High-glucose concentration aggravates TNF-alpha-induced cell viability reduction in human CD146-positive periodontal ligament cells via TNFR-1 gene demethylation.

abstract：:Key to mitochondrial activities is the maintenance of mitochondrial morphology, specifically cristae structures formed by the invagination of the inner membrane that are enriched in proteins of the electron transport chain. In Saccharomyces cerevisiae , these cristae folds are a result of the membrane fusion activitie...

journal_title：Cell biology international

authors： Huddleston ME,Xiao N,Both AP,Gordon DM

更新日期：2019-08-23 00:00:00

abstract：:Local anesthetic of bupivacaine may inhibit neurite outgrowth and induce apoptosis in mouse dorsal root ganglia (DRG) neurons. In this work, we intended to investigate the functional role of microRNA 26a (miR-26a) in regulating bupivacaine-induced nerve injury in DRG neurons. DRG neurons were extracted from C57BL/6 mi...

journal_title：Cell biology international

authors： Cui C,Xu G,Qiu J,Fan X

更新日期：2015-08-01 00:00:00

abstract：:Polycystin-2 (PC-2), a protein encoded by PKD2 and involved in autosomal dominant polycystic kidney disease (ADPKD), is a non-selective cationic channel recently implicated in the function of primary cilia. We recently constructed a new animal model in the form of a transgenic mouse with a BAC-containing human PKD2 in...

journal_title：Cell biology international

authors： Burtey S,Riera M,Ribe E,Pennenkamp P,Rance R,Luciani J,Dworniczak B,Mattei MG,Fontés M

更新日期：2008-10-01 00:00:00

abstract：:Oral squamous cell carcinoma (OSCC) is a serious global health problem. Recently, accumulating microRNA (miRNA) has emerged as crucial players in the development and progression of carcinomas including OSCC. Our study aimed to further investigate the roles of miR-140-5p in OSCC tumorigenesis and related molecular basi...

journal_title：Cell biology international

authors： Peng M,Pang C

更新日期：2019-08-08 00:00:00

abstract：:Restriction Endonucleases (REs) may recognize, cleave and remove DNA from fixed chromatin producing specific chromosome banding patterns. However, the modifications produced in the chromatin fibre are not easy to evaluate and compare. The aim of the present investigation was to visualize differences resulting in the t...

journal_title：Cell biology international

authors： Gosálvez J,López-Fernández C,Fernández JL,Goyanes VJ,Buño I

更新日期：1996-03-01 00:00:00

abstract：:Ca(2+)mobilization induced by ATP, isoproterenol and the Ca(2+)-ATPase inhibitor thapsigargin in the human submandibular duct cell line A253 was investigated using the Ca(2+)-sensitive fluorescent indicator fura-2. ATP and isoproterenol increased cytosolic free Ca(2+)([Ca(2+)](i)) and subsequent exposure to thapsigarg...

journal_title：Cell biology international

authors： Andersson C,Zhang AL,Roomans GM

更新日期：2000-01-01 00:00:00

abstract：:Growing evidence has shown that apelin/APJ system functions as a critical mediator of cardiac development as well as cardiovascular function. Here, we investigated the role of apelin in the cardiomyogenic differentiation of mesenchymal stem cells derived from Wharton's jelly of human umbilical cord in vitro. In this r...

journal_title：Cell biology international

authors： Wang L,Zhu ZM,Zhang NK,Fang ZR,Xu XH,Zheng N,Gao LR

更新日期：2016-05-01 00:00:00

abstract：:As experimental evidence suggests that leptin may have direct effects on peripheral tissues, we investigated some of the transductional molecules induced by leptin in C2C12 cells. In immunoprecipitation experiments using anti-p85 antibodies (a regulatory subunit of phosphatidylinositol-3-kinase; PI3K), we observed a s...

journal_title：Cell biology international

authors： Maroni P,Bendinelli P,Piccoletti R

更新日期：2005-07-01 00:00:00

abstract：:This review summarizes original and literature data on changes in the ultrastructure of major cell organelles during apoptosis obtained by transmission electron microscopy. Organelles that make the most crucial contribution to the initiation of apoptosis: plasma membrane, mitochondria, proteasomes, Golgi apparatus, an...

journal_title：Cell biology international

authors： Snigirevskaya ES,Komissarchik YY

更新日期：2019-07-01 00:00:00

abstract：:Cardiac differentiation of human pluripotent stem cells may be induced under chemically defined conditions, wherein the regulation of Wnt/β-catenin pathway is often desirable. Here, we examined the effect of trolox, a vitamin E analog, on the cardiac differentiation of human embryonic stem cells (hESCs). 6-Hydroxy-2,5...

journal_title：Cell biology international

authors： Choe MS,Yeo HC,Bae CM,Han HJ,Baek KM,Kim JS,Lim KS,Shin IS,Chang W,Yun SP,Lee HJ,Lee MY

更新日期：2019-07-10 00:00:00

abstract：:To identify the molecular basis by which nonpermissive temperature (NPT) induces cell differentiation in Sertoli TTE3 cells harboring temperature-sensitive SV40 large T-antigen, we performed global scale microarray and computational gene network analyses. In TTE3 cells, inactivation of the large T-antigen by a NPT at ...

journal_title：Cell biology international

authors： Tabuchi Y,Takasaki I,Suto A,Kondo T,Suzuki Y,Obinata M

更新日期：2007-10-01 00:00:00

abstract：:Type I diabetes is characterized by the deficiency of endocrine beta cells in the pancreatic islets of Langerhans and transplantation of islet cells can be an effective therapeutic approach. Embryonic stem cells can be differentiated into any cell type, and therefore represent an unlimited source of islet cells for th...

journal_title：Cell biology international

authors： Chen C,Zhang Y,Sheng X,Huang C,Zang YQ

更新日期：2008-04-01 00:00:00

abstract：:The protein encoded by the proto-oncogene c-fos is constitutively nuclear in most cell types analyzed. It has a predicted molecular weight of about 55 kDa. Proteins with a molecular weight above 40 kDa cannot enter the nucleus passively. Our interest was to study which regions in the protein are involved in the nuclea...

journal_title：Cell biology international

authors： Campos MA,Kroon EG,Gentz R,Ferreira PC

更新日期：1999-01-01 00:00:00

abstract：:ES (embryonic stem)-derived cells have been investigated in many animal models of severe injury and degenerative disease. However, few studies have examined the ability of ES-derived cells to improve functional outcome following partially damaged breast and also the modification of mammary tissue to produce costly pro...

journal_title：Cell biology international

authors： Huang HJ,Gao QS,Qian YG,Zhang YD,Tao BF,Xiang M,Peng J,Jiang SW,Hause B

更新日期：2010-10-01 00:00:00

abstract：:The cytokertatins in respiratory epithelial cells (REC) of human nasal polyps and turbinates were analyzed by immunohistochemistry. Cytokeratin 19 (CK19) was present in all REC, CK5 and 14 were expressed primarily in basal cells, and CK7, 8, and 18 were found in suprabasal cells. Differences in cytoplasmic locations w...

journal_title：Cell biology international

authors： Hicks W Jr,Ward R,Edelstein D,Hall L 3rd,Albino A,Hard R,Asch B

更新日期：1995-04-01 00:00:00

abstract：:DCs (dendritic cells) are the strongest professional APCs (antigen-presenting cells) to initiate immune responses against pathogens, but they are usually incompetent in initiating efficient immune responses in the progress of solid tumours. We have shown that Notch signalling plays a pivotal role in DC-dependent anti-...

journal_title：Cell biology international

authors： Feng F,Yang J,Tong L,Yuan S,Tian Y,Hong L,Wang W,Zhang H

更新日期：2012-03-01 00:00:00

abstract：:Electrotonic coupling among neurons in the vertebrate, and more specifically the mammalian, brain has now been demonstrated to exist in all major brain subdivisions and in the spinal cord. For many of these brain areas, recent studies have investigated the possibilities of modulation of that coupling by synaptically r...

journal_title：Cell biology international

authors： Hatton GI

更新日期：1998-11-01 00:00:00

abstract：:Glutamyl aminopeptidase (GluAP, EC 3.4.11.7, ENPEP) is a 130-kDa homodimeric zinc metallopeptidase which specifically cleaves the N-terminal glutamate or aspartate residue of peptidic substrates such as cholecystokinin-8 or angiotensin (Ang) II, in vitro. We used a DNA microarray hybridization (Genechip Rat Expression...

journal_title：Cell biology international

authors： Wu Y,Xiao J,Wu L,Tian W,Liu L

更新日期：2008-07-01 00:00:00

abstract：:Arginine vasopressin (AVP)-induced tyrosine phosphorylation was studied in a rat smooth muscle cell line, A-10, by western blotting, using a monoclonal antibody against phosphotyrosine. AVP stimulated the phosphorylation of several cellular proteins of molecular mass 60-130 kDa in a time- and dose-dependent manner. Ph...

journal_title：Cell biology international

authors： Gonzalez CB,Reyes CE,Figueroa CD,Barra V,Troncoso S

更新日期：1999-01-01 00:00:00

abstract：:The purpose of this study was three fold: (1) to reveal the implications of Wnt5A for cytokine and chemokine production by human ovarian cancer cell line SKOV-3 cells, (2) to determine the influence of Wnt5A on chemotactic SKOV-3 cell migration, and (3) to assess the effect of inflammatory mediators on Wnt5A expressio...

journal_title：Cell biology international

authors： Arabzadeh S,Hossein G,Zarnani AH

更新日期：2016-02-01 00:00:00

abstract：:The aim of this study was to obtain membrane-bound alkaline phosphatase from osteoblastic-like cells of human alveolar bone. Cells were obtained by enzymatic digestion and maintained in primary culture in osteogenic medium until subconfluence. First passage cells were cultured in the same medium and at 7, 14, and 21 d...

journal_title：Cell biology international

authors： Simão AM,Beloti MM,Rosa AL,de Oliveira PT,Granjeiro JM,Pizauro JM,Ciancaglini P

更新日期：2007-11-01 00:00:00

abstract：:The purpose of the study was to examine mechanisms controlling cell cycle progression/arrest and differentiation of mouse C2C12 myoblasts exposed to long-chain saturated fatty acid salt, palmitate. Treatment of proliferating myoblasts with palmitate (0.1 mmol/l) markedly decreased myoblast number. Cyclin A and cyclin ...

journal_title：Cell biology international

authors： Grabiec K,Milewska M,Błaszczyk M,Gajewska M,Grzelkowska-Kowalczyk K

更新日期：2015-09-01 00:00:00

abstract：:Metallothioneins (MTs) are thought to participate in a wide variety of physiological roles, but the mechanisms involved are still unclear. The study was designed to examine the possible factors related to these mechanisms. Methods, including transfection, MTT assay and flow cytometry, were used to investigate the effe...

journal_title：Cell biology international

authors： Li J,Liu Y,Ru B

更新日期：2005-10-01 00:00:00

abstract：:Induction of HO-1 protein can have both beneficial and detrimental effects for cells, including regulating proliferation and apoptosis of several tumours. We have investigated the regulation of HO-1, p38MAPK and mTOR in the context of proliferation, cell cycle events and apoptosis of oesophageal squamous cell carcinom...

journal_title：Cell biology international

authors： Hu JL,Xiao L,Li ZY,Wang Q,Chang Y,Jin Y

更新日期：2013-06-01 00:00:00

abstract：:Aerenchyma is a plant tissue characterized by prominent intercellular spaces facilitating gas diffusion between roots and the aerial environment. The classical formation of intercellular spaces is thought to be the result of schizogeny and lysogeny during development of wetland species and in some dry-land species in ...

journal_title：Cell biology international

authors： Kordyum EL,Shevchenko GV,Brykov VO

更新日期：2019-09-01 00:00:00

abstract：:The exon 16-encoded juxtamembrane (JM) domain of human insulin receptor (hIR) harbors the NPEY motif which couples the insulin-activated hIR kinase to downstream signal transduction molecules. We sought to determine if signal transduction requires the entire exon 16-encoded 22-amino acid JM domain. Transfected CHO cel...

journal_title：Cell biology international

authors： Sattar AA,Berhanu C,Gebreselassie S,Berhanu P

更新日期：2007-08-01 00:00:00

abstract：:Tissue engineering of bone has been increasingly used in the bone defect repair. To generate osteoblasts is a major approach, and here we have examined ways of improving the efficiency of producing osteoblasts. Adipose stem cells (ADSC) were prepared from rat mesentery tissue, and transfected with Cbfa1 gene vector or...

journal_title：Cell biology international

authors： Wang L,Wang H,Xu X,Wang D,Liu H

更新日期：2013-11-01 00:00:00

abstract：:While Bcl-2 protein is involved in the regulation of apoptosis, recent research showed that Beclin1, described as the essential autophagy effector and haploinsufficient tumor suppressor, was originally isolated as a Bcl-2 interacting protein. Beclin1 interacts with Bcl-2 through a BH3 domain; nevertheless, the functio...

journal_title：Cell biology international

authors： Du Y,Ji X

更新日期：2014-10-01 00:00:00

abstract：:The spatial distribution of acid membrane organelles and their relationships with normal and vacuolated transverse tubules has been studied in living frog skeletal muscle fibres using confocal microscopy. Acridine orange (AO) was used to evaluate acid compartments, while a lipophilic styryl dye, RH 414, was employed t...

journal_title：Cell biology international

authors： Krolenko SA,Adamyan SY,Belyaeva TN,Mozhenok TP

更新日期：2006-11-01 00:00:00

abstract：:An experimental model of leg lengthening was used to study the morphology of, the collagenous proteins present, and the collagen genes expressed in the regenerating tissue following 20% lengthening at four different distraction rates. At a distraction rate of 0.3 mm/day (8 weeks distraction), the regenerate consists o...

journal_title：Cell biology international

authors： Li G,Virdi AS,Ashhurst DE,Simpson AH,Triffitt JT

更新日期：2000-01-01 00:00:00