Reduced expression of the BRCA1 gene and increased chromosomal instability in MCF-7 cell line.

abstract：:Type I diabetes is characterized by the deficiency of endocrine beta cells in the pancreatic islets of Langerhans and transplantation of islet cells can be an effective therapeutic approach. Embryonic stem cells can be differentiated into any cell type, and therefore represent an unlimited source of islet cells for th...

journal_title：Cell biology international

authors： Chen C,Zhang Y,Sheng X,Huang C,Zang YQ

更新日期：2008-04-01 00:00:00

abstract：:Low-temperature stress during microspore development alters cellular organization in rice anthers. The major cellular damage includes unusual starch accumulation in the plastids of the endothecium in postmeiotic anthers, abnormal vacuolation and hypertrophy of the tapetum, premature callose (1,3-beta-glucan) breakdown...

journal_title：Cell biology international

authors： Al Mamun E,Cantrill LC,Overall RL,Sutton BG

更新日期：2010-03-29 00:00:00

abstract：:The effects of NO in its environment may vary considerably depending on various factors. This study shows oxidative mechanism of cellular membrane alterations, which is not associated with triggering of ONOOH generation but is induced by pure NO. Our investigation examined the influence of low concentration of NO (0.1...

journal_title：Cell biology international

authors： Brzeszczynska J,Gwozdzinski K

更新日期：2008-01-01 00:00:00

abstract：:Key to mitochondrial activities is the maintenance of mitochondrial morphology, specifically cristae structures formed by the invagination of the inner membrane that are enriched in proteins of the electron transport chain. In Saccharomyces cerevisiae , these cristae folds are a result of the membrane fusion activitie...

journal_title：Cell biology international

authors： Huddleston ME,Xiao N,Both AP,Gordon DM

更新日期：2019-08-23 00:00:00

abstract：:Human tissues are sophisticated ensembles of various distinct cell types encapsulated in the biomechanical cues of the extracellular matrix. It has been known matrix stiffness plays a pivot role in cellular events and tissue-scale biological processes. Thus, materials that can mimic mechanical environments of tissues ...

journal_title：Cell biology international

authors： Zhao H,Xu K,Zhu P,Wang C,Chi Q

更新日期：2019-02-01 00:00:00

abstract：:Adaptation of cardiomyocytes to chronic hypoxia in cyanotic patients remains unclear. Mitochondrial biogenesis is enhanced in myocardium from cyanotic patients, which is possibly an adaptive response. Erythropoietin (EPO) in blood and its receptor (EPOR) on cardiomyocytes are upregulated by chronic hypoxia, suggesting...

journal_title：Cell biology international

authors： Qin C,Zhou S,Xiao Y,Chen L

更新日期：2014-03-01 00:00:00

abstract：:Previous work on five cell types isolated from the bovine corpus luteum showed that the mass of acetylated microtubules (acet-MTs) in interphase differed. Endothelial cells, termed type 3, showed few acet-MTs, whereas the interphase cytoskeleton of granulosal-like cells, termed type 5, was rich in acet-MTs. In the pre...

journal_title：Cell biology international

authors： Wolf KW,Spanel-Borowski K

更新日期：1995-01-01 00:00:00

abstract：:Mitomycin C (MMC) treatment has been used to arrest cell proliferation but not much is known about the effect of MMC on human foreskin fibroblasts (HFF) used as feeders for human embryonic stem cells (hESC). We tested the ability of MMC to stop the proliferation of HFF and to induce apoptosis. MMC inhibited the prolif...

journal_title：Cell biology international

authors： Nieto A,Cabrera CM,Catalina P,Cobo F,Barnie A,Cortés JL,Barroso del Jesus A,Montes R,Concha A

更新日期：2007-03-01 00:00:00

abstract：:Cell therapy and regenerative medicine are potentially two of the most exciting aspects of the novel therapeutic methods currently under development. However, these treatments present a number of important biosafety issues, like the possible transmission of microorganisms to the recipients. The most common potential f...

journal_title：Cell biology international

authors： Cobo F,Cortés JL,Cabrera C,Nieto A,Concha A

更新日期：2007-09-01 00:00:00

abstract：:DNA is constantly being damaged, either by endogenous or exogenous genotoxins. In that regard, DNA repair activities are essential for maintaining genomic stability and to life itself. Mutations in genes encoding DNA repair proteins cause severe human syndromes, but DNA repair defects have also been linked to several ...

journal_title：Cell biology international

authors： Prates Mori M,de Souza-Pinto NC

更新日期：2018-06-01 00:00:00

abstract：:Periodontitis is a chronic inflammatory disease that results in the destruction of periodontal soft tissue and the resorption of alveolar bone. Evidence indicates that in diabetic patients, hyperglycemia suppresses periodontal ligament stem cell (PDLSC) functions and leads to difficulties in periodontal repair. The pr...

journal_title：Cell biology international

authors： Luo H,Zhu W,Mo W,Liang M

更新日期：2020-12-01 00:00:00

abstract：:Genetic analysis has strongly implicated human FHIT (Fragile Histidine Triad) as a tumor suppressor gene, being mutated in a large proportion of early-stage cancers. The functions of the FHIT protein have, however, remained elusive. Here, we investigated aph1+ , the fission yeast homolog of FHIT, for functions related...

journal_title：Cell biology international

authors： Sjölander JJ,Sunnerhagen P

更新日期：2020-02-01 00:00:00

abstract：:We review Don Gilbert's pioneering seminal contributions that both detailed the mathematical principles and the experimental demonstration of several of the key dynamic characteristics of life. Long before it became evident to the wider biochemical community, Gilbert proposed that cellular growth and replication neces...

journal_title：Cell biology international

authors： Gilbert K,Hammond KD,Brodsky VY,Lloyd D

更新日期：2020-06-01 00:00:00

abstract：:Hypoxia-inducible factor-1α (HIF-1α) and hepatocyte growth factor (HGF) play important roles in postnatal neovascularization. However, the interaction of these two pathways is not fully understood. The present study utilized CoCl(2) treated-endothelial progenitor cells (EPCs) (EPCs exposure to CoCl(2) are under mimic ...

journal_title：Cell biology international

authors： Yu F,Lin Y,Zhan T,Chen L,Guo S

更新日期：2015-03-01 00:00:00

abstract：:The anti-desmin monoclonal antibodies (MAbs) DSB389, AC54, and DSB860 recognize intermediate filaments (IFs) and nuclear antigens that appear granular, locate around chromosomes, and are insoluble following 0.5% Triton X-100 and cetyltrimethylammonium bromide (CTAB) extraction. Nuclear antigens of the MAbs were search...

journal_title：Cell biology international

authors： Kamei H

更新日期：1996-11-01 00:00:00

abstract：:Annexin I is an abundant cytosolic protein in human neutrophils. Besides its intracellular location, annexin I is found as an extracellular protein and the pathway for secretion has been of interest since the protein lacks a signal sequence for secretion. It was recently shown that annexin I is stored in the secretory...

journal_title：Cell biology international

authors： Movitz C,Dahlgren C

更新日期：2001-01-01 00:00:00

abstract：:A number of pathophysiological conditions are related to iron metabolism disturbances. Some of them are well known, others are newly discovered or special. Hepcidin is a newly identified iron metabolism regulating hormone, which could be a promising biomarker for many disorders. In this review, we provide background i...

journal_title：Cell biology international

authors： Miseta A,Nagy J,Nagy T,Poór VS,Fekete Z,Sipos K

更新日期：2015-11-01 00:00:00

abstract：:A significant decrease in tissue pH or acidosis is a common feature of numerous diseases, including RA (rheumatoid arthritis). Cartilage homoeostasis is profoundly affected by local acidosis in the joints. The diuretic, amiloride, is neuroprotective in models of cerebral ischaemia, a property attributable to the inhib...

journal_title：Cell biology international

authors： Rong C,Chen FH,Jiang S,Hu W,Wu FR,Chen TY,Yuan FL

更新日期：2012-07-01 00:00:00

abstract：:Bradykinin (1 microM) and histamine (100 microM) evoked an initial transient increase and a subsequent sustained increase in intracellular Ca(2+) concentration ([Ca(2+)](i)) in fura-2-loaded human gingival fibroblasts, which may be attributed to Ca(2+) release from intracellular stores and Ca(2+) entry from extracellu...

journal_title：Cell biology international

authors： Ogata Y,Nakao S,Shimizu E,Matsuda-Honjyo Y,Yamazaki M,Furuyama S,Sugiya H

更新日期：2003-01-01 00:00:00

abstract：:Insulin resistance (IR) is a hallmark of type 2 diabetes mellitus (T2DM). This study aimed to explore the effects of rapamycin, a specific inhibitor of kinase mammalian target of rapamycin (mTOR), on IR in T2DM rats, and to validate whether the underlying mechanism was associated with autophagy. In this study, the mod...

journal_title：Cell biology international

authors： Zhou W,Ye S

更新日期：2018-09-01 00:00:00

abstract：:Adipose tissue is a potential site of retinoic acid (RA) action, but its physiological significance remains to be clarified. We have examined the effect of all-trans retinoic acid (ATRA) on growth and differentiation of preadipocytes, and on adipokine gene expression in mature adipocytes using human preadipocyte cell ...

journal_title：Cell biology international

authors： Morikawa K,Hanada H,Hirota K,Nonaka M,Ikeda C

更新日期：2013-01-01 00:00:00

abstract：:We investigated the effect of triptolide (TP) on spinal cord injury (SCI), and its underlying mechanism. Following the establishment of the SCI model using YFP H-line transgenic mice, TP was intraperitoneally injected at a dose of 0.2 mg/kg once daily for 7 days. Behavioral tests, Nissl staining, and hematoxylin-eosin...

journal_title：Cell biology international

authors： Zhu N,Ruan J,Yang X,Huang Y,Jiang Y,Wang Y,Cai D,Geng Y,Fang M

更新日期：2020-03-01 00:00:00

abstract：:A combination of in vivo UV light-induced crosslinking of nucleic acids to proteins and in vitro label transfer assay was applied to investigate specific interactions between AU-rich sequences (ARE) in the 3' UTR of lymphokine mRNAs and cytoplasmic AU-rich sequence element binding proteins (AUBP) in normal human lymph...

journal_title：Cell biology international

authors： Henics T,Nagy E,Rigby WF

更新日期：1995-09-01 00:00:00

abstract：:The interaction of NO and O2- free radicals generated from PMA (phorbol myristate acetate)-stimulated PMN (polymorphonuclear leukocytes) was studied by a nitroxide spin trap, DMPO (5,5-dimethyl-1-pyrroline-1-oxide). It was found that addition of L-arginine to the system would significantly decrease the trapped O2- by ...

journal_title：Cell biology international

authors： Zhao BL,Wang JC,Hou JW,Xin WJ

更新日期：1996-05-01 00:00:00

abstract：:MMP-9 participates in tumour growth, invasion, metastasis and vascularisation. Thus, inhibition of MMP-9 may be involved in the process of tumourigenesis. We have investigated the effect of RNAi-mediated MMP-9 silencing on inhibiting invasion and migration of mouse melanoma cell B16. A specific and optimised siRNA vec...

journal_title：Cell biology international

authors： Tang ZY,Liu Y,Liu LX,Ding XY,Zhang H,Fang LQ

更新日期：2013-08-01 00:00:00

abstract：:The spreading behaviour of dissociated hypoblast cells on and besides a band of aligned fibrils associated with the basal lamina of the epiblast was investigated by the use of scanning electron microscopy. A horse-shaped band of aligned fibrils, first demonstrated by Wakely and England (1979), is present during the ga...

journal_title：Cell biology international

authors： Andries L,Harrisson F,Vakaet L

更新日期：1994-07-01 00:00:00

abstract：:The present study was undertaken to test the reproducible formation of the extended chromatin fibres (ECF), beads and superbeads, and detect molecular order and crystallinity by optical anisotropies in those structures. Chicken erythrocyte smears and mouse liver cell imprints were treated with 2.0-3.0 m NaCl solution ...

journal_title：Cell biology international

authors： de Campos Vidal B

更新日期：2000-01-01 00:00:00

abstract：:The expression and immunohistochemical localization of galectin-3, a beta-galactoside-binding protein, was studied in several mouse tissues. Galectin-3 expression was low in the cerebrum, heart, and pancreas, and moderate in the liver, ileum, kidney, and adrenal gland. High expression of galectin-3 was found in the lu...

journal_title：Cell biology international

authors： Kim H,Lee J,Hyun JW,Park JW,Joo HG,Shin T

更新日期：2007-07-01 00:00:00

abstract：:The intranucleolar chromatin has been detected by feeding HeLa cells with bromodeoxyuridine and then using an immunocytochemical technique for its detection at the ultrastructural level. Labelling was mainly observed on the dense fibrillar component (DFC), which surrounds the fibrillar centres (FC). Labelling could al...

journal_title：Cell biology international

authors： Ghosh S,Paweletz N

更新日期：1998-01-01 00:00:00

abstract：:Grafting material for vaginal reconstruction commonly includes the bowel, peritoneum, skin, and amniotic membrane. Bone marrow mesenchymal stem cells (MSCs) have the potential of multilineage differentiation into a variety of cells and have been widely explored in tissue engineering. In the current study, we examined ...

journal_title：Cell biology international

authors： Li Y,Liu F,Zhang Z,Zhang M,Cao S,Li Y,Zhang L,Huang X,Xu Y

更新日期：2015-11-01 00:00:00