更新日期：2010-12-01 00:00:00

abstract：:CO25 cells, a mouse myoblast line, contain multiple centrioles and primary cilia. A most unusual feature has been the finding of large numbers of separate structures in single cells-up to a maximum of nine centrioles, six primary cilia, and 12 of both organelles together. Aberrant multipolar spindles were occasionally...

journal_title：Cell biology international

authors： Zeytinoglu M,Ritter J,Wheatley DN,Warn RM

更新日期：1996-12-01 00:00:00

abstract：:Following genotoxic insult, p53 mutated tumour cells undergo mitotic catastrophe. This is characterised by a switch from mitosis to the endocycle. The essential difference between mitosis and the endocycle is that in the latter, DNA synthesis is uncoupled from cell division, which leads to the formation of endopolyplo...

journal_title：Cell biology international

authors： Erenpreisa J,Kalejs M,Cragg MS

更新日期：2005-12-01 00:00:00

abstract：:UCB (umbilical cord blood) as a resource of MSCs (mesenchymal stem cells) is widely accepted, but the quantity and characteristics of UCB-MSCs from different gestational ages have not been well studied. We have quantified the number of MSCs in UCB at different gestational ages using a multi-colour flowcytometer and co...

journal_title：Cell biology international

authors： Ma LL,Meng FB,Shi P,Li G,Pang XN

更新日期：2012-04-01 00:00:00

abstract：:Neuroinflammatory disorders such as Alzheimer's and Parkinson's diseases are characterised by chronic inflammation and loss of vascular integrity. Bradykinin 1 receptor (B1R) activation has been implicated in many neuroinflammatory diseases, but the contribution of B1R to inflammation and vascular breakdown is yet to ...

journal_title：Cell biology international

authors： Mugisho OO,Robilliard LD,Nicholson LFB,Graham ES,O'Carroll SJ

更新日期：2019-09-09 00:00:00

abstract：:Continuous variation in the direction of the gravity vector leads to various cellular responses including modulation of gene expression. Complementary DNA (cDNA) array analyses are available to observe the variation of gene expression under different conditions. In this study, expression levels of 588 representative g...

journal_title：Cell biology international

authors： Arase Y,Nomura J,Sugaya S,Sugita K,Kita K,Suzuki N

更新日期：2002-01-01 00:00:00

abstract：:Metallothioneins (MTs) are thought to participate in a wide variety of physiological roles, but the mechanisms involved are still unclear. The study was designed to examine the possible factors related to these mechanisms. Methods, including transfection, MTT assay and flow cytometry, were used to investigate the effe...

journal_title：Cell biology international

authors： Li J,Liu Y,Ru B

更新日期：2005-10-01 00:00:00

abstract：:Ro52/SSA is an autoantigen that presents in patients with SS (Sjögren's syndrome) and SLE (systemic lupus erythematosus). It increases cell death and redistributes itself to apoptotic blebs, but its pro-apoptotic function has not been completely identified. Overexpression of Ro52/SSA promoted cell apoptosis induced by...

journal_title：Cell biology international

authors： Zhang J,Fang L,Zhu X,Qiao Y,Yu M,Wang L,Chen Y,Yin W,Hua ZC

更新日期：2012-05-01 00:00:00

abstract：:The effects of NO in its environment may vary considerably depending on various factors. This study shows oxidative mechanism of cellular membrane alterations, which is not associated with triggering of ONOOH generation but is induced by pure NO. Our investigation examined the influence of low concentration of NO (0.1...

journal_title：Cell biology international

authors： Brzeszczynska J,Gwozdzinski K

更新日期：2008-01-01 00:00:00