Establishment and characterization of endothelial cell lines from the aorta of miniature pig for the study of xenotransplantation.

abstract：:The aim of this study was to examine the effects of glafenine hydrochloride (a nonsteroidal anti-inflammatory drug) on proliferation, clonogenic activity, cell-cycle, migration, and the extracellular matrix protein tenascin of human aortic smooth muscle cells (haSMCs) and human endothelial cells (ECs) in vitro.HaSMCs ...

journal_title：Cell biology international

authors： Schöber W,Tran QB,Muringaseril M,Wiskirchen J,Kehlbach R,Rodegerdts E,Wiesinger B,Claussen CD,Duda SH

更新日期：2003-01-01 00:00:00

abstract：:Disconnected interacting protein 2 (DIP2) is a highly conserved protein family among invertebrates and vertebrates, but its function remains unclear. In this paper, we summarized the conservation of gene sequences and protein domains of DIP2 family members and predicted that they may have a similar functional role in ...

journal_title：Cell biology international

authors： Ma J,Chen L,He XX,Wang YJ,Yu HL,He ZX,Zhang LQ,Zheng YW,Zhu XJ

更新日期：2019-04-01 00:00:00

abstract：:Cadherins, being responsible for selective cell recognition and normal tissue integrity in adults, regulate morphogenesis in a variety of organs during development. In this study, anti-rat pan-cadherin antibody, specific to all subgroups of the cadherin family, was used to map the distribution of the pan-cadherin immu...

journal_title：Cell biology international

authors： Filiz S,Dalcik H,Yardimoglu M,Gonca S,Ceylan S

更新日期：2002-01-01 00:00:00

abstract：:Key to mitochondrial activities is the maintenance of mitochondrial morphology, specifically cristae structures formed by the invagination of the inner membrane that are enriched in proteins of the electron transport chain. In Saccharomyces cerevisiae , these cristae folds are a result of the membrane fusion activitie...

journal_title：Cell biology international

authors： Huddleston ME,Xiao N,Both AP,Gordon DM

更新日期：2019-08-23 00:00:00

abstract：:In 3D cultured cell systems, the cells form 3D spheroids that mimic cancer cell spheroids in vivo. Cancer cells form cell spheroids as they grow. The in vivo spheroids do not contain a vascular network; therefore, oxygen and nutrition supplies are insufficient. Specifically, the cells in the core region of the cluster...

journal_title：Cell biology international

authors： Terashima J,Sampei S,Iidzuka M,Ohsakama A,Tachikawa C,Satoh J,Kudo K,Habano W,Ozawa S

更新日期：2016-11-01 00:00:00

abstract：:Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is a key enzyme of the glycolytic pathway. Recent studies have demonstrated an additional role in apoptosis: GAPDH is targeted to the nucleus during apoptotic signalling. This nuclear transport has also been observed in serum-depleted cells, but it is reversible in fibr...

journal_title：Cell biology international

authors： Schmitz HD,Dutiné C,Bereiter-Hahn J

更新日期：2003-01-01 00:00:00

abstract：:G protein-coupled estrogen receptor (GPER) is recently identified as a membrane-associated estrogen receptor that mediates non-genomic effects of estrogen. Our previous immunohistochemistry study found an association between GPER and the proliferation of epithelial ovarian cancer. However, the contributions and mechan...

journal_title：Cell biology international

authors： Liu H,Yan Y,Wen H,Jiang X,Cao X,Zhang G,Liu G

更新日期：2014-05-01 00:00:00

abstract：:We analyzed whether the embryonic (E12.5-E14.5) mouse retina possesses genuine neural stem cells and how they respond to defined growth factors and extracellular matrix molecules. Whereas most combinations produced no or limited cell survival and proliferation in culture, FGF-2 plus heparin and laminin stimulated prol...

journal_title：Cell biology international

authors： Otaegi G,de Pablo F,Vicario-Abejón C,de la Rosa EJ

更新日期：2007-07-01 00:00:00

abstract：:CO25 cells, a mouse myoblast line, contain multiple centrioles and primary cilia. A most unusual feature has been the finding of large numbers of separate structures in single cells-up to a maximum of nine centrioles, six primary cilia, and 12 of both organelles together. Aberrant multipolar spindles were occasionally...

journal_title：Cell biology international

authors： Zeytinoglu M,Ritter J,Wheatley DN,Warn RM

更新日期：1996-12-01 00:00:00

abstract：:The introduction of four key transcriptional factors (CRX, RAX, NEURO-D, OTX2) allows the direct differentiation of fibroblasts to retinal photoreceptor cells. This reprogramming was achieved with a combination of mono-cistronic viruses. Although the combination of mono-cistronic viruses was useful, a relatively high ...

journal_title：Cell biology international

authors： Fukuda T,Ishizawa Y,Donai K,Sugano E,Tomita H

更新日期：2018-05-01 00:00:00

abstract：:In the present study, we investigated the effects of tetramethylpyrazine (TMP) on hydrogen peroxide (H2O2)-induced apoptosis in PC12 cells. The apoptosis in H2O2-induced PC12 cells was accompanied by a decrease in Bcl-2/Bax protein ratio, release of cytochrome c to cytosol and the activation of caspase-3. TMP not only...

journal_title：Cell biology international

authors： Cheng XR,Zhang L,Hu JJ,Sun L,Du GH

更新日期：2007-05-01 00:00:00

abstract：:At the early stage of atherosclerosis, neointima is formed due to the migration of vascular smooth muscle cells (VSMCs) from the media to the intima. VSMCs are surrounded by highly adhesive 3D matrices. They take specific strategies to cross various 3D matrices in the media, including heterogeneous collagen and mechan...

journal_title：Cell biology international

authors： Chi Q,Shan J,Ding X,Yin T,Wang Y,Jia D,Wang G

更新日期：2017-06-01 00:00:00

abstract：:Mutations in the lamin A gene have been shown, among other defects, to give rise to Hutchinson-Gilford progeria syndrome (HGPS) and to atypical Werner syndrome (WS), both of which are progeroid disorders. Here, we have investigated well-characterized WS patient cell strains that are compound heterozygous for mutations...

journal_title：Cell biology international

authors： Adelfalk C,Scherthan H,Hirsch-Kauffmann M,Schweiger M

更新日期：2005-12-01 00:00:00

abstract：:Transforming growth factor β1 (TGFβ1) is a negative regulator of hematopoiesis, and yet, it is frequently found at the active sites of hematopoiesis. Here, we show for the first time that bone marrow-derived mononuclear cells (BM MNCs) secrete TGFβ1 in response to erythropoietin (EPO). We further show that human bone ...

journal_title：Cell biology international

authors： Kale VP

更新日期：2020-11-01 00:00:00

abstract：:Aphidicolin, a selective inhibitor of DNA polymerase, totally blocks DNA replication in the micronucleus but not in the macronucleus of Paramecium caudatum. The ciliates no longer divide and after 4 days the DNA content of the macronucleus has increased by 64%. Concomitantly the cell volume has increased by 53%. ...

journal_title：Cell biology international

authors： Sabaneyeva E,Tao W,Verbelen JP

更新日期：1999-01-01 00:00:00

abstract：:As part of a programme of comparative measurements of Pd (diffusional water permeability) the RBCs (red blood cells) from dingo (Canis familiaris dingo) and greyhound dog (Canis familiaris) were studied. The morphologies of the dingo and greyhound RBCs [examined by light and SEM (scanning electron microscopy)] were fo...

journal_title：Cell biology international

authors： Benga G,Chapman BE,Matei H,Cox GC,Romeo T,Mironescu E,Kuchel PW

更新日期：2010-03-08 00:00:00

abstract：:Non-specific L-type calcium channel blockers, such as verapamil (> or =50 microM), induce metaphase-II (M-II) arrest and apoptosis in aged rat eggs cultured in Ca(2+)-deficient medium. However, the effects of extracellular Ca(2+) on verapamil-induced M-II arrest and apoptosis have not yet been reported. We have demons...

journal_title：Cell biology international

authors： Chaube SK,Tripathi A,Khatun S,Mishra SK,Prasad PV,Shrivastav TG

更新日期：2009-03-01 00:00:00

abstract：:Since contractility of the uterus appears to be the major source of pain during dysmenorrhoea, alleviation of the contractions is believed to be a possible treatment strategy. Bak Foong Pills, a traditional Chinese formulation for use in gynaecological disorders, has long been thought as effective in the treatment of ...

journal_title：Cell biology international

authors： Rowlands DK,Cui YG,Wong HY,Gou YL,Chan HC

更新日期：2009-12-01 00:00:00

abstract：:Cell behaviour in 3D environments can be significantly different from those in 2D cultures. With many different 3D matrices being developed and many experimental modalities used to modulate cell behaviour in 3D, it is necessary to develop high throughput techniques to study behaviour in 3D. We report on a 3D array on ...

journal_title：Cell biology international

authors： Zhao S,Gao R,Devreotes PN,Mogilner A,Zhao M

更新日期：2013-09-01 00:00:00

abstract：:The mdx mouse has been used as an animal model for human Duchenne muscular dystrophy (DMD). Unlike DMD, skeletal muscles of mdx mice undergo successful regeneration and do not show extensive fibrosis and functional impairment. Growth factors have been proposed to be involved in muscle growth and regeneration. We compa...

journal_title：Cell biology international

authors： Chen G,Bressler BH,Quinn LS

更新日期：1994-04-01 00:00:00

abstract：:Several synthetic decapeptides containing an HAV tripeptide motif were tested for their ability to modulate the enzymatic activity of rat extracellular SOD, an enzyme which also contains an HAV motif. Out of nine decapeptides that were tested, only a FGF-receptor derived peptide was active as a negative modulator of e...

journal_title：Cell biology international

authors： Willems J,Noppe W,Slegers H

更新日期：1995-11-01 00:00:00

abstract：:To characterize the cytoplasmic structure reorganization during plant meiosis, the male meiocytes of Althaea rosea (L.) Cavan were examined under the combination of light and electron microscopy. Light microscopic observation of the toluidine blue-stained thick resin sections of young anthers revealed that the meiocyt...

journal_title：Cell biology international

authors： Luo XJ,Liu XH,Wang CY,Wang XY

更新日期：2008-04-01 00:00:00

abstract：:Growing evidence has shown that apelin/APJ system functions as a critical mediator of cardiac development as well as cardiovascular function. Here, we investigated the role of apelin in the cardiomyogenic differentiation of mesenchymal stem cells derived from Wharton's jelly of human umbilical cord in vitro. In this r...

journal_title：Cell biology international

authors： Wang L,Zhu ZM,Zhang NK,Fang ZR,Xu XH,Zheng N,Gao LR

更新日期：2016-05-01 00:00:00

abstract：:Stem/progenitor cells hold promise for alleviating/curing type 1 diabetes due to the capacity to differentiate into functional insulin-producing cells. The current study aims to assess the differentiation potential of human pancreatic IPCs (islet-derived progenitor cells). IPCs were derived from four human donors and ...

journal_title：Cell biology international

authors： Zhang Y,Ren Z,Zou C,Wang S,Luo B,Li F,Liu S,Zhang YA

更新日期：2011-05-01 00:00:00

abstract：:In the past decades increasing lines of evidence have demonstrated that adipose tissue, as an endocrine organ plays a central role in metabolic homeostasis and its related maladies. CCAAT/enhancer-binding protein (C/EBP) family members and the nuclear receptor peroxisome proliferator-activated receptor gamma (PPARγ) w...

journal_title：Cell biology international

authors： Zhao XY,Chen XY,Zhang ZJ,Kang Y,Liao WM,Yu WH,Xiang AP

更新日期：2015-04-01 00:00:00

abstract：:Spermatogonia and sperm-like cells can be derived in vitro via the addition of RA (retinoic acid) to pluripotent ES and EG cells. At present, however, these cells have not been derived from unipotent cells. Here, we have generated premeiotic Stra8-positive cells from C2C12 myoblasts following treatment with 10 μM all-...

journal_title：Cell biology international

authors： Jia W,Cheng D,Chen S,Lei L,Wang H

更新日期：2011-04-01 00:00:00

abstract：:Calmodulin-like skin protein (CLSP) is a secreted peptide that is produced by skin keratinocytes and some related epithelial cells. It has previously been shown that CLSP is recruited via the bloodstream into the central nervous system where it likely exerts a neuroprotective effect against toxicity related to Alzheim...

journal_title：Cell biology international

authors： Takahara Y,Miyachi N,Nawa M,Matsuoka M

更新日期：2019-07-01 00:00:00

abstract：:Rb/E2F regulates many genes that encode proteins required for the cell cycle. Using affymetrix microarrays we previously identified genes regulated by the Rb proteins p130 and p107, many of which are involved in the cell cycle. Several genes with unknown functions were also repressed by p130 and p107, of which some ha...

journal_title：Cell biology international

authors： Date DA,Jacob CJ,Bekier ME,Stiff AC,Jackson MW,Taylor WR

更新日期：2007-12-01 00:00:00

abstract：:Cattle plays an important role in providing essential nutrients through meat production. Thus, we focused on epigenetic factors associated with meat yield. To investigate circulating miRNAs that are involved with meat yield and connect biofluids and longissimus dorsi (LD) muscle in Korean cattle, we performed analyses...

journal_title：Cell biology international

authors： Lee S,Park SJ,Cheong JK,Ko JY,Bong J,Baik M

更新日期：2017-07-01 00:00:00

abstract：:The mitogen activated protein kinases (MAPK) signaling cascade plays an important role in cell life. We proved that small interfering RNAs targeting MAPK1 (siRNA-2) could inhibit HeLa cell growth, but the effects of siRNA-2 on gene expression profile were unclear. Using Affymetrix GeneChip HG-U133A 2.0, we identified ...

journal_title：Cell biology international

authors： Huang C,Liu LY,Li ZF,Wang P,Ni L,Song LP,Xu DH,Song TS

更新日期：2008-09-01 00:00:00