Pigment epithelium-derived factor delays cellular senescence of human mesenchymal stem cells in vitro by reducing oxidative stress.

abstract：:Several synthetic decapeptides containing an HAV tripeptide motif were tested for their ability to modulate the enzymatic activity of rat extracellular SOD, an enzyme which also contains an HAV motif. Out of nine decapeptides that were tested, only a FGF-receptor derived peptide was active as a negative modulator of e...

journal_title：Cell biology international

authors： Willems J,Noppe W,Slegers H

更新日期：1995-11-01 00:00:00

abstract：:The authors examined the growth response of cardinal ligamental fibroblasts derived from patients with prolapsus uteri (HPLiF) and compared it with the response of those from control subjects (HCLiF). The growth rate during the logarithmic growth phase was not different between HPLiF and HCLiF, while the cell density ...

journal_title：Cell biology international

authors： Yamamoto M,Aoyagi M,Akazawa K,Tajima S,Yamamoto K

更新日期：1998-01-01 00:00:00

abstract：:G protein-coupled estrogen receptor (GPER) is recently identified as a membrane-associated estrogen receptor that mediates non-genomic effects of estrogen. Our previous immunohistochemistry study found an association between GPER and the proliferation of epithelial ovarian cancer. However, the contributions and mechan...

journal_title：Cell biology international

authors： Liu H,Yan Y,Wen H,Jiang X,Cao X,Zhang G,Liu G

更新日期：2014-05-01 00:00:00

abstract：:Bradykinin (1 microM) and histamine (100 microM) evoked an initial transient increase and a subsequent sustained increase in intracellular Ca(2+) concentration ([Ca(2+)](i)) in fura-2-loaded human gingival fibroblasts, which may be attributed to Ca(2+) release from intracellular stores and Ca(2+) entry from extracellu...

journal_title：Cell biology international

authors： Ogata Y,Nakao S,Shimizu E,Matsuda-Honjyo Y,Yamazaki M,Furuyama S,Sugiya H

更新日期：2003-01-01 00:00:00

abstract：:Non-small-cell carcinoma (NSCLC) is the most common cancer along with high mortality rate worldwide. In the present study, our data showed that lncRNA MAF BZIP Transcription Factor G Antisense RNA 1 (MAFG-AS1) was over-expressed in NSCLC tissues and cell lines. Overexpression of MAFG-AS1 promoted the migration, invasi...

journal_title：Cell biology international

authors： Jia YC,Wang JY,Liu YY,Li B,Guo H,Zang AM

更新日期：2019-04-01 00:00:00

abstract：:The single-minded 2 gene (Sim2) plays a crucial role in the mental retardation of Down Syndrome (DS). To explore how Sim2 influences spatial memory, a DNA plasmid-encoding mouse Sim2 (mSim2) wrapped with liposome was bilaterally injected into the hippocampus of rats. The effect of overexpressing mSim2 on spatial learn...

journal_title：Cell biology international

authors： Meng X,Peng B,Shi J,Zheng Y,Chen H,Zhang J,Li L,Zhang C

更新日期：2006-10-01 00:00:00

abstract：:In the past decades increasing lines of evidence have demonstrated that adipose tissue, as an endocrine organ plays a central role in metabolic homeostasis and its related maladies. CCAAT/enhancer-binding protein (C/EBP) family members and the nuclear receptor peroxisome proliferator-activated receptor gamma (PPARγ) w...

journal_title：Cell biology international

authors： Zhao XY,Chen XY,Zhang ZJ,Kang Y,Liao WM,Yu WH,Xiang AP

更新日期：2015-04-01 00:00:00

abstract：:The Kv2.1 potassium channel is a principal component of the delayed rectifier I(K) current in the pyramidal neurons of cortex and hippocampus. We used whole-cell patch-clamp recording techniques to systemically compare the electrophysiological properties between the native neuronal I(K) current of cultured rat hippoca...

journal_title：Cell biology international

authors： Liu M,Gong B,Qi Z

更新日期：2008-12-01 00:00:00

abstract：:We have studied the effect of enhanced expression of epithelial Na(+)channels (ENaC) on the ATP-induced Cl(-)secretion in the mouse epithelium using short-circuit current (I(SC)) and RT-PCR techniques. The amiloride sensitivity of basal current (I(b)) across the cultured endometrial epithelia was found to vary with th...

journal_title：Cell biology international

authors： Wang XF,Tsang LL,So SC,Chan HC

更新日期：2001-01-01 00:00:00

abstract：:As part of a programme of comparative measurements of Pd (diffusional water permeability) the RBCs (red blood cells) from dingo (Canis familiaris dingo) and greyhound dog (Canis familiaris) were studied. The morphologies of the dingo and greyhound RBCs [examined by light and SEM (scanning electron microscopy)] were fo...

journal_title：Cell biology international

authors： Benga G,Chapman BE,Matei H,Cox GC,Romeo T,Mironescu E,Kuchel PW

更新日期：2010-03-08 00:00:00

abstract：:This article has been withdrawn consistent with Elsevier Policy on Article Withdrawal (http://www.elsevier.com/locate/withdrawalpolicy). The Publisher apologizes for any inconvenience this may cause. ...

journal_title：Cell biology international

authors： Wang H,Huang Y

更新日期：2008-01-25 00:00:00

abstract：:Local anesthetic of bupivacaine may inhibit neurite outgrowth and induce apoptosis in mouse dorsal root ganglia (DRG) neurons. In this work, we intended to investigate the functional role of microRNA 26a (miR-26a) in regulating bupivacaine-induced nerve injury in DRG neurons. DRG neurons were extracted from C57BL/6 mi...

journal_title：Cell biology international

authors： Cui C,Xu G,Qiu J,Fan X

更新日期：2015-08-01 00:00:00

abstract：:The mitogen activated protein kinases (MAPK) signaling cascade plays an important role in cell life. We proved that small interfering RNAs targeting MAPK1 (siRNA-2) could inhibit HeLa cell growth, but the effects of siRNA-2 on gene expression profile were unclear. Using Affymetrix GeneChip HG-U133A 2.0, we identified ...

journal_title：Cell biology international

authors： Huang C,Liu LY,Li ZF,Wang P,Ni L,Song LP,Xu DH,Song TS

更新日期：2008-09-01 00:00:00

abstract：:This study examined whether Gd (gadolinium) could suppress prostate cancer cell migration and prostate cancer cell-induced osteoclast differentiation. MTT [3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-2H-tetrazolium bromide] and colony forming assay showed that GdCl3 treatment inhibited both cell viability and colony for...

journal_title：Cell biology international

authors： Wang P,Zou XM,Huang J,Zhang TL,Wang K

更新日期：2011-11-01 00:00:00

abstract：:Glycolipid patterns have been studied during the first six days of Xenopus embryo development. Glycolipid contents showed a sharp increase more evident after the third day of development. Glucosylceramide and sulphatide are not only the most represented species, but also those which exhibit a statistically significant...

journal_title：Cell biology international

authors： Gornati R,Rizzo AM,Tong XW,Berra B,Bernardini G

更新日期：1995-03-01 00:00:00

abstract：:Bisphosphonates (BPs), especially zoledronic acid (ZOL), are clinically used to treat osteolytic bone lesions. However, serious side-effects may be also induced during the therapeutic process. To improve the BPs drugs, here, we investigated the effects of a series of ZOL derivatives with increasing number of methylene...

journal_title：Cell biology international

authors： Peng Y,Liu Q,Xu D,Li K,Li H,Qiu L,Lin J

更新日期：2021-01-06 00:00:00

abstract：:Zinc-finger E-box binding homeobox 1 (ZEB1) is a master regulator of epithelial-mesenchymal transition (EMT) and has been implicated in primary epithelial cancer biological processes, such as invasion and metastasis. However, the role of ZEB1 in progression of melanoma and cancer stem cells (CSCs) remains obscure. In ...

journal_title：Cell biology international

authors： Dou J,He X,Liu Y,Wang Y,Zhao F,Wang X,Chen D,Shi F,Wang J

更新日期：2014-04-01 00:00:00

abstract：:Disconnected interacting protein 2 (DIP2) is a highly conserved protein family among invertebrates and vertebrates, but its function remains unclear. In this paper, we summarized the conservation of gene sequences and protein domains of DIP2 family members and predicted that they may have a similar functional role in ...

journal_title：Cell biology international

authors： Ma J,Chen L,He XX,Wang YJ,Yu HL,He ZX,Zhang LQ,Zheng YW,Zhu XJ

更新日期：2019-04-01 00:00:00

abstract：:FAM107B expression was decreased in stomach cancer and many other kinds of cancer. The forced expression of FAM107B in HeLa cells diminished proliferation in response to growth factors, suggesting that FAM107B might play important roles in many types of cancers. But the mechanisms underlying the decreased expression o...

journal_title：Cell biology international

authors： Guo J,Bian Y,Wang Y,Chen L,Yu A,Sun X

更新日期：2017-10-01 00:00:00

abstract：:A number of pathophysiological conditions are related to iron metabolism disturbances. Some of them are well known, others are newly discovered or special. Hepcidin is a newly identified iron metabolism regulating hormone, which could be a promising biomarker for many disorders. In this review, we provide background i...

journal_title：Cell biology international

authors： Miseta A,Nagy J,Nagy T,Poór VS,Fekete Z,Sipos K

更新日期：2015-11-01 00:00:00

abstract：:The influence of maternal nicotine exposure during pregnancy and lactation on the Type II cells of lung tissue of one day old neonatal rat pups was investigated. The results clearly show that maternal nicotine exposure resulted in an increase in the type II cell count in the lungs of the offspring. In addition the lam...

journal_title：Cell biology international

authors： Maritz GS,Thomas RA

更新日期：1995-04-01 00:00:00

abstract：:Many disturbances in electrolyte and hormonal balance in the body induced by functional impairment of renal parenchyma may affect the activity of amine precursor uptake and decarboxylation (APUD) cells, which constitute a very important link in the regulation of homeostasis. The aim of the present study was the morpho...

journal_title：Cell biology international

authors： Kasacka I

更新日期：2004-01-01 00:00:00

abstract：:Physical forces play a critical role in cell integrity and development, but little is known how cells convert mechanical signals into biochemical responses. This mini-review examines potential molecular mediators like integrins, focal adhesion proteins, and the cytoskeleton in the context of a complex cell structure. ...

journal_title：Cell biology international

authors： Goldmann WH

更新日期：2002-01-01 00:00:00

abstract：:The purpose of the study was to examine the effect of interleukins, IL-6, IL-8, and IL-15, on insulin-mediated redistribution of Rab4a, an early endosome marker, in mouse 3T3-L1 adipocytes. The interleukins did not affect cell viability; however, cell number was slightly but significantly higher in cultures exposed to...

journal_title：Cell biology international

authors： Błaszczyk M,Gajewska M,Milewska M,Grzelkowska-Kowalczyk K

更新日期：2017-04-01 00:00:00

abstract：:The low density lipoprotein receptor-related protein (alpha(2)MR/LRP) is a cell surface receptor which is present on most cells and tissues. We show that the 85 kDa subunit, containing the transmembrane region and cytoplasmic domain is phosphorylated in vivo. Comparison of the phosphorylation of the low density lipopr...

journal_title：Cell biology international

authors： Djordjevic JT,Waterkeyn JG,Hennessy KL,Stanley KK

更新日期：2000-01-01 00:00:00

abstract：:To better treat patients with non-small cell lung cancer (NSCLC), the investigations on novel molecules affecting NSCLC progression are of vital importance. Long noncoding RNAs (lncRNAs) are identified as pivotal regulators that can affect the cellular activities of carcinomas. Long intergenic non-protein coding RNA 6...

journal_title：Cell biology international

authors： Yang H,Yang W,Dai W,Ma Y,Zhang G

更新日期：2020-08-01 00:00:00

abstract：:Rosbin (Thieno [2, 3-c] piperidine-3-carboxamide-2-[(3-methoxy-naphtha-lene-2-carbonyl)-amino]-6-(benzyl)-, hydrochloride), a synthetic piperidinothieno derivative compound obtained from chemical genetics screenings, significantly suppresses the viability of non-small cell lung cancer A549 cells with an IC50 of 2.05 ±...

journal_title：Cell biology international

authors： Zhao T,Jin W,Pan H,Li H,Zhao Y,Feng Y

更新日期：2017-02-01 00:00:00

abstract：:We have successfully developed both spontaneous and inductive cardiomyocyte differentiation of iPS cells reprogrammed from human foreskin fibroblasts. The reprogrammed iPS cells morphologically resemble human cardiomyocytes which can beat. RT-PCR and immunostaining show that cardiac markers are expressed that are comp...

journal_title：Cell biology international

authors： Gai H,Leung EL,Costantino PD,Aguila JR,Nguyen DM,Fink LM,Ward DC,Ma Y

更新日期：2009-11-01 00:00:00

abstract：:The aliphatic polyamines, putrescine, spermine and spermidine belong to a category of molecules implicated in DNA replication. Their synthesis is strongly activated during the G1 period and they have been implicated in the regulation of cell proliferation and differentiation. Terminal transferase is a DNA polymerase p...

journal_title：Cell biology international

authors： Stabellini G,Rapino M,Di Primio R,Trubiani O

更新日期：1995-10-01 00:00:00

abstract：:CD25+Treg cells (CD4+CD25+Foxp3+ regulatory T cells) play a central role in the maintenance of peripheral self-tolerance and immune homoeostasis. A previous study showed that CD25+Treg cells suppressed the differentiation and function of Th1 cells in vivo and in vitro. However, the mechanism of suppressing Th1 cell di...

journal_title：Cell biology international

authors： Shen E,Zhao K,Wu C,Yang B

更新日期：2011-07-01 00:00:00