Detection of potassium currents and regulation of multidrug resistance by potassium channels in human gastric cancer cells.

abstract：:Resistance to radiotherapy and chemotherapy has been a major problem of conventional cancer therapies, which consequently leads to cancer relapse and cancer-related death. It is known that cancer stem cells (CSCs) play a key role in therapy resistance and CSC-based targeted therapies have been considered as a powerful...

journal_title：Cell biology international

authors： Johari B,Rahmati M,Nasehi L,Mortazavi Y,Faghfoori MH,Rezaeejam H

更新日期：2020-12-01 00:00:00

abstract：:Stem cell therapy in recent years has gained much attention as the modern therapeutic approach to treat diseases. Mesenchymal stem cells (MSCs) are seen as the most reliable cells applied in therapy over other stem cells because of their versatility. Bone and cartilage diseases (osteo-diseases) are the major target of...

journal_title：Cell biology international

authors： Ghasroldasht MM,Irfan-Maqsood M,Matin MM,Bidkhori HR,Naderi-Meshkin H,Moradi A,Bahrami AR

更新日期：2014-10-01 00:00:00

abstract：:Periodontitis is a chronic inflammatory disease that results in the destruction of periodontal soft tissue and the resorption of alveolar bone. Evidence indicates that in diabetic patients, hyperglycemia suppresses periodontal ligament stem cell (PDLSC) functions and leads to difficulties in periodontal repair. The pr...

journal_title：Cell biology international

authors： Luo H,Zhu W,Mo W,Liang M

更新日期：2020-12-01 00:00:00

abstract：:Non-specific L-type calcium channel blockers, such as verapamil (> or =50 microM), induce metaphase-II (M-II) arrest and apoptosis in aged rat eggs cultured in Ca(2+)-deficient medium. However, the effects of extracellular Ca(2+) on verapamil-induced M-II arrest and apoptosis have not yet been reported. We have demons...

journal_title：Cell biology international

authors： Chaube SK,Tripathi A,Khatun S,Mishra SK,Prasad PV,Shrivastav TG

更新日期：2009-03-01 00:00:00

abstract：:DCs (dendritic cells) are the strongest professional APCs (antigen-presenting cells) to initiate immune responses against pathogens, but they are usually incompetent in initiating efficient immune responses in the progress of solid tumours. We have shown that Notch signalling plays a pivotal role in DC-dependent anti-...

journal_title：Cell biology international

authors： Feng F,Yang J,Tong L,Yuan S,Tian Y,Hong L,Wang W,Zhang H

更新日期：2012-03-01 00:00:00

abstract：:This study provides evidence that, in the soluble fraction from buffer-washed pea thylakoids, one form of soluble carbonic anhydrase (CA) is associated with rubisco in a stromal protein complex. On native-PAGE gels, it is present as a protein band with MW approximately 160 kDa. On SDS-PAGE gels, it is resolved as a si...

journal_title：Cell biology international

authors： Lazova GN,Stemler AJ

更新日期：2008-06-01 00:00:00

abstract：:Embryonic development depends on the normal invasion of trophoblast cells. Forkhead box C2 (FOXC2) is a member of Forkhead box family, which is involved in the tumor cells invasion. The aim of this study was to explore the roles of FOXC2 on the invasion of human trophoblast cells, and further study its molecular mecha...

journal_title：Cell biology international

authors： Zhang Y,Zhang Y

更新日期：2018-07-01 00:00:00

abstract：:While much evidence indicates a high degree of spatial organization in the nucleus, the underlying molecular structures that support it remain poorly characterized. By extracting with high concentrations of RNase A in a modification of the sequential extraction protocol of Penman, we have identified a novel intranucle...

journal_title：Cell biology international

authors： Padros MR,Giles DM,Suarez MD

更新日期：1997-06-01 00:00:00

abstract：:Here we report a homologue of the apolipoprotein D gene (AmphiApoD) in amphioxus, Branchiostoma belcheri tsingtauense, the first such finding in a basal chordate cephalochordate. The main features of the protein predicted from AmphiApoD are characteristic of the apolipoprotein D. Phylogenetic analysis places AmphiApoD...

journal_title：Cell biology international

authors： Wang L,Zhang S,Liu Z,Li H,Wang Y,Jiang S

更新日期：2007-01-01 00:00:00

abstract：:Fibrillin-1 is the major component of extracellular matrix microfibrils. Microfibrils dysfunction is responsible for the onset of various connective tissue diseases, including Marfan syndrome. Although ADAMTSL (a disintegrin and metalloproteinase with thrombospondin motifs-like) 6β is one of the fibrillin-1 binding pr...

journal_title：Cell biology international

authors： Orimoto A,Fukuda T

更新日期：2020-07-01 00:00:00

abstract：:Oxidative stress can be defined as the increase of oxidizing agents like reactive oxygen and nitrogen species, or the imbalance between the antioxidative defense mechanism and oxidants. Cell cycle checkpoint response can be defined as the arrest of the cell cycle functioning after damaging chemical exposure. This temp...

journal_title：Cell biology international

authors： Akcakaya H,Dal F,Tok S,Cinar SA,Nurten R

更新日期：2015-02-01 00:00:00

abstract：:The biosynthesis of interleukin-6 receptor (IL-6R) and gp130 in vitro was blocked using specific antisense oligonucleotides (ASO) in HepG2 liver cells and the efficacy of various ASOs was tested on the generation of IL-6-induced junB mRNA. We used three ASOs specific for the IL-6 receptor, three specific for gp130 and...

journal_title：Cell biology international

authors： Varga VL,Fülöp AK,Holub MC,Tóth S,Szalai C,Falus A

更新日期：2001-01-01 00:00:00

abstract：:The spatial distribution of acid membrane organelles and their relationships with normal and vacuolated transverse tubules has been studied in living frog skeletal muscle fibres using confocal microscopy. Acridine orange (AO) was used to evaluate acid compartments, while a lipophilic styryl dye, RH 414, was employed t...

journal_title：Cell biology international

authors： Krolenko SA,Adamyan SY,Belyaeva TN,Mozhenok TP

更新日期：2006-11-01 00:00:00

abstract：:To establish useful human normal cell lines, TERT (telomerase reverse transcriptase) cDNA was transfected into normal female lung fibroblast, TIG-1. After long-term-sub-cultivation of 74 individual clones selected for resistance to G418, we obtained 55 cultures with normal range of life span [75 PDL (population doubli...

journal_title：Cell biology international

authors： Kamada M,Kumazaki T,Matsuo T,Mitsui Y,Takahashi T

更新日期：2012-06-01 00:00:00

abstract：:Lysosomal permeability to potassium ions is an important property of the organelle. Influence of the membrane physical state on the potassium ion permeability of isolated lysosomes was assessed by measuring the membrane potential with bis(3-propyl-5-oxoisoxazol-4-yl)pentamethine oxonol and monitoring the lysosomal pro...

journal_title：Cell biology international

authors： Wang J,Zhang GJ

更新日期：2005-06-01 00:00:00

abstract：:Extracellular nucleotides cause neutrophil degranulation by activating the purinergic receptor subtype P2Y. However, the molecular mechanism involved in the signal pathway remains unknown. A hypothetical scheme suggesting that leukotriene(s) and leukotriene receptor(s) activation is required for extracellular nucleoti...

journal_title：Cell biology international

authors： Kannan S

更新日期：2003-01-01 00:00:00

abstract：:Pig endothelial cells are the first cells to interact with human immune components after organ xenotransplantation, which is a procedure currently considered to be the best treatment option for end-stage organ failure. It is, therefore, essential to study the mechanisms of molecular interaction between pig endothelial...

journal_title：Cell biology international

authors： Kim D,Kim JY,Koh HS,Lee JP,Kim YT,Kang HJ,Hwang WS,Kim YB,Lee JS,Ahn C

更新日期：2005-08-01 00:00:00

abstract：:The mitogen activated protein kinases (MAPK) signaling cascade plays an important role in cell life. We proved that small interfering RNAs targeting MAPK1 (siRNA-2) could inhibit HeLa cell growth, but the effects of siRNA-2 on gene expression profile were unclear. Using Affymetrix GeneChip HG-U133A 2.0, we identified ...

journal_title：Cell biology international

authors： Huang C,Liu LY,Li ZF,Wang P,Ni L,Song LP,Xu DH,Song TS

更新日期：2008-09-01 00:00:00

abstract：:Peroxisomicine A1 (PA1) is a potential antineoplastic agent with high and selective toxicity toward peroxisomes of tumor cells. Pexophagy is a selective autophagy process that degrades damaged peroxisomes; this process has been studied mainly in methylotrophic yeasts. There are two main modes of pexophagy in yeast: ma...

journal_title：Cell biology international

authors： Ortega-Martínez M,Gutiérrez-Dávila V,Niderhauser-García A,Salazar-Aranda R,Solís-Soto JM,Montes-de-Oca-Luna R,Jaramillo-Rangel G

更新日期：2020-03-01 00:00:00

abstract：:At the end of transcardial perfusions with ice-cold physiological saline for 30 min or with isoosmotic potassium chloride for 5 min, but immediately before perfusion fixation, condenser-discharge electric shocks were administered to rats through surface electrodes pressed onto the temporal muscles of the scalped skull...

journal_title：Cell biology international

authors： Kellermayer R,Zsombok A,Auer T,Gallyas F

更新日期：2006-02-01 00:00:00

abstract：:Observations made in live cells have clearly demonstrated that agonist-activated steroid/nuclear receptors reorganize in the nucleoplasm into hundreds of discrete speckled structures commonly referred to as nuclear foci. Subsequent studies have shown that nuclear foci are formed only with agonist- and not with pure an...

journal_title：Cell biology international

authors： Kumar S,Saradhi M,Chaturvedi NK,Tyagi RK

更新日期：2012-02-01 00:00:00

abstract：:The mdx mouse has been used as an animal model for human Duchenne muscular dystrophy (DMD). Unlike DMD, skeletal muscles of mdx mice undergo successful regeneration and do not show extensive fibrosis and functional impairment. Growth factors have been proposed to be involved in muscle growth and regeneration. We compa...

journal_title：Cell biology international

authors： Chen G,Bressler BH,Quinn LS

更新日期：1994-04-01 00:00:00

abstract：:Key to mitochondrial activities is the maintenance of mitochondrial morphology, specifically cristae structures formed by the invagination of the inner membrane that are enriched in proteins of the electron transport chain. In Saccharomyces cerevisiae , these cristae folds are a result of the membrane fusion activitie...

journal_title：Cell biology international

authors： Huddleston ME,Xiao N,Both AP,Gordon DM

更新日期：2019-08-23 00:00:00

abstract：:An acetylcholine (ACh) agonist, carbachol (Cch), causes hepatocytes to proliferate in the presence of hepatic nonparenchymal cells (HNPCs). To identify the HNPCs and ACh receptor subtypes involved in carbachol-induced hepatocyte proliferation (CIHP), we examined two types of vascular cells as candidates for HNPCs medi...

journal_title：Cell biology international

authors： Yoshimura R,Arai J,Endo Y

更新日期：2009-04-01 00:00:00

abstract：:δ-Catenin and β-catenin belong to different subfamilies of armadillo proteins but share some common binding partners, such as E-cadherin. This is the first study that demonstrated a novel common binding partner for δ-catenin and β-catenin, lymphoid enhancer factor-1 (LEF-1). We found that the N-terminus of δ-catenin (...

journal_title：Cell biology international

authors： He Y,Ki H,Kim H,Kim K

更新日期：2015-08-01 00:00:00

abstract：:The objective of this study was to test the hypothesis that cytoskeletal actin fragmentation is mediated through caspase-2, specifically examining the ability of a caspase-2 inhibitor to interfere with actin fragmentation, in comparison with a caspase-3 inhibitor. Cardiomyocytes were cultured from embryonic chick hear...

journal_title：Cell biology international

authors： Kong JY,Rabkin SW

更新日期：2004-01-01 00:00:00

abstract：:Heat shock proteins (HSPs) are molecular chaperones involved in protein folding, assembly and transport, and which play critical roles in the regulation of cell growth, survival and differentiation. We set out to test the hypothesis that HSP27 protein is expressed in the human testes and its expression varies with the...

journal_title：Cell biology international

authors： Adly MA,Assaf HA,Hussein MR

更新日期：2008-10-01 00:00:00

abstract：:Large numbers of autogenous melanocytes (Mcs) are required when conducting studies on tissue engineering of skin and performing surgical treatment of depigmentation diseases. This study was conducted to explore the possibility of inducing differentiation of bone marrow mesenchymal stem cells (MSCs) into Mcs as a means...

journal_title：Cell biology international

authors： Mei X,Sun Y,Wu Z,Pan W,Zhu J,Shi W

更新日期：2015-07-01 00:00:00

abstract：:Non-transformed epitheliocytes and fibroblasts undergo modulations between the less polarised and more polarised phenotypes depending on the nature of the substrate. In contrast, transformed cells express polarised phenotype regardless of the substrate. ...

journal_title：Cell biology international

authors： Moizhess TG,Vasiliev JM

更新日期：2001-01-01 00:00:00

abstract：:The spreading behaviour of dissociated hypoblast cells on and besides a band of aligned fibrils associated with the basal lamina of the epiblast was investigated by the use of scanning electron microscopy. A horse-shaped band of aligned fibrils, first demonstrated by Wakely and England (1979), is present during the ga...

journal_title：Cell biology international

authors： Andries L,Harrisson F,Vakaet L

更新日期：1994-07-01 00:00:00